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1. 发明专利

JP2010104853A Obesity therapeutic sleeve 有权
标题翻译： BARIATRIC SLEEVE
公开(公告)号：JP2010104853A
公开(公告)日：2010-05-13
申请号：JP2010033475
申请日：2010-02-18
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
IPC分类号： A61B17/04 , A61B17/06 , A61F2/00 , A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/00867 , A61B2017/0419 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039
摘要： PROBLEM TO BE SOLVED: To provide a method and apparatus for the application of an obstruction sleeve within the gastrointestinal tract to limit absorption of food products in a specific parts of the gastrointestinal tract and to provide negative feedback to a patient who are morbidly obese to enable the patient to improve eating habits. SOLUTION: A gastrointestinal implant device includes a flexible sleeve which is open at both ends, and adapted to extend into the intestine to limit the absorption of nutrients in the intestine, and a stent formed from a network of struts, coupled to a proximal portion of the sleeve, and adapted to fasten the sleeve. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种在胃肠道内应用阻塞套筒的方法和装置，以限制食物在胃肠道的特定部位的吸收，并向患病病人提供负反馈肥胖使患者能够改善饮食习惯。解决方案：胃肠道植入装置包括柔性套筒，其在两端是开放的，并且适于延伸到肠中以限制肠中的营养物质的吸收，以及由支柱网络形成的支架，套筒的近端部分，并且适于紧固套筒。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2014004467A Obesity treatment sleeve 审中-公开
标题翻译：肥胖治疗套
公开(公告)号：JP2014004467A
公开(公告)日：2014-01-16
申请号：JP2013178574
申请日：2013-08-29
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61F2/00 , A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/00867 , A61B2017/0419 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039
摘要： PROBLEM TO BE SOLVED: To provide a device for implanting an inhibition sleeve inside the gastrointestinal tract in order to restrict food absorption in certain regions of the gastrointestinal tract and provide negative feedback which enables morbid obesity patients to improve their dietary habits.SOLUTION: The gastrointestinal tract implanted device in the present invention includes: a flexible sleeve 202 not supported at the distal end, opening at both ends, extending into the intestines, which restricts absorption of nutrients in the intestines, impregnated with chemicals, and made of thin and flexible material so as to be capable of contracting to a small volume in the inside of the intestines; and a self-expanding and contractible anchor 208 connected to the proximal end of the sleeve 202, anchoring the proximal end of the sleeve 202 to the inside of the gastrointestinal tract.
摘要翻译：要解决的问题：提供一种用于在胃肠道内植入抑制套筒的装置，以限制在胃肠道的某些区域中的食物吸收，并提供负面反馈，使得病态肥胖患者能够改善其饮食习惯。解决方案：胃肠道本发明的植入植入装置包括：柔性套筒202，其不支撑在远端，在两端开口延伸到肠中，限制肠中营养物的吸收，浸渍有化学物质，并由薄而柔软的材料制成以便能够在肠内收缩至少量; 以及连接到套筒202的近端的自膨胀和收缩的锚固件208，将套筒202的近端固定到胃肠道的内部。

3. 发明专利

JP2010269158A Intestinal sleeve 有权
标题翻译： INTESTINAL SLEEVE
公开(公告)号：JP2010269158A
公开(公告)日：2010-12-02
申请号：JP2010161693
申请日：2010-07-16
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVID A , MEADE JOHN C
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/04 , A61F5/00 , A61L27/00 , A61L29/00 , A61L31/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： PROBLEM TO BE SOLVED: To provide a method and apparatus for limiting absorption of food products in specific parts of the digestive system. SOLUTION: A gastrointestinal implant device is anchored in the duodenum and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor (2810) for attaching the device to the duodenum, and an unsupported flexible sleeve (202) for limiting absorption of nutrients in the duodenum. The anchor coupled to an upstream portion of the sleeve whose downstream end is unsupported, and locked to a duodenal wall and having a completely relaxed diameter of at least 40 millimeters, can include a stent and/or a wave anchor and is collapsible for catheter-based delivery and removal. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种限制消化系统特定部位食品吸收的方法和装置。解决方案：胃肠道植入器械固定于十二指肠，并延伸超过Treitz的韧带。所有离开胃的食物都通过设备进行漏斗。胃肠装置包括用于将装置附接到十二指肠的锚固件（2810）和用于限制十二指肠中营养物吸收的无支撑柔性套管（202）。锚固件联接到套筒的上游部分，其下游端未被支撑，并且锁定到十二指肠壁并具有至少40毫米的完全松弛的直径，可以包括支架和/或波浪锚，并且可折叠用于导管 - 基于交付和移除。版权所有（C）2011，JPO＆INPIT

4. 发明专利

JP2013090940A Gastrointestinal implant delivery system and delivery assembly with gastrointestinal implant device 有权
标题翻译：胃肠道输送系统和输送装置与胃肠道植入装置
公开(公告)号：JP2013090940A
公开(公告)日：2013-05-16
申请号：JP2013004251
申请日：2013-01-15
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVID A , MEADE JOHN C
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0482 , A61B17/12 , A61B2017/0419 , A61B2017/06052 , A61F2/04 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/045 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2002/9511 , A61F2220/0008 , A61F2220/0016 , A61F2220/0058 , A61F2220/0066
摘要： PROBLEM TO BE SOLVED: To provide a delivery system and a delivery assembly delivering a device for limiting absorption of food products in specific parts of the digestive system.SOLUTION: The delivery system 2600 delivers the gastrointestinal implant device 200 gastrointestinally. The gastrointestinal implant device 200 is provided with: an anchor 208 which is anchored in the duodenum, extends beyond the ligament of Treitz, and anchors the device in the duodenum; and an unsupported flexible sleeve 202 for limiting absorption of nutrient in the duodenum. The delivery system 2600 an outer sheath 1202 for storing an upstream part of the gastrointestinal implant device 200, an inner sheath 1226 positioned inside the outer sheath and extending toward a downstream end of the delivery system 2600 beyond the outer sheath, a release mechanism for releasing the anchor 208 from the outer sheath 1202, and a sleeve release mechanism 1224 for releasing the downstream end of the sleeve 202.
摘要翻译：要解决的问题：提供递送系统和递送组件，其递送用于限制消化系统的特定部分中的食品吸收的装置。解决方案：输送系统2600胃肠道输注装置200胃肠输送。胃肠道植入装置200设置有：锚固在十二指肠中的锚固件208延伸超过Treitz的韧带，并将该装置固定在十二指肠中; 以及用于限制十二指肠中营养素的吸收的无支撑的柔性套筒202。输送系统2600包括用于存储胃肠植入装置200的上游部分的外护套1202，位于外护套内部并且朝向输送系统2600的下游端延伸超过外护套的内护套1226，用于释放的释放机构来自外护套1202的锚定件208和用于释放套筒202的下游端的套筒释放机构1224.（C）2013，JPO和INPIT

5. 发明专利

JP2012152576A Bariatric sleeve 有权
标题翻译： BARIATRIC SLEEVE
公开(公告)号：JP2012152576A
公开(公告)日：2012-08-16
申请号：JP2012088087
申请日：2012-04-09
申请人： Gi Dynamics Inc , ジーアイ・ダイナミックス・インコーポレーテッドGi Dynamics,Inc.
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61F2/00 , A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/00867 , A61B2017/0419 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039
摘要： PROBLEM TO BE SOLVED: To provide a device that employs an inhibitory sleeve within digestive canal so as to limit food absorption in specific portions of the digestive canal and give a morbidly obese patient a negative feedback for improving an eating habit.SOLUTION: A gastrointestinal implant device includes a flexible sleeve 202 composed of a thin and flexible material and unsupported at distal end so that it opens at both ends thereof, extends into the intestinum, limits absorption of nutrients within the intestinum, and can shrinkable in small capacity within the intestinum and a self-expandable and shrinkable anchor 208 connected to a proximal end of the sleeve 202. The anchor 208 has a needle-shaped projection 210 with a structure suitable for insertion into muscle issues and arranged in a direction suitable for the insertion into the muscle issues when the anchor 208 extending from its outer surface is extended and anchors the proximal end of the sleeve 202 within the digestive canal.
摘要翻译：要解决的问题：提供一种在消化道内采用抑制性套管的装置，以限制消化道特定部位的食物吸收，并使病态肥胖的患者具有改善饮食习惯的负面反馈。解决方案：胃肠道植入装置包括由薄且柔性材料构成的柔性套管202，并且在远端不支撑，使得其两端开口，延伸到肠内，限制肠内营养物的吸收，并且可以在肠内以小容量收缩，以及连接到套筒202的近端的自膨胀和收缩的锚固件208.锚固件208具有针状突起210，其具有适于插入肌肉问题并且沿着方向布置的方向适合于当从其外表面延伸的锚定件208延伸并将套筒202的近端锚固在消化道内时插入到肌肉问题中。版权所有（C）2012，JPO＆INPIT

6. 发明申请

WO2004049982A9 BARIATRIC SLEEVE 审中-公开
公开(公告)号：WO2004049982A9
公开(公告)日：2004-07-29
申请号：PCT/US0338238
申请日：2003-12-02
申请人： GI DYNAMICS INC , LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
IPC分类号： A61B17/04 , A61B17/06 , A61F2/00 , A61F2/04 , A61F5/00
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/00867 , A61B2017/0419 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039
摘要： Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.
摘要翻译：介绍了消化系统特定部位限制食品吸收的方法和装置。胃肠装置锚定在胃中，延伸超过Treitz的韧带。所有从胃排出的食物都通过设备进行漏斗。胃肠装置包括用于将装置固定到胃的锚固件和柔性套管，以限制十二指肠中的营养物质的吸收。锚固体可折叠用于内窥镜递送和移除。

7. 发明申请

WO2004049982B1 BARIATRIC SLEEVE 审中-公开
公开(公告)号：WO2004049982B1
公开(公告)日：2004-12-16
申请号：PCT/US0338238
申请日：2003-12-02
申请人： GI DYNAMICS INC , LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
IPC分类号： A61B17/04 , A61B17/06 , A61F2/00 , A61F2/04 , A61F5/00 , A61F2/06
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/00867 , A61B2017/0419 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039
摘要： Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device (200) is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor (208) for anchoring the device to the stomach and a flexible sleeve (202) to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.
摘要翻译：介绍了限制消化系统特定部位食品吸收的方法和装置。胃肠道植入装置（200）被锚定在胃中并延伸超过Treitz的韧带。所有离开胃的食物都通过设备进行漏斗。胃肠装置包括用于将装置固定到胃的锚固件（208）和用于限制十二指肠中的营养物吸收的柔性套筒（202）。锚固体可折叠用于内窥镜递送和移除。

8. 发明申请

WO2004049982A3 BARIATRIC SLEEVE 审中-公开
公开(公告)号：WO2004049982A3
公开(公告)日：2004-10-14
申请号：PCT/US0338238
申请日：2003-12-02
申请人： GI DYNAMICS INC , LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
发明人： LEVINE ANDY H , CVINAR JOHN F , MELANSON DAVE , MEADE JOHN C
IPC分类号： A61B17/04 , A61B17/06 , A61F2/00 , A61F2/04 , A61F5/00 , A61F2/06
CPC分类号： A61F5/0076 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/1114 , A61B2017/00238 , A61B2017/00867 , A61B2017/0419 , A61B2017/061 , A61F2/04 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2/95 , A61F5/0089 , A61F2002/044 , A61F2002/045 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039
摘要： Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device (200) is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor (208) for anchoring the device to the stomach and a flexible sleeve (202) to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.
摘要翻译：介绍了限制消化系统特定部位食品吸收的方法和设备。胃肠植入装置（200）锚定在胃中并延伸超过Treitz韧带。所有排出胃部的食物都通过装置输送。胃肠装置包括用于将装置锚定到胃上的锚定件（208）和用于限制十二指肠内营养物质吸收的柔性套筒（202）。该锚可折叠用于内窥镜递送和移除。

9. 发明申请

WO2004087014A3 ANTI-OBESITY DEVICES 审中-公开
标题翻译：抗菌装置
公开(公告)号：WO2004087014A3
公开(公告)日：2005-01-27
申请号：PCT/US2004009269
申请日：2004-03-26
申请人： GI DYNAMICS INC , LEVINE ANDY H , CVINAR JOHN F , MEADE JOHN C
发明人： LEVINE ANDY H , CVINAR JOHN F , MEADE JOHN C
IPC分类号： A61F2/04 , A61F5/00
CPC分类号： A61F5/0076
摘要： A restrictive device (216) implanted in the upper part of the stomach, selectively divides the stomach into two chambers (220, 222), effectively reducing the size of the stomach immediately available for the uptake of food. The restrictive device also includes an aperture (218), limiting the rate at which food can pass from the esophagus portion of the stomach into the intestine. Being removable, the device permits a physician to change the size of the opening in a minimally invasive manner by replacing a removable member with another member having an aperture of a different size and/or shape. The restrictive device can also be combined with an elongated tube (302), or sleeve to selectively bypass the stomach, a portion of the intestine, or a combination of bypassing both the stomach and a portion of the intestine, allowing a physician to endoscopically create an equivalent to the Roux-en-y weight loss procedure.
摘要翻译：植入胃的上部的限制性装置（216）选择性地将胃分成两个腔室（220,222），从而有效地减小了立即可用于摄取食物的胃的尺寸。限制装置还包括孔（218），其限制食物可以从胃的食道部分进入肠的速度。该装置可移动，允许医师通过用具有不同尺寸和/或形状的孔的另一构件替换可移除构件，以微创方式改变开口的尺寸。限制性装置还可以与细长管（302）或套管组合以选择性地绕过胃，肠的一部分或绕过胃和肠的一部分的组合，允许医师内窥镜地产生相当于Roux-en-y减肥程序。

10. 发明申请

WO2004087233A3 SLEEVE FOR DELAYED INTRODUCTION OF ENZYMES INTO THE INTESTINE 审中-公开
标题翻译：将酶延迟引入INTESTINE的SLEEVE
公开(公告)号：WO2004087233A3
公开(公告)日：2004-12-16
申请号：PCT/US2004009448
申请日：2004-03-26
申请人： GI DYNAMICS INC , LEVINE ANDY H , MEADE JOHN C
发明人： LEVINE ANDY H , MEADE JOHN C
IPC分类号： A61F5/00 , A61M5/32 , A61F2/04
CPC分类号： A61F5/0076
摘要： An elongated tube (122) is configured to carry digestive enzymes from the point at which they enter the duodenum, and deposit them downstream into a distal portion of the intestine, such as the distal jejunum, several feet down. This delays the breakdown and subsequent digestion of food. The proximal end of the tube can be secured to the hepatopancreatic ampulla, below the common bile duct using an anchor (260), such as a stent-like device. The tube can include an elongated flexible sleeve (122) coupled at its proximal end to an anchor. The anchor is attached to the hepatopancreatic ampulla and the sleeve is then draped distally, through the intestines. Natural peristalsis carries the enzymes through the tube distally. The enzymes then exit the tube and mix with the chyme further down stream than is normal.
摘要翻译：细长管（122）被配置为从进入十二指肠的点携带消化酶，并将它们下游沉积到肠的远端部分，例如几英尺的远端空肠。这会延迟食物的分解和随后的消化。管的近端可以使用诸如支架样装置的锚固件（260）固定到肝胰胆管下方的胆总管下方。管可以包括在其近端处连接到锚的细长柔性套筒（122）。锚固件连接到肝胰腺，并且套管然后通过肠部向远侧覆盖。天然蠕动通过管向远端携带酶。酶然后离开管并与正常进一步下游的食糜混合。

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