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1. 发明授权

US08027725B2 Capture verification using an evoked response reference 有权
标题翻译：使用诱发响应参考捕获验证
公开(公告)号：US08027725B2
公开(公告)日：2011-09-27
申请号：US12719117
申请日：2010-03-08
申请人： Jaeho Kim , Joseph Bocek
发明人： Jaeho Kim , Joseph Bocek
IPC分类号： A61N1/37 , A61N1/372 , A61B5/04
CPC分类号： A61N1/3712
摘要： A method and system for verifying capture in the heart involves the use of pacing artifact templates. One or more pacing artifact templates characterizing a post pace artifact signal associated with a particular pace voltage or range of voltages are provided. A pacing artifact template is canceled from a cardiac signal sensed following a pacing pulse. Capture is detected by comparing the pacing artifact canceled cardiac signal to an evoked response reference. Fusion/pseudofusion detection involves determining a correlation between a captured response template and a sensed cardiac signal.
摘要翻译：用于验证心脏中捕获的方法和系统涉及使用起搏假象模板。提供了表征与特定步速电压或电压范围相关联的后期假想信号的一个或多个起搏假象模板。从起搏脉冲后检测的心脏信号取消起搏神经模板。通过将起搏神经消除的心脏信号与诱发的反应参考进行比较来检测捕获。融合/伪融合检测涉及确定捕获的响应模板和感测的心脏信号之间的相关性。

2. 发明申请

US20070197928A1 RHYTHM DISCRIMINATION OF SUDDEN ONSET AND ONE-TO-ONE TACHYARRHYTHMIA 失效
标题翻译： SUDDEN ONSET和一对一TACHYARRHYTHMIA的RHYTHM辨别
公开(公告)号：US20070197928A1
公开(公告)日：2007-08-23
申请号：US11276213
申请日：2006-02-17
申请人： Jaeho Kim , Joseph Bocek
发明人： Jaeho Kim , Joseph Bocek
IPC分类号： A61B5/04
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3622 , A61N1/3925 , A61N1/3962 , G06F19/00
摘要： This document discusses, among other things, systems and methods to discriminate between a ventricular tachyarrhythmia (VT) and a supraventricular tachyarrhythmia (SVT), such as upon detecting sudden onset and one-to-one tachycardia. In certain examples, a detected tachyarrhythmia is analyzed to determine whether it is sudden onset and 1:1. If so, a first fast beat is identified. One or more ventricular intervals in close proximity to the first fast beat are analyzed to determine an initial classification of either VT or SVT. The initial classification is used to adjust a morphological feature correlation coefficient (FCC) threshold. A morphology analysis is performed with the adjusted FCC threshold value to yield a secondary classification.
摘要翻译：本文件尤其涉及区分心室性心律失常（VT）和室上性快速性心律失常（SVT）的系统和方法，例如在检测到突发性发作和一对一心动过速时。在某些实例中，分析检测到的快速性心律失常以确定其是否突然发作和1：1。如果是这样，首先确定快节拍。分析紧邻第一快节拍的一个或多个心室间隔以确定VT或SVT的初始分类。初始分类用于调整形态特征相关系数（FCC）阈值。用调整的FCC阈值进行形态分析以产生次级分类。

3. 发明申请

US20050131478A1 Cardiac response classification using multisite sensing and pacing 有权
标题翻译：心脏反应分类采用多站点检测和起搏
公开(公告)号：US20050131478A1
公开(公告)日：2005-06-16
申请号：US10735519
申请日：2003-12-12
申请人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
发明人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
IPC分类号： A61B5/0452 , A61N1/362 , A61N1/37
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/7217 , A61B5/7264 , A61N1/368
摘要： Methods and devices for classifying a cardiac pacing response involve using a first electrode combination for pacing and a second electrode combination for sensing a cardiac signal following pacing. The cardiac response to pacing may be classified using the sensed cardiac signal. One process involves using the sensed cardiac signal to detect the cardiac response as a fusion/pseudofusion beat. Another process involves using the sensed cardiac signal to classify the cardiac response to pacing as one of at least three cardiac response types.
摘要翻译：用于分类心脏起搏反应的方法和装置涉及使用用于起搏的第一电极组合和用于感测起搏后的心脏信号的第二电极组合。可以使用感测到的心脏信号来分类对起搏的心脏反应。一个过程涉及使用感测到的心脏信号来检测作为融合/假融合搏动的心脏反应。另一个过程涉及使用所感测到的心脏信号将心脏起搏应答分为至少三种心脏反应类型之一。

4. 发明申请

US20050131476A1 Cardiac response classification using multiple classification windows 有权
标题翻译：使用多个分类窗口的心脏反应分类
公开(公告)号：US20050131476A1
公开(公告)日：2005-06-16
申请号：US10733869
申请日：2003-12-11
申请人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
发明人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
IPC分类号： A61B5/0452 , A61N1/362 , A61B5/0402 , A61N1/37
CPC分类号： A61B5/7264 , A61B5/04525 , A61B5/7217 , A61N1/371
摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a plurality of classification windows relative to and following a pacing pulse. One or more characteristics of a cardiac signal sensed following the pacing pulse are detected within one or more particular classification windows. The characteristics may be compared to one or more references. Classification of the cardiac response may be performed based on the comparison of the one or more characteristics to the one or more references and the particular classification windows in which the one or more characteristics are detected.
摘要翻译：用于将心脏反应分类到起搏的方法和装置涉及建立相对于起搏脉冲和起搏脉冲之后的多个分类窗口。在一个或多个特定分类窗口中检测到在起搏脉冲之后感测的心脏信号的一个或多个特征。特征可以与一个或多个参考进行比较。心脏反应的分类可以基于一个或多个特征与一个或多个参考和检测到一个或多个特征的特定分类窗口的比较来执行。

5. 发明授权

US06889079B2 Method and system for characterizing supraventricular rhythm during cardiac pacing 有权
标题翻译：在心脏起搏期间表现室上节律的方法和系统
公开(公告)号：US06889079B2
公开(公告)日：2005-05-03
申请号：US10121944
申请日：2002-04-12
申请人： Joseph Bocek , Jaeho Kim , Anthony Harrington
发明人： Joseph Bocek , Jaeho Kim , Anthony Harrington
IPC分类号： A61N1/362
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.
摘要翻译：用于产生患者室上性节律（SVR）的一搏的表征的方法和系统涉及在心脏起搏时进行这种表征。在SVR表征期间，修改了各种起搏参数，并对患者的室上节律进行了表征，同时对起搏参数进行了修改。 SVR表征过程在单腔和多腔起搏模式中有效。

6. 发明授权

US08831726B2 Cardiac response classification using multiple classification windows 有权
标题翻译：使用多个分类窗口的心脏反应分类
公开(公告)号：US08831726B2
公开(公告)日：2014-09-09
申请号：US12008876
申请日：2008-01-15
申请人： Jaeho Kim , Joseph Bocek , Scott A. Meyer , Paul A. Haefner , Haris J. Sih
发明人： Jaeho Kim , Joseph Bocek , Scott A. Meyer , Paul A. Haefner , Haris J. Sih
IPC分类号： A61B5/0452 , A61B5/00 , A61N1/37
CPC分类号： A61B5/7264 , A61B5/04525 , A61B5/7217 , A61N1/371
摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a plurality of classification windows relative to and following a pacing pulse. One or more characteristics of a cardiac signal sensed following the pacing pulse are detected within one or more particular classification windows. The characteristics may be compared to one or more references. Classification of the cardiac response may be performed based on the comparison of the one or more characteristics to the one or more references and the particular classification windows in which the one or more characteristics are detected.
摘要翻译：用于将心脏反应分类为起搏的方法和装置涉及建立相对于起搏脉冲和起搏脉冲之后的多个分类窗口。在一个或多个特定分类窗口中检测到在起搏脉冲之后感测的心脏信号的一个或多个特征。特征可以与一个或多个参考进行比较。心脏反应的分类可以基于一个或多个特征与一个或多个参考和检测到一个或多个特征的特定分类窗口的比较来执行。

7. 发明授权

US08417335B2 Synchronized ventricular pacing to promote atrial sensing 失效
公开(公告)号：US08417335B2
公开(公告)日：2013-04-09
申请号：US12539167
申请日：2009-08-11
申请人： Jaeho Kim , Joseph Bocek , Anthony Harrington
发明人： Jaeho Kim , Joseph Bocek , Anthony Harrington
IPC分类号： A61N1/39
CPC分类号： A61N1/3622 , A61N1/3682
摘要： Methods and systems are described that involve synchronized ventricular pacing that promotes sensing of atrial events. The atrioventricular pacing delay is modified based on characteristics of previously sensed atrial events. The modified AV delay is implemented relative to a first atrial event. A second AV delay is implemented relative to a second atrial event if the second atrial event is sensed during the modified AV delay. A ventricular pacing pulse is delivered following the second AV delay.

8. 发明授权

US08185195B2 Arrhythmia classification and therapy selection 失效
标题翻译：心律失常分类与治疗选择
公开(公告)号：US08185195B2
公开(公告)日：2012-05-22
申请号：US12708106
申请日：2010-02-18
申请人： Jaeho Kim , Joseph Bocek , Eric G. Lovett
发明人： Jaeho Kim , Joseph Bocek , Eric G. Lovett
IPC分类号： A61N1/36
CPC分类号： A61B5/7264 , A61B5/04525
摘要： Different types of cardiac arrhythmia are classified based on the morphology of the arrhythmic beats. Cardiac beats associated with an arrhythmic episode are compared to a plurality of representative beat morphologies, each representative beat morphology characterizing a type of arrhythmia of the heart. An arrhythmic episode may be classified as a particular type of arrhythmia if the morphology of the arrhythmic cardiac beats matches a representative beat morphology characterizing the particular type of arrhythmia. An appropriate therapy for the particular type of arrhythmia may be selected based on the arrhythmia classification. A particular type of arrhythmia may be associated with one or more therapies used to treat the arrhythmia. The therapy used to treat the arrhythmia may comprise a therapy identified as a previously successful therapy.
摘要翻译：基于心律失常节律的形态分类不同类型的心律失常。与心律失常发作相关的心脏搏动与多个代表性搏动形态进行比较，每个代表性搏动形态表征心脏心律失常的类型。如果心律失常心跳的形态与表征特定类型的心律失常的代表性搏动形态匹配，则心律失常发作可被分类为特定类型的心律失常。可以基于心律失常分类来选择针对特定类型的心律失常的适当疗法。特定类型的心律失常可能与用于治疗心律失常的一种或多种治疗相关联。用于治疗心律失常的治疗可以包括被确定为先前成功的治疗的治疗。

9. 发明申请

US20120065696A1 Method and System for Characterizing Supraventricular Rhythm during Cardiac Pacing 有权
标题翻译：心脏起搏过程中表现室性节律的方法与系统
公开(公告)号：US20120065696A1
公开(公告)日：2012-03-15
申请号：US13159686
申请日：2011-06-14
申请人： Joseph Bocek , Jaeho Kim , Anthony S. Harrington , Lorenzo A. DiCarlo , Harley G. White , Phillip D. Foshee , David L. Perschbacher
发明人： Joseph Bocek , Jaeho Kim , Anthony S. Harrington , Lorenzo A. DiCarlo , Harley G. White , Phillip D. Foshee , David L. Perschbacher
IPC分类号： A61N1/365
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.
摘要翻译：用于产生患者室上性节律（SVR）的一搏的表征的方法和系统涉及在心脏起搏时进行这种表征。在SVR表征期间，修改了各种起搏参数，并对患者的室上节律进行了表征，同时对起搏参数进行了修改。 SVR表征过程在单腔和多腔起搏模式中有效。

10. 发明授权

US08041425B2 Atrial tachyarrhythmia detection using selected atrial intervals 失效
标题翻译：使用选择的心房间隔进行心房快速性心律失常检测
公开(公告)号：US08041425B2
公开(公告)日：2011-10-18
申请号：US12538294
申请日：2009-08-10
申请人： Jaeho Kim , Joseph Bocek , Anthony Harrington , Harley White
发明人： Jaeho Kim , Joseph Bocek , Anthony Harrington , Harley White
IPC分类号： A61B1/00
CPC分类号： A61N1/3702 , A61B5/0464 , A61N1/3622
摘要： Methods and systems are directed to detecting atrial tachyarrhythmia. A plurality of A-A intervals is detected. The detected A-A intervals are selected and used to detect atrial tachyarrhythmia. Selecting A-A intervals may be based on determining that A-A intervals are qualified. Qualified A-A intervals may be determined if a duration of the particular A-A interval falls outside a predetermined duration range, for example. Qualified A-A intervals may also be determined based on events occurring between consecutively sensed atrial events of the particular A-A interval, and whether the duration of the particular A-A interval falls within the predetermined duration range, for example.
摘要翻译：方法和系统旨在检测房性快速性心律失常。检测到多个A-A间隔。检测到的A-A间隔被选择并用于检测房性快速性心律失常。选择A-A间隔可以基于确定A-A间隔是合格的。例如，如果特定A-A间隔的持续时间落在预定的持续时间范围之外，则可以确定合格的A-A间隔。也可以基于特定A-A间隔的连续感测的心房事件之间发生的事件以及特定A-A间隔的持续时间是否落入预定持续时间范围内来确定合格的A-A间隔。

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