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    • 4. 发明申请
    • DETECTION OF ANISOTROPIC BIOLOGICAL TISSUE
    • 检测各向异性生物组织
    • WO2016166067A1
    • 2016-10-20
    • PCT/EP2016/057948
    • 2016-04-12
    • KONINKLIJKE PHILIPS N.V.
    • MUELLER, ManfredHENDRIKS, Bernardus Hendrikus WilhelmusLUCASSEN, Gerhardus WilhelmusBYDLON, Torre Michelle
    • A61B5/00
    • A61B5/4893A61B5/0075A61B5/0082
    • A system for detection of optically anisotropic tissue is provided. The system comprises an optical source, an optical detector, a processing unit and a probe. The probe has a shaft with a longitudinal axis and a front end, and a plurality of optical fibers; wherein an end of each of the optical fibers is arranged at the front end of the shaft, and at least one of the optical fibers is a source optical fiber adapted to transmit optical radiation emitted from the optical source to a tissue adjacent to the front end of the shaft. Another one of the optical fibers is a detector optical fiber adapted to transmit optical radiation reflected from the tissue to the optical detector, so that an optical path through the tissue is defined, wherein the optical paths differ from each other with respect to their spatial orientation, and wherein the optical paths cross each other. The processor is configured to control the optical source to emit optical radiation, to receive a signal generated by the optical detector based on the optical radiation reflected by the tissue, to determine a plurality of optical spectra of the reflected optical radiation based on the received signal, wherein the optical spectra are obtained of the same location from at least two different directions, wherein the measurement of the optical spectra is performed either simultaneously or sequentially, and to compare the plurality of optical spectra, wherein the optical spectra relate to optical radiation of the different optical paths thus allowing the detection of anisotropic tissue using differences between the optical spectra.
    • 提供了一种光学各向异性组织检测系统。 该系统包括光源,光学检测器,处理单元和探针。 探针具有纵轴和前端的轴和多根光纤; 其中每个光纤的端部被布置在所述轴的前端,并且所述光纤中的至少一个是源光学光纤,其适于将从所述光源发射的光辐射传输到邻近所述前端的组织 的轴。 另一种光纤是适于将从组织反射的光辐射传输到光学检测器的检测器光纤,从而限定通过组织的光路,其中光路相对于它们的空间取向彼此不同 ,并且其中所述光路彼此交叉。 处理器被配置为控制光源发射光辐射,以基于由组织反射的光辐射接收由光学检测器产生的信号,以基于接收信号确定反射的光辐射的多个光谱 ,其中从至少两个不同方向获得相同位置的光谱,其中光谱的测量同时或顺序地进行,并且比较多个光谱,其中光谱涉及光谱的光辐射 不同的光路因此允许使用光谱之间的差异来检测各向异性组织。