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    • 5. 发明申请
    • DRUG-COATED MEDICAL DEVICES FOR DIFFERENTIAL DRUG RELEASE
    • 用于不同药物释放的药物包装医疗器械
    • WO2009099935A2
    • 2009-08-13
    • PCT/US2009/032604
    • 2009-01-30
    • BOSTON SCIENTIFIC SCIMED, INC.
    • SUTERMEISTER, DerekARCAND, BenjaminRIZQ, RaedWENTLAND, AdamRASSAT, Jay
    • A61L31/10A61L31/16
    • A61L31/10A61L31/16A61L2300/61
    • The embodiments described herein relate generally to medical devices that are useful for delivering one or more therapeutic agents to a body tissue of a subject, and methods for making and using such devices. In particular, the embodiments relate to a medical device such as a stent having a sidewall structure comprising a plurality of struts, in which one or more therapeutic agents are released from different surfaces of the struts at different release profiles. More particularly, the embodiments relate to a stent having a sidewall structure comprising a plurality of struts, in which the two side surfaces of each strut are coated with a coating composition that is different from the coating composition used to coat the outer surface and/or inner surface of the strut.
    • 本文所述的实施方案一般涉及可用于将一种或多种治疗剂递送至受试者的身体组织的医疗装置,以及用于制造和使用这些装置的方法。 具体地,实施例涉及医疗装置,例如具有侧壁结构的支架,其包括多个支柱,其中一个或多个治疗剂在不同释放曲线下从支柱的不同表面释放。 更具体地,实施例涉及一种具有侧壁结构的支架,该侧壁结构包括多个支柱,其中每个支柱的两个侧表面涂覆有与用于涂覆外表面的涂料组合物不同的涂料组合物和/或 支柱的内表面。