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1. 发明申请

WO2003092792A2 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 审中-公开
标题翻译：联合抗惊厥药（ATP）和高电压治疗心室性心律失常
公开(公告)号：WO2003092792A2
公开(公告)日：2003-11-13
申请号：PCT/US2003/007373
申请日：2003-03-10
申请人： MEDTRONIC, INC.
发明人： OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , DEGROOT, Paul, J. , SHARMA, Vinod , KASZAS, Cameron, J. , KRAUSE, Paul, G. , OLSON, Walter, H.
IPC分类号： A61N
CPC分类号： A61N1/3962 , A61N1/3987
摘要： The present invention provides a system and method for treating an arrhythmia of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time of delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.
摘要翻译：本发明提供了用于治疗心脏心律失常的系统和方法。该系统和方法包括向心脏递送抗起搏起搏（ATP）脉冲，可能之后传送高压电击。控制ATP递送，使得任何高压休克的递送时间不受先前递送ATP脉冲的影响。系统控制可以使用一个或多个可编程参数来实现，其可以包括用户指定的冲击能量。

2. 发明授权

EP1418982B1 APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：一种用于控制高电压和antitachycardic起搏治疗应用程序在可植入医疗装置
公开(公告)号：EP1418982B1
公开(公告)日：2012-12-19
申请号：EP02763358.5
申请日：2002-07-25
申请人： Medtronic, Inc.
发明人： DEGROOT, Paul, J. , OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , KRAUSE, Paul, G. , SHARMA, Vinod
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3688 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3987

3. 发明授权

EP1515778B1 APPARATUS FOR PREVENTION OF ARRHYTHMIA CLUSTERS USING OVERDRIVE PACING 有权
标题翻译：装置，以防止心律失常集群使用超速脉冲
公开(公告)号：EP1515778B1
公开(公告)日：2008-02-20
申请号：EP03760405.5
申请日：2003-06-13
申请人： MEDTRONIC, INC.
发明人： PADMANABHAN, Vasant , OLSON, Walter, H. , MEHRA, Rahul , ZHOU, Xiaohong , MULLEN, Thomas, J. , GEORGE, William, J.
IPC分类号： A61N1/37
CPC分类号： A61N1/3622
摘要： An implantable medical device that includes a microprocessor that characterizes cardiac activity of apatient to enable the implantable medical device to deliver therapy in response to an identified arrhythmia event. A monitor/controller monitors the characterized cardiac activity and the delivered therapy, and controls activation of triggered overdrive pacing subsequent to the delivered therapy.

4. 发明申请

WO2003092792A3 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 审中-公开
公开(公告)号：WO2003092792A3
公开(公告)日：2003-11-13
申请号：PCT/US2003/007373
申请日：2003-03-10
申请人： MEDTRONIC, INC.
发明人： OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , DEGROOT, Paul, J. , SHARMA, Vinod , KASZAS, Cameron, J. , KRAUSE, Paul, G. , OLSON, Walter, H.
IPC分类号： A61N1/39
摘要： The present invention provides a system and method for treating an arrhythmia of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time of delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.

5. 发明申请

WO2003011391A3 METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
公开(公告)号：WO2003011391A3
公开(公告)日：2003-02-13
申请号：PCT/US2002/023779
申请日：2002-07-25
申请人： MEDTRONIC, INC.
发明人： DEGROOT, Paul, J. , OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , KRAUSE, Paul, G. , SHARMA, Vinod
IPC分类号： A61N1/362
摘要： A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP during Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the ATP therapy is delivered prior to charging of the high-voltage capacitor. According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP therapy.

6. 发明申请

WO2004112896A1 AUTOMATIC EGM AMPLITUDE MEASUREMENTS DURING TACHYARRHYTHMIA EPISODES 审中-公开
标题翻译： TACHYARHYTHMIA EPISODES期间的自动EGM幅度测量
公开(公告)号：WO2004112896A1
公开(公告)日：2004-12-29
申请号：PCT/US2004/019486
申请日：2004-06-18
申请人： MEDTRONIC, INC. , BRANDSTETTER, John, S. , PADMANABHAN, Vasant
发明人： BRANDSTETTER, John, S. , PADMANABHAN, Vasant
IPC分类号： A61N1/362
CPC分类号： A61N1/3704 , A61B5/0456 , A61B5/0464 , A61N1/3621
摘要： In an IMD (10), when tachyarrhythmia detection criterion are satisfied or a high intrinsic heart rate is detected, a peak amplitude detection circuit (186) is enabled to detect the peak amplitude of the cardiac signal of interest, i.e., the P-wave in the case of atrial tachyarrhythmias and the R-wave in case of ventricular tachyarrhythmias. Peak amplitude data is accumulated for subsequent use in setting sensing thresholds and/or gain of a sense amplifier (128) to reduce undersensing of lower amplitude cardiac signals during such tachyarrhythmias.
摘要翻译：在IMD（10）中，当满足快速心律失常检测标准或检测到高内在心率时，可使峰值振幅检测电路（186）检测感兴趣心脏信号的峰值振幅，即P波在房性快速性心律失常的情况下和在室性快速性心律失常的情况下的R波。累积峰值幅度数据用于随后用于设置感测阈值和/或读出放大器（128）的增益，以减少在这种快速性心律失常期间较低振幅心脏信号的不足的感觉。

7. 发明申请

WO2003105953A1 METHOD AND APPARATUS FOR PREVENTION OF ARRHYTHMIA CLUSTERS USING OVERDRIVE PACING 审中-公开
标题翻译：用于防止使用过度喷雾的ARRHYTHMIA聚类的方法和装置
公开(公告)号：WO2003105953A1
公开(公告)日：2003-12-24
申请号：PCT/US2003/018986
申请日：2003-06-13
申请人： MEDTRONIC, INC.
发明人： PADMANABHAN, Vasant , CAMP, Walter, H. , MEHRA, Rahul , ZHOU, Xiaohong , MULLEN, Thomas, J. , GEORGE, William, J.
IPC分类号： A61N1/37
CPC分类号： A61N1/3622
摘要： An implantable medical device that includes a microprocessor that characterizes cardiac activity of apatient to enable the implantable medical device to deliver therapy in response to an identified arrhythmia event. A monitor/controller monitors the characterized cardiac activity and the delivered therapy, and controls activation of triggered overdrive pacing subsequent to the delivered therapy.
摘要翻译：一种可植入医疗装置，其包括表征心脏的心脏活动的微处理器，以使可植入医疗装置响应于所识别的心律失常事件递送治疗。监视器/控制器监视所表征的心脏活动和递送的治疗，并且在递送治疗之后控制触发的超速起搏起搏。

8. 发明申请

WO2003011391A2 METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于控制在可植入医疗装置中提供高电压和抗紫外线治疗的方法和装置
公开(公告)号：WO2003011391A2
公开(公告)日：2003-02-13
申请号：PCT/US2002/023779
申请日：2002-07-25
申请人： MEDTRONIC, INC.
发明人： DEGROOT, Paul, J. , OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , KRAUSE, Paul, G. , SHARMA, Vinod
IPC分类号： A61N
CPC分类号： A61N1/3622 , A61N1/3688 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3987
摘要： A system and method for delivering both anti-tachy pacing (ATP) _therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP During Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP Before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the ATP therapy is delivered prior to charging of the high-voltage capacitor. According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP therapy.
摘要翻译：公开了一种用于响应于异常心律的检测而提供抗起搏起搏（ATP）治疗和高压休克疗法的系统和方法。该系统基于预定的一组标准来控制ATP治疗与高压电容器的充电之间的时间，以准备冲击输送。在一个实施例中，本发明的系统在ATP电容器充电（ATP-DCC）模式中工作，其中在高压电容器的充电期间全部或基本上全部ATP治疗被递送。基于对预定标准集合的评估，系统可以切换到在电容器充电（ATP-BCC）模式之外的另外的ATP，其中在高压电容器充电之前基本上全部ATP治疗被递送。根据本发明的一个方面，预定的一组标准至少部分地基于先前传递的ATP治疗的有效性。

9. 发明授权

EP1501600B1 COMBINED ANTI-TACHYCARDIA PACING (ATP) AND HIGH VOLTAGE THERAPY FOR TREATING VENTRICULAR ARRHYTHMIAS 有权
标题翻译：联合抗心动过速 - PACE和高压治疗室性心律失常的治疗
公开(公告)号：EP1501600B1
公开(公告)日：2009-05-13
申请号：EP03747564.7
申请日：2003-03-10
申请人： MEDTRONIC, INC.
发明人： OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , DEGROOT, Paul, J. , SHARMA, Vinod , KASZAS, Cameron, J. , KRAUSE, Paul, G. , OLSON, Walter, H.
IPC分类号： A61N1/39
CPC分类号： A61N1/3962 , A61N1/3987
摘要： The present invention provides a system and method for treating an arrhythmia of the heart. The system and method involves delivery of anti-tachy pacing (ATP) pulses to the heart, possibly followed by the delivery of a high-voltage shock. ATP delivery is controlled such that the time of delivery of any high-voltage shock is not affected by the prior delivery of the ATP pulses. System control may be accomplished using one or more programmable parameters, which may include a user-specified shock energy.

10. 发明公开

EP1418982A2 METHOD AND APPARATUS TO CONTROL DELIVERY OF HIGH-VOLTAGE AND ANTI-TACHY PACING THERAPY IN AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：一种用于控制高电压和antitachycardic起搏治疗应用程序在可植入医疗装置
公开(公告)号：EP1418982A2
公开(公告)日：2004-05-19
申请号：EP02763358.5
申请日：2002-07-25
申请人： Medtronic, Inc.
发明人： DEGROOT, Paul, J. , OUSDIGIAN, Kevin, T. , PADMANABHAN, Vasant , KRAUSE, Paul, G. , SHARMA, Vinod
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3688 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3987
摘要： A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage capacitors in preparation for shock delivery based on a predetermined set of criteria. In one embodiment, the inventive system operates in an ATP during Capacitor Charging (ATP-DCC) mode wherein all, or substantially all, of the ATP therapy is delivered during charging of the high-voltage capacitors. Based on evaluation of the predetermined set of criteria, the system may switch to an additional ATP before Capacitor Charging (ATP-BCC) mode, wherein substantially all of the ATP therapy is delivered prior to charging of the high-voltage capacitor. According to one aspect of the invention, the predetermined set of criteria is based, at least in part, on the effectiveness of previously-delivered ATP therapy.

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