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1. 发明授权

US07629327B2 Chlamydia 60 Kda CRMP antigens and vaccine uses 失效
标题翻译：衣原体60 Kda CRMP抗原和疫苗用途
公开(公告)号：US07629327B2
公开(公告)日：2009-12-08
申请号：US11898220
申请日：2007-09-11
申请人： Andrew D. Murdin , Raymond P. Oomen , Joe Wang , Pamela Dunn
发明人： Andrew D. Murdin , Raymond P. Oomen , Joe Wang , Pamela Dunn
IPC分类号： A61K31/70
CPC分类号： A61K31/711 , A61K39/118 , A61K2039/53 , C07K14/295 , Y10S435/975
摘要： The present invention provides vaccines and methods for immunizing a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae. The vaccine and method employ a 60 kDa cysteine-rich membrane protein of a strain of Chlamydia pneumoniae. Modifications are possible within the scope of this invention.
摘要翻译：本发明提供用于免疫宿主（包括人）免疫衣原体特异性肺炎衣原体感染引起的疾病的疫苗和方法。疫苗和方法使用肺炎衣原体菌株的60kDa富含半胱氨酸的膜蛋白。在本发明的范围内可以进行修改。

2. 发明授权

US07553493B2 Chlamydia flagellar protein antigen 有权
标题翻译：衣原体鞭毛蛋白抗原
公开(公告)号：US07553493B2
公开(公告)日：2009-06-30
申请号：US11905430
申请日：2007-10-01
申请人： Andrew D. Murdin , Raymond P. Oomen , Joe Wang
发明人： Andrew D. Murdin , Raymond P. Oomen , Joe Wang
IPC分类号： A61K39/118 , A61K39/02 , C12P21/04 , C12P21/06 , C07H21/04
CPC分类号： G01N33/56927 , A61K39/00 , C07K14/295 , C07K2319/00 , Y02A50/472 , Y02A50/476
摘要： The present invention provides purified and isolated polynucleotide molecules that encode Chlamydia polypeptides which can be used in methods to prevent, treat, and diagnose Chlamydia infection. In one form of the invention, the polynucleotide molecules encode polypeptides CPN100988 RY-68 (SEQ ID Nos:13 and 26).
摘要翻译：本发明提供了编码衣原体多肽的纯化和分离的多核苷酸分子，其可用于预防，治疗和诊断衣原体感染的方法。在本发明的一种形式中，多核苷酸分子编码多肽CPN100988 RY-68（SEQ ID NO：13和26）。

3. 发明授权

US07509821B1 Yarn measuring device for flat bed knitting machines 失效
标题翻译：平床针织机用纱线测量装置
公开(公告)号：US07509821B1
公开(公告)日：2009-03-31
申请号：US12122958
申请日：2008-05-19
申请人： Yu-Sheng Lin , Joe Wang
发明人： Yu-Sheng Lin , Joe Wang
IPC分类号： D04B15/48
CPC分类号： D04B35/12
摘要： A yarn measuring device for a flat bed knitting machine which has a chassis, a needle bed, a track and a carriage. The carriage has a cam controller and a mask plate. The yarn measuring device includes a counter, a detection unit and a programmable logic circuit controller. The programmable logic circuit controller, the counter, the detection unit, the carriage and the cam controller are electrically interconnected. Knitting stitches can be measured in a bidirectional fashion. Measuring accuracy improves, measured value can be read directly and easier, and the position of cams can be adjusted quickly. Total yarn requirement can be calculated accurately, fabric quality can be improved and production efficiency can be enhanced.
摘要翻译：一种用于平床机的纱线测量装置，其具有底盘，针床，轨道和托架。滑架具有凸轮控制器和掩模板。纱线测量装置包括计数器，检测单元和可编程逻辑电路控制器。可编程逻辑电路控制器，计数器，检测单元，托架和凸轮控制器电互连。针织针脚可以双向测量。测量精度提高，测量值可以直接读取更容易，凸轮位置可以快速调整。可以准确计算总纱需求量，提高织物质量，提高生产效率。

4. 发明申请

US20080032429A1 Methods, defect review tools, and systems for locating a defect in a defect review process 有权
标题翻译：方法，缺陷评估工具和用于在缺陷评估过程中定位缺陷的系统
公开(公告)号：US20080032429A1
公开(公告)日：2008-02-07
申请号：US11270771
申请日：2005-11-09
申请人： Da Chen , Christophe Fouquet , Saibal Banerjee , Santosh Bhattacharyya , Joe Wang , Lian Yao , Mike van Riet , Igor Germanenko
发明人： Da Chen , Christophe Fouquet , Saibal Banerjee , Santosh Bhattacharyya , Joe Wang , Lian Yao , Mike van Riet , Igor Germanenko
IPC分类号： H01L21/66
CPC分类号： G06T7/001 , G01N21/8851 , G01N21/9501 , G01N21/95607 , G06T2207/30148
摘要： Methods, defect review tools, and systems for locating a defect in a defect review process are provided. One method includes acquiring one or more images and data from an inspection tool. The one or more images illustrate an area on a specimen in which a defect to be reviewed is located. The data indicates a position and features of the defect within the area. The method also includes acquiring one or more additional images of the specimen proximate the position of the defect indicated in the data using an imaging subsystem of a defect review tool. In addition, the method includes identifying a portion of the one or more additional images that corresponds to the one or more images. The method further includes determining a position of the defect within the portion of the one or more additional images using the data.
摘要翻译：提供了用于定位缺陷评估过程中的缺陷的方法，缺陷评估工具和系统。一种方法包括从检查工具获取一个或多个图像和数据。一个或多个图像示出了待检查的缺陷所在的样本上的区域。数据表示该区域内缺陷的位置和特征。该方法还包括使用缺陷评估工具的成像子系统获取在数据中指示的缺陷的位置附近的样本的一个或多个附加图像。此外，该方法包括识别对应于一个或多个图像的一个或多个附加图像的一部分。所述方法还包括使用所述数据确定所述一个或多个附加图像的所述部分内的所述缺陷的位置。

5. 发明申请

US20050202048A1 Chlamydia antigens and vaccine uses of the protein 失效
标题翻译：衣原体抗原和疫苗用途的蛋白质
公开(公告)号：US20050202048A1
公开(公告)日：2005-09-15
申请号：US11118381
申请日：2005-05-02
申请人： Andrew Murdin , Raymond Oomen , Joe Wang , Pamela Dunn
发明人： Andrew Murdin , Raymond Oomen , Joe Wang , Pamela Dunn
IPC分类号： G01N33/53 , A61K39/00 , A61K39/118 , A61K39/39 , A61K39/395 , A61K48/00 , A61P9/10 , A61P11/00 , A61P11/02 , A61P11/06 , A61P31/04 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/31 , C12N15/85 , C12P21/02 , C12Q1/68 , G01N33/566 , G01N33/569 , A61K9/127 , A61K31/7052 , A61K31/65
CPC分类号： C12N15/85 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K14/295 , C07K2319/00 , C12N2830/42 , Y02A50/472 , Y02A50/476 , Y10S435/975
摘要： The present invention provides vaccines and methods for immunizing a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae. The vaccine and method employ a full-length, 5′-truncated or 3′-truncated 76kDa protein of a strain of Chlamydia pneumoniae. Modifications are possible within the scope of this invention.
摘要翻译：本发明提供用于免疫宿主（包括人）免疫衣原体特异性肺炎衣原体感染引起的疾病的疫苗和方法。疫苗和方法使用肺炎衣原体菌株的全长5'截短或3'截短的76kDa蛋白。在本发明的范围内可以进行修改。

6. 发明申请

US20050069942A1 Chlamydia antigens and corresponding DNA fragments and uses thereof 失效
标题翻译：衣原体抗原和相应的DNA片段及其用途
公开(公告)号：US20050069942A1
公开(公告)日：2005-03-31
申请号：US10976917
申请日：2004-11-01
申请人： Andrew Murdin , Raymond Oomen , Joe Wang , Pamela Dunn
发明人： Andrew Murdin , Raymond Oomen , Joe Wang , Pamela Dunn
IPC分类号： G01N33/569 , A61K31/711 , A61K38/00 , A61K39/118 , A61K39/395 , A61K48/00 , A61P11/00 , A61P31/04 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/31 , C12P21/02 , C12Q1/68 , C07H21/04 , C12N15/74
CPC分类号： A61K31/711 , A61K39/118 , A61K2039/53 , C07K14/295 , Y10S435/975
摘要： The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector containing a nucleotide sequence encoding a 60 kDa cysteine-rich membrane protein of a strain of Chlamydia pneumoniae and a promoter to effect expression of the 60 kDa cysteine-rich membrane protein gene in the host. Modifications are possible within the scope of this invention.
摘要翻译：本发明提供了包含DNA，宿主（包括人）在内的免疫针对由衣原体特异性肺炎衣原体感染引起的疾病的核酸的方法，其使用含有编码60kDa半胱氨酸 - 肺炎衣原体菌株的富含膜蛋白和在宿主中有效表达60kDa富含半胱氨酸的膜蛋白基因的启动子。在本发明的范围内可以进行修改。

7. 发明申请

US20050002944A1 Chlamydia antigens and corresponding DNA fragments and uses thereof 失效
标题翻译：衣原体抗原和相应的DNA片段及其用途
公开(公告)号：US20050002944A1
公开(公告)日：2005-01-06
申请号：US10746251
申请日：2003-12-29
申请人： Andrew Murdin , Raymond Oomen , Joe Wang , Pamela Dunn
发明人： Andrew Murdin , Raymond Oomen , Joe Wang , Pamela Dunn
IPC分类号： G01N33/50 , A61K9/127 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/02 , A61K39/118 , A61K39/395 , A61K48/00 , A61P11/00 , A61P31/00 , C07K14/295 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/31 , C12P21/02 , C12Q1/68 , C12R1/01 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/569 , A61K39/38
CPC分类号： A61K9/127 , A61K39/00 , A61K39/118 , A61K2039/53 , C07K14/295 , C07K2319/00 , Y02A50/396 , Y02A50/472 , Y02A50/476 , Y10S435/975
摘要： The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector containing a nucleotide sequence encoding OMP (outer membrane protein) of a strain of Chlamydia pneumoniae and a promoter to effect expression of the OMP (outer membrane protein) gene in the host. Modifications are possible within the scope of this invention.
摘要翻译：本发明提供了一种核酸的方法，包括DNA，宿主（包括人）免疫针对由衣原体特异性肺炎衣原体感染引起的疾病，使用含有编码OMP的核苷酸序列的载体（外膜蛋白）肺炎衣原体的菌株和在宿主中影响OMP（外膜蛋白）基因表达的启动子。在本发明的范围内可以进行修改。

8. 发明授权

US06808713B1 Chlamydia antigens and corresponding DNA fragments and uses thereof 失效
标题翻译：衣原体抗原和相应的DNA片段及其用途
公开(公告)号：US06808713B1
公开(公告)日：2004-10-26
申请号：US09869433
申请日：2001-10-16
申请人： Andrew D. Murdin , Raymond P. Oomen , Joe Wang , Pamela Dunn
发明人： Andrew D. Murdin , Raymond P. Oomen , Joe Wang , Pamela Dunn
IPC分类号： A61K39118
CPC分类号： G01N33/56927 , A61K38/00 , A61K39/00 , A61K2039/53 , C07K14/295 , Y10S530/811 , Y10S530/814 , Y10S530/82
摘要： The present invention provides a method of immunizing a host against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae. The method involves nucleic acid immunization, including DNA immunization, and employs a vector containing a nucleotide sequence which encodes an ATP/ADP translocase of a strain of Chlamydia pneumoniae. The nucleotide sequence is operably linked to a promoter to effect expression of the ATP/ADP translocase in the host. The host may be a human host. Modifications are possible within the scope of this invention.
摘要翻译：本发明提供了免疫宿主免受衣原体特异性肺炎衣原体感染引起的疾病的方法。该方法包括核酸免疫，包括DNA免疫，并使用含有编码肺炎衣原体菌株的ATP / ADP转位酶的核苷酸序列的载体。核苷酸序列与启动子可操作地连接以在宿主中实现ATP / ADP转位酶的表达。主人可能是一个人的主人。在本发明的范围内可以进行修改。

9. 发明授权

US08624186B2 Movable detector for charged particle beam inspection or review 有权
标题翻译：用于带电粒子束检测或检查的可移动检测器
公开(公告)号：US08624186B2
公开(公告)日：2014-01-07
申请号：US12787139
申请日：2010-05-25
申请人： Yi-Xiang Wang , Joe Wang , Xuedong Liu , Zhongwei Chen
发明人： Yi-Xiang Wang , Joe Wang , Xuedong Liu , Zhongwei Chen
IPC分类号： H01J37/244
CPC分类号： H01J37/244 , H01J37/28 , H01J2237/024 , H01J2237/24465 , H01J2237/24475 , H01J2237/2448 , H01J2237/24495 , H01J2237/2611 , H01J2237/2817
摘要： The present invention generally relates to a detection unit of a charged particle imaging system. More particularly, portion of the detection unit can move into or out of the detection system as imaging condition required. With the assistance of a Wein filter (also known as an E×B charged particle analyzer) and a movable detector design, the present invention provides a stereo imaging system that suitable for both low current, high resolution mode and high current, high throughput mode. Merely by way of example, the invention has been applied to a scanning electron beam inspection system. But it would be recognized that the invention could apply to other system using charged particle beam as an observation tool.
摘要翻译：本发明一般涉及带电粒子成像系统的检测单元。更具体地，检测单元的一部分可以作为所需的成像条件移入或移出检测系统。在Wein滤波器（也称为E×B带电粒子分析仪）和可移动检测器设计的帮助下，本发明提供了一种适用于低电流，高分辨率模式和高电流，高通量模式的立体成像系统。仅作为示例，本发明已经应用于扫描电子束检查系统。但是应当认识到，本发明可以应用于使用带电粒子束作为观测工具的其它系统。

10. 发明授权

US07919760B2 Operation stage for wafer edge inspection and review 失效
标题翻译：晶圆边缘检查和检查的操作阶段
公开(公告)号：US07919760B2
公开(公告)日：2011-04-05
申请号：US12331336
申请日：2008-12-09
申请人： Jack Jau , Hong Xiao , Joe Wang , Zhongwei Chen , Yi Xiang Wang , Edward Tseng
发明人： Jack Jau , Hong Xiao , Joe Wang , Zhongwei Chen , Yi Xiang Wang , Edward Tseng
IPC分类号： G21K5/10
CPC分类号： H01J37/28 , H01J37/20 , H01J2237/202 , H01J2237/2817 , H01L21/67288 , H01L21/6831
摘要： The present invention relates to an operation stage of a charged particle beam apparatus which is employed in a scanning electron microscope for substrate (wafer) edge and backside defect inspection or defect review. However, it would be recognized that the invention has a much broader range of applicability. A system and method in accordance with the present invention provides an operation stage for substrate edge inspection or review. The inspection region includes top near edge, to bevel, apex, and bottom bevel. The operation stage includes a supporting stand, a z-stage, an X-Y stage, an electrostatic chuck, a pendulum stage and a rotation track. The pendulum stage mount with the electrostatic chuck has the ability to swing from 0° to 180° while performing substrate top bevel, apex and bottom bevel inspection or review. In order to keep the substrate in focus and avoid a large position shift during altering the substrate observation angle by rotation the pendulum stage, one embodiment of the present invention discloses a method such that the rotation axis of the pendulum stage consist of the tangent of upper edge of the substrate to be inspected. The electrostatic chuck of the present invention has a diameter smaller than which of the substrate to be inspected. During the inspection process the substrate on the electrostatic chuck may be rotated about the central axis on the electrostatic chuck to a desired position, this design insures all position on the bevel and apex are able to be inspected.
摘要翻译：本发明涉及用于基板（晶片）边缘和背面缺陷检查或缺陷检查的扫描电子显微镜中的带电粒子束装置的操作阶段。然而，应当认识到，本发明具有更广泛的应用范围。根据本发明的系统和方法提供了用于衬底边缘检查或审查的操作阶段。检查区域包括顶部近边缘，斜面，顶点和底部斜面。操作台包括支撑台，z台，X-Y台，静电卡盘，摆台和旋转轨道。具有静电卡盘的摆台安装具有从0°摆动到180°的能力，同时执行基板顶部斜面，顶部和底部斜面检查或检查。为了将基板保持在对焦状态，并且通过旋转摆锤台来改变基板观察角度而避免大的位置偏移，本发明的一个实施例公开了一种方法，使得摆台的旋转轴线由上部的切线要检查的基板的边缘。本发明的静电卡盘的直径小于要检查的基板的直径。在检查过程中，静电卡盘上的基板可以围绕静电卡盘上的中心轴线旋转到期望的位置，该设计确保能够检查斜面上的所有位置和顶点。

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