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1. 发明授权

US07799049B2 Atraumatic anchoring and disengagement mechanism for permanent implant device 失效
标题翻译：永久植入装置的无创锚固和脱离机制
公开(公告)号：US07799049B2
公开(公告)日：2010-09-21
申请号：US10155367
申请日：2002-05-23
申请人： Isaac Ostrovsky , Michael J. Wallace , Hannah Kim , Peter Shank , Kristian DiMatteo
发明人： Isaac Ostrovsky , Michael J. Wallace , Hannah Kim , Peter Shank , Kristian DiMatteo
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2002/8486 , A61F2230/005 , A61F2230/0067
摘要： A recoverable thrombosis filter that may be recoverable by a single recovery procedure. It can include a plurality of thrombosis filtering elements that are shaped in a predetermined manner and which are joined at one end and are deployed about a longitudinal axis to form a generally conical structure. The filtering elements can include shaped ends for engaging an inner lumen wall.
摘要翻译：可恢复的血栓形成过滤器，可以通过单次恢复手术恢复。它可以包括多个血栓形成过滤元件，其以预定方式成形并且在一端连接并围绕纵向轴线展开以形成大致圆锥形的结构。过滤元件可以包括用于接合内腔壁的成形端。

2. 发明授权

US06447530B1 Atraumatic anchoring and disengagement mechanism for permanent implant device 失效
公开(公告)号：US06447530B1
公开(公告)日：2002-09-10
申请号：US08978403
申请日：1997-11-25
申请人： Isaac Ostrovsky , Michael J. Wallace , Hannah Kim , Peter Shank , Kristian DiMatteo
发明人： Isaac Ostrovsky , Michael J. Wallace , Hannah Kim , Peter Shank , Kristian DiMatteo
IPC分类号： A61M2900
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2002/8486 , A61F2230/005 , A61F2230/0067
摘要： A recoverable thrombosis filter that can be implanted and securely positioned within a vein at a desired location, and can be recovered through an endovenous route even after formation of neointima hyperplasia, is disclosed.

3. 发明授权

US07947070B2 Dilatation and stent delivery system and related methods 有权
公开(公告)号：US07947070B2
公开(公告)日：2011-05-24
申请号：US10439298
申请日：2003-05-16
申请人： F. Anthony Headley , Peter Shank , Emily Rusk , John Damarati , Michael Abi-Kheirs
发明人： F. Anthony Headley , Peter Shank , Emily Rusk , John Damarati , Michael Abi-Kheirs
IPC分类号： A61F2/06 , A61F11/00
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9517
摘要： The invention relates to a system for dilatation of a body passage and delivery of a stent into the body passage of a patient, and related methods of using such a system. The dilatation and stent delivery system may comprise a dilatation catheter having an expandable member on a distal end, and a stent delivery catheter configured to retain a stent and deliver the stent to a body passage. The stent delivery catheter defines a lumen sized to receive the dilatation catheter and permit movement of the dilatation catheter relative to the stent delivery catheter.

4. 发明申请

US20050113904A1 Composite stent with inner and outer stent elements and method of using the same 审中-公开
标题翻译：具有内外支架元件的复合支架及其使用方法
公开(公告)号：US20050113904A1
公开(公告)日：2005-05-26
申请号：US10720176
申请日：2003-11-25
申请人： Peter Shank , F. Headley
发明人： Peter Shank , F. Headley
IPC分类号： A61F2/00 , A61F2/86 , A61F2/06
CPC分类号： A61F2/86 , A61F2/07 , A61F2/90 , A61F2002/075 , A61F2220/0016 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0078 , A61F2250/0067
摘要： A composite stent structure includes separate and distinct stent elements or members: an outer stent element and an inner stent element removably attached to the outer stent element. The outer element may be, for example, a bioabsorbable stent typically constructed of a relatively non-resilient material such that the outer bioabsorbable stent element may not be self-expanding and subject to migration within the lumen over time. In contrast, the inner element may be, for example, a removable SEMS used to urge and maintain the outer element in position in the body lumen. The temporary inner SEMS may retain the composite structure (including the underlying inner element) in position until such time as the outer element is appropriately incorporated into the surrounding tissue or some other criteria occurs such that the removal of the SEMS is indicated. The SEMS may then be detached from the outer element and removed from the body lumen.
摘要翻译：复合支架结构包括分开且不同的支架元件或构件：外支架元件和可移除地附接到外支架元件的内支架元件。外部元件可以是例如通常由相对非弹性材料构成的生物可吸收支架，使得外部生物可吸收支架元件可能不会自我扩张并且随着时间内在腔内迁移。相反，内部元件可以是例如用于将外部元件推动并保持在体腔内的适当位置的可移除的SEMS。临时内部SEMS可以将复合结构（包括下面的内部元件）保持在适当位置，直到外部元件适当地结合到周围组织中或者出现一些其它标准，以便指出移除SEMS。然后可以将SEMS从外部元件分离并从体腔中移出。

5. 发明授权

US09265596B2 Anchors with open heads 有权
标题翻译：有开头的锚
公开(公告)号：US09265596B2
公开(公告)日：2016-02-23
申请号：US13394975
申请日：2010-09-10
申请人： Peter Shank , David A. Melanson , Barry Maxwell , Sean K. Holmes , James Loper , Ian K. Parker , Andy H. Levine
发明人： Peter Shank , David A. Melanson , Barry Maxwell , Sean K. Holmes , James Loper , Ian K. Parker , Andy H. Levine
IPC分类号： A61M5/00 , A61F2/04 , A61F5/00 , A61F2/06 , A61F2/24 , A61F2/848
CPC分类号： A61F2/04 , A61F2/2409 , A61F2/848 , A61F5/0076 , A61F5/0089 , A61F2002/045 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2230/0091 , A61F2250/0031
摘要： An implant (100) includes a protrusion (110) with an open or rounded loop (112) (or open head) connected to a collapsible anchor. The protrusion may include a straight length of wire (114) or a helical length wire, with one or more wire loops (112) at the end of the length forming the loop. Upon deployment within the gastrointestinal tract, the protrusion expands from a collapsed state, alongside the anchor, to a relaxed state, in which the protrusion extends outward from the anchor. As the protrusion expands to its relaxed state, it pushes the loop into the wall of the duodenum, causing the loop to penetrate the duodenal wall. A pocket of scar tissue forms about the head and possibly through an opening in the head, securing the anchor within the duodenum. The implant may also include a thin-walled sleeve that is coupled to the anchor and extended from the anchor into the intestine.
摘要翻译：植入物（100）包括具有连接到可折叠锚的开放或圆形回路（112）（或开放头）的突起（110）。突起可以包括直线长度的线（114）或螺旋长度线，其中一个或多个线环（112）在长度的端部形成环。在胃肠道内展开时，突起从锚固体的折叠状态膨胀到松弛状态，其中突起从锚向外延伸。当突起膨胀到其松弛状态时，它将环推入十二指肠的壁中，导致环穿透十二指肠壁。疤痕组织的口袋形成在头部周围并且可能通过头部中的开口，将锚固件固定在十二指肠内。植入物还可以包括薄壁套筒，其耦合到锚固件并从锚固件延伸到肠中。

6. 发明申请

US20070055352A1 Stent with pockets for containing a therapeutic agent 审中-公开
标题翻译：支架用于含有治疗剂
公开(公告)号：US20070055352A1
公开(公告)日：2007-03-08
申请号：US11221647
申请日：2005-09-07
申请人： Wendy Naimark , Peter Shank , Maria Palasis , Toby Freyman , Anastasia Panos , Samuel Epstein , Alexandra Rousseau
发明人： Wendy Naimark , Peter Shank , Maria Palasis , Toby Freyman , Anastasia Panos , Samuel Epstein , Alexandra Rousseau
IPC分类号： A61F2/90
CPC分类号： A61L31/16 , A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2220/0008 , A61F2230/0013 , A61F2250/0068 , A61L2300/606
摘要： A medical device for: delivering a therapeutic agent to a body lumen is described. The device may generally be a stent with an inner sidewall surface and an outer sidewall surface, with a plurality of struts having a plurality of openings therein. An inner and outer layer may be applied to the stent, forming pockets within at least a portion of the openings. The pockets may be filled with at least one therapeutic agent. The pockets may take a variety of shapes and sizes, and may be designed for release or rupture in variety of ways.
摘要翻译：描述了用于将治疗剂递送到体腔的医疗装置。该装置通常可以是具有内侧壁表面和外侧壁表面的支架，多个支柱在其中具有多个开口。内层和外层可以施加到支架上，在开口的至少一部分内形成袋。口袋可以填充有至少一种治疗剂。口袋可以采取各种形状和尺寸，并且可以设计为以各种方式释放或破裂。

7. 发明授权

US08668728B2 Dilatation and stent delivery system and related methods 有权
公开(公告)号：US08668728B2
公开(公告)日：2014-03-11
申请号：US13107229
申请日：2011-05-13
申请人： F. Anthony Headley , Peter Shank , Emily Rusk , John Damarati , Michael Abi-Kheirs
发明人： F. Anthony Headley , Peter Shank , Emily Rusk , John Damarati , Michael Abi-Kheirs
IPC分类号： A61F2/06 , A61F11/00
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9517
摘要： The invention relates to a system for dilatation of a body passage and delivery of a stent into the body passage of a patient, and related methods of using such a system. The dilatation and stent delivery system may comprise a dilatation catheter having an expandable member on a distal end, and a stent delivery catheter configured to retain a stent and deliver the stent to a body passage. The stent delivery catheter defines a lumen sized to receive the dilatation catheter and permit movement of the dilatation catheter relative to the stent delivery catheter.

8. 发明申请

US20120179086A1 ANCHORS WITH OPEN HEADS 有权
标题翻译：带开头的锚杆
公开(公告)号：US20120179086A1
公开(公告)日：2012-07-12
申请号：US13394975
申请日：2010-09-10
申请人： Peter Shank , David A. Melanson , Barry Maxwell , Sean K. Holmes , James Loper , Ian K. Parker , Andy H. Levine
发明人： Peter Shank , David A. Melanson , Barry Maxwell , Sean K. Holmes , James Loper , Ian K. Parker , Andy H. Levine
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61F2/2409 , A61F2/848 , A61F5/0076 , A61F5/0089 , A61F2002/045 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2230/0091 , A61F2250/0031
摘要： An implant (100) includes a protrusion (110) with an open or rounded loop (112) (or open head) connected to a collapsible anchor. The protrusion may include a straight length of wire (114) or a helical length wire, with one or more wire loops (112) at the end of the length forming the loop. Upon deployment within the gastrointestinal tract, the protrusion expands from a collapsed state, alongside the anchor, to a relaxed state, in which the protrusion extends outward from the anchor. As the protrusion expands to its relaxed state, it pushes the loop into the wall of the duodenum, causing the loop to penetrate the duodenal wall. A pocket of scar tissue forms about the head and possibly through an opening in the head, securing the anchor within the duodenum. The implant may also include a thin-walled sleeve that is coupled to the anchor and extended from the anchor into the intestine.
摘要翻译：植入物（100）包括具有连接到可折叠锚的开放或圆形回路（112）（或开放头）的突起（110）。突起可以包括直线长度的线（114）或螺旋长度线，其中一个或多个线环（112）在长度的端部形成环。在胃肠道内展开时，突起从锚固体的折叠状态膨胀到松弛状态，其中突起从锚向外延伸。当突起膨胀到其松弛状态时，它将环推入十二指肠的壁中，导致环穿透十二指肠壁。疤痕组织的口袋形成在头部周围并且可能通过头部中的开口，将锚固件固定在十二指肠内。植入物还可以包括薄壁套筒，其耦合到锚固件并从锚固件延伸到肠中。

9. 发明授权

US08834553B2 Anchors with biodegradable constraints 有权
标题翻译：具有可生物降解约束的锚点
公开(公告)号：US08834553B2
公开(公告)日：2014-09-16
申请号：US13045363
申请日：2011-03-10
申请人： David A. Melanson , Christopher Nutting , Barry Maxwell , Peter Shank , John Panek
发明人： David A. Melanson , Christopher Nutting , Barry Maxwell , Peter Shank , John Panek
IPC分类号： A61F2/06 , A61F2/04 , A61F5/00 , A61F2/848
CPC分类号： A61F5/0076 , A61F2/04 , A61F2002/045 , A61F2002/8483 , A61F2220/0016 , A61F2250/0031
摘要： An implant includes a collapsible anchor to be deployed within a lumen and a protrusion coupled to the anchor. The protrusion, in a constrained state, extends a distance from an exterior surface of the anchor and, in an unconstrained state, extends further from the exterior surface of the anchor. Also included is a biodegradable constraint, such as a biodegradable tube or suture, configured to maintain the protrusion in the constrained state until the constraint releases. The implant may include additional biodegradable constraints, each constraint configured to maintain the protrusion in a different constrained state and to degrade over a different predetermined period after the implant has been deployed within the lumen. The protrusion may include a bi-directional barb or an open loop. The protrusion may be configured to penetrate a wall of the lumen and to allow tissue to grow about the protrusion. The implant may also include an unsupported, thin-walled sleeve coupled to the anchor and configured to extend into the lumen upon deployment of the collapsible anchor.
摘要翻译：植入物包括待部署在内腔内的可折叠锚固件和联接到锚固件的突出部。处于受约束状态的突起从锚的外表面延伸一段距离，并且在非约束状态下从锚的外表面进一步延伸。还包括可生物降解的约束，例如可生物降解的管或缝合线，其被配置为将突起保持在约束状态直到约束释放。植入物可以包括额外的可生物降解的约束，每个约束被配置为将突起保持在不同的约束状态，并且在植入物已经在内腔中展开之后在不同的预定时间段内降解。突起可以包括双向倒钩或开环。突出部可以构造成穿过内腔的壁并允许组织围绕突起生长。植入物还可以包括未支撑的薄壁套筒，其联接到锚固件并且构造成在展开可折叠锚固件时延伸到内腔中。

10. 发明申请

US20090171434A1 PROSTHESIS LOADING DELIVERY AND DEPLOYMENT APPARATUS 审中-公开
标题翻译： PROSTHESIS加载交付和部署设备
公开(公告)号：US20090171434A1
公开(公告)日：2009-07-02
申请号：US12336596
申请日：2008-12-17
申请人： Emily Rusk , Peter Shank , Michael Abi-Kheirs
发明人： Emily Rusk , Peter Shank , Michael Abi-Kheirs
IPC分类号： A61F2/06 , A61B19/00
CPC分类号： A61F2/95 , A61F2002/9522
摘要： Prosthesis loading and deploying systems include a capturing device with a proximal stent-engaging member and an elongate pulling member extending distally from the stent-engaging member. With a prosthesis or stent in a relaxed or enlarged-radius state, the pulling member is guided distally through a delivery catheter, pulling the stent-engaging member and prosthesis into the catheter lumen to progressively radially compress the prosthesis to a reduced-radius state. Simultaneously the distal end region of an elongate control device is maintained within a proximal region of the prosthesis, so that the prosthesis is compressed about the control device distal end region as these components enter the catheter. When the prosthesis is compressed about the control device, it tends to follow axial movement of the control device, thus to afford reliable positional control of the prosthesis inside the catheter by manipulating the control device.
摘要翻译：假体装载和展开系统包括具有近端支架接合构件的捕获装置和从支架接合构件向远侧延伸的细长牵引构件。通过假体或支架处于松弛或扩大的半径状态，拉动构件被向远侧引导通过输送导管，将支架接合构件和假体拉入导管内腔，以将假体逐渐径向压缩至缩径半径状态。同时，细长控制装置的远端区域保持在假体的近侧区域内，使得假体在这些部件进入导管时围绕控制装置远端区域被压缩。当假体围绕控制装置被压缩时，其倾向于跟随控制装置的轴向移动，从而通过操纵控制装置来提供对导管内的假体的可靠的位置控制。

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