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1. 发明授权

US4564373A Method for bubble-free gas feed 失效
标题翻译：无气体进料方法
公开(公告)号：US4564373A
公开(公告)日：1986-01-14
申请号：US357560
申请日：1982-03-12
申请人： Franz J. Schmitz , Rudi Wollbeck , Wolfgang Klein
发明人： Franz J. Schmitz , Rudi Wollbeck , Wolfgang Klein
IPC分类号： B01J10/00 , A61M1/16 , B01F1/00 , B01F3/04 , B01J4/00 , B01J4/04 , C02F1/00 , C02F3/20 , C12M1/04 , C12M1/12 , C12M3/06 , B01D53/22
CPC分类号： C12M29/04 , B01F3/04439 , B01J4/04 , C02F3/208 , C12M23/24 , C12M29/06 , Y02W10/15
摘要： A method for the bubble-free feed of gaseous reactants of a chemical and/or biological reaction into a liquid reaction medium, characterized by filling the pores of a porous polymer membrane with the reaction medium, providing one side of the porous polymer membrane with the gaseous reactants, and immersing the other side of the porous polymer membrane into the liquid reaction medium. The pressure of the gaseous reactants should lie below the bubble pressure determined for the reaction medium, but be at least so great that the liquid reaction medium does not pass through the porous polymer membrane to the gas side. Preferred parameters include relative pore volume between 50 and 90%; maximal pore diameter between 0.2 and 3 .mu.m; and disposing the porous polymer membrane in the form of a flat membrane, tube or hollow filaments.
摘要翻译：一种用于将化学和/或生物反应的气态反应物无气泡地进料到液体反应介质中的方法，其特征在于用反应介质填充多孔聚合物膜的孔，提供多孔聚合物膜的一侧与气态反应物，并将多孔聚合物膜的另一侧浸入液体反应介质中。气态反应物的压力应低于为反应介质确定的气泡压力，但至少要使液体反应介质不能通过多孔聚合物膜到气体侧。优选的参数包括50-90％的相对孔体积; 0.2〜3μm的最大孔径; 并且将多孔聚合物膜设置为平膜，管或中空丝的形式。

2. 发明授权

US5126053A Method for manufacturing hollow fiber piles 失效
标题翻译：制造中空纤维桩的方法
公开(公告)号：US5126053A
公开(公告)日：1992-06-30
申请号：US656818
申请日：1991-02-15
申请人： Klaus Schneider , Rudi Wollbeck , Thomas Zang
发明人： Klaus Schneider , Rudi Wollbeck , Thomas Zang
IPC分类号： B01D53/22 , B01D19/00 , B01D63/02 , B01D63/04
CPC分类号： B01D19/0031 , B01D63/021 , B01D63/026 , B01D63/043
摘要： In a method for manufacturing hollow fiber piles, at least one hollow fiber strand is wound spirally onto a rotating drum having a polygonal cross section to form superimposed hollow fiber layers thereon, forming a hollow fiber roll on the drum. Once the desired number of hollow fiber layers has been formed on the rotating drum, segments of a desired shape are separated from substantially planar regions of the hollow fiber roll. Simultaneously, or immediately following this separation, adjacent end regions of the hollow fibers are connected with one another at least spotwise.
摘要翻译：在制造中空纤维桩的方法中，至少一根中空纤维股线螺旋地卷绕到具有多边形横截面的旋转鼓上，以在其上形成叠置的中空纤维层，在滚筒上形成中空纤维卷。一旦所需数量的中空纤维层已经形成在旋转的滚筒上，所需形状的部分与中空纤维辊的基本平坦的区域分离。同时或紧随该分离之后，中空纤维的相邻端部区域至少相互连接。

3. 发明授权

US4480683A Arrangement for heat and mass transfer by means of hollow fibers 失效
标题翻译：通过中空纤维进行热和质量传递的布置
公开(公告)号：US4480683A
公开(公告)日：1984-11-06
申请号：US289512
申请日：1981-08-03
申请人： Rudi Wollbeck , Thomas Zang
发明人： Rudi Wollbeck , Thomas Zang
IPC分类号： B01D53/22 , B01D63/02 , B01D63/04 , F28F11/00
CPC分类号： B01D53/22 , B01D63/02 , B01D63/043 , B01D2313/04 , B01D2313/38 , B01D2313/44 , B01D2317/04
摘要： Arrangement for heat and/or mass transfer between a minimum of two liquids, effected by means of hollow fibers, the open ends of which are imbedded in a casting compound and which hollow fibers are located in the form of hollow fiber modules within a housing, wherein an intermediate ring and gaskets are provided between the housing and the casting compound beds of the hollow fiber module. A bore in the housing allows in case of a defective gasket that leaking liquid may drain to the outside, whereby short circuiting between the different liquid chambers of the housing will be prevented. The intermediate ring may be present as lose component or may, also, be fixedly connected to the face plates of the housing or the housing jacket. A plurality of hollow fiber modules may be arranged within a common housing. The hollow fiber module may be surrounded by a perforated supporting tube. The arrangement is particularly suitable for cross-flow filtration.
摘要翻译：通过中空纤维实现的最少两种液体之间的热和/或质量传递的布置，其开口端嵌入铸塑料中，并且中空纤维以壳体内的中空纤维模块的形式定位，其中在所述壳体和所述中空纤维模块的铸造复合床之间设置有中间环和垫圈。壳体中的孔允许在泄漏的液体可能泄漏到外部的缺陷垫圈的情况下，从而防止壳体的不同液体室之间的短路。中间环可以作为失去部件存在，或者也可以固定地连接到壳体或壳体护套的面板。多个中空纤维模块可以布置在公共壳体内。中空纤维模块可以被穿孔的支撑管包围。该装置特别适用于交叉流过滤。

4. 发明授权

US06410307B1 Membrane module for testing active substances at cells 失效
标题翻译：用于测试细胞活性物质的膜模块
公开(公告)号：US06410307B1
公开(公告)日：2002-06-25
申请号：US09936264
申请日：2001-11-21
申请人： Herma Glockner , Horst-Dieter Lemke , Friedrich Hauck , Christoph Zimmerer , Rudi Wollbeck
发明人： Herma Glockner , Horst-Dieter Lemke , Friedrich Hauck , Christoph Zimmerer , Rudi Wollbeck
IPC分类号： C12M134
CPC分类号： C12Q1/025 , B01J2219/00907 , C12M23/04 , C12M25/02 , C12M29/04
摘要： Membrane module for testing active substances in cells with an interior chamber (2) which is limited by a lid (3), a bottom (4), and a side wall (5) and a system of first capillary membranes (6) and a system of second capillary membranes (11) located therein and possibly additional systems of capillary membranes, whereby the capillary membranes in interior chamber (2) are arranged in at least one flat layer parallel to bottom (4) and in interior chamber (2) in the extracapillary space a cell culture chamber is formed around the capillary membranes, whereby the capillary membranes have a lumen that can be filled with a fluid, are passing with at least one of its ends through the side wall (5) of interior chamber (2) and are embedded at this end separated by systems in a casting material (9, 10) so that interior chamber (2) is sealed fluid-tight from the outside, and whereby the capillary membranes of each system are in a fluid connection with their lumens with an inlet device (7) and/or an outlet device (8), and whereby interior chamber (2) has a volume between 0.1 and 5 cm3.
摘要翻译：用于测试具有由盖（3），底部（4）和侧壁（5）以及第一毛细管（6）和第一毛细管（6）的系统限制的内部室（2）的细胞中的活性物质的膜模块第二毛细管膜（11）的系统，以及可能的另外的毛细管膜系统，其中内室（2）中的毛细管膜被布置在平行于底部（4）和内室（2）中的至少一个平坦层中毛细血管间隙形成在毛细血管膜周围的细胞培养室，由此毛细管膜具有可填充流体的内腔，其至少一端通过内腔（2）的侧壁（5）），并且在该端部嵌入在铸造材料（9,10）中的系统分开，使得内部室（2）从外部流体密封，并且由此每个系统的毛细管膜与它们的流体连接具有入口装置（7）和/或的流明出口装置（8），并且由此内部室（2）具有在0.1和5cm 3之间的体积。

5. 发明授权

US5032269A Hollow fiber module 失效
标题翻译：中空纤维模块
公开(公告)号：US5032269A
公开(公告)日：1991-07-16
申请号：US353068
申请日：1989-05-17
申请人： Rudi Wollbeck , Thomas Zang
发明人： Rudi Wollbeck , Thomas Zang
IPC分类号： B01D46/54 , B01D63/02 , B01D63/04 , F28F21/06
CPC分类号： F28F21/062 , B01D63/021 , B01D63/024 , B01D63/04
摘要： A hollow fiber module with at least one bundle of hollow fibers made in a U shape, in which each hollow fiber bundle comprises at least two part bundles of different average lengths, the hollow fibers arranged essentially in the form of layers at least in the region of the bend of the U shape, the layers extending substantially parallel to the longitudinal axis of the module, the longitudinal axes of the layers and the longitudinal axis of the module approximately coinciding and the layers forming an angle between them when viewed longitudinally. An apparatus and process for making the hollow fiber module are also disclosed.
摘要翻译：一种中空纤维模块，其具有制成U形的至少一束中空纤维，其中每个中空纤维束包括不同平均长度的至少两部分束，中空纤维至少在该区域中基本上以层的形式排列 U形的弯曲部分，这些层基本上平行于模块的纵向轴线延伸，层的纵向轴线和模块的纵向轴线大致重合，并且当纵向观察时，这些层在它们之间形成一个角度。还公开了一种用于制造中空纤维模块的设备和方法。

6. 发明授权

US5160673A Hollow fiber module 失效
标题翻译：中空纤维模块
公开(公告)号：US5160673A
公开(公告)日：1992-11-03
申请号：US665490
申请日：1991-03-05
申请人： Rudi Wollbeck , Thomas Zang
发明人： Rudi Wollbeck , Thomas Zang
IPC分类号： B01D46/54 , B01D63/02 , B01D63/04 , F28F21/06
CPC分类号： F28F21/062 , B01D63/021 , B01D63/024 , B01D63/04
摘要： A hollow fiber module with at least one bundle of hollow fibers made in a U shape, in which each hollow fiber bundle comprises at least two part bundles of different average lengths, the hollow fibers arranged essentially in the form of layers at least in the region of the bend of the U shape, the layers extending substantially parallel to the longitudinal axis of the module, the longitudinal axes of the layers and the longitudinal axis of the module approximately coinciding and the layers forming an angle between them when viewed longitudinally. An apparatus and process for making the hollow fiber module are also disclosed.
摘要翻译：一种中空纤维模块，其具有制成U形的至少一束中空纤维，其中每个中空纤维束包括不同平均长度的至少两部分束，中空纤维至少在该区域中基本上以层的形式排列 U形的弯曲部分，这些层基本上平行于模块的纵向轴线延伸，层的纵向轴线和模块的纵向轴线大致重合，并且当纵向观察时，这些层在它们之间形成一个角度。还公开了一种用于制造中空纤维模块的设备和方法。

7. 发明授权

US4961464A Mass and/or heat exchanger with thermal expansion relief 失效
标题翻译：具有热膨胀释放的质量和/或热交换器
公开(公告)号：US4961464A
公开(公告)日：1990-10-09
申请号：US408267
申请日：1989-09-18
申请人： Rudi Wollbeck , Thomas Zang
发明人： Rudi Wollbeck , Thomas Zang
IPC分类号： F28F9/04 , B01D63/02 , F16J15/02 , F28F9/02 , F28F21/06
CPC分类号： B01D63/02 , F16J15/021 , F28F21/062 , F28F9/0241 , B01D2313/13 , B01D2313/38 , F28F2265/26 , Y10S165/059
摘要： A mass and/or heat exchanger includes at least one bundle of capillaries, the ends of which are embedded in a casting composition, and a housing in which the capillaries with the casting composition are arranged in such a way that the casting composition represents a liquid-tight isolation between the lumens of the capillaries and the space outside the capillaries. An elastic element which compensates for differences in changes of length of the at least one bundle of capillaries and the housing, is provided between the casting composition and the housing.
摘要翻译：质量和/或热交换器包括至少一束毛细管，其末端包埋在铸造组合物中，以及壳体，其中具有铸塑组合物的毛细管以这样的方式布置，使得铸塑组合物代表液体在毛细血管的流明和毛细血管之外的空间之间的隔离。在铸造组合物和壳体之间提供补偿至少一束毛细管和壳体的长度变化的差异的弹性元件。

8. 发明授权

US4740344A Method for the production of heat and/or fluid exchangers that contain tubes 失效
标题翻译：用于生产含有管的热和/或流体交换器的方法
公开(公告)号：US4740344A
公开(公告)日：1988-04-26
申请号：US751121
申请日：1985-07-02
申请人： Rudi Wollbeck , Thomas Zang , Dirk A. Klarenberg , Hugo P. Korstanje
发明人： Rudi Wollbeck , Thomas Zang , Dirk A. Klarenberg , Hugo P. Korstanje
IPC分类号： B01D63/02 , B01D63/06 , B29C45/14 , F28F21/06 , B29C45/73 , B29C65/02
CPC分类号： B29C45/14336 , B01D63/02 , B01D63/022 , B01D63/061 , B29C45/14598 , B29C45/14614 , F28F21/062 , F28F21/067 , Y10S264/65
摘要： The invention comprises a method and apparatus wherein an insert, preferably made of plastic and preferably allowing a melt-on bonding with the tubes and whose floor has a traversing opening for each tube, is inserted into the first part of the injection mold (top mold or bottom mold) as a positioning element for the tubes in such a manner that the insert is at least partially locked or secured into the first part of the injection mold. A tube is then placed in each opening of the insert. A mandrel is then placed in each tube, whereupon the injection mold is locked in such a manner that, if necessary, the mandrels are locked into the second part of the injection mold (bottom mold or top mold). A molten thermoplastic material is then injected, via a sprue provided in the injection mold, into a cavity formed by the injection mold, the insert and the tube ends. The parts of the injection mold are separated after cooling of the thermoplastic material, which is maintained under pressure during the cooling at least initially. The mandrels are then removed and the tubes bonded to the insert by the thermoplastic material are removed from the first part of the injection mold and, if appropriate, the free ends of the tubes are also bonded to a second insert by means of the injection mold.
摘要翻译：本发明包括一种方法和装置，其中优选地由塑料制成并且优选地允许与管熔融结合并且其地板具有用于每个管的横向开口的插入件插入注射模具的第一部分（顶模具或底模）作为用于管的定位元件，使得插入件至少部分地被锁定或固定到注射模具的第一部分中。然后将管放置在插入物的每个开口中。然后将心轴放置在每个管中，由此注射模具被锁定，使得如果需要，将心轴锁定到注射模具（底部模具或顶部模具）的第二部分中。然后通过设置在注射模具中的浇口将熔融的热塑性材料注入由注射模具形成的空腔中，插入件和管端部。注射模具的部件在冷却热塑性材料之后分离，热塑性材料在冷却期间至少保持在最初的压力下。然后去除心轴，并且通过热塑性材料结合到插入件的管从注射模具的第一部分移除，并且如果合适的话，管的自由端也通过注射模具结合到第二插入件。

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