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    • 4. 发明申请
    • ULTRASENSITIVE SPECTROPHOTOMETER
    • 超声波分光光度计
    • WO2006076353A3
    • 2007-01-11
    • PCT/US2006000805
    • 2006-01-11
    • UNIV MISSOURILARSEN DAVID WXU ZHI
    • LARSEN DAVID WXU ZHI
    • G01J3/42G01J3/427
    • G01N21/31G01J3/02G01J3/0224G01J3/0262G01J3/0286G01J3/0291G01J3/42G01J2003/425G01N21/274G01N2021/3137G01N2201/0227G01N2201/0642G01N2201/127
    • The invention concerns spectrophotometer devices that provide for ultrasensitive measurements through a reflection interaction with matter. Embodiments of the invention use sealed housings (112, 600, 700) lacking an internal light source, and reflection based sample and reference cells. In some embodiments a substantially solid thermally conductive housing (600, 700) is used. Oilier features of preferred embodiments include particular reflection based sample and reference cells. A total internal reflection embodiment includes a prism (302, 322, 622a, 623a) including an interaction surface, a detector, a lens that focuses a beam output from the prism onto the detector, and a closed interaction volume having an inlet and an outlet for delivering gas or liquid to the interaction surface. In a specular reflection embodiment, a reflective surface (402, 422) is used. In a diffuse reflection embodiment a matte surface (502, 522) is used and the matte surface produces scattering.
    • 本发明涉及通过与物质的反射相互作用提供超灵敏测量的分光光度计装置。 本发明的实施例使用缺少内部光源的密封壳体(112,600,700)和基于反射的样品和参考单元。 在一些实施例中,使用基本上固体的导热壳体(600,700)。 优选实施方案的更大的特征包括特定的基于反射的样品和参比细胞。 全内反射实施例包括包括相互作用表面的棱镜(302,322,622a,623a),检测器,将从棱镜输出的光束聚焦到检测器上的透镜以及具有入口和出口 用于将气体或液体输送到相互作用表面。 在镜面反射实施例中,使用反射表面(402,422)。 在漫反射实施例中,使用无光泽表面(502,522),并且无光泽表面产生散射。