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    • 1. 发明授权
    • Method for forming an electrophysiology catheter
    • 形成电生理学导管的方法
    • US5888577A
    • 1999-03-30
    • US885501
    • 1997-06-30
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • A61L29/10B05D3/00B05D5/12
    • A61L29/10
    • A catheter has an electrically conductive material coated, deposited, or otherwise formed directly on the outer surface of the catheter. Preferably, an outer electrode is formed by ion-beam assisted deposition using a preselected metal for efficient vaporization onto the designated surface region of the catheter body. Alternatively, the electrically conductive coating may be formed by sputtering the metal onto that region of the catheter, vacuum deposition, spraying, or printing the electrically conductive material onto the entire surface region. Portions of the coating may be removed by directing a laser beam onto the outer surface of the catheter and ablating such portions. The result is an electrically conductive coating of desired thickness used to form a relatively uniform electrode throughout the desired length and surface region of the catheter body to improve the characteristics of electric field and to form an electrode which flexes to substantially the same extent as the catheter body without such a coating. As a result, the electrode does not impede the flexibility of the catheter.
    • 导管具有涂覆,沉积或以其它方式直接形成在导管的外表面上的导电材料。 优选地,外电极通过使用预选金属的离子束辅助沉积形成,以便有效地蒸发到导体主体的指定表面区域上。 或者,可以通过将金属溅射到导管的该区域,真空沉积,喷涂或将导电材料印刷到整个表面区域上来形成导电涂层。 可以通过将激光束引导到导管的外表面并消融这些部分来去除涂层的部分。 结果是所需厚度的导电涂层用于在导体主体的所需长度和表面区域形成相对均匀的电极,以改善电场的特性并形成电极,其弯曲到与导管大体相同的程度 身体没有这样的涂层。 结果,电极不妨碍导管的柔性。
    • 2. 发明授权
    • Electrophysiology catheter
    • 电生理导管
    • US06173205B2
    • 2001-01-09
    • US09318026
    • 1999-05-25
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • A61N105
    • A61N1/0563
    • A defibrillation electrophysiology catheter for stimulating the heart and sensing the resulting activity of the heart for determining a patient's potential to have an arrhythmia occur under uncontrolled circumstances and for defibrillating the heart if fibrillation occurs accidentally during the testing is disclosed. The catheter is provided with electrodes formed on the distal surface of the catheter which is placed near the patient's heart. The electrodes may be placed on the catheter in a variety of configurations. An external electrode in the form of a patch or pad is placed on the patient's back. Energy is applied to the system in order to shock the heart and defibrillate the same. The procedure is less invasive than the procedures requiring the electrodes to be implanted at or near the patient's heart and chest wall and requires less energy and time than the procedures requiring the use of two external paddles.
    • 用于刺激心脏并感测心脏产生的活动的除颤电生理学导管用于确定患者具有心律不齐的可能性发生在不受控制的情况下,并且在测试期间意外发生原纤维性颤动时,使心脏去纤维化。 导管设置有形成在导管的远端表面上的电极,其放置在患者心脏附近。 电极可以以各种配置放置在导管上。 将贴片或垫片形式的外部电极放置在患者的背部。 能量被施加到系统以便震动心脏并除颤。 该过程比需要将电极植入患者心脏和胸壁处或附近的程序侵入性较小,并且比需要使用两个外部桨叶的程序需要更少的能量和时间。
    • 3. 发明授权
    • Method of defibrillating employing coronary sinus and external patch
electrodes
    • 使用冠状窦和外部贴片电极去纤颤的方法
    • US6085117A
    • 2000-07-04
    • US318027
    • 1999-05-25
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • A61N1/05A61N1/39
    • A61N1/0563
    • A defibrillation electrophysiology catheter for stimulating the heart and sensing the resulting activity of the heart for determining a patient's potential to have an arrhythmia occur under uncontrolled circumstances and for defibrillating the heart if fibrillation occurs accidentally during the testing is disclosed. The catheter is provided with electrodes formed on the distal surface of the catheter which is placed near the patient's heart. The electrodes may be placed on the catheter in a variety of configurations. An external electrode in the form of a patch or pad is placed on the patient's back. Energy is applied to the system in order to shock the heart and defibrillate the same. The procedure is less invasive than the procedures requiring the electrodes to be implanted at or near the patient's heart and chest wall and requires less energy and time than the procedures requiring the use of two external paddles.
    • 用于刺激心脏并感测心脏产生的活动的除颤电生理学导管用于确定患者具有心律不齐的可能性发生在不受控制的情况下,并且在测试期间意外发生原纤维性颤动时,使心脏去纤维化。 导管设置有形成在导管的远端表面上的电极,其放置在患者心脏附近。 电极可以以各种配置放置在导管上。 将贴片或垫片形式的外部电极放置在患者的背部。 能量被施加到系统以便震动心脏并除颤。 该过程比需要将电极植入患者心脏和胸壁处或附近的程序侵入性较小,并且比需要使用两个外部桨叶的程序需要更少的能量和时间。
    • 4. 发明授权
    • Electrophysiology catheter
    • 电生理导管
    • US5931863A
    • 1999-08-03
    • US81501
    • 1998-05-20
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • A61N1/05
    • A61N1/0563
    • A defibrillation electrophysiology catheter for stimulating the heart and sensing the resulting activity of the heart for determining a patient's potential to have an arrhythmia occur under uncontrolled circumstances and for defibrillating the heart if fibrillation occurs accidentally during the testing is disclosed. The catheter is provided with electrodes formed on the distal surface of the catheter which is placed near the patient's heart. The electrodes may be placed on the catheter in a variety of configurations. An external electrode in the form of a patch or pad is placed on the patient's back. Energy is applied to the system in order to shock the heart and defibrillate the same. The procedure is less invasive than the procedures requiring the electrodes to be implanted at or near the patient's heart and chest wall and requires less energy and time than the procedures requiring the use of two external paddles.
    • 用于刺激心脏并感测心脏产生的活动的除颤电生理学导管用于确定患者具有心律不齐的可能性发生在不受控制的情况下,并且在测试期间意外发生原纤维性颤动时,使心脏去纤维化。 导管设置有形成在导管的远端表面上的电极,其放置在患者心脏附近。 电极可以以各种配置放置在导管上。 将贴片或垫片形式的外部电极放置在患者的背部。 能量被施加到系统以便震动心脏并除颤。 该过程比需要将电极植入患者心脏和胸壁处或附近的程序侵入性较小,并且比需要使用两个外部桨叶的程序需要更少的能量和时间。
    • 5. 发明授权
    • Combined cable and electrophysiology catheters
    • 组合电缆和电生理导管
    • US5928276A
    • 1999-07-27
    • US95918
    • 1998-06-11
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • Joseph C. Griffin, IIIDavid A. Jenkins
    • A61N1/05
    • A61N1/05
    • A single-use, disposable electrophysiology catheter having an elongated flexible tube with a proximal end and a distal end and a cable permanently secured to the proximal end via a connector is disclosed. The cable has a length of approximately four feet and is in the form of a folded ribbon, encased in a perforated plastic wrap until it is ready to be used. In this manner, the cable remains sterile until it is ready to be used. When the cable is needed, the wrap is torn along the perforation by pulling on the cable. The cable also has an adapter on its proximal end which may be used to attach an extension cable if a greater length is necessary.
    • 公开了具有近端和远端的细长柔性管和经由连接器永久固定到近端的电缆的单次使用的一次性电生理导管。 电缆具有大约四英尺的长度,并且是折叠的带的形式,包裹在穿孔的塑料包装中,直到其准备使用。 以这种方式,电缆保持无菌,直到它准备使用。 当需要电缆时,通过拉扯电缆将包裹沿着穿孔撕开。 电缆还在其近端具有适配器,如果需要更长的长度,则其可以用于连接延长电缆。
    • 7. 发明授权
    • Process for the recovery of terephthalic acid and ethylene glycol from
poly(ethylene terephthalate)
    • 从聚对苯二甲酸乙二醇酯回收对苯二甲酸和乙二醇的方法
    • US5413681A
    • 1995-05-09
    • US151637
    • 1993-11-15
    • Gerald C. TustinThomas M. Pell, Jr.David A. JenkinsMary T. Jernigan
    • Gerald C. TustinThomas M. Pell, Jr.David A. JenkinsMary T. Jernigan
    • B01D3/00B01D3/14C07C51/09
    • C07C51/09B01D3/009B01D3/146C08J11/14C08J2367/02Y02P20/127Y02W30/704Y10S203/13Y10S203/17
    • A process useful for the recovery of terephthalic acid and ethylene glycol from poly(ethylene terephthalate) or its copolymers. The process is economical, beneficial to the environment and provides polymer grade terephthalic acid and ethylene glycol from post-consumer resin. The process is a six-step process including: (1) contacting a resin containing poly(ethylene terephthalate) with water at elevated temperature and pressure, (2) cooling the resulting mixture to provide a solid portion containing terephthalic acid and a liquid portion containing ethylene glycol, (3) recovery of the ethylene glycol from the liquid portion by distillation, (4) recovery of the terephthalic acid by heating the solid portion in the presence of water vapor at elevated temperature to produce a vapor containing terephthalic acid and water, (5) cooling terephthalic acid water vapor mixture to a temperature below the dew point of terephthalic acid and (6) collecting the polymer grade terephthalic acid. The polymer grade terephthalic acid and ethylene glycol provided by this process can be used to make high quality terephthalate homopolymers or copolymers for applications including clear bottles and fibers.
    • 用于从聚对苯二甲酸乙二醇酯或其共聚物中回收对苯二甲酸和乙二醇的方法。 该方法是经济的,有利于环境,并提供来自消费后树脂的聚合物级对苯二甲酸和乙二醇。 该方法是六步法,其包括:(1)在升高的温度和压力下使包含聚对苯二甲酸乙二醇酯的树脂与水接触,(2)冷却所得混合物以提供含有对苯二甲酸的固体部分和含有 乙二醇,(3)通过蒸馏从液体部分回收乙二醇,(4)通过在水蒸汽存在下在高温下加热固体部分来回收对苯二甲酸,以产生含有对苯二甲酸和水的蒸汽, (5)将对苯二甲酸水蒸气混合物冷却至低于对苯二甲酸露点的温度,和(6)收集聚合物级对苯二甲酸。 通过该方法提供的聚合物级对苯二甲酸和乙二醇可用于制备用于包括透明瓶和纤维的应用的高质量对苯二甲酸酯均聚物或共聚物。