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1. 发明申请

US20120122848A1 (+)-3-HYDROXYMORPHINAN DERIVATIVES AS NEUROPROTECTANTS 审中-公开
标题翻译：（+） - 3-羟基吗啡衍生物作为神经营养因子
公开(公告)号：US20120122848A1
公开(公告)日：2012-05-17
申请号：US13387563
申请日：2010-07-28
申请人： Jinhwa Lee , Jong Yup Kim , Kwang-Seop Song , Jeongmin Kim , Kwang Woo Ahn , Yonggyu Kong
发明人： Jinhwa Lee , Jong Yup Kim , Kwang-Seop Song , Jeongmin Kim , Kwang Woo Ahn , Yonggyu Kong
IPC分类号： A61K31/485 , C07D491/08 , C07D401/10 , C07D405/12 , A61P25/16 , A61K31/55 , A61K31/496 , A61K31/5377 , A61P25/28 , C07D221/28 , C07D413/10
CPC分类号： C07D221/28
摘要： A novel (+)-3-hydroxymorphinan derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating a neurodegenerative disease, are provided.
摘要翻译：提供了一种新型（+） - 3-羟基吗啡喃衍生物和包含其作为活性成分的药物组合物，其可用于预防或治疗神经变性疾病。

2. 发明申请

US20080262066A1 Azole Derivatives as Cannabinoid CB1 Receptor Antagonists 审中-公开
标题翻译：唑类衍生物作为大麻素CB1受体拮抗剂
公开(公告)号：US20080262066A1
公开(公告)日：2008-10-23
申请号：US12105460
申请日：2008-04-18
申请人： Jinhwa LEE , Jeongmin Kim , Kwang-Seop Song , Min Ah Kim , Jong Yup Kim , Suk Ho Lee , Hee Jeong Seo , Sung-Han Lee , Myung Eun Jung , Kwang Woo Ahn , Eun Jung Son
发明人： Jinhwa LEE , Jeongmin Kim , Kwang-Seop Song , Min Ah Kim , Jong Yup Kim , Suk Ho Lee , Hee Jeong Seo , Sung-Han Lee , Myung Eun Jung , Kwang Woo Ahn , Eun Jung Son
IPC分类号： A61K31/415 , C07D231/14 , A61K31/4164 , A61P3/00 , C07D233/54
CPC分类号： C07D231/14 , C07D233/90
摘要： A novel azole compound of formula (I) or a pharmaceutically acceptable salt thereof is effective as a cannabinoid CB1 receptor inverse agonist or antagonist, which is useful for preventing or treating obesity and obesity-related metabolic disorders. The prevention also provides a method for preparing same, a pharmaceutical composition containing same, and a method for preventing or treating obesity and obesity-related metabolic disorders.
摘要翻译：式（I）的新型唑化合物或其药学上可接受的盐作为大麻素CB 1受体反向激动剂或拮抗剂是有效的，其可用于预防或治疗肥胖症和与肥胖有关的代谢紊乱。预防还提供其制备方法，含有其的药物组合物，以及预防或治疗肥胖症和肥胖相关的代谢紊乱的方法。

3. 发明申请

US20120115881A1 NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 有权
标题翻译：新颖的含有阿维菌素的咪唑烷四羧酰胺衍生物和包含其的药物组合物
公开(公告)号：US20120115881A1
公开(公告)日：2012-05-10
申请号：US13383143
申请日：2010-07-09
申请人： Jinhwa Lee , Hee Jeong Seo , Suk Youn Kang , Eun-Jung Park , Min Ju Kim , Suk Ho Lee , Jong yup Kim , Jeongmin Kim , Myung Eun Jung , Hyun Jung Kim , Mi-soon Kim , Ho kyun Han , Kwang Woo Ahn , Min Woo Lee , Ki-Nam Lee , Ae Nim Pae , Woo-Kyu Park
发明人： Jinhwa Lee , Hee Jeong Seo , Suk Youn Kang , Eun-Jung Park , Min Ju Kim , Suk Ho Lee , Jong yup Kim , Jeongmin Kim , Myung Eun Jung , Hyun Jung Kim , Mi-soon Kim , Ho kyun Han , Kwang Woo Ahn , Min Woo Lee , Ki-Nam Lee , Ae Nim Pae , Woo-Kyu Park
IPC分类号： A61K31/497 , A61P25/24 , C07D403/12
CPC分类号： C07D417/14 , A61K31/496 , C07D233/88 , C07D401/12 , C07D403/06 , C07D405/04
摘要： A novel arylpiperazine-containing imidazole 4-carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating a depressive disorder are provided.
摘要翻译：提供了一种新的含有芳基哌嗪的咪唑-4-甲酰胺衍生物或其药学上可接受的盐，以及包含其作为预防或治疗抑郁障碍的活性成分的药物组合物。

4. 发明申请

US20130217672A1 (+)-3-HYDROXYMORPHINAN-BASED POLYCYCLE DERIVATIVES 审中-公开
标题翻译：（+） - 3-羟基吡啶基聚合衍生物
公开(公告)号：US20130217672A1
公开(公告)日：2013-08-22
申请号：US13696246
申请日：2011-05-13
申请人： Jinhwa Lee , Jong Yup Kim , Jeongmin Kim , Kwang Woo Ahn
发明人： Jinhwa Lee , Jong Yup Kim , Jeongmin Kim , Kwang Woo Ahn
IPC分类号： C07D498/08 , C07D471/08 , C07D491/08
CPC分类号： C07D498/08 , C07D471/08 , C07D491/08
摘要： A (+)-3-hydroxymorphinan-based polycycle derivative of formula (I) is effective as a neuroprotective agent for neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and ischemic stroke.
摘要翻译：式（I）的（+） - 3-羟基吗啡喃基多环衍生物作为包括阿尔茨海默病，帕金森病，亨廷顿病，肌萎缩性侧索硬化和缺血性中风的神经变性疾病的神经保护剂是有效的。

5. 发明授权

US08835436B2 Arylpiperazine-containing imidazole 4-carboxamide derivatives and pharmaceutical composition comprising same 有权
标题翻译：含有芳基哌嗪的咪唑4-甲酰胺衍生物和包含其的药物组合物
公开(公告)号：US08835436B2
公开(公告)日：2014-09-16
申请号：US13383143
申请日：2010-07-09
申请人： Jinhwa Lee , Hee Jeong Seo , Suk Youn Kang , Eun-Jung Park , Min Ju Kim , Suk Ho Lee , Jong Yup Kim , Jeongmin Kim , Myung Eun Jung , Hyun Jung Kim , Mi-soon Kim , Ho Kyun Han , Kwang Woo Ahn , Min Woo Lee , Ki-Nam Lee , Ae Nim Pae , Woo-Kyu Park
发明人： Jinhwa Lee , Hee Jeong Seo , Suk Youn Kang , Eun-Jung Park , Min Ju Kim , Suk Ho Lee , Jong Yup Kim , Jeongmin Kim , Myung Eun Jung , Hyun Jung Kim , Mi-soon Kim , Ho Kyun Han , Kwang Woo Ahn , Min Woo Lee , Ki-Nam Lee , Ae Nim Pae , Woo-Kyu Park
IPC分类号： A61K31/496 , C07D233/88 , C07D401/12 , C07D403/06 , C07D405/04 , C07D417/14
CPC分类号： C07D417/14 , A61K31/496 , C07D233/88 , C07D401/12 , C07D403/06 , C07D405/04
摘要： A novel arylpiperazine-containing imidazole 4-carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating a depressive disorder are provided.
摘要翻译：提供了一种新的含有芳基哌嗪的咪唑-4-甲酰胺衍生物或其药学上可接受的盐，以及包含其作为预防或治疗抑郁障碍的活性成分的药物组合物。

6. 发明申请

US20090149899A1 Functional Shoes In Which Stimulant For Extension Growth Acceleration Is Equipped 审中-公开
标题翻译：功能性鞋子，其中用于延长生长加速度的刺激剂
公开(公告)号：US20090149899A1
公开(公告)日：2009-06-11
申请号：US12368085
申请日：2009-02-09
申请人： Kwang Woo Ahn
发明人： Kwang Woo Ahn
IPC分类号： A43B7/00 , A43B13/20
CPC分类号： A43B7/00 , A43B3/0005 , A43B3/30 , A43B7/146 , A43B7/20
摘要： The present invention relates to a pair of functional shoes, which enables both physical stimulation and electrical stimulation to be transmitted to the heel portions of feet and specific portions of ankles, which are helpful in promoting height growth, using the force that is generating while walking, thus stimulating growth plates. Each of the functional shoes an ankle contact member mounted to the heel counter of the shoe, which supports the rear portion of a foot, which ranges from the heel of a foot to an ankle, formed in a shape that corresponds to the concave shape of the rear portion of the ankle, and coming into contact with an ankle stimulation portion; an ankle stimulating member mounted from the inside of a shoe outsole to the ankle contact member, and transmitting physical stimulation to the ankle stimulation portion, which is the concave rear portion of the ankle malleolus, using force that is applied by the foot while walking; a heel stimulating member mounted in the shoe outsole, which corresponds to the central portion of the rear portion of a sole, formed to have hardness higher than the outsole, and transmitting load stimulation, caused by applied force, to a heel stimulation portion, which corresponds to the central portion of the rear portion of the sole; and an electrical stimulation unit, comprising a power generation device which is mounted in the shoe outsole and generates power, and power generation points which are formed on an ankle stimulation part and/or the heel stimulation portion.
摘要翻译：本发明涉及一对功能性鞋，其使物理刺激和电刺激能够使用在行走期间产生的力而传播到足部的脚后跟部分和脚踝的特定部分，这有助于促进身高的增长，从而刺激生长板。功能鞋的每个功能鞋子安装到鞋的鞋跟柜台上，踝接触件支撑脚的后部，脚的后部从足部的脚跟到踝部，其形状形成为与凹部的凹形形状相对应的形状脚踝的后部并与脚踝刺激部接触; 脚踝刺激构件，其从鞋底的内侧安装到脚踝接触构件，并且使用在步行期间由脚施加的力将身体刺激传递到作为踝踝的凹后部的踝刺激部; 安装在鞋外底中的脚跟刺激构件，其对应于鞋底后部的中心部分，其形成为具有高于外底的硬度，并且将由施加的力引起的负载刺激传递到脚后跟刺激部分，对应于鞋底后部的中心部分; 以及电刺激单元，其包括安装在鞋外底中并产生动力的发电装置，以及形成在脚踝刺激部和/或脚后跟刺激部上的发电点。

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