专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070122441A1 Biocidal surfaces, articles with biocidal surface agents and methods of synthesizing and evaluating biocidal surface agents 审中-公开
标题翻译：杀生物表面，具有杀生物表面活性剂的制品和合成和评估杀生物剂的方法
公开(公告)号：US20070122441A1
公开(公告)日：2007-05-31
申请号：US11601949
申请日：2006-11-20
申请人： Hironobu Murata , Richard Koespel , Sang Lee , Alan Russell
发明人： Hironobu Murata , Richard Koespel , Sang Lee , Alan Russell
IPC分类号： A01N57/00 , A01N25/00
CPC分类号： A01N25/34 , A01N33/12 , A01N37/36 , A01N43/40 , A01N55/00
摘要： A biocidal article, includes a surface including a plurality of polymers covalently attached to the surface. The polymers include biocidal cationic groups. The polymers have a molecular weight distribution or polydispersity less than 3. A grafting density of the polymers on the surface is controlled, average degree of polymerization of the polymers is controlled and repeat units of the polymers are chosen to provide a predetermined charge density arising from the cationic groups. A method of analyzing biocidal activity of biocidal surface agents includes the steps: attaching a plurality of chemical entities to one or more surfaces so that at least one physiochemical property is varied, each of the chemical entities comprising at least one biocidally active component; and exposing the chemical entities to at least one biological agent to determine the effect of the at least one physiochemical property upon biocidal activity. The biocidal activity can, for example, be antibacterial activity or sporicidal activity. The at least one physiochemical property can, for example, be varied in a preferably systematic manner.
摘要翻译：杀生物制品包括包含共价连接在表面上的多个聚合物的表面。聚合物包括杀生物阳离子基团。聚合物具有小于3的分子量分布或多分散性。控制聚合物在表面上的接枝密度，控制聚合物的平均聚合度，并且选择聚合物的重复单元以提供由阳离子基团。分析杀生物表面活性剂的杀生物活性的方法包括以下步骤：将多个化学实体连接到一个或多个表面，使得至少一个理化特性变化，每个化学实体包含至少一种生物活性成分; 以及将所述化学实体暴露于至少一种生物试剂以确定所述至少一种理化化学性质对杀生物活性的影响。杀生物活性可以例如是抗菌活性或杀孢子活性。至少一种理化特性可以例如以优选系统的方式变化。

2. 发明申请

US20130058910A1 DECONTAMINATION OF CHEMICAL AND BIOLOGICAL AGENTS 审中-公开
标题翻译：化学和生物代谢物的去除
公开(公告)号：US20130058910A1
公开(公告)日：2013-03-07
申请号：US13406508
申请日：2012-02-27
申请人： Richard Koepsel , Gabriel Amitai , Alan J. Russell , Hironobu Murata
发明人： Richard Koepsel , Gabriel Amitai , Alan J. Russell , Hironobu Murata
IPC分类号： A62D3/30 , A01P1/00 , C08F220/56 , A01N37/46
CPC分类号： C08F220/54 , A01N33/12 , A01N33/24 , A01N63/02 , A62D3/02 , A62D2101/02 , A62D2101/04 , D01D5/0007 , D01F1/103 , D01F6/70 , C08F220/52 , A01N25/34 , A01N59/00 , A01N59/08 , A01N59/12
摘要： A system includes at least one oxidase. at least one haloperoxidase; at least a first polymer including groups exhibiting nucleophilic activity for organophosphorus compounds, and a source of halide ions to serve as a substrate for haloperoxidase-catalyzed generation of halogens. The source of halide ions may, for example, include salt crystals or a salt in an extended release system. In a number of embodiments, the first polymer includes halide ions.
摘要翻译：系统包括至少一种氧化酶。至少一种卤代过氧化物酶; 至少包括对有机磷化合物显示亲核活性的基团的第一聚合物，以及用作卤代过氧化物酶催化产生卤素的底物的卤离子源。卤离子源可以例如在延长释放系统中包括盐晶体或盐。在许多实施方案中，第一聚合物包括卤离子。

3. 发明授权

US07139229B2 Optical disk identification circuit 有权
标题翻译：光盘识别电路
公开(公告)号：US07139229B2
公开(公告)日：2006-11-21
申请号：US10085742
申请日：2002-02-26
申请人： Koyu Yamanoi , Toshio Yamauchi , Hironobu Murata
发明人： Koyu Yamanoi , Toshio Yamauchi , Hironobu Murata
IPC分类号： G11B7/00
CPC分类号： G11B7/08511 , G11B2007/0006
摘要： The present invention offers an optical disk determination circuit that can improve the stability of the operation to detect the peak (pulse signal) of the received light signal, and that can improve the stability of the optical disk determination operation. When determining the type of optical disk corresponding to the depth from the surface of the plane on which a light beam is irradiated to the data recording layer, light is irradiated while varying the focal position of the light beam at a constant velocity in one direction of the depth direction from the surface of the optical disk. The bottom level of the received light signal corresponding to the intensity of this reflected light is clamped at a specified level by the bottom clamp circuit 43. The received light signal with the bottom level clamped is compared with a specified reference voltage Vref by the comparator 45, and the received light signal peak (pulse signal) is detected corresponding to the results of this comparison. The type of optical disk is determined by measuring the difference in this peak (pulse signal) detection time.
摘要翻译：本发明提供一种光盘确定电路，其可以提高检测接收光信号的峰值（脉冲信号）的操作的稳定性，并且可以提高光盘确定操作的稳定性。当确定与从其上照射有光束的平面的表面相对应的光盘类型到数据记录层时，照射光，同时以恒定速度在一个方向上改变光束的焦点位置从光盘表面的深度方向。对应于该反射光的强度的接收光信号的底部电平被底部钳位电路43钳位在指定电平。通过比较器45将接收到的底电平的接收光信号与指定的参考电压Vref进行比较，并且根据该比较的结果检测接收到的光信号峰值（脉冲信号）。通过测量该峰值（脉冲信号）检测时间的差异来确定光盘的类型。

4. 发明授权

US07126889B2 Tracking error detector 有权
标题翻译：跟踪误差检测器
公开(公告)号：US07126889B2
公开(公告)日：2006-10-24
申请号：US10314821
申请日：2002-12-09
申请人： Koyu Yamanoi , Hironobu Murata , Aoe Takashi
发明人： Koyu Yamanoi , Hironobu Murata , Aoe Takashi
IPC分类号： G11B7/00
CPC分类号： G11B7/131 , G11B7/0901 , G11B7/0903 , G11B7/0943
摘要： A circuit to improve the SN characteristic of a tracking error signal. This tracking error detection circuit is formed as a push-pull system utilizing a quadrant type photo-detector and provided with 4 gain control amplifiers 20, 22, 24, and 26, 4 bottom envelope circuits 28, 30, 32, and 34, a pair of subtracting circuits 36 and 38, adding (subtracting) circuit 40, offset circuit 42, and gain control circuit 44. Bottom envelope circuits 28, 30, 32, and 34 are configured with a capacitor-type peak-hold circuit, for example, whereby bottom envelopes of RF signals SA, SB, SC, and SD given from light receiving areas A, B, C, and D of a photo-detector via gain control amplifiers 20, 22, 24, and 26 are detected, and bottom envelope signals SAbtm, SBbtm, SCbtm, and SDbtm representing the waveforms of the respective bottom envelopes are output.
摘要翻译：一种提高跟踪误差信号的SN特性的电路。该跟踪误差检测电路形成为利用象限型光检测器并具有4个增益控制放大器20,22,24和26,4个底包络电路28,30,32和34的推挽系统，一对减法电路36和38，添加（减）电路40，偏移电路42和增益控制电路44.底包络电路28,30,32和34由电容器型峰保持电路构成，例如，由此检测通过增益控制放大器20,22,24和26从光电检测器的光接收区域A，B，C和D给出的RF信号SA，SB，SC和SD的底部信封，并且底部输出表示相应底部信封的波形的包络信号SAbtm，SBbtm，SCbtm和SDbtm。

5. 发明授权

US06535033B2 Peak hold circuit 有权
标题翻译：峰值保持电路
公开(公告)号：US06535033B2
公开(公告)日：2003-03-18
申请号：US09733180
申请日：2000-12-07
申请人： Toshio Yamauchi , Hironobu Murata , Osamu Hosokawa
发明人： Toshio Yamauchi , Hironobu Murata , Osamu Hosokawa
IPC分类号： G11C2702
CPC分类号： H03K5/1532
摘要： A peak detector for detecting a peak signal includes an input circuit for inputting an input signal, a differential comparator for comparing the input signal with the peak signal to generate a difference signal, a diverting circuit to divert current between a first current path and a second current path based on the difference signal, and a comparator to accept current from the first current path and not from the second current path and to form the peak signal resulting from the current.
摘要翻译：用于检测峰值信号的峰值检测器包括用于输入输入信号的输入电路，用于将输入信号与峰值信号进行比较以产生差分信号的差分比较器，用于在第一电流路径和第二电流路径之间转移电流的转向电路基于差分信号的电流路径，以及比较器，用于从第一电流路径接收电流而不从第二电流路径接收电流，并形成由电流产生的峰值信号。

6. 发明授权

US08638381B2 Backside illumination image sensor, manufacturing method thereof and image-capturing device 有权
标题翻译：背面照明图像传感器，其制造方法和图像捕获装置
公开(公告)号：US08638381B2
公开(公告)日：2014-01-28
申请号：US12702456
申请日：2010-02-09
申请人： Hironobu Murata
发明人： Hironobu Murata
IPC分类号： H04N5/335
CPC分类号： H04N5/3745 , G02B3/0056 , G02B5/201 , H01L27/14621 , H01L27/14623 , H01L27/14627 , H01L27/14636 , H01L27/1464 , H04N5/23212 , H04N5/3696 , H04N5/3741
摘要： A backside illumination image sensor equipped with a plurality of pixels disposed in a two-dimensional pattern, includes: image-capturing pixels; and focus detection pixels.
摘要翻译：配备有以二维图案配置的多个像素的背面照明图像传感器包括：图像拍摄像素; 和焦点检测像素。

7. 发明授权

US08379121B2 Image-capturing device and imaging apparatus 有权
标题翻译：图像捕获装置和成像装置
公开(公告)号：US08379121B2
公开(公告)日：2013-02-19
申请号：US13083093
申请日：2011-04-08
申请人： Hironobu Murata
发明人： Hironobu Murata
IPC分类号： H04N5/232 , H04N9/083 , H04N9/04 , H04N3/14 , H04N5/335 , G03B27/10
CPC分类号： H04N5/23212 , G02B7/36 , G03B3/10 , G03B13/18 , G03B13/36 , H04N5/3696 , H04N9/09
摘要： An image-capturing device includes: a first image sensor equipped with first and second image-capturing pixels and first focus detection pixels, each of which receives one of light fluxes formed by splitting subject light having passed through an optical system, the first and the second image-capturing pixels generating first and second color signals respectively and the first focus detection pixels outputting focus detection signals indicating a state of focus detection pertaining to the optical system; and a second image sensor equipped with third image-capturing pixels and second focus detection pixels, each of which receives another light flux, the third image-capturing pixels generating third color signals and the second focus detection pixels outputting focus detection signals, wherein: when n represents a quantity of the first image-capturing pixels, quantities of the second and the third image-capturing pixels, and the first and the second focus detection pixels are n, 2n, 2n and 2n respectively.
摘要翻译：图像捕获装置包括：配备有第一和第二图像捕获像素的第一图像传感器和第一焦点检测像素，每个第一焦点检测像素接收通过分割通过光学系统的被摄体光形成的光束之一，第一和第第二图像捕获像素分别产生第一和第二颜色信号，并且第一焦点检测像素输出指示与光学系统有关的焦点检测状态的焦点检测信号; 以及配备有第三图像拍摄像素和第二焦点检测像素的第二图像传感器，每个第三图像捕获像素和第二焦点检测像素接收另一个光束，所述第三图像捕获像素产生第三颜色信号，并且所述第二焦点检测像素输出焦点检测信号，其中： n表示第一图像拍摄像素的数量，第二和第三图像拍摄像素的量，第一和第二焦点检测像素分别为n，2n，2n和2n。

8. 发明授权

US07158455B2 Servo error detecting device for optical disk 有权
标题翻译：光盘伺服错误检测装置
公开(公告)号：US07158455B2
公开(公告)日：2007-01-02
申请号：US10339376
申请日：2003-01-09
申请人： Hironobu Murata , Takashi Aoe , Koyu Yamanoi
发明人： Hironobu Murata , Takashi Aoe , Koyu Yamanoi
IPC分类号： G11B7/004
CPC分类号： G11B7/094 , G11B7/08511
摘要： Servo error signal circuitry apparatus and methods are described. The difference between two bottom envelope signals SEbtm and SFbtm is calculated by a subtracter (40) to generate a difference signal (SEbtm−SFbtm). The difference signal (SEbtm−SFbtm) is input as an alignment signal (AL) to an equalizer (42) and as a basic tracking error signal to the positive input terminal of a second subtracter (52). On the other hand, the difference between two top envelope signals SEtop and SFtop is calculated by a third subtracter (48) to generate a difference signal (SEtop−SFtop). The signal K(SEtop−SFtop) obtained by multiplying a coefficient K with the difference signal using a coefficient multiplier (50) is input to the negative input terminal of the second subtracter (52). The difference signal {(SEbtm−SFbtm)−K(SEtop−SFtop)} output from the second subtracter (52) is used as an offset corrected tracking error signal.
摘要翻译：描述了伺服误差信号电路装置和方法。通过减法器（40）计算两个底包络信号SEbtm和SFbtm之间的差异，以产生差分信号（SEbtm-SFbtm）。将差分信号（SEbtm-SFbtm）作为对准信号（AL）输入到均衡器（42），并作为基本跟踪误差信号输入到第二减法器（52）的正输入端。另一方面，通过第三减法器（48）计算两个顶包络信号SEtop和SFtop之间的差异，以产生差分信号（SEtop-SFtop）。通过使用系数乘法器（50）将系数K与差分信号相乘而获得的信号K（SEtop-SFtop）被输入到第二减法器（52）的负输入端子。从第二减法器（52）输出的差分信号{（SEbtm-SFbtm）-K（SEtop-SFtop）}用作偏移校正跟踪误差信号。

9. 发明授权

US09539338B2 Polymer-based protein engineering methods to rationally tune enzyme activity, pH-dependence and stability 有权
标题翻译：基于聚合物的蛋白质工程方法合理调节酶活性，pH依赖性和稳定性
公开(公告)号：US09539338B2
公开(公告)日：2017-01-10
申请号：US14785868
申请日：2014-04-22
申请人： Alan J. Russell , Richard R. Koepsel , Chad Cummings , Hironobu Murata
发明人： Alan J. Russell , Richard R. Koepsel , Chad Cummings , Hironobu Murata
IPC分类号： A61K47/48 , C08F289/00 , C08H1/00 , A61K38/48
CPC分类号： A61K47/48176 , A61K38/4826 , A61K47/48769 , A61K47/58 , A61K47/69 , C08F289/00 , C08H1/00 , C12Y304/21001
摘要： Using a novel water-soluble, active ester amide-containing functionalized controlled radical polymerization initiator, stimuli responsive polymers have been grown from the surface of a protein, exemplified by chymotrypsin or any protein having surface amino acids that will covalently bind to the active ester amide-containing functionalized initiator. It is shown that changes in temperature or pH can change the conformation of the polymer surrounding the enzyme, which in turn enabled the rational tailoring of enzyme activity and stability. This method has afforded an increase in the activity and stability of the enzyme by an order of magnitude at pH's where the enzyme is usually inactive or unstable. Multimodal temperature responsive protein-block copolymer conjugates are described.
摘要翻译：使用新的具有水溶性的含活性酯酰胺的官能化受控自由基聚合引发剂，已经从蛋白质的表面生长了刺激响应性聚合物，例如糜蛋白酶或具有共价结合活性酯酰胺的表面氨基酸的任何蛋白质的官能化引发剂。显示温度或pH的变化可以改变酶周围的聚合物的构象，这反过来使得酶活性和稳定性的合理调整。这种方法使酶的活性和稳定性提高了一个数量级的pH值，其中酶通常是无活性的或不稳定的。描述了多峰温度反应性蛋白质 - 嵌段共聚物缀合物。

10. 发明申请

US20160101190A1 POLYMER-BASED PROTEIN ENGINEERING METHODS TO RATIONALLY TUNE ENZYME ACTIVITY, pH-DEPENDENCE AND STABILITY 有权
标题翻译：基于聚合物的蛋白质工程方法来显着调节酶活性，pH依赖性和稳定性
公开(公告)号：US20160101190A1
公开(公告)日：2016-04-14
申请号：US14785868
申请日：2014-04-22
申请人： Alan J. Russell , Richard R. Koepsel , Chad Cummings , Hironobu Murata
发明人： Alan J. Russell , Richard R. Koepsel , Chad Cummings , Hironobu Murata
IPC分类号： A61K47/48 , A61K38/48
CPC分类号： A61K47/48176 , A61K38/4826 , A61K47/48769 , A61K47/58 , A61K47/69 , C08F289/00 , C08H1/00 , C12Y304/21001
摘要： Using a novel water-soluble, active ester amide-containing functionalized controlled radical polymerization initiator, stimuli responsive polymers have been grown from the surface of a protein, exemplified by chymotrypsin or any protein having surface amino acids that will covalently bind to the active ester amide-containing functionalized initiator. It is shown that changes in temperature or pH can change the conformation of the polymer surrounding the enzyme, which in turn enabled the rational tailoring of enzyme activity and stability. This method has afforded an increase in the activity and stability of the enzyme by an order of magnitude at pH's where the enzyme is usually inactive or unstable. Multimodal temperature responsive protein-block copolymer conjugates are described.
摘要翻译：使用新的具有水溶性的含活性酯酰胺的官能化受控自由基聚合引发剂，已经从蛋白质的表面生长了刺激响应性聚合物，例如糜蛋白酶或具有共价结合活性酯酰胺的表面氨基酸的任何蛋白质的官能化引发剂。显示温度或pH的变化可以改变酶周围的聚合物的构象，这反过来使得酶活性和稳定性的合理调整。这种方法使酶的活性和稳定性提高了一个数量级的pH值，其中酶通常是无活性的或不稳定的。描述了多峰温度反应性蛋白质 - 嵌段共聚物缀合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式