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1. 发明申请

US20120065696A1 Method and System for Characterizing Supraventricular Rhythm during Cardiac Pacing 有权
标题翻译：心脏起搏过程中表现室性节律的方法与系统
公开(公告)号：US20120065696A1
公开(公告)日：2012-03-15
申请号：US13159686
申请日：2011-06-14
申请人： Joseph Bocek , Jaeho Kim , Anthony S. Harrington , Lorenzo A. DiCarlo , Harley G. White , Phillip D. Foshee , David L. Perschbacher
发明人： Joseph Bocek , Jaeho Kim , Anthony S. Harrington , Lorenzo A. DiCarlo , Harley G. White , Phillip D. Foshee , David L. Perschbacher
IPC分类号： A61N1/365
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.
摘要翻译：用于产生患者室上性节律（SVR）的一搏的表征的方法和系统涉及在心脏起搏时进行这种表征。在SVR表征期间，修改了各种起搏参数，并对患者的室上节律进行了表征，同时对起搏参数进行了修改。 SVR表征过程在单腔和多腔起搏模式中有效。

2. 发明授权

US08583231B2 Method and system for characterizing supraventricular rhythm during cardiac pacing 有权
公开(公告)号：US08583231B2
公开(公告)日：2013-11-12
申请号：US13159686
申请日：2011-06-14
申请人： Joseph Bocek , Jaeho Kim , Anthony S. Harrington , Lorenzo A. DiCarlo , Harley G. White , Phillip D. Foshee , David L. Perschbacher
发明人： Joseph Bocek , Jaeho Kim , Anthony S. Harrington , Lorenzo A. DiCarlo , Harley G. White , Phillip D. Foshee , David L. Perschbacher
IPC分类号： A61N1/00
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.

3. 发明授权

US08649860B2 Adaptive event storage in implantable device 有权
标题翻译：可植入装置中的自适应事件存储
公开(公告)号：US08649860B2
公开(公告)日：2014-02-11
申请号：US12781459
申请日：2010-05-17
申请人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
发明人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
IPC分类号： A61N1/39
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译：使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。

4. 发明授权

US08473042B2 Tachyarrhythmia detection using dynamic duration 有权
标题翻译：快速心律失常检测采用动态持续时间
公开(公告)号：US08473042B2
公开(公告)日：2013-06-25
申请号：US12794346
申请日：2010-06-04
申请人： Jason McCarthy , David L. Perschbacher
发明人： Jason McCarthy , David L. Perschbacher
IPC分类号： A61B5/0464
CPC分类号： A61N1/3621 , A61B5/046
摘要： An apparatus comprises an implantable cardiac signal sensing circuit configured to produce a sensed cardiac signal representative of cardiac activity of a subject and a controller communicatively coupled to the cardiac signal sensing circuit. The controller includes a sensing module configured to detect a cardiac depolarization using the sensed cardiac signal and an arrhythmia detection module. The arrhythmia detection module is configured to detect a depolarization rate or interval that satisfies a first tachyarrhythmia detection rate zone threshold, adjust a specified detection duration threshold for the tachyarrhythmia detection zone according to the detected depolarization rate, declare that the detected depolarization rate is an episode of tachyarrhythmia when the detected depolarization rate is sustained for the adjusted detection duration threshold, and provide an indication of the tachyarrhythmia to a user or process.
摘要翻译：一种装置包括可植入心脏信号感测电路，其被配置为产生代表受试者的心脏活动的感测心脏信号和通信地耦合到心脏信号感测电路的控制器。控制器包括感测模块，其被配置为使用感测的心脏信号和心律失常检测模块来检测心脏去极化。心律失常检测模块被配置为检测满足第一快速心律失常检测率区域阈值的去极化速率或间隔，根据检测到的去极化速率调整快速心律失常检测区域的指定检测持续时间阈值，声明检测到的去极化率是发作当检测到的去极化速率维持在调整的检测持续时间阈值时，并且向使用者或过程提供快速性心律失常的指示，发生快速性心律失常。

5. 发明授权

US08214037B2 Implantable pulse generator and method having adjustable signal blanking 有权
标题翻译：可植入脉冲发生器和具有可调信号消隐的方法
公开(公告)号：US08214037B2
公开(公告)日：2012-07-03
申请号：US13174136
申请日：2011-06-30
申请人： James O. Gilkerson , Doug M. Birkholz , David L. Perschbacher
发明人： James O. Gilkerson , Doug M. Birkholz , David L. Perschbacher
IPC分类号： A61N1/00
CPC分类号： A61N1/3702 , A61N1/3706
摘要： An implantable pulse generator senses a cardiac signal, identifies cardiac events in the cardiac signal, and starts a blanking interval including a repeatable noise window blanking interval in response to each cardiac event. When noise is detected during the repeatable noise window blanking interval, the noise window blanking interval is repeated. In one embodiment, the duration of repeated repeatable noise window blanking intervals is summed and compared to a pacing escape interval. When the sum is greater than the pacing escape interval, asynchronous pacing pulses are delivered until the noise ceases. Alternatively, when the sum is greater than the pacing escape interval, the pace escape interval is repeated.
摘要翻译：植入式脉冲发生器感测心脏信号，识别心脏信号中的心脏事件，并且响应于每个心脏事件开始包括可重复噪声窗口消隐间隔的消隐间隔。当在可重复的噪声窗消隐间隔期间检测到噪声时，重复噪声窗消隐间隔。在一个实施例中，将重复的可重复噪声窗口消隐间隔的持续时间相加并与起搏逃逸间隔进行比较。当总和大于起搏逃生间隔时，异步起搏脉冲将被传递，直到噪声停止。或者，当总和大于起搏逃逸间隔时，重复起搏逃逸间隔。

6. 发明申请

US20120035489A1 RHYTHM DISCRIMINATION ENHANCEMENT - CHAMBER OF TACHY ORIGINATION 有权
标题翻译： RHYTHM歧视改进 - TACHY ORIGINATION室
公开(公告)号：US20120035489A1
公开(公告)日：2012-02-09
申请号：US13196469
申请日：2011-08-02
申请人： Yanting Dong , Deepa Mahajan , David L. Perschbacher
发明人： Yanting Dong , Deepa Mahajan , David L. Perschbacher
IPC分类号： A61B5/0464
CPC分类号： A61B5/0464 , A61B5/4836 , A61B5/7264 , A61N1/3962
摘要： An apparatus comprises an implantable cardiac signal sensing circuit and a controller circuit. The implantable cardiac signal sensing circuit provides a sensed depolarization signal from a ventricle and a sensed depolarization signal from an atrium. The controller circuit includes an onset detection circuit and a classification circuit. The onset detection circuit detects an onset episode that includes fast cardiac depolarizations and identifies a depolarization that initiates the onset episode. The classification circuit classifies the onset episode as supra-ventricular tachycardia (SVT) when the initiating onset episode is identified in the atrium and the number of atrial depolarizations is greater than or equal to the number of ventricular depolarizations during the onset episode, and as ventricular tachycardia (VT) when the initiating onset depolarization is identified in the ventricle and the number of ventricular depolarizations is greater than the number of atrial depolarizations during the onset episode.
摘要翻译：一种装置包括可植入心脏信号感测电路和控制器电路。可植入心脏信号感测电路提供来自心室的感测去极化信号和来自心房的感测去极化信号。控制器电路包括起始检测电路和分类电路。发作检测电路检测包括快速心脏去极化的发作发作，并识别启动发作发作的去极化。分类电路将起始发作分类为室上性心动过速（SVT），当在心房中鉴定起始发作发作时，心房去极化数大于或等于发作发作期间心室去极化数，以及心室在脑室中鉴定起始起始去极化并且心室去极化的数量大于发作期间心房去极化的数量时，心动过速（VT）。

7. 发明申请

US20100069991A1 SYSTEMS AND METHODS FOR HIGHLY SAFE ADJUSTMENT OF DEVICE PARAMETERS 有权
标题翻译：用于高度安全调整设备参数的系统和方法
公开(公告)号：US20100069991A1
公开(公告)日：2010-03-18
申请号：US12559730
申请日：2009-09-15
申请人： Kenneth P. Hoyme , James O. Gilkerson , James Kalgren , David L. Perschbacher
发明人： Kenneth P. Hoyme , James O. Gilkerson , James Kalgren , David L. Perschbacher
IPC分类号： A61N1/08
CPC分类号： A61N1/37247 , A61N1/362 , A61N1/37252 , G06F19/00 , G16H40/63 , G16H50/50
摘要： A system and method of programming a cardiac rhythm management device (CRM device) using an external programming device are described, where the user is presented with a list of highly-safe parameter adjustments. Input is received from the user selecting one or more of the highly-safe parameter adjustments. A programming session is initiated wherein the programming device establishes communication with the CRM device, and transmits the selected one or more highly-safe parameter adjustment to the CRM device.
摘要翻译：描述了使用外部编程设备对心律管理设备（CRM设备）进行编程的系统和方法，其中向用户呈现高度安全的参数调整的列表。从用户接收输入，选择一个或多个高度安全的参数调整。启动编程会话，其中编程设备建立与CRM设备的通信，并且将所选择的一个或多个高度安全的参数调整发送到CRM设备。

8. 发明申请

US20090157135A1 BACKUP PACING DURING TACHYCARDIA 有权
标题翻译：在TACHYCARDIA期间的备份
公开(公告)号：US20090157135A1
公开(公告)日：2009-06-18
申请号：US12326517
申请日：2008-12-02
申请人： David L. Perschbacher , James O. Gilkerson
发明人： David L. Perschbacher , James O. Gilkerson
IPC分类号： A61N1/368
CPC分类号： A61N1/3622 , A61N1/3624 , A61N1/37
摘要： A tachycardia episode can be detected in a subject using a processor, and whether the tachycardia episode is a sustained tachycardia episode can be determined during a period of time. A backup pacing can be provided in response to the detecting tachycardia episode and during the period of time, and a tachycardia therapy can be provided to the subject if the tachycardia episode is determined to be a sustained tachycardia episode.
摘要翻译：可以使用处理器在受试者中检测到心动过速，并且可以在一段时间内确定心动过速发作是否是持续性心动过速发作。可以响应于检测性心动过速发作和在一段时间内提供后备起搏，并且如果心动过速发作被确定为持续性心动过速发作，则可以向受试者提供心动过速治疗。

9. 发明授权

US07376461B2 Dynamic mode switch for early detection of tachyarrhythmia 有权
标题翻译：用于早发性快速性心律失常的动态模式切换
公开(公告)号：US07376461B2
公开(公告)日：2008-05-20
申请号：US10274697
申请日：2002-10-18
申请人： David L. Perschbacher , Kenneth L. Baker
发明人： David L. Perschbacher , Kenneth L. Baker
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/3684
摘要： An algorithm executed in an implantable cardiac rhythm management device (CRMD) automatically adjusts the time that an atrial pace (AP) and/or a ventricular pace (VP) pulse is generated by a pulse generator when the expected time of occurrence of the AP pulse falls within a predetermined interval referred to as the “lowest tachy zone”. By delaying the generation of the AP pulse until outside of the lowest tachy zone, undersensing of ventricular tachycardia depolarizations due to cross-channel refractory and VP refractory is avoided.
摘要翻译：在可植入心律管理装置（CRMD）中执行的算法在预期的AP脉冲发生时间时自动调节由脉冲发生器产生心房速度（AP）和/或心室起搏（VP）脉冲的时间落在被称为“最低速度区”的预定间隔内。通过延迟AP脉冲的产生直到最低速度区域的外部，避免了由于交叉通道耐火材料和VP耐火材料引起的室性心动过速去极化的不足。

10. 发明授权

US07277750B2 Method and apparatus for anti-tachycardia pacing and defibrillation 有权
标题翻译：用于抗心动过速起搏和除颤的方法和装置
公开(公告)号：US07277750B2
公开(公告)日：2007-10-02
申请号：US10817751
申请日：2004-04-02
申请人： David L. Perschbacher , Karin K. Roof , Rebecca Bloomfield
发明人： David L. Perschbacher , Karin K. Roof , Rebecca Bloomfield
IPC分类号： A61N1/362 , A61N1/39
CPC分类号： A61N1/3621 , A61N1/3962 , A61N1/3987
摘要： An implantable cardioverter/defibrillator (ICD) includes an Anti-Tachycardia Pacing Before Charge (ATP-BC) mode according to which one or more high-voltage capacitors for storing defibrillation energy are charged in preparation of delivering a defibrillation shock only if a ventricular tachycardia (VT) sustains after an ATP delivery. Fast ATP delivery and effect verification methods are applied to avoid significant delay in delivering the defibrillation shock when found necessary to terminate the VT. A switch is provided such that a user decides whether to activate the ATP-BC mode or to deliver the defibrillation shock without delivering the ATP.
摘要翻译：植入式心脏复律器/除颤器（ICD）包括在充电前的抗心动过速起搏（ATP-BC）模式，根据该模式，用于存储除颤能量的一个或多个高压电容器用于仅在心室性心动过速（VT）在ATP递送后维持。应用快速的ATP递送和效果验证方法，以避免在发现终止VT时必需的递送除颤电击的显着延迟。提供开关，使得用户决定是否激活ATP-BC模式或者在不输送ATP的情况下递送除颤电击。

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