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1. 发明专利

JP2010269158A Intestinal sleeve 有权
标题翻译： INTESTINAL SLEEVE
公开(公告)号：JP2010269158A
公开(公告)日：2010-12-02
申请号：JP2010161693
申请日：2010-07-16
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVID A , MEADE JOHN C
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/04 , A61F5/00 , A61L27/00 , A61L29/00 , A61L31/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： PROBLEM TO BE SOLVED: To provide a method and apparatus for limiting absorption of food products in specific parts of the digestive system. SOLUTION: A gastrointestinal implant device is anchored in the duodenum and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor (2810) for attaching the device to the duodenum, and an unsupported flexible sleeve (202) for limiting absorption of nutrients in the duodenum. The anchor coupled to an upstream portion of the sleeve whose downstream end is unsupported, and locked to a duodenal wall and having a completely relaxed diameter of at least 40 millimeters, can include a stent and/or a wave anchor and is collapsible for catheter-based delivery and removal. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种限制消化系统特定部位食品吸收的方法和装置。解决方案：胃肠道植入器械固定于十二指肠，并延伸超过Treitz的韧带。所有离开胃的食物都通过设备进行漏斗。胃肠装置包括用于将装置附接到十二指肠的锚固件（2810）和用于限制十二指肠中营养物吸收的无支撑柔性套管（202）。锚固件联接到套筒的上游部分，其下游端未被支撑，并且锁定到十二指肠壁并具有至少40毫米的完全松弛的直径，可以包括支架和/或波浪锚，并且可折叠用于导管 - 基于交付和移除。版权所有（C）2011，JPO＆INPIT

2. 发明专利

JP2013090940A Gastrointestinal implant delivery system and delivery assembly with gastrointestinal implant device 有权
标题翻译：胃肠道输送系统和输送装置与胃肠道植入装置
公开(公告)号：JP2013090940A
公开(公告)日：2013-05-16
申请号：JP2013004251
申请日：2013-01-15
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVID A , MEADE JOHN C
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： PROBLEM TO BE SOLVED: To provide a delivery system and a delivery assembly delivering a device for limiting absorption of food products in specific parts of the digestive system.SOLUTION: The delivery system 2600 delivers the gastrointestinal implant device 200 gastrointestinally. The gastrointestinal implant device 200 is provided with: an anchor 208 which is anchored in the duodenum, extends beyond the ligament of Treitz, and anchors the device in the duodenum; and an unsupported flexible sleeve 202 for limiting absorption of nutrient in the duodenum. The delivery system 2600 an outer sheath 1202 for storing an upstream part of the gastrointestinal implant device 200, an inner sheath 1226 positioned inside the outer sheath and extending toward a downstream end of the delivery system 2600 beyond the outer sheath, a release mechanism for releasing the anchor 208 from the outer sheath 1202, and a sleeve release mechanism 1224 for releasing the downstream end of the sleeve 202.
摘要翻译：要解决的问题：提供递送系统和递送组件，其递送用于限制消化系统的特定部分中的食品吸收的装置。解决方案：输送系统2600胃肠道输注装置200胃肠输送。胃肠道植入装置200设置有：锚固在十二指肠中的锚固件208延伸超过Treitz的韧带，并将该装置固定在十二指肠中; 以及用于限制十二指肠中营养素的吸收的无支撑的柔性套筒202。输送系统2600包括用于存储胃肠植入装置200的上游部分的外护套1202，位于外护套内部并且朝向输送系统2600的下游端延伸超过外护套的内护套1226，用于释放的释放机构来自外护套1202的锚定件208和用于释放套筒202的下游端的套筒释放机构1224.（C）2013，JPO和INPIT

3. 发明专利

JP2011251164A Method and device for placing gastrointestinal sleeve 有权
标题翻译：用于放置胃肠管的方法和装置
公开(公告)号：JP2011251164A
公开(公告)日：2011-12-15
申请号：JP2011179166
申请日：2011-08-18
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , MELANSON DAVID A , LAMPORT RONALD B
IPC分类号： A61B17/00 , A61F2/04 , A61F5/00 , A61M25/01
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/9517
摘要： PROBLEM TO BE SOLVED: To provide a method and a device for delivering or placing gastrointestinal implant device into a mammal.SOLUTION: The gastrointestinal implant device can be used to limit absorption of food products in specific parts of the digestive system and can include a gastrointestinal sleeve having an anchor portion and a barrier or sleeve portion. The method includes the endoscopic delivery of the device.
摘要翻译：要解决的问题：提供一种用于将胃肠道植入装置递送或放置到哺乳动物中的方法和装置。解决方案：消化道植入装置可以用于限制消化系统的特定部分中的食品的吸收，并且可以包括具有锚定部分和屏障或套筒部分的胃肠套筒。该方法包括装置的内窥镜输送。版权所有（C）2012，JPO＆INPIT

4. 发明申请

WO2006133311A3 GASTROINTESTINAL ANCHOR COMPLIANCE 审中-公开
标题翻译：气管内固定器符合性
公开(公告)号：WO2006133311A3
公开(公告)日：2007-03-15
申请号：PCT/US2006022168
申请日：2006-06-07
申请人： GI DYNAMICS INC , LEVINE ANDY H , MELANSON DAVID A
发明人： LEVINE ANDY H , MELANSON DAVID A
IPC分类号： A61F5/00 , A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F2002/044
摘要： A collapsible gastrointestinal anchor can be characterized in various embodiments by a radial force of about 0.1 Newtons (N) or greater at a compressed diameter of 25 millimeters (mm); by an average spring rate of about 13 Newtons/meter (N/m) or greater in a range of motion between a relaxed diameter and a compressive elastic deformation diameter; or by a radial force over the range of motion of about 0.1 N or greater. Typically, the anchor can be adapted to be retained within a subject's intestine, more typically in the duodenum, or particularly in the duodenal bulb just distal to the pylorus. A gastrointestinal implant device includes the collapsible gastrointestinal anchor and a floppy sleeve. The sleeve is open at both ends and adapted to extend into a subject's intestine, the anchor being coupled to a proximal portion of the sleeve. Also include are methods of implanting the gastrointestinal implant device in a subject, and methods of treating a subject for disease. The disclosed gastrointestinal invention leads to an improved ability to secure anchors and devices in the gastrointestinal tract while tending to minimize migration.
摘要翻译：可折叠的胃肠锚固体可以在各种实施方案中通过在25毫米（mm）的压缩直径下的约0.1牛顿（N）或更大的径向力来表征; 在松弛直径和压缩弹性变形直径之间的运动范围内的平均弹簧速率为约13牛顿/米（N / m）或更大; 或通过约0.1N或更大的运动范围内的径向力。通常，锚可适于保持在受试者的肠内，更典型地保留在十二指肠内，特别是在幽门远端的十二指肠球囊中。消化道植入装置包括可折叠的胃肠锚和软管。套筒在两端是敞开的，并且适于延伸到被检者的肠内，锚固件联接到套筒的近端部分。还包括在受试者中植入胃肠道植入装置的方法以及治疗受试者疾病的方法。所公开的胃肠道发明导致改善在胃肠道中固定锚和装置的能力，同时倾向于使迁移最小化。

5. 发明专利

AU2006227471B8 Positioning/repositioning device 未知
公开(公告)号：AU2006227471B8
公开(公告)日：2010-07-22
申请号：AU2006227471
申请日：2006-03-17
申请人： GI DYNAMICS INC
发明人： MELANSON DAVID A , LAMPORT RONALD B
IPC分类号： A61B17/22 , A61B17/00 , A61B17/34
摘要： A device for repositioning an implantable device within a natural bodily lumen includes an inner tube defining an internal lumen and adapted for insertion into a natural bodily lumen. An elongated member is slidably or rotatably disposed within the lumen of the inner tube, with a grasper disposed at the distal end of the elongated member adapted to grasp a portion of the implantable device. The implantable device, once grasped, can be at least partially collapsed. For example, a hook-shaped grasper grasps a drawstring of the implantable device, manipulating the drawstring and causing the implant to radially collapse. A retrieval hood is advanced over the collapsed portion of the implantable device. While maintaining its grasp, the repositioning device and the implantable device can then be repositioned or removed as one unit from the body by pulling the repositioning device from its proximal end.

6. 发明专利

CA2601620A1 REMOVAL AND REPOSITIONING DEVICE 未知
公开(公告)号：CA2601620A1
公开(公告)日：2006-09-28
申请号：CA2601620
申请日：2006-03-17
申请人： GI DYNAMICS INC
发明人： LAMPORT RONALD B , MELANSON DAVID A
IPC分类号： A61B17/22 , A61B17/00 , A61B17/34
摘要： A device for repositioning an implantable device within a natural bodily lumen includes an inner tube defining an internal lumen and adapted for insertion into a natural bodily lumen. An elongated member is slidably or rotatably disposed within the lumen of the inner tube, with a grasper disposed at the distal end of the elongated member adapted to grasp a portion of the implantable device. The implantable device, once grasped, can be at least partially collapsed. For example, a hook-shaped grasper grasps a drawstring of the implantable device, manipulating the drawstring and causing the implant to radially collapse. A retrieval hood is advanced over the collapsed portion of the implantable device. While maintaining its grasp, the repositioning device and the implantable device can then be repositioned or removed as one unit from the body by pulling the repositioning device from its proximal end.

7. 发明专利

AU2004305450A1 Intestinal sleeve 未知
公开(公告)号：AU2004305450A1
公开(公告)日：2005-07-07
申请号：AU2004305450
申请日：2004-06-01
申请人： GI DYNAMICS INC
发明人： MEADE JOHN C , LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVID A
IPC分类号： A61F5/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/04

8. 发明专利

AU2010292118B9 Anchors with open heads 未知
公开(公告)号：AU2010292118B9
公开(公告)日：2014-01-09
申请号：AU2010292118
申请日：2010-09-10
申请人： GI DYNAMICS INC
发明人： SHANK PETER , MELANSON DAVID A , MAXWELL BARRY , HOLMES SEAN K , LOPER JAMES , PARKER IAN K , LEVINE ANDY H
IPC分类号： A61F2/04 , A61B17/064 , A61F2/02 , A61F2/82 , A61F5/00
摘要： An implant (100) includes a protrusion (110) with an open or rounded loop (112) (or open head) connected to a collapsible anchor. The protrusion may include a straight length of wire (114) or a helical length wire, with one or more wire loops (112) at the end of the length forming the loop. Upon deployment within the gastrointestinal tract, the protrusion expands from a collapsed state, alongside the anchor, to a relaxed state, in which the protrusion extends outward from the anchor. As the protrusion expands to its relaxed state, it pushes the loop into the wall of the duodenum, causing the loop to penetrate the duodenal wall. A pocket of scar tissue forms about the head and possibly through an opening in the head, securing the anchor within the duodenum. The implant may also include a thin-walled sleeve that is coupled to the anchor and extended from the anchor into the intestine.

9. 发明专利

DE112011102287T5 Befestigungen mit bioabbaubaren Verformungsbehinderungen 未知
公开(公告)号：DE112011102287T5
公开(公告)日：2013-05-02
申请号：DE112011102287
申请日：2011-06-29
申请人： GI DYNAMICS INC
发明人： NUTTING CHRISTOPHER , PANEK JOHN , MAXWELL BARRY , SHANK PETER , MELANSON DAVID A
IPC分类号： A61F2/04 , A61B17/064 , A61F2/00 , A61F2/02 , A61F2/82 , A61F5/00
摘要： Ein Implantat (100) weist eine zusammenklappbare Befestigung (102) auf, die in ein Lumen eingesetzt werden soll, und einen Vorsprung (102), der mit der Befestigung verbunden ist. Der Vorsprung erstreckt sich in einem eingezwängten Zustand in einem Abstand von einer äußeren Oberfläche der Befestigung aus, und in einem nicht-eingezwängten Zustand sich weiter von der äußeren Oberfläche der Befestigung. Eingeschlossen ist auch eine bioabbaubare Verformungsbehinderung, beispielsweise eine Röhre oder eine chirurgische Naht, die so ausgebildet ist, dass sie den Vorsprung im eingezwängten Zustand hält, bis sich die Verformungsbehinderung löst. Das Implantat kann zusätzliche bioabbaubare Verformungsbehinderungen (244) aufweisen, wobei jede Verformungsbehinderung so ausgestaltet ist, dass sie den Vorsprung in einem unterschiedlichen eingezwängten Zustand hält und über eine unterschiedliche festgelegte Zeitdauer abbaut, nachdem das Implantat in das Lumen eingesetzt worden ist. Der Vorsprung kann einen beidseitigen Widerhaken oder eine offene Schlinge aufweisen. Der Vorsprung kann so ausgestaltet sein, dass er eine Wandung des Lumens penetriert und es ermöglicht, dass Gewebe um den Vorsprung herum wächst. Das Implantat kann auch eine nicht-unterstützte, dünnwandige Manschette aufweisen, die an die Befestigung gekoppelt und so ausgestaltet ist, dass sie sich beim Einsetzen der zusammenklappbaren Befestigung in das Lumen erstreckt.

10. 发明专利

HK1168022A1 ANCHORS WITH OPEN HEADS 未知
公开(公告)号：HK1168022A1
公开(公告)日：2012-12-21
申请号：HK12109016
申请日：2012-09-13
申请人： GI DYNAMICS INC
发明人： SHANK PETER , MELANSON DAVID A , MAXWELL BARRY , HOLMES SEAN K , LOPER JAMES , PARKER IAN K , LEVINE ANDY H
IPC分类号： A61B20060101 , A61F2/04

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