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1. 发明申请

WO2021175992A1 SYSTEM AND METHOD FOR INTERACTIVE CONTOURING OF MEDICAL IMAGES 审中-公开
公开(公告)号：WO2021175992A1
公开(公告)日：2021-09-10
申请号：PCT/EP2021/055462
申请日：2021-03-04
申请人： MIRADA MEDICAL LIMITED , GOODING, Mark , BOUKERROUI, Djamal , TRIMPL, Michael Johann
发明人： GOODING, Mark , BOUKERROUI, Djamal , TRIMPL, Michael Johann
IPC分类号： G06T7/13 , G06T7/174
摘要： A method and imaging system for contouring medical images is described. The method comprising: receiving at least one input 2D image slice, from a set of two-dimensional (2D) image slices constituting the 3D image, and at least one set of data representing an input contour identifying one or more structures of interest in the 3D image within the at least one input 2D image slice; receiving at least one selected target image slice, from the set of the 2D image slices; and predicting target contour data for the selected target image slice that identifies at least one of the same one or more structures of interest within the target image slice, based on one or more of the received input 2D image slices and the data representing an input contours.

2. 发明申请

WO2020078725A1 SYSTEM AND METHOD FOR AUTOMATIC DELINEATION OF SCANNED IMAGES 审中-公开
公开(公告)号：WO2020078725A1
公开(公告)日：2020-04-23
申请号：PCT/EP2019/076743
申请日：2019-10-02
申请人： MIRADA MEDICAL LIMITED , GOODING, Mark , BOUKERROUI, Djamal , BALFOUR, Daniel
发明人： GOODING, Mark , BOUKERROUI, Djamal , BALFOUR, Daniel
IPC分类号： G06T7/12
摘要： A method and imaging system for generating synthetic scan images for use in a database of image and contour pairs is described. The database is used in the delineation of features in one or more real scan images, and the method comprising the steps of: providing a delineated real scan image acquired using a first image scanner defining a model related to the generation of a synthetic scan image using a second image scanner, processing the delineated real scan image using the model to generate said synthetic scan image, and mapping contours from the delineated real image to the synthetic image to form a new synthetic image-contour pair; repeating said providing, defining and processing steps for a plurality of delineated real scan images to generate a corresponding plurality of synthetic scan images and contour pairs for the database of image and contour pairs; using said database of generated plurality of synthetic scan images and contour pairs to optimise an automated contouring algorithm, where the optimised algorithm generates contours for the real scan images of the same type as the synthetic scan images; processing one or more further real scan images of the same type as said synthetic scan images to contour and delineate features on said further real scan image using said optimised automated contouring algorithm.

3. 发明申请

WO2012136669A2 MEASUREMENT SYSTEM FOR MEDICAL IMAGES 审中-公开
标题翻译：医学图像测量系统
公开(公告)号：WO2012136669A2
公开(公告)日：2012-10-11
申请号：PCT/EP2012/056098
申请日：2012-04-03
申请人： MIRADA MEDICAL LIMITED , KADIR, Timor , GOODING, Mark
发明人： KADIR, Timor , GOODING, Mark
IPC分类号： G06T7/00 , G06T7/60 , A61B6/00 , A61B8/00
CPC分类号： G06T7/0012 , A61B6/463 , A61B6/467 , A61B8/461 , A61B8/467 , A61B8/469 , G06T7/50 , G06T7/60 , G06T19/00 , G06T2207/20101 , G06T2207/30096 , G06T2210/41
摘要： A method of measuring a parameter of a structure (212) on a medical image (200) comprises a measurement tool (220) displayed on a slice of the image. An automated point detection function identifies a point within at least one region (250) of the image that optimises the placement of the respective end of the measurement tool (220). The region may be 2-d or 3-d. The identified point(s) are then used to calculate the parameter, which may be distance, angle, area or volume. The measurement tool (320) may move to the identified points (330, 340). A system (2000), computer program and computer-readable medium are also provided. The invention may make the measurement of tumours, and measurements of the spacing within or between various structures on a medical image, more accurate and/or more consistent.
摘要翻译：测量医学图像（200）上的结构（212）的参数的方法包括显示在图像的切片上的测量工具（220）。自动点检测功能识别图像的至少一个区域（250）内的点，其优化测量工具（220）的相应末端的位置。该区域可以是2-d或3-d。然后使用所识别的点来计算参数，其可以是距离，角度，面积或体积。测量工具（320）可以移动到所识别的点（330,340）。还提供了系统（2000），计算机程序和计算机可读介质。本发明可以进行肿瘤的测量，以及医学图像上各种结构之间或之间的间隔的测量，更准确和/或更一致。

4. 发明申请

WO2016198568A1 SELECTION OF A SUBSET OF ATLASES FROM A SET OF CANDIDATE ATLASES 审中-公开
标题翻译：从一组候选人选中选择一个座位
公开(公告)号：WO2016198568A1
公开(公告)日：2016-12-15
申请号：PCT/EP2016/063248
申请日：2016-06-10
申请人： MIRADA MEDICAL LIMITED , GOODING, Mark , KADIR, Timor , LARRUE, Aymeric
发明人： GOODING, Mark , KADIR, Timor , LARRUE, Aymeric
IPC分类号： G06T7/00
CPC分类号： G06T7/12 , G06T7/174 , G06T2207/10072 , G06T2207/10081 , G06T2207/20081 , G06T2207/20128 , G06T2207/30004
摘要： A method and apparatus for selecting a subset of atlases from a set of candidate atlases. The method comprises: for each candidate atlas n within the set of N candidate atlases, computing an auto-contouring performance measure in relation to each training atlas t within a subset of a set of T training atlases; for each pair combination of candidate atlas n and training atlas t for which an auto-contouring performance measure has been computed, deriving a score based on the computed auto-contouring performance measures; for each candidate atlas n within the set of N candidate atlases, aggregating the derived scores for each pair combination comprising that candidate atlas n; and selecting a subset of M candidate atlases from the set of N candidate atlases based on the aggregated scores therefor.
摘要翻译：一种用于从一组候选地图集中选择地图集的子集的方法和装置。该方法包括：对于N个候选地图集的集合内的每个候选地图集，计算与一组T训练地图集的子集内的每个训练图集t相关的自动轮廓性能测量; 对于候选图集n的每一对组合和已经计算出自动轮廓性能测量的训练图谱t，基于所计算的自动轮廓性能测量得出分数; 对于N个候选图集的集合内的每个候选图集n，聚合包含该候选图集n的每个对组合的导出得分; 并根据其聚合分数从该N个候选地图集的集合中选择M个候选地图集的子集。

5. 发明申请

WO2022018237A1 SYSTEM AND METHOD FOR TIME-SERIES IMAGING 审中-公开
公开(公告)号：WO2022018237A1
公开(公告)日：2022-01-27
申请号：PCT/EP2021/070621
申请日：2021-07-22
申请人： MIRADA MEDICAL LIMITED , VAN HERK, Marcel , MCWILLIAM, Alan , BANFILL, Kathryn , FAIVRE-FINN, Corinne , GOODING, Mark , BOUKERROUI, Djamal
发明人： VAN HERK, Marcel , MCWILLIAM, Alan , BANFILL, Kathryn , FAIVRE-FINN, Corinne , GOODING, Mark , BOUKERROUI, Djamal
IPC分类号： G06T7/30
摘要： A method and imaging system for creating a motion compensated 3D volumetric derived image from a 4D volumetric medical image is described. The method comprising the steps of: acquiring a 4D volumetric medical image comprising a plurality of 3D volumetric medical images forming a time-series of 3D volumetric medical images representing phases of a physiological motion cycle; determining dominant motion of each 3D volumetric medical image with respect to a reference location that represents a position relative to the motion cycle; resampling each of the 3D volumetric medical images to the reference location to compensate for the determined dominant motion; estimating secondary motion in at least one of each motion compensated 3D volumetric medical images or of each of the original 3D volumetric medical images; and constructing a 3D volumetric derived image by combining data from the motion compensated 3D volumetric images based on the estimated secondary motion.

6. 发明申请

WO2016142166A1 METHOD AND APPARATUS FOR ASSESSING IMAGE REGISTRATION 审中-公开
标题翻译：用于评估图像注册的方法和装置
公开(公告)号：WO2016142166A1
公开(公告)日：2016-09-15
申请号：PCT/EP2016/053714
申请日：2016-02-23
申请人： MIRADA MEDICAL LIMITED , GOODING, Mark , KADIR, Timor
发明人： GOODING, Mark , KADIR, Timor
IPC分类号： G06T7/00
CPC分类号： G06T7/30 , G06T2207/30004
摘要： A method and apparatus for assessing image registration. The method comprises obtaining image datasets for the first and second medical images and registration data representing the registration from the first medical image to the second medical image, collating use-case information for the image registration, deriving a set of at least one measurement and assessment criteria therefor based at least partly on the collated use-case information, performing the at least one measurement on at least one of the obtained image datasets and the obtained registration data to derive at least one measurement value, applying the assessment criteria for the at least one measurement to the at least one measurement value to derive at least one assessment result, and outputting an indication of the at least one assessment result.
摘要翻译：一种用于评估图像配准的方法和装置。该方法包括：获取第一和第二医学图像的图像数据集，以及表示从第一医学图像到第二医学图像的登记的登记数据，整理用于图像配准的用例信息，导出至少一个测量和评估的集合至少部分地基于整理的用例信息，对所获得的图像数据集和所获得的注册数据中的至少一个进行至少一个测量以导出至少一个测量值，对至少一个测量值应用评估标准对所述至少一个测量值进行一次测量以得到至少一个评估结果，以及输出所述至少一个评估结果的指示。

7. 发明申请

WO2016016227A1 METHOD AND APPARATUS FOR DELINEATING AN OBJECT WITHIN A VOLUMETRIC MEDICAL IMAGE 审中-公开
标题翻译：用于在体外医学图像中分类对象的方法和装置
公开(公告)号：WO2016016227A1
公开(公告)日：2016-02-04
申请号：PCT/EP2015/067244
申请日：2015-07-28
申请人： MIRADA MEDICAL LIMITED , GOODING, Mark , KADIR, Timor , LARRUE, Aymeric
发明人： GOODING, Mark , KADIR, Timor , LARRUE, Aymeric
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/12 , G06T7/60 , G06T2207/20096 , G06T2207/20104 , G06T2207/20108 , G06T2207/20128 , G06T2207/30004
摘要： A method and apparatus for delineating an object within a volumetric medical image. The method comprises obtaining auto-generated contour data for the object within the volumetric medical image, the auto-generated contour data defining a set of auto-generated contours forming a delineation structure for the object, selecting a subset of auto-generated contours for manual editing, and identifying the selected subset of auto-generated contours to a user. In some examples, the method further comprises presenting at least the selected subset of auto-generated contours to the user, receiving user feedback for at least one auto-generated contour, deriving a full set of contours forming a revised delineation structure for the object based at least partly on an interpolation of the auto-generated contour(s) for which user feedback was received, and storing contour data defining the derived full set of contours forming the revised delineation structure for the object within at least one data storage device.
摘要翻译：一种用于描绘体积医学图像内的物体的方法和装置。该方法包括获取体积医学图像内的对象的自动生成轮廓数据，自动生成的轮廓数据定义一组自动生成轮廓，形成对象的描绘结构，选择自动生成轮廓的子集以进行手动编辑和识别所选择的自动生成轮廓的子集给用户。在一些示例中，该方法还包括向用户呈现至少所选择的自动生成轮廓的子集，接收至少一个自动生成的轮廓的用户反馈，导出形成用于基于对象的修订的描绘结构的全套轮廓至少部分地基于对于其接收到用户反馈的自动生成轮廓的内插，以及存储定义所导出的全套轮廓的轮廓数据，所述轮廓对于所述对象在至少一个数据存储装置中形成修订的描绘结构。

8. 发明申请

WO2014206722A1 METHOD AND APPARATUS FOR GENERATING IMAGE ALIGNMENT DATA 审中-公开
标题翻译：用于生成图像对齐数据的方法和装置
公开(公告)号：WO2014206722A1
公开(公告)日：2014-12-31
申请号：PCT/EP2014/062040
申请日：2014-06-10
申请人： MIRADA MEDICAL LIMITED
发明人： KADIR, Timor , GOODING, Mark , BROWN, Ian
IPC分类号： G06T7/00
CPC分类号： G06T7/0028 , G06T7/30 , G06T7/33 , G06T7/38 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/20072 , G06T2207/30004 , G06T2210/41
摘要： A method of generating image alignment data for medical images. The method comprises determining prospective image pair registration connections, determining registration weighting values for the determined prospective image pair registration connections based at least partly on intra-image attribute data, determining optimal registration paths for image pairs based at least partly on the registration weighting values for the prospective image pair registration connections, and generating image alignment data for the determined optimal registration paths.
摘要翻译：一种生成医学图像的图像对准数据的方法。该方法包括：确定预期图像对注册连接，至少部分地基于图像内属性数据确定所确定的预期图像对注册连接的注册加权值，至少部分地基于注册加权值来确定图像对的最佳注册路径，预期图像对注册连接，以及为所确定的最佳注册路径生成图像对准数据。

9. 发明公开

EP2695138A2 MEASUREMENT SYSTEM FOR MEDICAL IMAGES 有权
标题翻译： MESSSYSTEMFÜRMEDISINISCHE BILDER
公开(公告)号：EP2695138A2
公开(公告)日：2014-02-12
申请号：EP12716295.6
申请日：2012-04-03
申请人： Mirada Medical Limited
发明人： KADIR, Timor , GOODING, Mark
IPC分类号： G06T7/00 , G06T7/60 , A61B6/00 , A61B8/00
CPC分类号： G06T7/0012 , A61B6/463 , A61B6/467 , A61B8/461 , A61B8/467 , A61B8/469 , G06T7/50 , G06T7/60 , G06T19/00 , G06T2207/20101 , G06T2207/30096 , G06T2210/41
摘要： A method of measuring a parameter of a structure (212) on a medical image (200) comprises a measurement tool (220) displayed on a slice of the image. An automated point detection function identifies a point within at least one region (250) of the image that optimizes the placement of the respective end of the measurement tool (220). The region may be 2-d or 3-d. The identified point(s) are then used to calculate the parameter, which may be distance, angle, area or volume. The measurement tool (320) may move to the identified points (330, 340). A system (2000), computer program and computer-readable medium are also provided. The invention may make the measurement of tumors, and measurements of the spacing within or between various structures on a medical image, more accurate and/or more consistent.
摘要翻译：测量医学图像（200）上的结构（212）的参数的方法包括显示在图像的切片上的测量工具（220）。自动点检测功能识别图像的至少一个区域（250）内的点，其优化测量工具（220）的相应末端的位置。该区域可以是2-d或3-d。然后使用识别的点来计算参数，其可以是距离，角度，面积或体积。测量工具（320）可以移动到所识别的点（330,340）。还提供了系统（2000），计算机程序和计算机可读介质。本发明可以进行肿瘤的测量，以及医学图像上各种结构之间或之间的间隔的测量，更准确和/或更一致。

10. 发明公开

EP4100915A1 SYSTEM AND METHOD FOR INTERACTIVE CONTOURING OF MEDICAL IMAGES 审中-实审
公开(公告)号：EP4100915A1
公开(公告)日：2022-12-14
申请号：EP21708678.4
申请日：2021-03-04
申请人： Mirada Medical Limited
发明人： GOODING, Mark , BOUKERROUI, Djamal , TRIMPL, Michael Johann
IPC分类号： G06T7/13 , G06T7/174

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