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    • 3. 发明申请
    • VACUUM PROCESSING APPARATUS AND VACUUM PROCESSING METHOD
    • 真空加工设备和真空加工方法
    • US20120156887A1
    • 2012-06-21
    • US13392010
    • 2010-08-24
    • Youhei OnoMasaaki KawanaYutaka Miura
    • Youhei OnoMasaaki KawanaYutaka Miura
    • H01L21/306H01L21/3065
    • H01J37/32422H01J37/32357H01J37/3244H01J37/32449H01L21/02046H01L21/02063H01L21/76814
    • A vacuum processing apparatus, comprising: a processing chamber 3 in which an object to be processed is placed and a predetermined vacuum state is formed; a first processing gas introducing means 12 for converting a first processing gas into a radical state and introducing the resulting first processing gas in the radical state into the processing chamber through first processing gas introducing ports which open to the interior of the processing chamber; a second processing gas introducing means 15 for introducing a second processing gas, which is reactive with the first processing gas in the radical state, into the processing chamber through second processing gas introducing ports which open to the interior of the processing chamber; a temperature controlling means for controlling the temperature within the processing chamber 3 to a first temperature-controlled state, in which the first processing gas in the radical state and the second processing gas process the surface of the object to be processed, thereby producing a reaction product, and to a second temperature-controlled state in which the resulting reaction product is sublimated and removed; and an inert gas introducing means for introducing an inert gas into the processing chamber 3 through the processing gas introducing ports 12 when the temperature controlling means controls the temperature within the processing chamber to the second temperature-controlled state.
    • 一种真空处理装置,包括:处理室3,其中放置有待加工物体并形成预定的真空状态; 第一处理气体引入装置12,用于将第一处理气体转化为自由基状态,并将所得到的自由基状态的第一处理气体通过向处理室的内部开放的第一处理气体导入口引入处理室; 第二处理气体引入装置15,用于将通过自由基状态的第一处理气体反应的第二处理气体通过向处理室内部开放的第二处理气体导入口引入处理室; 温度控制装置,用于将处理室3内的温度控制到第一温度控制状态,其中自由基状态的第一处理气体和第二处理气体处理待处理物体的表面,从而产生反应 产物和第二温度控制状态,其中所得反应产物升华和除去; 以及惰性气体引入装置,当温度控制装置将处理室内的温度控制到第二温度控制状态时,通过处理气体导入口12将惰性气体引入处理室3。
    • 7. 发明申请
    • Method of Judging Grade of Malignancy of Carcinoma Cell
    • 判断癌细胞恶性程度的方法
    • US20090004647A1
    • 2009-01-01
    • US11658784
    • 2005-07-29
    • Yutaka MiuraMakoto KawaguchiHirotaka IwaseMinoru HamazakiJung Cha-GyunHitoo Nishino
    • Yutaka MiuraMakoto KawaguchiHirotaka IwaseMinoru HamazakiJung Cha-GyunHitoo Nishino
    • C12Q1/68C12Q1/02C07K16/18
    • G01N33/57496C07K16/30C12Q1/6883C12Q1/6886C12Q2600/106C12Q2600/112C12Q2600/118
    • Means for easily determining the grade of malignancy of cancer cells. The amount of ATBF1 in the whole cell structure of test cancer cells separated from a living organism is detected, and on the basis of detection results, the grade of malignancy of test cancer cells is judged. Alternatively, the amount of ATBF1 in the nuclei of test cancer cells separated from a living organism is detected, and on the basis of detection results, the grade of malignancy of test cancer cells is judged. Still alternatively, the amount of ATBF1 in the cytoplasms of test cancer cells separated from a living organism is detected, and on the basis of detection results, the grade of malignancy of test cancer cells is judged. In a preferred from, at least one of (1) the amount of intranuclear presence and/or intracytoplasmic presence a region corresponding to exon 10 of an ATBF1 gene, (2) the amount of intranuclear presence and/or intracytoplasmic presence a region corresponding to exon 11 of an ATBF1 gene, and (3) the amount of intranuclear presence and/or intracytoplasmic presence a region corresponding to exon 3 of an ATBF1 gene is detected as the amount of ATBF1.
    • 用于容易确定癌细胞恶性程度的方法。 检测从生物体分离出的检测癌细胞的全细胞结构中的ATBF1的量,根据检测结果判断检测癌细胞的恶性程度。 或者,检测从活体分离的检测癌细胞的细胞核中的ATBF1的量,根据检测结果判断检测癌细胞的恶性程度。 或者,检测从活体分离的检测癌细胞的细胞质中的ATBF1的量,根据检测结果判断检测癌细胞的恶性程度。 优选地,(1)与ATBF1基因的外显子10相对应的区域的核内存在量和/或胞质内存在的量中的至少一种,(2)核内存在量和/或胞质内存在的量对应于 ATBF1基因的外显子11,(3)ATBF1基因的外显子3相应的区域的核内存在和/或胞质内存在量被检测为ATBF1的量。
    • 10. 发明授权
    • Method of judging grade of malignancy of carcinoma cell using ATBF-1
    • 使用ATBF-1判断癌细胞恶性程度的方法
    • US07871788B2
    • 2011-01-18
    • US11658784
    • 2005-07-29
    • Yutaka MiuraMakoto KawaguchiHirotaka IwaseMinoru HamazakiJung Cha-GyunHitoo Nishino
    • Yutaka MiuraMakoto KawaguchiHirotaka IwaseMinoru HamazakiJung Cha-GyunHitoo Nishino
    • G01N33/574G01N33/53
    • G01N33/57496C07K16/30C12Q1/6883C12Q1/6886C12Q2600/106C12Q2600/112C12Q2600/118
    • Means for easily determining the grade of malignancy of cancer cells. The amount of ATBF1 in the whole cell structure of test cancer cells separated from a living organism is detected, and on the basis of detection results, the grade of malignancy of test cancer cells is judged. Alternatively, the amount of ATBF1 in the nuclei of test cancer cells separated from a living organism is detected, and on the basis of detection results, the grade of malignancy of test cancer cells is judged. Still alternatively, the amount of ATBF1 in the cytoplasms of test cancer cells separated from a living organism is detected, and on the basis of detection results, the grade of malignancy of test cancer cells is judged. In a preferred from, at least one of (1) the amount of intranuclear presence and/or intracytoplasmic presence a region corresponding to exon 10 of an ATBF1 gene, (2) the amount of intranuclear presence and/or intracytoplasmic presence a region corresponding to exon 11 of an ATBF1 gene, and (3) the amount of intranuclear presence and/or intracytoplasmic presence a region corresponding to exon 3 of an ATBF1 gene is detected as the amount of ATBF1.
    • 用于容易确定癌细胞恶性程度的方法。 检测从生物体分离出的检测癌细胞的全细胞结构中的ATBF1的量,根据检测结果判断检测癌细胞的恶性程度。 或者,检测从活体分离的检测癌细胞的细胞核中的ATBF1的量,根据检测结果判断检测癌细胞的恶性程度。 或者,检测从活体分离的检测癌细胞的细胞质中的ATBF1的量,根据检测结果判断检测癌细胞的恶性程度。 优选地,(1)与ATBF1基因的外显子10相对应的区域的核内存在量和/或胞质内存在的量中的至少一种,(2)核内存在量和/或胞质内存在的量对应于 ATBF1基因的外显子11,(3)ATBF1基因的外显子3相应的区域的核内存在和/或胞质内存在量被检测为ATBF1的量。