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1. 发明申请

US20050033281A1 Catheter placement detection system and operator interface 有权
标题翻译：导管放置检测系统和操作界面
公开(公告)号：US20050033281A1
公开(公告)日：2005-02-10
申请号：US10924584
申请日：2004-08-24
申请人： Brett Bowman , Vijay Dhaka , Kenneth Kitlas , Douglas Harrington
发明人： Brett Bowman , Vijay Dhaka , Kenneth Kitlas , Douglas Harrington
IPC分类号： A61B17/42 , A61B17/12 , A61B18/04 , A61B18/12 , A61B18/14 , A61M25/095 , A61B5/04
CPC分类号： A61B18/1492 , A61B2017/4233 , A61B2018/00559 , A61B2018/00875 , A61B2090/065
摘要： A system for facilitating the placement of a catheter within the human body, in a lumen or vessel such as the fallopian tubes, and controlling the catheter after placement. The system coordinates the operation of treatment electrodes on the catheter with informative displays and prompts to an operator, based on information derived from electrical parameters of position detection electrodes on the catheter.
摘要翻译：一种用于促进将导管放置在人体内，管腔或容器（例如输卵管）中并在放置之后控制导管的系统。该系统基于从导管上的位置检测电极的电参数得到的信息，将导管上的治疗电极的操作与信息显示和操作者协调。

2. 发明申请

US20070215163A1 Method and Apparatus for Tubal Occlusion 失效
标题翻译：用于管状闭塞的方法和装置
公开(公告)号：US20070215163A1
公开(公告)日：2007-09-20
申请号：US11752222
申请日：2007-05-22
申请人： Douglas Harrington , Brett Bowman , Peter Breining
发明人： Douglas Harrington , Brett Bowman , Peter Breining
IPC分类号： A61F6/14
CPC分类号： A61B17/12099 , A61B17/12022 , A61B17/12109 , A61B17/12159 , A61B18/1485 , A61B18/1815 , A61B90/39 , A61B2017/003 , A61B2018/00559 , A61B2018/00577 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00738 , A61B2018/00755 , A61B2018/00791 , A61B2018/00815 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1437 , A61B2018/1467 , A61B2090/3925 , A61F6/225
摘要： A device for sterilizing females by occluding the uterotubal junction. The device includes a catheter with a releasable heat generating plug which is used to thermally damage the uterotubal junction and cause it to constrict around the plug, after which the plug is released from the catheter and left in place in the uterotubal junction.
摘要翻译：通过闭塞子宫交界消毒女性的装置。该装置包括具有可释放的发热塞的导管，其用于热损伤子宫交界处并使其在塞子周围收缩，之后将塞从导管释放并留在子宫交界处。

3. 发明授权

US06671393B2 Automated method for image analysis of residual protein 有权
公开(公告)号：US06671393B2
公开(公告)日：2003-12-30
申请号：US10014006
申请日：2001-12-10
申请人： Presley Hays , Michal L. Peri , Douglas Harrington
发明人： Presley Hays , Michal L. Peri , Douglas Harrington
IPC分类号： G06K900
CPC分类号： G01N15/1475 , G01N15/1468 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G06K9/00127 , G06T7/60
摘要： An automated method for evaluating the amount of residual protein levels following treatment of cellular specimens. Particular methods include the measurement of maternal neutrophil alkaline phosphatase after treatment with or without urea or heat, measurement of leukocyte acid phosphatase after treatment with or without tartrate, and measurement of leukocyte esterase after treatment with &agr;-naphthol butyrate with or without fluoride.

4. 发明申请

US20080260233A1 AUTOMATED METHOD FOR IMAGE ANALYSIS OF RESIDUAL PROTEIN 失效
标题翻译：残留蛋白图像分析自动化方法
公开(公告)号：US20080260233A1
公开(公告)日：2008-10-23
申请号：US12102665
申请日：2008-04-14
申请人： Presley Hays , Michal L. Peri , Douglas Harrington
发明人： Presley Hays , Michal L. Peri , Douglas Harrington
IPC分类号： G06K9/00
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method for measuring residual protein in a cellular specimen including obtaining a low magnification image of a candidate object of interest, filtering the candidate object of interest pixels with a low pass filter, morphologically processing the candidate object of interest pixels to identify artifact pixels, identifying the candidate object of interest by eliminating artifact pixels, acquiring a higher magnification image of the subsample for the candidate object of interest, transforming pixels of the higher magnification image in a first color space to a second color space to differentiate higher magnification candidate object of interest pixels from background pixels, identifying an object of interest from the candidate object of interest pixels in the second color space, and determining the optical density of the protein in a cell contained in a subsample, wherein the optical density is indicative of the residual component of a cellular protein.
摘要翻译：一种用于测量细胞样本中残留蛋白质的方法，包括获得感兴趣的候选对象的低倍率图像，利用低通滤波器过滤候选对象像素，在形态上处理候选对象像素以识别伪像，识别通过消除伪影像素来获取所述候选对象，获取用于所述候选对象的子样本的较高放大图像，将第一颜色空间中的较高倍率图像的像素变换为第二颜色空间，以区分感兴趣的较高倍率候选对象从背景像素的像素，从第二颜色空间中的候选对象像素识别感兴趣的对象，以及确定子样本中包含的细胞中的蛋白质的光密度，其中光密度指示残留分量细胞蛋白。

5. 发明授权

US06330349B1 Automated method for image analysis of residual protein 失效
标题翻译：残留蛋白图像分析自动化方法
公开(公告)号：US06330349B1
公开(公告)日：2001-12-11
申请号：US09612022
申请日：2000-07-07
申请人： Presley Hays , Michal L. Peri , Douglas Harrington
发明人： Presley Hays , Michal L. Peri , Douglas Harrington
IPC分类号： G06K900
CPC分类号： G01N15/1475 , G01N15/1468 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G06K9/00127 , G06T7/60
摘要： An automated method for evaluating the amount of residual protein levels following treatment of cellular specimens. Particular methods include the measurement of maternal neutrophil alkaline phosphatase after treatment with or without urea or heat, measurement of leukocyte acid phosphatase after treatment with or without tartrate, and measurement of leukocyte esterase after treatment with &agr;-naphthol butyrate with or without fluoride.
摘要翻译：一种用于评估细胞标本治疗后残留蛋白质水平的自动化方法。具体方法包括用或不用尿素或加热处理后测量母体嗜中性粒细胞碱性磷酸酶，用或不用酒石酸盐处理后测量白细胞酸性磷酸酶，以及在用或不含氟化物的α-萘酚丁酸酯处理后测定白细胞酯酶。

6. 发明授权

US07660449B2 Automated method for image analysis of residual protein 失效
标题翻译：残留蛋白图像分析自动化方法
公开(公告)号：US07660449B2
公开(公告)日：2010-02-09
申请号：US12102665
申请日：2008-04-14
申请人： Presley Hays , Michal L. Peri , Douglas Harrington
发明人： Presley Hays , Michal L. Peri , Douglas Harrington
IPC分类号： G06K9/00
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method for measuring residual protein in a cellular specimen including obtaining a low magnification image of a candidate object of interest, filtering the candidate object of interest pixels with a low pass filter, morphologically processing the candidate object of interest pixels to identify artifact pixels, identifying the candidate object of interest by eliminating artifact pixels, acquiring a higher magnification image of the subsample for the candidate object of interest, transforming pixels of the higher magnification image in a first color space to a second color space to differentiate higher magnification candidate object of interest pixels from background pixels, identifying an object of interest from the candidate object of interest pixels in the second color space, and determining the optical density of the protein in a cell contained in a subsample, wherein the optical density is indicative of the residual component of a cellular protein.
摘要翻译：一种用于测量细胞样本中残留蛋白质的方法，包括获得感兴趣的候选对象的低倍率图像，利用低通滤波器过滤候选对象像素，在形态上处理候选对象像素以识别伪像，识别通过消除伪影像素来获取所述候选对象，获取用于所述候选对象的子样本的较高放大图像，将第一颜色空间中的较高倍率图像的像素变换为第二颜色空间，以区分感兴趣的较高倍率候选对象从背景像素的像素，从第二颜色空间中的候选对象像素识别感兴趣的对象，以及确定子样本中包含的细胞中的蛋白质的光密度，其中光密度指示残留分量细胞蛋白。

7. 发明授权

US07359536B2 Automated method for image analysis of residual protein 有权
标题翻译：残留蛋白图像分析自动化方法
公开(公告)号：US07359536B2
公开(公告)日：2008-04-15
申请号：US10728698
申请日：2003-12-05
申请人： Presley Hays , Michal L. Peri , Douglas Harrington
发明人： Presley Hays , Michal L. Peri , Douglas Harrington
IPC分类号： G06K9/00
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： An automated method for evaluating the amount of residual protein levels following treatment of cellular specimens. Particular methods include the measurement of maternal neutrophil alkaline phosphatase after treatment with or without urea or heat, measurement of leukocyte acid phosphatase after treatment with or without tartrate, and measurement of leukocyte esterase after treatment with α-naphthol butyrate with or without fluoride.
摘要翻译：一种用于评估细胞标本治疗后残留蛋白质水平的自动化方法。具体方法包括用或不用尿素或加热处理后测量母体嗜中性粒细胞碱性磷酸酶，用或不用酒石酸盐处理后测量白细胞酸性磷酸酶，以及在用或不含氟化物的α-萘酚丁酸酯处理后测定白细胞酯酶。

8. 发明申请

US20110040146A1 Method and Apparatus for Tubal Occlusion 有权
标题翻译：用于管状闭塞的方法和装置
公开(公告)号：US20110040146A1
公开(公告)日：2011-02-17
申请号：US12912087
申请日：2010-10-26
申请人： Douglas Harrington , Victoria E. Carr-Brendel , Brett S. Bownan
发明人： Douglas Harrington , Victoria E. Carr-Brendel , Brett S. Bownan
IPC分类号： A61F6/06 , A61B18/18 , A61B1/00
CPC分类号： A61F6/225 , A61B17/12022 , A61B17/12099 , A61B17/1219 , A61B18/1485 , A61B2018/00559 , A61B2018/126 , A61B2018/162
摘要： Disclosed herein is a device adapted for occluding the ovarian pathway of a female body for sterilization purposes. The device delivers RF energy to wound tissue at a desired location within at least one fallopian tube and implants a porous foam plug adjacent to the wounded tissue at said location. Depending on the plug's pore sizes, vascularized tissue may grow into the plug to prevent or discourage the formation of scar tissue around the plug and/or a vascularized capsule may form around the plug, which limits the patient's foreign body response so that the capsule does not constrict around the plug.
摘要翻译：本文公开了一种用于闭塞雌性体的卵巢途径用于灭菌目的的装置。该装置在至少一个输卵管内的期望位置处向伤口组织递送RF能量，并且在所述位置处植入邻近受伤组织的多孔泡沫塞。取决于塞子的孔径，血管化的组织可以生长到塞子中以防止或阻止栓塞周围的瘢痕组织的形成和/或血栓形成的胶囊可以在塞子周围形成，这限制了患者的异物反应，使得胶囊不会围绕插头收缩。

9. 发明申请

US20060089658A1 Method and apparatus for treating abnormal uterine bleeding 审中-公开
标题翻译：治疗异常子宫出血的方法和装置
公开(公告)号：US20060089658A1
公开(公告)日：2006-04-27
申请号：US10971299
申请日：2004-10-21
申请人： Douglas Harrington
发明人： Douglas Harrington
IPC分类号： A61B17/42
CPC分类号： A61B17/42 , A61B17/12031 , A61B17/12099 , A61B17/12136 , A61B17/12181
摘要： A method and device for creating amenorrhea in women. A porous biomaterial implant is positioned into the ablated uterine cavity of a female patient. Once positioned in the uterine cavity, the porous biomaterial implant expands into its preformed shape or is inflated within the uterine cavity. The ablated uterine tissue then grows within the porous implant. Prior to insertion of the implant, the uterine cavity is prepared by performing endometrial ablation to at least the inferior or lower portion of the uterine cavity. Placement of the porous biomaterial causes the uterine cavity walls to coapt, achieving complete occlusion of the uterine cavity and prevention of endometrial regrowth.
摘要翻译：一种在妇女中产生闭经的方法和装置。将多孔生物材料植入物置于女性患者的消融子宫腔中。一旦定位在子宫腔中，多孔生物材料植入物就会膨胀成其预先形状或在子宫腔内充气。然后，消融的子宫组织在多孔植入物内生长。在插入植入物之前，通过对子宫腔的至少下部或下部进行子宫内膜消融来制备子宫腔。多孔生物材料的放置导致子宫腔壁进行适应，达到完全闭塞子宫腔并防止子宫内膜再生长。

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