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1. 发明授权

US08584506B2 Physics-based signal processing algorithms for micromachined cantilever arrays 有权
标题翻译：用于微加工悬臂阵列的基于物理的信号处理算法
公开(公告)号：US08584506B2
公开(公告)日：2013-11-19
申请号：US11435495
申请日：2006-05-16
申请人： James V. Candy , David S. Clague , Christopher L. Lee , Robert E. Rudd , Alan K. Burnham , Joseph W. Tringe
发明人： James V. Candy , David S. Clague , Christopher L. Lee , Robert E. Rudd , Alan K. Burnham , Joseph W. Tringe
IPC分类号： G01N9/00 , G01N31/00
CPC分类号： G01N29/036 , G01N2291/0256
摘要： A method of using physics-based signal processing algorithms for micromachined cantilever arrays. The methods utilize deflection of a micromachined cantilever that represents the chemical, biological, or physical element being detected. One embodiment of the method comprises the steps of modeling the deflection of the micromachined cantilever producing a deflection model, sensing the deflection of the micromachined cantilever and producing a signal representing the deflection, and comparing the signal representing the deflection with the deflection model.
摘要翻译：一种使用基于物理学的信号处理算法进行微机械悬臂阵列的方法。该方法利用表示所检测的化学，生物或物理元件的微机械悬臂的偏转。该方法的一个实施例包括以下步骤：对产生偏转模型的微机械悬臂的偏转进行建模，感测微机械悬臂的偏转并产生表示偏转的信号，并将表示偏转的信号与偏转模型进行比较。

2. 发明授权

US07463690B2 Multi-channel time-reversal receivers for multi and 1-bit implementations 有权
标题翻译：用于多和1位实现的多通道时间反转接收器
公开(公告)号：US07463690B2
公开(公告)日：2008-12-09
申请号：US11271334
申请日：2005-11-10
申请人： James V. Candy , David H. Chambers , Brian L. Guidry , Andrew J. Poggio , Christopher L. Robbins
发明人： James V. Candy , David H. Chambers , Brian L. Guidry , Andrew J. Poggio , Christopher L. Robbins
IPC分类号： H04L27/00
CPC分类号： H04L25/0212 , H04L25/0228 , H04L25/0248
摘要： A communication system for transmitting a signal through a channel medium comprising digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. In one embodiment a transmitter is adapted to transmit the signal, a multiplicity of receivers are adapted to receive the signal, a digitizer digitizes the signal, and a time-reversal signal processor is adapted to time-reverse the digitized signal. An embodiment of the present invention includes multi bit implementations. Another embodiment of the present invention includes 1-bit implementations. Another embodiment of the present invention includes a multiplicity of receivers used in the step of transmitting the signal through the channel medium.
摘要翻译：一种用于通过信道介质发送信号的通信系统，包括数字化信号，时间反转数字化信号，以及通过信道介质发送信号。在一个实施例中，发射机适于传输信号，多个接收机适于接收该信号，数字化仪数字化该信号，并且时间反转信号处理器适于对数字化信号进行时间反转。本发明的实施例包括多比特实现。本发明的另一实施例包括1位实现。本发明的另一实施例包括在通过信道介质发送信号的步骤中使用的多个接收机。

3. 发明授权

US06490469B2 Method and apparatus for dynamic focusing of ultrasound energy 失效
标题翻译：超声能量动态聚焦的方法和装置
公开(公告)号：US06490469B2
公开(公告)日：2002-12-03
申请号：US09809961
申请日：2001-03-14
申请人： James V. Candy
发明人： James V. Candy
IPC分类号： A61B500
CPC分类号： A61B17/2258 , A61B5/08 , A61B8/08 , A61B17/22004 , A61B17/2256 , A61B2017/22028 , A61H23/0245 , A61N2007/0078 , G01S7/52046 , G10K11/346
摘要： Method and system disclosed herein include noninvasively detecting, separating and destroying multiple masses (tumors, cysts, etc.) through a plurality of iterations from tissue (e.g., breast tissue). The method and system may open new frontiers with the implication of noninvasive treatment of masses in the biomedical area along with the expanding technology of acoustic surgery.
摘要翻译：本文公开的方法和系统包括通过来自组织（例如，乳腺组织）的多次迭代来非侵入性地检测，分离和破坏多个肿块（肿瘤，囊肿等）。该方法和系统可以开放新的前沿，伴随着声学手术技术的不断扩展，对生物医学领域的群众进行无创处理。

4. 发明申请

US20100030721A1 Physics-Based, Bayesian Sequential Detection Method and System for Radioactive Contraband 有权
标题翻译：基于物理的贝叶斯序列检测方法和放射性对照系统
公开(公告)号：US20100030721A1
公开(公告)日：2010-02-04
申请号：US12259198
申请日：2008-10-27
申请人： James V. Candy , Michael C. Axelrod , Eric F. Breitfeller , David H. Chambers , Brian L. Guidry , Douglas R. Manatt , Alan W. Meyer , Kenneth E. Sale
发明人： James V. Candy , Michael C. Axelrod , Eric F. Breitfeller , David H. Chambers , Brian L. Guidry , Douglas R. Manatt , Alan W. Meyer , Kenneth E. Sale
IPC分类号： G06N5/02
CPC分类号： G06N7/005
摘要： A distributed sequential method and system for detecting and identifying radioactive contraband from highly uncertain (noisy) low-count, radionuclide measurements, i.e. an event mode sequence (EMS), using a statistical approach based on Bayesian inference and physics-model-based signal processing based on the representation of a radionuclide as a monoenergetic decomposition of monoenergetic sources. For a given photon event of the EMS, the appropriate monoenergy processing channel is determined using a confidence interval condition-based discriminator for the energy amplitude and interarrival time. If accepted the parameter values of the photon event are used to update the parameter values using an LKF for the energy amplitude and a bootstrap PF for the interarrival times. These parameter estimates are then used to update a measured probability density function estimate for a target radionuclide. A a sequential likelihood ratio test, which is based in part on a previous sequential likelihood ratio for a previous photon event, the updated measured PDF estimates, and the an a-priori PDF estimates based on expected amplitude level and interarrival time values of the target radionuclide, is then used to determine one of two threshold conditions signifying that the EMS is either identified as the target radionuclide or as not the target radionuclide, and if not, then repeating the process with for the next sequential photon event of the EMS until one of the two threshold conditions is satisfied.
摘要翻译：使用基于贝叶斯推理和基于物理模型的信号处理的统计方法，从高度不确定（噪声）低计数，放射性核素测量（即事件模式序列（EMS））中检测和识别放射性违禁品的分布式顺序方法和系统基于放射性核素作为单能源的单能分解的表示。对于EMS的给定光子事件，使用基于置信区间条件的鉴别器确定适当的单能量处理信道用于能量幅度和间隔时间。如果接受，光子事件的参数值用于使用用于能量幅度的LKF和用于间隔时间的引导PF来更新参数值。然后使用这些参数估计来更新目标放射性核素的测量概率密度函数估计。一种连续似然比测试，其部分地基于先前光子事件的先前顺序似然比，更新的测量的PDF估计和基于目标的预期振幅水平和差异时间值的先验PDF估计放射性核素，然后用于确定两个阈值条件之一，表示EMS被识别为目标放射性核素，或者不是目标放射性核素，如果不是，则重复该过程用于EMS的下一个顺序光子事件直到一个满足两个阈值条件。

5. 发明授权

US07460605B2 Time reversal communication system 有权
标题翻译：时间反转通信系统
公开(公告)号：US07460605B2
公开(公告)日：2008-12-02
申请号：US10289774
申请日：2002-11-06
申请人： James V. Candy , Alan W. Meyer
发明人： James V. Candy , Alan W. Meyer
IPC分类号： H04L27/00
CPC分类号： H04L1/12 , H04B7/0615 , H04L25/0212 , H04L25/0228 , H04L25/0248
摘要： A system of transmitting a signal through a channel medium comprises digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. The channel medium may be air, earth, water, tissue, metal, and/or non-metal.
摘要翻译：通过信道介质发送信号的系统包括数字化信号，对数字信号进行时间反转，以及通过信道介质发送信号。通道介质可以是空气，地球，水，组织，金属和/或非金属。

6. 发明授权

US08676744B2 Physics-based, Bayesian sequential detection method and system for radioactive contraband 有权
标题翻译：基于物理学，贝叶斯序列检测方法和放射性违禁品系统
公开(公告)号：US08676744B2
公开(公告)日：2014-03-18
申请号：US12259198
申请日：2008-10-27
申请人： James V. Candy , Michael C. Axelrod , Eric F. Breitfeller , David H. Chambers , Brian L. Guidry , Douglas R. Manatt , Alan W. Meyer , Kenneth E. Sale
发明人： James V. Candy , Michael C. Axelrod , Eric F. Breitfeller , David H. Chambers , Brian L. Guidry , Douglas R. Manatt , Alan W. Meyer , Kenneth E. Sale
IPC分类号： G06F15/00 , G06F15/18
CPC分类号： G06N7/005
摘要： A distributed sequential method and system for detecting and identifying radioactive contraband from highly uncertain (noisy) low-count, radionuclide measurements, i.e. an event mode sequence (EMS), using a statistical approach based on Bayesian inference and physics-model-based signal processing based on the representation of a radionuclide as a monoenergetic decomposition of monoenergetic sources. For a given photon event of the EMS, the appropriate monoenergy processing channel is determined using a confidence interval condition-based discriminator for the energy amplitude and interarrival time and parameter estimates are used to update a measured probability density function estimate for a target radionuclide. A sequential likelihood ratio test is then used to determine one of two threshold conditions signifying that the EMS is either identified as the target radionuclide or not, and if not, then repeating the process for the next sequential photon event of the EMS until one of the two threshold conditions is satisfied.
摘要翻译：使用基于贝叶斯推理和基于物理模型的信号处理的统计方法，从高度不确定（噪声）低计数，放射性核素测量（即事件模式序列（EMS））中检测和识别放射性违禁品的分布式顺序方法和系统基于放射性核素作为单能源的单能分解的表示。对于EMS的给定光子事件，使用用于能量幅度和差异时间的基于置信区间条件的鉴别器来确定适当的单能量处理信道，并且使用参数估计来更新目标放射性核素的测量的概率密度函数估计。然后使用顺序似然比检验来确定表示EMS被标识为目标放射性核素的两个阈值条件之一，如果不是，则重复EMS的下一个顺序光子事件的处理，直到其中一个满足两个阈值条件。

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