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1. 发明申请

US20120215273A1 METHOD AND APPARATUS FOR CONCURRENT ATRIO-VENTRICULAR ANTI-TACHYCARDIA PACING 有权
标题翻译：相关性ATRIO-VENTRICULAR ANTI-TACHYCARDIA PACING的方法和装置
公开(公告)号：US20120215273A1
公开(公告)日：2012-08-23
申请号：US13457630
申请日：2012-04-27
申请人： Dan Li , Jaeho Kim , Joseph M. Bocek
发明人： Dan Li , Jaeho Kim , Joseph M. Bocek
IPC分类号： A61N1/365
CPC分类号： A61N1/3621 , A61N1/368 , A61N1/3688
摘要： An implantable medical device delivers anti-tachyarrhythmia therapies including anti-tachycardia pacing (ATP). If a detected tachyarrhythmia is classified as a type suitable for treatment using ATP, the implantable medical device selects one of an atrial ATP (A-ATP) mode, a ventricular ATP (V-ATP) mode, and a concurrent atrio-ventricular ATP (concurrent AV-ATP) mode according to the characteristics of the detected tachyarrhythmia. The concurrent ATP mode is an ATP mode during which the atrial pacing pulses and the ventricular pacing pulses are delivered concurrently. In one embodiment, the concurrent AV-ATP mode includes a synchronized atrio-ventricular ATP (synchronized AV-ATP) mode during which atrial and ventricular pacing pulses are delivered synchronously and an independent atrio-ventricular ATP (independent AV-ATP) mode during which atrial and ventricular pacing pulses are delivered concurrently but timed independently.
摘要翻译：植入式医疗装置提供抗心律失常疗法，包括抗心动过速起搏（ATP）。如果检测到的快速性心律失常被分类为适合于使用ATP治疗的类型，则可植入医疗装置选择心房ATP（A-ATP）模式，心室ATP（V-ATP）模式和并发心室ATP 并发AV-ATP）模式，根据检测到的快速性心律失常的特点。并发ATP模式是ATP模式，其中心房起搏脉冲和心室起搏脉冲同时传递。在一个实施方案中，并发的AV-ATP模式包括同步的心房ATP（同步的AV-ATP）模式，其中同步递送心房和心室起搏脉冲以及独立的心房ATP（独立的AV-ATP）模式，在此期间心房和心室起搏脉冲同时传递，但可以独立计时。

2. 发明授权

US08170669B2 Method and apparatus for concurrent atrio-ventricular anti-tachycardia pacing 有权
标题翻译：并发房室性心动过速起搏方法及装置
公开(公告)号：US08170669B2
公开(公告)日：2012-05-01
申请号：US12234840
申请日：2008-09-22
申请人： Dan Li , Jaeho Kim , Joseph M. Bocek
发明人： Dan Li , Jaeho Kim , Joseph M. Bocek
IPC分类号： A61N1/365
CPC分类号： A61N1/3621 , A61N1/368 , A61N1/3688
摘要： An implantable medical device delivers anti-tachyarrhythmia therapies including anti-tachycardia pacing (ATP). If a detected tachyarrhythmia is classified as a type suitable for treatment using ATP, the implantable medical device selects one of an atrial ATP (A-ATP) mode, a ventricular ATP (V-ATP) mode, and a concurrent atrio-ventricular ATP (concurrent AV-ATP) mode according to the characteristics of the detected tachyarrhythmia. The concurrent ATP mode is an ATP mode during which the atrial pacing pulses and the ventricular pacing pulses are delivered concurrently. In one embodiment, the concurrent AV-ATP mode includes a synchronized atrio-ventricular ATP (synchronized AV-ATP) mode during which atrial and ventricular pacing pulses are delivered synchronously and an independent atrio-ventricular ATP (independent AV-ATP) mode during which atrial and ventricular pacing pulses are delivered concurrently but timed independently.
摘要翻译：植入式医疗装置提供抗心律失常疗法，包括抗心动过速起搏（ATP）。如果检测到的快速性心律失常被分类为适合于使用ATP治疗的类型，则可植入医疗装置选择心房ATP（A-ATP）模式，心室ATP（V-ATP）模式和并发心室ATP 并发AV-ATP）模式，根据检测到的快速性心律失常的特点。并发ATP模式是ATP模式，其中心房起搏脉冲和心室起搏脉冲同时传递。在一个实施方案中，并发的AV-ATP模式包括同步的心房ATP（同步的AV-ATP）模式，其中同步递送心房和心室起搏脉冲以及独立的心房ATP（独立的AV-ATP）模式，在此期间心房和心室起搏脉冲同时传递，但可以独立计时。

3. 发明授权

US07904142B2 Self-adjusting ECG morphological feature correlation threshold 有权
标题翻译：自适应心电图形态特征相关阈值
公开(公告)号：US07904142B2
公开(公告)日：2011-03-08
申请号：US11749283
申请日：2007-05-16
申请人： Jaeho Kim , Joseph M. Bocek , Dan Li
发明人： Jaeho Kim , Joseph M. Bocek , Dan Li
IPC分类号： A61B5/0402
CPC分类号： A61B5/0422 , A61N1/3622 , A61N1/3931 , A61N1/3962
摘要： An apparatus comprising an implantable cardiac signal sensing circuit configured for sensing an intrinsic cardiac signal, a memory to store a template of a morphology of normal atrial-ventricular conduction, and a controller that includes a tachyarrhythmia detection circuit and a correlation circuit. The tachyarrhythmia detection circuit is configured for detecting a rhythm with elevated ventricular rate using the sensed intrinsic cardiac signal. The correlation circuit is configured for iteratively calculating a correlation between the sensed intrinsic cardiac signal and the template, and comparing the calculated correlation to a variable correlation threshold to determine whether the detected rhythm correlates to the template. The apparatus also includes a therapy circuit configured for inhibiting a ventricular tachycardia therapy when the detected rhythm correlates to the template. Other apparatuses and methods are described.
摘要翻译：一种装置，包括被配置为感测本征心脏信号的可植入心脏信号感测电路，存储器以存储正常心室传导形态的模板，以及包括快速性心律失常检测电路和相关电路的控制器。快速心律失常检测电路被配置为使用感测到的本征心脏信号来检测具有升高的心室率的节律。相关电路被配置为迭代地计算所感测的本征心脏信号与模板之间的相关性，并将所计算的相关性与可变相关阈值进行比较，以确定检测到的节律是否与模板相关。该装置还包括治疗电路，其被配置为当检测到的节律与模板相关时抑制室性心动过速治疗。描述其他设备和方法。

4. 发明授权

US08437849B2 Method and apparatus for atrial pacing during tachyarrhythmia 有权
标题翻译：快速性心律失常期心房起搏的方法和装置
公开(公告)号：US08437849B2
公开(公告)日：2013-05-07
申请号：US11668627
申请日：2007-01-30
申请人： Jaeho Kim , Joseph M. Bocek , Dan Li
发明人： Jaeho Kim , Joseph M. Bocek , Dan Li
IPC分类号： A61N1/372 , A61N1/39
CPC分类号： A61N1/3962 , A61B5/0452 , A61B5/04525 , A61B5/0464 , A61B5/7264 , A61N1/3925
摘要： An implantable cardioverter/defibrillator (ICD) delivers atrial pacing under several scenarios during a tachyarrhythmia episode that is detected using a ventricular rate. In various embodiments, the atrial pacing terminates the detected tachyarrhythmia and/or enhances the classification of the detected tachyarrhythmia, thus avoiding ineffective and/or unnecessary delivery of a ventricular anti-tachyarrhythmia therapy when the detected tachyarrhythmia has a supraventricular origin.
摘要翻译：植入式心律转复除颤器（ICD）在使用心室率检测到的快速性心律失常发作期间在几种情况下提供心房起搏。在各种实施方案中，心房起搏终止所检测到的快速性心律失常和/或增强检测到的快速性心律失常的分类，从而避免了当检测到的快速性心律失常具有室上性起源时，无效和/或不必要地输送室性抗快速性心律失常治疗。

5. 发明授权

US08301244B2 Sustaining ventricular tachycardia detection 有权
标题翻译：维持室性心动过速检测
公开(公告)号：US08301244B2
公开(公告)日：2012-10-30
申请号：US12552614
申请日：2009-09-02
申请人： Jaeho Kim , Dan Li , Joseph M. Bocek
发明人： Jaeho Kim , Dan Li , Joseph M. Bocek
IPC分类号： A61B5/046
CPC分类号： A61N1/3621 , A61B5/0464 , A61N1/365 , A61N1/3962
摘要： An apparatus comprises an implantable ventricular depolarization sensing circuit configured to provide a sensed ventricular depolarization signal, a timer circuit configured to provide a ventricular time interval between ventricular depolarizations, and a controller circuit communicatively coupled to the ventricular depolarization sensing circuit and the timer circuit. The controller circuit includes a ventricular tachycardia (VT) detection circuit configured to declare an episode of VT when a number of accelerated beats are detected, calculate a hysteresis VT detection threshold interval, and deem whether the episode of VT persists using the hysteresis VT detection threshold interval.
摘要翻译：一种装置包括可植入心室去极化感测电路，其被配置为提供感测到的心室去极化信号，定时器电路，其被配置为提供心室去极化之间的心室时间间隔，以及通信地耦合到心室去极化感测电路和定时器电路的控制器电路。所述控制器电路包括心室性心动过速（VT）检测电路，其被配置为当检测到多个加速搏动时声明VT的发作，计算滞后VT检测阈值间隔，并且使用滞后VT检测阈值来确定VT的发作是否持续间隔。

6. 发明授权

US08260409B2 Self-adjusting ECG morphological feature correlation threshold 有权
标题翻译：自适应心电图形态特征相关阈值
公开(公告)号：US08260409B2
公开(公告)日：2012-09-04
申请号：US13018682
申请日：2011-02-01
申请人： Jaeho Kim , Joseph M. Bocek , Dan Li
发明人： Jaeho Kim , Joseph M. Bocek , Dan Li
IPC分类号： A61B5/0402
CPC分类号： A61B5/0422 , A61N1/3622 , A61N1/3931 , A61N1/3962
摘要： An apparatus comprises first and second sensing circuits, a template generator circuit, and a correlation circuit. The correlation circuit is configured to identify a first fiducial position in a third cardiac signal sensed using the first sensing circuit during a detected rhythm with elevated ventricular rate, align the template correlation features and the correlation features of a fourth cardiac signal using the first fiducial position, calculate a correlation using the correlation features of the template and the correlation features of the fourth cardiac signal, and iteratively searching for a replacement to the first fiducial position in the third cardiac signal according to the calculated correlation.
摘要翻译：一种装置包括第一和第二感测电路，模板发生器电路和相关电路。相关电路被配置为在检测到的具有升高的心室率的节律期间识别在使用第一感测电路感测的第三心脏信号中的第一基准位置，使用第一基准位置对准模板相关特征和第四心脏信号的相关特征使用模板的相关特征和第四心脏信号的相关特征来计算相关性，并且根据所计算的相关性迭代地搜索第三心脏信号中的第一基准位置的替换。

7. 发明申请

US20100057152A1 SUSTAINING VENTRICULAR TACHYCARDIA DETECTION 有权
标题翻译：持续性静脉卡车检测
公开(公告)号：US20100057152A1
公开(公告)日：2010-03-04
申请号：US12552614
申请日：2009-09-02
申请人： Jaeho Kim , Dan Li , Joseph M. Bocek
发明人： Jaeho Kim , Dan Li , Joseph M. Bocek
IPC分类号： A61N1/365 , A61N1/39 , A61B5/0464
CPC分类号： A61N1/3621 , A61B5/0464 , A61N1/365 , A61N1/3962
摘要： An apparatus comprises an implantable ventricular depolarization sensing circuit configured to provide a sensed ventricular depolarization signal, a timer circuit configured to provide a ventricular time interval between ventricular depolarizations, and a controller circuit communicatively coupled to the ventricular depolarization sensing circuit and the timer circuit. The controller circuit includes a ventricular tachycardia (VT) detection circuit configured to declare an episode of VT when a number of accelerated beats are detected, calculate a hysteresis VT detection threshold interval, and deem whether the episode of VT persists using the hysteresis VT detection threshold interval.
摘要翻译：一种装置包括可植入心室去极化感测电路，其被配置为提供感测到的心室去极化信号，定时器电路，其被配置为提供心室去极化之间的心室时间间隔，以及通信地耦合到心室去极化感测电路和定时器电路的控制器电路。所述控制器电路包括心室性心动过速（VT）检测电路，其被配置为当检测到多个加速搏动时声明VT的发作，计算滞后VT检测阈值间隔，并且使用滞后VT检测阈值来确定VT的发作是否持续间隔。

8. 发明申请

US20090099616A1 METHOD AND APPARATUS FOR CONCURRENT ATRIO-VENTRICULAR ANTI-TACHYCARDIA PACING 有权
标题翻译：相关性ATRIO-VENTRICULAR ANTI-TACHYCARDIA PACING的方法和装置
公开(公告)号：US20090099616A1
公开(公告)日：2009-04-16
申请号：US12234840
申请日：2008-09-22
申请人： Dan Li , Jaeho Kim , Joseph M. Bocek
发明人： Dan Li , Jaeho Kim , Joseph M. Bocek
IPC分类号： A61N1/365
CPC分类号： A61N1/3621 , A61N1/368 , A61N1/3688
摘要： An implantable medical device delivers anti-tachyarrhythmia therapies including anti-tachycardia pacing (ATP). If a detected tachyarrhythmia is classified as a type suitable for treatment using ATP, the implantable medical device selects one of an atrial ATP (A-ATP) mode, a ventricular ATP (V-ATP) mode, and a concurrent atrio-ventricular ATP (concurrent AV-ATP) mode according to the characteristics of the detected tachyarrhythmia. The concurrent ATP mode is an ATP mode during which the atrial pacing pulses and the ventricular pacing pulses are delivered concurrently. In one embodiment, the concurrent AV-ATP mode includes a synchronized atrio-ventricular ATP (synchronized AV-ATP) mode during which atrial and ventricular pacing pulses are delivered synchronously and an independent atrio-ventricular ATP (independent AV-ATP) mode during which atrial and ventricular pacing pulses are delivered concurrently but timed independently.
摘要翻译：植入式医疗装置提供抗心律失常疗法，包括抗心动过速起搏（ATP）。如果检测到的快速性心律失常被分类为适合于使用ATP治疗的类型，则可植入医疗装置选择心房ATP（A-ATP）模式，心室ATP（V-ATP）模式和并发心室ATP 并发AV-ATP）模式根据检测到的快速性心律失常的特点。并发ATP模式是ATP模式，其中心房起搏脉冲和心室起搏脉冲同时传递。在一个实施方案中，并发的AV-ATP模式包括同步的心房ATP（同步的AV-ATP）模式，其中同步递送心房和心室起搏脉冲以及独立的心房ATP（独立的AV-ATP）模式，在此期间心房和心室起搏脉冲同时传递，但可以独立计时。

9. 发明授权

US08620429B2 Method and apparatus for concurrent atrio-ventricular anti-tachycardia pacing 有权
标题翻译：并发房室性心动过速起搏方法及装置
公开(公告)号：US08620429B2
公开(公告)日：2013-12-31
申请号：US13457630
申请日：2012-04-27
申请人： Dan Li , Jaeho Kim , Joseph M. Bocek
发明人： Dan Li , Jaeho Kim , Joseph M. Bocek
IPC分类号： A61N1/39
CPC分类号： A61N1/3621 , A61N1/368 , A61N1/3688
摘要： An implantable medical device delivers anti-tachyarrhythmia therapies including anti-tachycardia pacing (ATP). If a detected tachyarrhythmia is classified as a type suitable for treatment using ATP, the implantable medical device selects one of an atrial ATP (A-ATP) mode, a ventricular ATP (V-ATP) mode, and a concurrent atrio-ventricular ATP (concurrent AV-ATP) mode according to the characteristics of the detected tachyarrhythmia. The concurrent ATP mode is an ATP mode during which the atrial pacing pulses and the ventricular pacing pulses are delivered concurrently. In one embodiment, the concurrent AV-ATP mode includes a synchronized atrio-ventricular ATP (synchronized AV-ATP) mode during which atrial and ventricular pacing pulses are delivered synchronously and an independent atrio-ventricular ATP (independent AV-ATP) mode during which atrial and ventricular pacing pulses are delivered concurrently but timed independently.
摘要翻译：植入式医疗装置提供抗心律失常疗法，包括抗心动过速起搏（ATP）。如果检测到的快速性心律失常被分类为适合于使用ATP治疗的类型，则可植入医疗装置选择心房ATP（A-ATP）模式，心室ATP（V-ATP）模式和并发心室ATP 并发AV-ATP）模式根据检测到的快速性心律失常的特点。并发ATP模式是ATP模式，其中心房起搏脉冲和心室起搏脉冲同时传递。在一个实施方案中，并发的AV-ATP模式包括同步的心房ATP（同步的AV-ATP）模式，其中同步递送心房和心室起搏脉冲以及独立的心房ATP（独立的AV-ATP）模式，在此期间心房和心室起搏脉冲同时传递，但可以独立计时。

10. 发明申请

US20110130672A1 SELF-ADJUSTING ECG MORPHOLOGICAL FEATURE CORRELATION THRESHOLD 有权
标题翻译：自我调节心电图形态特征相关阈值
公开(公告)号：US20110130672A1
公开(公告)日：2011-06-02
申请号：US13018682
申请日：2011-02-01
申请人： Jaeho Kim , Joseph M. Bocek , Dan Li
发明人： Jaeho Kim , Joseph M. Bocek , Dan Li
IPC分类号： A61B5/0402
CPC分类号： A61B5/0422 , A61N1/3622 , A61N1/3931 , A61N1/3962
摘要： An apparatus comprises first and second sensing circuits, a template generator circuit, and a correlation circuit. The correlation circuit is configured to identify a first fiducial position in a third cardiac signal sensed using the first sensing circuit during a detected rhythm with elevated ventricular rate, align the template correlation features and the correlation features of a fourth cardiac signal using the first fiducial position, calculate a correlation using the correlation features of the template and the correlation features of the fourth cardiac signal, and iteratively searching for a replacement to the first fiducial position in the third cardiac signal according to the calculated correlation.
摘要翻译：一种装置包括第一和第二感测电路，模板发生器电路和相关电路。相关电路被配置为在检测到的具有升高的心室率的节律期间识别在使用第一感测电路感测的第三心脏信号中的第一基准位置，使用第一基准位置对准模板相关特征和第四心脏信号的相关特征使用模板的相关特征和第四心脏信号的相关特征来计算相关性，并且根据所计算的相关性迭代地搜索第三心脏信号中的第一基准位置的替换。

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