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1. 发明申请

WO2021242633A1 SINGLE OR MULTIPLE NERVE STIMULATION TO TREAT SLEEP DISORDERED BREATHING 审中-公开
公开(公告)号：WO2021242633A1
公开(公告)日：2021-12-02
申请号：PCT/US2021/033639
申请日：2021-05-21
申请人： INSPIRE MEDICAL SYSTEMS, INC.
发明人： VERZAL, Kevin , HERBERT, Timothy , TESFAYESUS, Wondimeneh , RONDONI, John , NI, Quan
IPC分类号： A61N1/05 , A61N1/36 , A61B5/00
摘要： Devices and/or methods for treating sleep disordered breathing may include stimulation of a single nerve, multiple nerves, as well as other tissues relating to upper airway patency.

2. 发明申请

WO2016149344A1 STIMULATION FOR TREATING SLEEP DISORDERED BREATHING 审中-公开
标题翻译：用于治疗睡眠障碍性呼吸的刺激
公开(公告)号：WO2016149344A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022611
申请日：2016-03-16
申请人： INSPIRE MEDICAL SYSTEMS, INC.
发明人： WAGNER, Darrell , NI, Quan , RONDONI, John , DIEKEN, Dave
IPC分类号： A61N1/36 , A61B5/08 , A61B5/00
CPC分类号： A61N1/3601 , A61B5/0205 , A61B5/0816 , A61B5/0826 , A61B5/113 , A61B5/4818 , A61B5/4848 , A61B5/686 , A61N1/3611 , A61N1/36135 , A61N1/36146 , A61N1/36171 , G06F19/3481
摘要： A device for treating sleep disordered breathing includes a stimulation element to stimulate an airway-patency-related nerve.
摘要翻译：用于治疗睡眠呼吸紊乱的装置包括刺激气道通畅相关神经的刺激元件。

3. 发明申请

WO2015021348A2 PATIENT CONTROL FOR IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗设备的患者控制
公开(公告)号：WO2015021348A2
公开(公告)日：2015-02-12
申请号：PCT/US2014/050272
申请日：2014-08-08
申请人： INSPIRE MEDICAL SYSTEMS, INC.
发明人： RONDONI, John , JOHNSON, Blake D. , NI, Quan
IPC分类号： A61N1/372
CPC分类号： A61N1/3611 , A61B5/0022 , A61B5/0031 , A61B5/4818 , A61B5/4836 , A61N1/36139 , A61N1/37211 , A61N1/37217 , A61N1/37247
摘要： A patient control is disclosed that facilitates operation of an implantable medical device.
摘要翻译：公开了一种便于操作可植入医疗设备的患者控制装置。

4. 发明申请

WO2010117810A1 PERCUTANEOUS ACCESS FOR SYSTEMS OF TREATING SLEEP-RELATED DISORDERED BREATHING 审中-公开
标题翻译：治疗与睡眠相关的疾病呼吸系统的PERCUTANEOUS ACCESS
公开(公告)号：WO2010117810A1
公开(公告)日：2010-10-14
申请号：PCT/US2010/029253
申请日：2010-03-30
申请人： INSPIRE MEDICAL SYSTEMS, INC. , CHRISTOPHERSON, Mark A. , NI, Quan , RONDONI, John
发明人： CHRISTOPHERSON, Mark A. , NI, Quan , RONDONI, John
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/3601 , A61B5/0492 , A61B5/0826 , A61B5/4818 , A61B17/3468 , A61B2090/062 , A61N1/0504 , A61N1/0551 , A61N1/0553 , A61N1/0556 , A61N1/0558
摘要： Systems and methods are described and illustrated for percutaneously implanting a stimulation lead for treating sleep-related disordered breathing.
摘要翻译：描述和说明了用于经皮植入用于治疗与睡眠相关的无序呼吸的刺激引线的系统和方法。

5. 发明申请

WO2010039853A1 TRANSVENOUS METHOD OF TREATING SLEEP APNEA 审中-公开
标题翻译：处理睡眠APNEA的多维方法
公开(公告)号：WO2010039853A1
公开(公告)日：2010-04-08
申请号：PCT/US2009/059060
申请日：2009-09-30
申请人： INSPIRE MEDICAL SYSTEMS, INC. , NI, Quan , CHRISTOPHERSON, Mark A. , HERBERT, Timothy P. , RONDONI, John
发明人： NI, Quan , CHRISTOPHERSON, Mark A. , HERBERT, Timothy P. , RONDONI, John
IPC分类号： A61N1/36 , A61N1/372 , A61F2/82
CPC分类号： A61N1/3601 , A61B5/4818 , A61F2/848 , A61F2/86 , A61N1/37205
摘要： A system and method for treating sleep apnea includes inserting an implantable pulse generator subcutaneously within a body of a patient and connecting a lead to the pulse generator. The lead is inserted within the vasculature and advanced transvenously through the vasculature until a stimulation portion of the lead becomes positioned in close proximity to the hypoglossal nerve. A nerve-stimulation signal is applied to the hypoglossal nerve via the stimulation portion of the lead.
摘要翻译：用于治疗睡眠呼吸暂停的系统和方法包括将可植入脉冲发生器皮下插入患者体内并将引线连接到脉冲发生器。铅被插入脉管系统中，并且通过脉管系统递送，直到引线的刺激部分定位在舌下神经附近。神经刺激信号通过铅的刺激部分施加到舌下神经。

6. 发明申请

WO2022246320A1 MULTIPLE TARGET STIMULATION THERAPY FOR SLEEP DISORDERED BREATHING 审中-公开
公开(公告)号：WO2022246320A1
公开(公告)日：2022-11-24
申请号：PCT/US2022/030543
申请日：2022-05-23
申请人： INSPIRE MEDICAL SYSTEMS, INC.
发明人： VERZAL, Kevin , HERBERT, Timothy , TESFAYESUS, Wondimeneh , RONDONI, John , NI, Quan , LEE, Kent
IPC分类号： A61N1/372 , A61B5/08
摘要： Devices and/or methods for treating sleep disordered breathing may include stimulation of a single nerve, multiple nerves, as well as other tissues relating to upper airway patency.

7. 发明申请

WO2017184753A1 ACCELEROMETER-BASED SENSING FOR SLEEP DISORDERED BREATHING (SDB) CARE 审中-公开
标题翻译：基于加速度计的睡眠呼吸障碍（SDB）护理
公开(公告)号：WO2017184753A1
公开(公告)日：2017-10-26
申请号：PCT/US2017/028391
申请日：2017-04-19
申请人： INSPIRE MEDICAL SYSTEMS, INC.
发明人： DIEKEN, Dave , VERZAL, Kevin , RONDONI, John , NI, Quan , WAGNER, Darrell , THORP, Chris , VILLASENSOR, Everardo , HEDIN, Michael , MOSKOVITZ, Nicole
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61B5/02405 , A61B5/0538 , A61B5/0816 , A61B5/1102 , A61B5/1116 , A61B5/4818 , A61B2562/0219 , A61N1/3611 , A61N1/3752
摘要： A first sensing element including an accelerometer-based sensor for sleep disordered breathing (SDB) care.
摘要翻译：包括用于睡眠呼吸障碍（SDB）护理的基于加速度计的传感器的第一传感元件。

8. 发明申请

WO2013023218A1 SYSTEM FOR SELECTING A STIMULATION PROTOCOL BASED ON SENSED RESPIRATORY EFFORT 审中-公开
标题翻译：基于感觉呼吸作用选择刺激方案的系统
公开(公告)号：WO2013023218A1
公开(公告)日：2013-02-14
申请号：PCT/US2012/050615
申请日：2012-08-13
申请人： INSPIRE MEDICAL SYSTEMS, INC. , NI, Quan , CHRISTOPHERSON, Mark A. , RONDONI, John
发明人： NI, Quan , CHRISTOPHERSON, Mark A. , RONDONI, John
IPC分类号： A61N1/36 , A61B5/08
CPC分类号： A61N1/36139 , A61B5/0402 , A61B5/053 , A61B5/08 , A61B5/0826 , A61B5/085 , A61B5/087 , A61B5/4836 , A61B5/686 , A61B2562/0247 , A61N1/0556 , A61N1/3611
摘要： A stimulation protocol determination system (74) includes an input module (76) and a selector module (78). The input module is provided to receive an indication of an upper airway flow limitation via sensed respiratory effort (82) information. The selection module is provided to automatically select, based on the indicated upper airway flow limitation, a stimulation protocol (86).
摘要翻译：刺激协议确定系统（74）包括输入模块（76）和选择器模块（78）。输入模块被提供以通过感测的呼吸力（82）信息接收上呼吸道流量限制的指示。提供选择模块以根据指示的上呼吸道流量限制自动选择刺激方案（86）。

9. 发明申请

WO2009140636A3 METHOD AND APPARATUS FOR SENSING RESPIRATORY PRESSURE IN AN IMPLANTABLE STIMULATION SYSTEM 审中-公开
公开(公告)号：WO2009140636A3
公开(公告)日：2009-11-19
申请号：PCT/US2009/044207
申请日：2009-05-15
申请人： INSPIRE MEDICAL SYSTEMS, INC. , CHRISTOPHERSON, Mark , HERBERT, Timothy , NI, Quan
发明人： CHRISTOPHERSON, Mark , HERBERT, Timothy , NI, Quan
IPC分类号： A61N1/36 , A61B5/113
摘要： A method and system for sensing respiration in the treatment of sleep apnea is disclosed.

10. 发明申请

WO2016168119A1 SYSTEM AND METHOD OF MONITORING FOR AND REPORTING ON PATIENT-MADE STIMULATION THERAPY PROGRAMMING CHANGES 审中-公开
标题翻译：监测和报告患者制剂治疗方案的系统和方法编程变更
公开(公告)号：WO2016168119A1
公开(公告)日：2016-10-20
申请号：PCT/US2016/026954
申请日：2016-04-11
申请人： INSPIRE MEDICAL SYSTEMS, INC.
发明人： RONDONI, John , NI, Quan
IPC分类号： A61N1/372
CPC分类号： A61N1/37264 , A61N1/37217 , A61N1/37247
摘要： A programmer is configured to effect communication with, and programming of, an implantable medical device configured to deliver neurostimulation therapy. The programmer comprises a display, such as touch screen display, and a processor comprising memory and coupled to the display. An interface is coupled to the processor and configured to receive therapy settings data indicative of current therapy settings operative in the implantable medical device and any modifications made to the therapy settings by a patient. The processor is configured to determine if one or more therapy settings have been modified since the last interaction with the patient, and coordinate displaying of the current therapy settings, the one or more therapy settings modified by the patient, and a previous state of the one or more therapy settings modified by the patient on the display.
摘要翻译：编程器被配置为实现与被配置为递送神经刺激疗法的可植入医疗装置的通信和编程。编程器包括诸如触摸屏显示器的显示器和包括存储器并且耦合到显示器的处理器。接口耦合到处理器并且被配置为接收指示在可植入医疗设备中操作的当前治疗设置的治疗设置数据以及由患者对治疗设置进行的任何修改。处理器被配置为确定自上次与患者的相互作用以来是否修改了一个或多个治疗设置，并且协调当前治疗设置的显示，由患者修改的一个或多个治疗设置以及该患者的先前状态或更多由患者在显示器上修改的治疗设置。

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