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    • 8. 发明申请
    • BIOSENSOR WITH ONE-DIMENSIONAL SUB-DIFFRACTION-LIMITED APERTURES COMPOSED OF A GRID AND A POLARIZER
    • 具有一维分散衍射的生物传感器 - 由网格和极化器组成的有限成分
    • WO2007072293A3
    • 2007-10-18
    • PCT/IB2006054750
    • 2006-12-11
    • KONINKL PHILIPS ELECTRONICS NVPHILIPS CORPVAN HERPEN MAARTENBROER DIRK JPEETERS EMIELKLUNDER DERK J WSTAPERT HENDRIK R
    • VAN HERPEN MAARTENBROER DIRK JPEETERS EMIELKLUNDER DERK J WSTAPERT HENDRIK R
    • G01N21/63
    • G01N21/648Y10T436/11
    • A method and sensor for the detection of luminescence radiation generated by at least one luminophore is disclosed. In the context of the present invention the biosensor comprises a grid (120) defined as arrays of apertures with the apertures having a first dimension below and a second dimension above the diffraction limit of the excitation light (102) in a medium, a polarizer (115), and luminophores (117) positioned in a volume selected from the group consisting of: the volume inside the apertures of the grid (120), the volume in between the array of slits (120) and the polarizer (115) and a volume that extends into the polarizer (115), wherein the grid (120) providing a transmission axis extending in a first direction and the polarizer (115) providing a transmission axis extending in a second direction, the first direction and the second direction being substantially perpendicular with respect to each other, wherein the excitation radiation (102) is polarized such that it is substantially suppressed by one of the at least one grid (120) and polarizer (115) and substantially not suppressed by the other of the at least one grid (120) and polarizer (115).
    • 公开了一种用于检测由至少一个发光体产生的发光辐射的方法和传感器。 在本发明的上下文中,生物传感器包括定义为孔阵列的格栅(120),孔格具有第一尺寸,第二维度高于介质中的激发光(102)的衍射极限,偏振器( 115)和位于选自以下的体积中的发光体(117):栅格(120)的孔内的体积,狭缝阵列(120)和偏振器(115)之间的体积和 延伸到偏振器(115)的体积,其中提供沿第一方向延伸的透射轴的格栅(120)和提供沿第二方向延伸的透射轴的偏振器(115),第一方向和第二方向基本上 垂直于彼此垂直,其中所述激发辐射(102)被极化,使得其基本上被所述至少一个格栅(120)和偏振器(115)中的一个所抑制,并且基本上不被所述o 该至少一个格栅(120)和偏振器(115)。