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1. 发明申请

WO2005067820A2 OSTIUM STENT SYSTEM 审中-公开
标题翻译： OSTIUM STENT系统
公开(公告)号：WO2005067820A2
公开(公告)日：2005-07-28
申请号：PCT/US2005/000457
申请日：2005-01-07
申请人： MEDTRONIC VASCULAR INC
发明人： GOSHGARIAN, Justin
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/848 , A61F2/86 , A61F2/915 , A61F2/958 , A61F2002/821 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078
摘要： An ostium stent system includes a stent having a tubular body at the distal portion of the stent and a flaring portion at the proximal portion of the stent. A restraining structure that deploys the flaring portion covers only the proximal portion of the stent, providing a low profile for smooth delivery of the stent to the treatment site. The flaring portion comprises at least one flaring member which each comprise a short segment and a long segment. In an unexpanded configuration, each short and long segment are parallel to a longitudinal axis of the tubular body. When the flaring portion is deployed, each short segment remains parallel while each long segment becomes perpendicular to the longitudinal axis of the tubular body. The short segments therefore absorb the radial force resulting from deployment of the long segments and thereby prevent the stent from lifting off the balloon.
摘要翻译：口支架系统包括支架，其在支架的远端部分具有管状体，在支架的近端部分具有扩口部。展开扩口部分的约束结构仅覆盖支架的近端部分，提供了将支架平滑地输送到治疗部位的低轮廓。扩口部分包括至少一个扩口构件，每个扩口构件包括短段和长段。在未膨胀的构造中，每个短段和长段平行于管状体的纵向轴线。当扩口部分展开时，每个短节段保持平行，而每个长节段变得垂直于管状体的纵向轴线。因此，短段因此吸收由长部段展开而产生的径向力，从而防止支架从气囊上脱落。

2. 发明申请

WO2004078405A1 METHOD FOR MANUFACTURING AN ENDOVASCULAR SUPPORT DEVICE USING TUMBLING OPERATION TO ROUND EDGES OF THE STENT 审中-公开
标题翻译：使用手术操作固定支架的血管内支架装置的方法
公开(公告)号：WO2004078405A1
公开(公告)日：2004-09-16
申请号：PCT/US2003/041649
申请日：2003-12-30
申请人： MEDTRONIC VASCULAR, INC.
发明人： DOLAN, Mark , GOSHGARIAN, Justin
IPC分类号： B23K26/08
CPC分类号： B23K26/0823 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2230/0054 , B23K26/1476 , B23K2203/42 , B23K2203/50 , B24B31/02 , B24B31/10 , Y10S623/901 , Y10T29/49995 , Y10T83/0596 , Y10T83/384
摘要： A method for manufacturing an endovascular support device comprises positioning a generally tubular member made of an implantable metal and having a generally cylindrical wall in a working relationship with a laser beam. A desired pattern is cut (step 70) in the generally cylindrical wall in order to produce a stent having a plurality of openings and a plurality of edges. The stent is tumbled (step 74) in a medium to round its edges and, in turn, to produce more rounded cross-sections of stent elements.
摘要翻译：一种用于制造血管内支持装置的方法包括定位由可植入金属制成的大致管状构件，并且具有与激光束工作关系的大致圆柱形壁。在大致圆柱形的壁中切割所需的图案（步骤70），以便制造具有多个开口和多个边缘的支架。将支架在介质中翻转（步骤74）以使其边缘绕过，并且继而产生更圆的支架元件的横截面。

3. 发明申请

WO2007121072A2 SEAL FOR ENHANCED STENTED VALVE FIXATION 审中-公开
标题翻译：密封用于增强阀门固定
公开(公告)号：WO2007121072A2
公开(公告)日：2007-10-25
申请号：PCT/US2007/065649
申请日：2007-03-30
申请人： MEDTRONIC VASCULAR, INC. , BIRDSALL, Matthew , DOLAN, Mark , GOSHGARIAN, Justin , KRIVORUCHKO, Michael , LESSAR, Joseph , UNTEREKER, Darrell , URBANSKI, Peter
发明人： BIRDSALL, Matthew , DOLAN, Mark , GOSHGARIAN, Justin , KRIVORUCHKO, Michael , LESSAR, Joseph , UNTEREKER, Darrell , URBANSKI, Peter
IPC分类号： A61F2/24 , A61L24/00
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2002/9528 , A61F2210/0061 , A61F2250/006 , A61F2250/0069 , A61L24/0031 , A61L24/08 , C08L5/08
摘要： A valve replacement system that can be used for treating abnormalities of the right ventricular outflow tract includes a prosthetic valve device having a sealant contacting at least a portion of the outer surface of the valve device. The sealant may be breakable, and may be a hydrogel, an expandable hydrogel, or a solid. One embodiment of the invention includes a flowable sealant that is injected within the vascular system. Another embodiment of the invention includes a method for replacing a pulmonary valve that includes forming a seal around the exterior surface of a replacement valve and preventing blood flow around the replacement valve.
摘要翻译：可用于治疗右心室流出道异常的瓣膜置换系统包括具有接触阀装置的外表面的至少一部分的密封剂的人造瓣膜装置。密封剂可以是可破裂的，并且可以是水凝胶，可膨胀水凝胶或固体。本发明的一个实施方案包括注射在血管系统内的可流动的密封剂。本发明的另一实施例包括一种用于替换肺动脉瓣膜的方法，该方法包括在置换瓣膜的外表面周围形成密封并防止置换瓣膜周围的血液流动。

4. 发明申请

WO2007117726A3 HINGED STENT 审中-公开
公开(公告)号：WO2007117726A3
公开(公告)日：2007-10-18
申请号：PCT/US2007/060256
申请日：2007-01-09
申请人： MEDTRONIC VASCULAR, INC. , GOSHGARIAN, Justin
发明人： GOSHGARIAN, Justin
IPC分类号： A61F2/90
摘要： A stent delivery system is provided that comprises an inner member and an expandable balloon mounted on the inner member. A stent, which is mounted around at least a portion of the expandable balloon, comprises a plurality of alternating, hingedly-coupled crown sections and strut sections. Each adjacent crown section and strut section is coupled together via a hinge comprising a region having a thickness substantially less than that of the adjacent crown section and strut section.

5. 发明申请

WO2009061625A1 STENT WITH IMPROVED MECHANICAL PROPERTIES 审中-公开
标题翻译：具有改进的机械性能的STENT
公开(公告)号：WO2009061625A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/081184
申请日：2008-10-24
申请人： MEDTRONIC VASCULAR INC. , KRIVORUCHKO, Michael , BIRDSALL, Matthew , PELLEGRINI, Gianfranco , GOSHGARIAN, Justin , ALLEN, Jeffrey
发明人： KRIVORUCHKO, Michael , BIRDSALL, Matthew , PELLEGRINI, Gianfranco , GOSHGARIAN, Justin , ALLEN, Jeffrey
IPC分类号： A61F2/90 , A61F2/88
CPC分类号： A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91558 , A61F2220/0058 , A61F2250/0036
摘要： A stent (10) includes a central portion (12) having a first waveform. The first waveform is wrapped around a longitudinal axis of the stent at a pitch to define a plurality of helical turns. The stent also includes an end segment (14) connected to one end of the central portion. The end segment has a second waveform that includes a plurality of struts and a plurality of crowns. Each of the plurality of struts has a different length so that peaks of the crowns that define an end of the stent lie within a plane that is substantially perpendicular to the longitudinal axis. Cross-sectional areas of the struts having different lengths vary so that the struts move substantially uniformly during radial contraction and/or radial expansion of the stent.
摘要翻译：支架（10）包括具有第一波形的中心部分（12）。第一波形以间距缠绕在支架的纵向轴线上以限定多个螺旋形匝。支架还包括连接到中心部分的一端的端部段（14）。端部段具有包括多个支柱和多个冠部的第二波形。多个支柱中的每一个具有不同的长度，使得限定支架的端部的冠部的顶点位于基本上垂直于纵向轴线的平面内。具有不同长度的支柱的横截面积变化，使得支柱在支架的径向收缩和/或径向膨胀期间基本均匀地移动。

6. 发明申请

WO2009002640A1 STENT WITH IMPROVED MECHANICAL PROPERTIES 审中-公开
标题翻译：具有改进的机械性能的STENT
公开(公告)号：WO2009002640A1
公开(公告)日：2008-12-31
申请号：PCT/US2008/064250
申请日：2008-05-20
申请人： MEDTRONIC VASCULAR INC. , BIRDSALL, Matthew , PELLEGRINI, Gianfranco , GOSHGARIAN, Justin , ALLEN, Jeffrey
发明人： BIRDSALL, Matthew , PELLEGRINI, Gianfranco , GOSHGARIAN, Justin , ALLEN, Jeffrey
IPC分类号： A61F2/88 , A61F2/90
CPC分类号： A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91558 , A61F2220/0058 , A61F2250/0036
摘要： A stent (10) includes a central portion (12) having a first waveform (18). The first waveform is wrapped around a longitudinal axis (LA) of the stent at a pitch to define a plurality of helical turns (20). The stent also includes an end segment (14.16) connected to one end of the central portion. The end segment has a second waveform (32) that includes a plurality of struts (36) and a plurality of crowns (38). Each of the plurality of struts has a. different length so that peaks of the crowns that define an end of the stent. lie within a plane that is substantially perpendicular to the longitudinal axis. Cross-sectional areas of the struts having different lengths vary so that the struts move substantially uniformly during radial contraction and/or radial expansion of the stent.
摘要翻译：支架（10）包括具有第一波形（18）的中心部分（12）。第一波形以间距围绕支架的纵向轴线（LA）缠绕以限定多个螺旋形匝（20）。支架还包括连接到中心部分的一端的端部段（14.16）。端部段具有包括多个支柱（36）和多个冠部（38）的第二波形（32）。多个支柱中的每一个具有a。不同的长度使得限定支架末端的牙冠的峰值。位于基本上垂直于纵向轴线的平面内。具有不同长度的支柱的横截面积变化，使得支柱在支架的径向收缩和/或径向膨胀期间基本均匀地移动。

7. 发明申请

WO2008079557A1 STENT BALLOON ASSEMBLY AND METHOD OF MAKING SAME 审中-公开
标题翻译： STENT BALLOON ASSEMBY AND METHOD OF MAKING SAME
公开(公告)号：WO2008079557A1
公开(公告)日：2008-07-03
申请号：PCT/US2007/085123
申请日：2007-11-19
申请人： MEDTRONIC VASCULAR INC. , GOSHGARIAN, Justin
发明人： GOSHGARIAN, Justin
IPC分类号： B29D23/00 , B29C33/40 , A61F2/84 , A61F2/06 , B29C49/20
CPC分类号： B29C33/42 , A61F2/958 , A61F2002/9505 , A61F2002/9522 , A61F2002/9583 , B29C49/04 , B29C49/08 , B29K2909/08 , B29L2031/7542
摘要： A method of manufacturing a stent balloon assembly includes molding a thin section in a frusto-conical portion of a balloon, and placing a stent over a stent engaging portion of the balloon when the balloon is in an unexpanded configuration. The stent engaging portion extends from the frusto-conical portion. The method also includes heating the balloon to a temperature above the glass transition temperature of the balloon, and pressurizing the balloon while the temperature is above the glass transition temperature to create a pillow from the thin section of the frusto-conical portion. The pillow protrudes outwardly relative to the stent to prevent the stent from moving in an axial position relative to the balloon.
摘要翻译：制造支架气囊组件的方法包括：当球囊处于未膨胀构型时，在气囊的截头圆锥形部分中模制薄截面并将支架放置在球囊的支架接合部分上。支架接合部分从截头圆锥形部分延伸。该方法还包括将球囊加热到高于球囊的玻璃化转变温度的温度，并且在温度高于玻璃化转变温度时对球囊加压，以从截头圆锥形部分的薄部分产生枕头。枕头相对于支架向外突出，以防止支架相对于气囊在轴向位置移动。

8. 发明申请

WO2011034797A1 HELICAL STENT WITH CONNECTIONS 审中-公开
标题翻译：有连接的连线
公开(公告)号：WO2011034797A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/048500
申请日：2010-09-10
申请人： MEDTRONIC VASCULAR INC. , BALDWIN, Matthew , BLISS, Richard , GOSHGARIAN, Justin , HOFF, Mark , LAM, Rui
发明人： BALDWIN, Matthew , BLISS, Richard , GOSHGARIAN, Justin , HOFF, Mark , LAM, Rui
IPC分类号： A61F2/88
CPC分类号： A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91558
摘要： A stent (10) includes a continuous wave form (20) wrapped around a longitudinal axis (LA) of the stent at a first pitch angle to define a first helix comprising a plurality of turns (22). The wave form includes a plurality of struts and a plurality of crowns. Each crown connects adjacent struts within a turn to define the continuous wave form. The stent also includes a plurality of connections (30) configured to connect selected crowns of adjacent turns so that when the stent is in an unexpanded condition, the plurality of connections are aligned at a second pitch angle to define a second helix, and when the stent is in an expanded condition, at least some of the connections align along a substantially straight line parallel to the longitudinal axis of the stent.
摘要翻译：支架（10）包括围绕支架的纵向轴线（LA）缠绕的第一螺距角的连续波形（20），以限定包括多个匝（22）的第一螺旋。波形包括多个支柱和多个冠。每个表冠在一个转弯内连接相邻的支柱，以定义连续波形。支架还包括多个连接件（30），其构造成连接相邻匝的所选冠部，使得当支架处于未膨胀状态时，多个连接件以第二倾斜角对准以限定第二螺旋，并且当支架处于膨胀状态，至少一些连接件沿着平行于支架的纵向轴线的基本直线排列。

9. 发明申请

WO2011034796A1 STENT WITH IMPROVED FLEXIBILITY 审中-公开
标题翻译：具有改进灵活性的STENT
公开(公告)号：WO2011034796A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/048494
申请日：2010-09-10
申请人： MEDTRONIC VASCULAR INC. , BALDWIN, Matthew , BLISS, Richard , GOSHGARIAN, Justin , GRISWOLD, Erik , LAM, Rui
发明人： BALDWIN, Matthew , BLISS, Richard , GOSHGARIAN, Justin , GRISWOLD, Erik , LAM, Rui
IPC分类号： A61F2/88
CPC分类号： A61F2/88 , A61F2/915 , A61F2002/91508
摘要： A stent (10) includes a continuous wave form wrapped around a longitudinal axis of the stent at a pitch to define a helix comprising a plurality of turns (20). The wave form includes a plurality of struts (22) and a plurality of crowns (24). Each crown connects adjacent struts within a turn to define the continuous wave form. The stent also includes a plurality of connections configured to connect selected crowns of adjacent turns. Unconnected crowns of adjacent turns that substantially face each other are spaced from each other and define a gap therebetween. The gap between the unconnected crowns of adjacent turns is variable around a circumference of the stent.
摘要翻译：支架（10）包括以间距缠绕在支架的纵向轴线上的连续波形，以限定包括多个匝（20）的螺旋。波形包括多个支柱（22）和多个冠部（24）。每个冠在一圈内连接相邻的支柱，以定义连续波形。支架还包括多个连接，其被配置为连接相邻匝的所选冠。基本上彼此面对的相邻匝的未连接的冠彼此间隔开并且在它们之间形成间隙。相邻匝的未连接冠之间的间隙可围绕支架的圆周变化。

10. 发明申请

WO2011034794A1 METHODS FOR FORMING AN ORTHOGONAL END ON A HELICAL STENT 审中-公开
标题翻译：用于在螺旋形式上形成正交端的方法
公开(公告)号：WO2011034794A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/048485
申请日：2010-09-10
申请人： MEDTRONIC VASCULAR INC. , BLISS, Richard , GOSHGARIAN, Justin , LAM, Rui , SAVAGE, Padraig , GRISWOLD, Erik , PELLEGRINI, Gianfranco , BALDWIN, Matthew , ENSIGN, Lance
发明人： BLISS, Richard , GOSHGARIAN, Justin , LAM, Rui , SAVAGE, Padraig , GRISWOLD, Erik , PELLEGRINI, Gianfranco , BALDWIN, Matthew , ENSIGN, Lance
IPC分类号： A61F2/88
CPC分类号： A61F2/88 , A61F2/915 , A61F2002/91525 , A61F2002/91558
摘要： A method of manufacturing a stent (10) includes forming a wave form (20) having a plurality of struts (30) and a plurality of crowns (32). Each crown connects two adjacent struts. The wave form has a central portion (24) and two end portions (26, 28) located on opposite sides the central portion. Some of the struts located in the end portions have lengths longer and/or shorter than an average length of all of the struts of the wave form. The method includes wrapping the wave form about a longitudinal axis (LA) to define a plurality of turns (22) so that an end turn is oriented at an angle relative to the longitudinal axis, a second turn is at a first pitch angle that is less than the angle that the end turn is disposed relative to the longitudinal axis, a third turn is at a second pitch angle that is less than the first pitch angle, and a fourth turn is at a third pitch angle that is less than the second pitch angle.
摘要翻译：制造支架（10）的方法包括形成具有多个支柱（30）和多个牙冠（32）的波浪形（20）。每个皇冠连接两个相邻的支柱。波形具有中心部分（24）和位于中心部分的相对侧上的两个端部部分（26,28）。位于端部中的一些支柱具有比波形的所有支柱的平均长度更长和/或更短的长度。该方法包括围绕纵向轴线（LA）缠绕波形以限定多个匝（22），使得端部匝相对于纵向轴线成一角度，第二匝处于第一倾斜角小于相对于纵向轴线设置端部转向的角度，第三匝处于小于第一俯仰角的第二俯仰角，并且第四匝处于小于第二倾斜角的第三俯仰角俯仰角。

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