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1. 发明申请

US20080090226A1 Novel Antigen Constructs Useful In the Detection and Differentiation of Antibodies to HIV 有权
公开(公告)号：US20080090226A1
公开(公告)日：2008-04-17
申请号：US11954356
申请日：2007-12-12
申请人： John Hackett , Julie Yamaguchi , Alan Golden , Catherine Brennan , Robert Hickman , Shushil Devare
发明人： John Hackett , Julie Yamaguchi , Alan Golden , Catherine Brennan , Robert Hickman , Shushil Devare
IPC分类号： C07H21/04 , C07K16/00 , C12N15/00 , C12N5/02 , C12Q1/70
CPC分类号： C07K14/005 , A61K39/00 , C07K2319/00 , C12N2740/16122 , G01N2333/162
摘要： Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.

2. 发明申请

US20080090994A1 Novel Antigen Constructs Useful In the Detection and Differentiation of Antibodies to HIV 有权
标题翻译：用于HIV抗体检测和分化的新型抗原构建体
公开(公告)号：US20080090994A1
公开(公告)日：2008-04-17
申请号：US11954351
申请日：2007-12-12
申请人： John Hackett , Julie Yamaguchi , Alan Golden , Catherine Brennan , Robert Hickman , Sushil Devare
发明人： John Hackett , Julie Yamaguchi , Alan Golden , Catherine Brennan , Robert Hickman , Sushil Devare
IPC分类号： C07K16/00
CPC分类号： C07K14/005 , A61K39/00 , C07K2319/00 , C12N2740/16122 , G01N2333/162
摘要： Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.
摘要翻译：要求保护从HIV-1分离株HAM112获得的分离的HIV-1组O env多肽，以及（a）包含HIV-1组O型多肽和HIV-1组M env中的一种或多种的融合物的抗原构建体多肽和（b）另外的含有其他组O序列的抗原构建物，特别是分离株HAM112的gp41 IDR。还要求保护的是编码上述的多核苷酸序列，包含其的表达载体，由此转化的宿主细胞，以及利用本发明的抗原构建体的免疫测定方法和试剂盒。

3. 发明申请

US20060153866A1 Novel antigen constructs useful in the detection and differentiation of antibodies to HIV 有权
公开(公告)号：US20060153866A1
公开(公告)日：2006-07-13
申请号：US11008351
申请日：2004-12-09
申请人： John Hackett , Julie Yamaguchi , Alan Golden , Catherine Brennan , Robert Hickman , Sushil Devare
发明人： John Hackett , Julie Yamaguchi , Alan Golden , Catherine Brennan , Robert Hickman , Sushil Devare
IPC分类号： A61K39/21 , C07K14/16
CPC分类号： C07K14/005 , A61K39/00 , C07K2319/00 , C12N2740/16122 , G01N2333/162
摘要： Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.

4. 外观设计

USD751304S1 Attachable tool and dust tray for artist's easel 有权
标题翻译：适用于艺术家画架的工具和除尘托盘
公开(公告)号：USD751304S1
公开(公告)日：2016-03-15
申请号：US29487439
申请日：2014-04-08
申请人： Robert Hickman
设计人： Robert Hickman

5. 发明授权

US07874033B2 Universal support pillow 有权
标题翻译：通用支撑枕头
公开(公告)号：US07874033B2
公开(公告)日：2011-01-25
申请号：US12419591
申请日：2009-04-07
申请人： Brandon Palmer , Robert Hickman
发明人： Brandon Palmer , Robert Hickman
IPC分类号： A47G9/10
CPC分类号： A47G9/10
摘要： A universal support pillow usable by both back and side sleepers includes a first chamber having multiple filled compartments that define a first side of the pillow and a second filled chamber that defines a second side of the pillow. The multiple compartments of the first chamber are designed particularly to receive a head of a back sleeper, and the second chamber is designed to receive a head of a side sleeper. The universal support pillow, in one version, includes a closable opening that is disposed between the two chambers for receiving a pillow insert to provide user-customized thickness and firmness characteristics of the universal support pillow. Multiple types of pillow inserts having different thickness and/or firmness characteristics may be provided, wherein a user is able to select one of the pillow inserts based on the user's sleep pillow preferences.
摘要翻译：通过后枕和枕头都可以使用的通用支撑枕包括具有限定枕头第一侧的多个填充隔室的第一室和限定枕头第二侧的第二填充室。第一室的多个隔室被设计成特别地用于容纳后卧铺的头部，并且第二室被设计成接收侧卧铺的头部。通用支撑枕头在一个版本中包括一个可关闭的开口，该开口设置在两个腔室之间，用于接收枕头插入件，以提供用户定制的通用支撑枕头的厚度和坚固度特性。可以提供具有不同厚度和/或坚固性特征的多种类型的枕头插入件，其中用户能够基于使用者的睡眠枕头偏好来选择一个枕头插入物。

6. 外观设计

USD750909S1 Attachable tool tray for artist's easel 有权
标题翻译：用于艺术家画架的可附装工具托盘
公开(公告)号：USD750909S1
公开(公告)日：2016-03-08
申请号：US29487344
申请日：2014-04-08
申请人： Robert Hickman
设计人： Robert Hickman

7. 外观设计

USD750908S1 Attachable artist's easel 有权
标题翻译：可附加艺术家的画架
公开(公告)号：USD750908S1
公开(公告)日：2016-03-08
申请号：US29504363
申请日：2014-10-05
申请人： Robert Hickman
设计人： Robert Hickman

8. 发明授权

US07394914B2 Single pass off-line video encoding 有权
标题翻译：单通离线视频编码
公开(公告)号：US07394914B2
公开(公告)日：2008-07-01
申请号：US10857182
申请日：2004-06-01
申请人： Robert Hickman
发明人： Robert Hickman
IPC分类号： G06K9/00
CPC分类号： B07C3/00
摘要： Method of automatically sorting mail 1 which has to be forwarded by means of a sorting machine, which processes the mail 1 in a continuous main stream A and where the sorting machine comprises a feeder 2 via which a variety of unsorted addressed mail is fed. The singled mail 1 is marked with an individualising identifier by a following marking device. Each identifier is assigned to a data set in a file, and by means of a following reading device 5 the addresses on the mail 1 are taken up. A taken-up address is deciphered by a recognition module and is written in the corresponding data set. The mail 1 is assigned a corresponding error information when the address cannot be deciphered. A mail piece with assigned error information is then sorted out of the main stream as scrap mail 6. The scrap mail 6 is fed again together with the unsorted mail 1 into the feeder 2 after the address has been verified and has been written in the corresponding data set, and the fed again scrap mail 6 is automatically recognised as such.
摘要翻译：自动排序必须通过分拣机转发的邮件1的方法，该分拣机处理连续主流A中的邮件1，并且其中分拣机包括馈送各种未分拣的寻址邮件的馈送器2。单张邮件1由以下标记装置标记有个性化标识符。每个标识符被分配给文件中的数据集，并且通过以下读取装置5，邮件1上的地址被占用。占用地址由识别模块解密并写入相应的数据集。当地址不能被解密时，邮件1被分配相应的错误信息。然后将具有分配的错误信息的邮件从主流中作为废品邮件6进行排序。在地址已经被验证并且已经被写入相应的数据集之后，将废料6再次与未排序的邮件1一起馈送到馈线2中，并且再次馈送的废品邮件6被自动识别。

9. 发明申请

US20070265584A1 VENOUS PROSTHESIS AND VASCULAR GRAFT WITH ACCESS PORT 审中-公开
标题翻译：门静脉和血管通路
公开(公告)号：US20070265584A1
公开(公告)日：2007-11-15
申请号：US11675348
申请日：2007-02-15
申请人： Robert Hickman , Marc Jaker
发明人： Robert Hickman , Marc Jaker
IPC分类号： A61M39/02
CPC分类号： A61M39/0247 , A61F2/06 , A61M1/3653 , A61M1/3659 , A61M39/02 , A61M2039/0258 , A61M2039/0261 , A61M2039/027
摘要： A venous polytetrafluoroethylene (PTFE) graft with integral access port system. The graft may have one, two, or more ports, which then exits the skin. The prosthesis may be made of fluoropolymer tubing fabricated in such a way as to involve several performance features. The graft may have holes for suturing, anchoring, or bio-integration to the artery. The ports have natural acting restrictions or valves at the graft juncture, throughout the implanted part body of the device and at the exit site. The ports are also naturally self-purging. A port may also incorporate a redundant hermetic hemostatic valve and closure system at the exit site.
摘要翻译：一种具有整体进入口系统的静脉聚四氟乙烯（PTFE）移植物。移植物可以具有一个，两个或更多个端口，然后离开皮肤。假体可以由以聚合物管制成，以便涉及若干性能特征。移植物可以具有用于缝合，锚定或生物整合到动脉的孔。这些端口在移植物接合处具有自然作用限制或瓣膜，贯穿整个植入的部件本体和出口部位。这些港口也是自然清洗。港口还可以在出口处加入多余的密封止血阀和关闭系统。

10. 发明申请

US20070260216A1 VASCULAR ACCESS CATHETER 审中-公开
标题翻译：血管通道导管
公开(公告)号：US20070260216A1
公开(公告)日：2007-11-08
申请号：US11675281
申请日：2007-02-15
申请人： Robert Hickman , Marc Jaker
发明人： Robert Hickman , Marc Jaker
IPC分类号： A61M31/00
CPC分类号： A61M25/0017 , A61M25/0097 , A61M25/02 , A61M25/0693 , A61M2025/0025 , A61M2025/0286
摘要： An indwelling Fluoropolymer catheter primarily intended for vascular access. The catheter comprises a thin, lubricous sleeve circumferentially folded back over the leading edge of a pusher or positioning tube, affixed to a distal Hemostatic valve/guide assembly. The catheter may, in one embodiment, incorporate a needle or trocar for rapid deployment, which is loaded/positioned from the leading edge, back into the film membrane. The trocar may pierce the skin and advance through body tissues to an artery or vessel. The catheter is then inverted over the pusher tube following the guide of the trocar and optionally a guide wire into the artery. The trocar or needle will be totally withdrawn after catheter placement.
摘要翻译：主要用于血管通路的留置氟聚合物导管。导管包括一个薄的，润滑的套筒，周向地折叠在推动器或定位管的前缘上，固定到远端止血阀/引导组件。在一个实施例中，导管可以包括用于快速展开的针或套管针，其从前缘装载/定位回膜膜。套管针可刺穿皮肤并穿过身体组织进入动脉或血管。导管然后在套管针的引导件上并且可选地导引入动脉中的推动器管上倒置。导管放置后套管针或针头将完全拔出。

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