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1. 发明申请

WO2013126576A1 IMAGING DEVICE AND METHODS OF USING THE SAME 审中-公开
标题翻译：成像装置及其使用方法
公开(公告)号：WO2013126576A1
公开(公告)日：2013-08-29
申请号：PCT/US2013/027143
申请日：2013-02-21
申请人： BOSTON SCIENTIFIC SCIMED, INC. , NAGALE, Sandra
发明人： NAGALE, Sandra
IPC分类号： A61B1/06 , A61B1/07 , A61B5/00
CPC分类号： A61B5/0084 , A61B1/00165 , A61B1/0623 , A61B1/0638 , A61B1/07 , A61B5/0035 , A61B5/0075 , A61B5/6885 , A61B5/6886 , A61B2562/0238
摘要： In one embodiment, a medical device includes a first optical fiber, a second optical fiber, a third optical fiber, and a fourth optical fiber. The first optical fiber is operatively coupled to a first electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second optical fiber is configured to receive electromagnetic radiation from the first electromagnetic radiation source scattered by the bodily tissue. The third optical fiber is operatively coupled to a second electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second electromagnetic radiation source is different than the first electromagnetic radiation source. The fourth optical fiber is configured to receive electromagnetic radiation from the second electromagnetic radiation source scattered by the bodily tissue.
摘要翻译：在一个实施例中，医疗装置包括第一光纤，第二光纤，第三光纤和第四光纤。第一光纤可操作地耦合到第一电磁辐射源并且被配置为将电磁辐射传输到身体组织。第二光纤被配置为接收来自由身体组织散射的第一电磁辐射源的电磁辐射。第三光纤可操作地耦合到第二电磁辐射源，并且被配置为将电磁辐射传输到身体组织。第二电磁辐射源与第一电磁辐射源不同。第四光纤被配置为从由身体组织散射的第二电磁辐射源接收电磁辐射。

2. 发明申请

WO2013052848A1 METHODS FOR DETECTION AND THERMAL TREATMENT OF LOWER URINARY TRACT CONDITIONS 审中-公开
标题翻译：检测和热处理下尿路感染条件的方法
公开(公告)号：WO2013052848A1
公开(公告)日：2013-04-11
申请号：PCT/US2012/059028
申请日：2012-10-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , YOUNG, John, S. , CHENG, Ruth , SHERRY, John , HAGUE, Theresa , BORZELLECA, David , NAGALE, Sandra , FRY, Christopher, H.
发明人： YOUNG, John, S. , CHENG, Ruth , SHERRY, John , HAGUE, Theresa , BORZELLECA, David , NAGALE, Sandra , FRY, Christopher, H.
IPC分类号： A61B5/20
CPC分类号： A61B5/202 , A61B5/6852 , A61B5/6874 , A61B18/02 , A61B18/1492 , A61B18/1815 , A61B18/201 , A61B18/22 , A61B2018/0016 , A61B2018/00166 , A61B2018/00517 , A61B2018/00577 , A61B2018/00791 , A61B2018/046
摘要： The invention is directed to a method for treating a urinary system. The method includes positioning one or more treatment units with respect to an organ wall. The one or more treatment units may be configured to deliver thermal energy. The method further includes delivering energy through the one or more treatment units to heat tissue of the organ wall.
摘要翻译：本发明涉及一种治疗泌尿系统的方法。该方法包括相对于器官壁定位一个或多个处理单元。一个或多个处理单元可以被配置为传递热能。该方法还包括通过一个或多个处理单元输送能量以加热器官壁的组织。

3. 发明申请

WO2017024135A1 SMART DEVICE FOR BLADDER MAPPING 审中-公开
标题翻译：用于刀片映射的SMART设备
公开(公告)号：WO2017024135A1
公开(公告)日：2017-02-09
申请号：PCT/US2016/045555
申请日：2016-08-04
申请人： BOSTON SCIENTIFIC SCIMED, INC. , NAGALE, Sandra , SHOME, Shibaji , HARRAH, Timothy , BODEN, Mark , SHUROS, Allan , CLARK, Bryan , CHIAVETTA, Amedeo , SWANSON, Lynne , WEMER, Dennis
发明人： NAGALE, Sandra , SHOME, Shibaji , HARRAH, Timothy , BODEN, Mark , SHUROS, Allan , CLARK, Bryan , CHIAVETTA, Amedeo , SWANSON, Lynne , WEMER, Dennis
IPC分类号： A61B5/20 , A61B5/00 , A61B5/053 , A61B5/107
CPC分类号： A61B5/202 , A61B1/00045 , A61B1/04 , A61B1/07 , A61B1/307 , A61B5/04882 , A61B5/0538 , A61B5/1076 , A61B5/20 , A61B5/205 , A61B5/4836 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6874 , A61B5/6885 , A61B5/74 , A61B18/1492 , A61B2018/0022 , A61B2018/00267 , A61B2018/00517 , A61B2018/00577 , A61B2562/166 , A61N1/36007
摘要： Systems, devices and methods for the treatment of bladder conditions using bladder visualization without the need for optical elements and for subsequent direct electrical pacing are provided. The systems, devices and methods generally apply pacing stimulus directly to the bladder wall, from one or more of the inner and outer bladder surfaces.
摘要翻译：提供了使用膀胱可视化治疗膀胱状况的系统，装置和方法，而不需要光学元件和随后的直接起搏。系统，装置和方法通常将起搏刺激直接从膀胱壁的一个或多个施加到膀胱壁上。

4. 发明申请

WO2017024056A1 SYSTEMS AND METHODS FOR MAPPING AND ABLATION IN THE BLADDER 审中-公开
标题翻译：用于在刀片中绘制和排列的系统和方法
公开(公告)号：WO2017024056A1
公开(公告)日：2017-02-09
申请号：PCT/US2016/045395
申请日：2016-08-03
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： BODEN, Mark , NAGALE, Sandra , MENDELSON, Yitzhak , GAUDETTE, Glenn , CAVALLARO, Deanna , RICHARDSON, Tristan , HICKEY, Tyler , SHURAIM, Rami , GOKSUN, Dervis
IPC分类号： A61B18/14 , A61B18/00 , A61B17/00
CPC分类号： A61B18/1492 , A61B2017/00022 , A61B2017/00053 , A61B2018/00166 , A61B2018/0022 , A61B2018/00238 , A61B2018/0025 , A61B2018/00261 , A61B2018/00517 , A61B2018/00523 , A61B2018/00577 , A61B2018/00654 , A61B2018/00708 , A61B2018/00839 , A61B2018/144 , A61B2018/1467
摘要： The present disclosure relates to the field of tissue mapping and ablation. Specifically, the present disclosure relates to expandable medical devices for identifying and treating local anatomical abnormalities within a body lumen. More specifically, the present disclosure relates to systems and methods of focal treatment for overactive bladders.
摘要翻译：本公开涉及组织测绘和消融领域。具体地，本公开涉及用于识别和治疗体腔内局部解剖异常的可扩张医疗装置。更具体地，本公开涉及用于过度活动囊的局部治疗的系统和方法。

5. 发明申请

WO2016154371A1 METHODS AND DEVICES FOR IDENTIFYING TREATMENT SITES 审中-公开
标题翻译：识别治疗场所的方法和设备
公开(公告)号：WO2016154371A1
公开(公告)日：2016-09-29
申请号：PCT/US2016/023881
申请日：2016-03-24
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： NAGALE, Sandra , CLARK, Bryan , HE, Ding, Sheng , SWANSON, Lynne , WERNER, Dennis , HARRAH, Timothy
IPC分类号： A61B5/0488 , A61B5/00 , A61B18/14 , A61B18/24 , A61B5/20 , A61N1/36 , A61B18/00 , A61B18/02 , A61B18/18 , A61N7/00
CPC分类号： A61B5/04882 , A61B5/0492 , A61B5/0538 , A61B5/202 , A61B5/4836 , A61B5/6858 , A61B18/1485 , A61B18/1492 , A61B18/24 , A61B2017/00039 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00285 , A61B2018/00517 , A61B2018/00559 , A61B2018/00577 , A61B2018/00601 , A61B2018/00613 , A61B2018/00642 , A61B2018/00654 , A61B2018/00666 , A61B2018/00732 , A61B2018/00791 , A61B2018/00827 , A61B2018/00839 , A61B2018/00875 , A61B2018/0212 , A61B2018/1425 , A61B2018/143 , A61B2018/1861 , A61N1/327 , A61N1/36007 , A61N7/00 , A61N7/022 , A61N2007/0043 , G06T7/0012
摘要： Methods and devices for identifying a treatment site are disclosed. The methods may include engaging a plurality electrodes with plurality of locations on or adjacent an interior wall of a patient. The methods may also include generating a pacing stimulus through a first pair of the plurality of electrodes and measuring a resulting electrical activity. The methods may also include identifying at least one site for treatment based on the resulting electrical activity. The devices may include elements configured to perform these methods. The device comprises a plurality of electrodes; a memory device configured to store an instruction for evaluating electrical activity; and a processor configured to: access the instruction from the memory; direct, with the instruction, an electrical energy source to generate a pacing stimulus through a first pair of the plurality of electrodes; measure, with the instruction, a resulting electrical activity at one or more of the plurality of electrodes; and identify, with the instruction, at least one treatment site based the resulting electrical activity. The processor is further configured to initiate, with the instruction, a therapy to the least one treatment site, such as a radio frequency energy, an ultrasound energy, a laser energy, a cryoablation, a microwave ablation, a Botox injection, a neurolytic agent, an optical energy, an irreversible electroporation, and a hydrogel injection.
摘要翻译：公开了用于识别治疗部位的方法和装置。所述方法可以包括使多个电极与患者的内壁上或附近的多个位置接合。所述方法还可以包括通过第一对多个电极产生起搏刺激并测量所得到的电活动。所述方法还可以包括基于所得的电活动识别至少一个用于治疗的部位。设备可以包括被配置为执行这些方法的元件。该装置包括多个电极; 存储装置，被配置为存储用于评估电活动的指令; 以及处理器，被配置为：从所述存储器访问所述指令; 通过该指令直接指示电能源，以通过第一对多个电极产生起搏刺激; 通过说明来测量在多个电极中的一个或多个上产生的电活动; 并根据指示确定至少一个治疗部位，以形成所产生的电活动。处理器还被配置为通过该指令来启动对至少一个治疗部位的治疗，例如射频能量，超声能量，激光能量，冷冻消融，微波消融，肉毒杆菌毒素注射，神经溶解剂，光能，不可逆电穿孔和水凝胶注射。

6. 发明申请

WO2013052852A1 METHODS AND SYSTEMS FOR DETECTION AND THERMAL TREATMENT OF LOWER URINARY TRACT CONDITIONS 审中-公开
标题翻译：用于检测和热处理下尿路症状的方法和系统
公开(公告)号：WO2013052852A1
公开(公告)日：2013-04-11
申请号：PCT/US2012/059033
申请日：2012-10-05
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： NAGALE, Sandra , CHENG, Ruth , SHERRY, John , BORZELLECA, David
IPC分类号： A61B5/20
CPC分类号： A61B5/6874 , A61B5/202 , A61B5/6852 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B2017/00057 , A61B2017/00075 , A61B2018/00005 , A61B2018/00047 , A61B2018/0016 , A61B2018/00166 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00517 , A61B2018/00642 , A61B2018/00839 , A61B2018/0212 , A61F2/0063 , A61N7/00
摘要： The invention relates generally to systems and methods for detecting and/or treating lower urinary tract conditions. One embodiment of the invention is directed to a medical device. The medical device (10) includes an elongate member (12) having a proximal end (18) and a distal end (20) and an end effector assembly (16) that extends distally from the distal end of the elongate member. The end effector assembly (16) includes a plurality of end effector units (22). Each end effector unit has a sensing element for detecting a location of abnormal organ function and a treatment element for treating the location of abnormal organ function.
摘要翻译：本发明一般涉及用于检测和/或治疗下尿路状况的系统和方法。本发明的一个实施例涉及医疗装置。医疗装置（10）包括具有近端（18）和远端（20）的细长构件（12）和从细长构件的远端向远端延伸的端部执行器组件（16）。末端执行器组件（16）包括多个端部执行器单元（22）。每个末端执行器单元具有用于检测异常器官功能的位置的感测元件和用于治疗异常器官功能的位置的治疗元件。

7. 发明申请

WO2017079459A2 MEDICAL DEVICE AND RELATED METHODS 审中-公开
标题翻译：医疗装置和相关方法
公开(公告)号：WO2017079459A2
公开(公告)日：2017-05-11
申请号：PCT/US2016/060366
申请日：2016-11-03
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： HE, Ding Sheng , NAGALE, Sandra , SHUROS, Allan Charles , GIBSON, Charles , SWANSON, Lynne , WERNER, Dennis , HARRAH, Timothy Paul , BODEN, Mark , PETERSON, Michael Charles , DIAMOND, Steven , CHIAVETTA, Amedeo
IPC分类号： A61B18/14
CPC分类号： A61N1/36007 , A61B5/04882 , A61B5/04884 , A61B5/0492 , A61B5/05 , A61B5/0536 , A61B5/0538 , A61B5/202 , A61B5/4836 , A61B17/320068 , A61B18/02 , A61B18/1492 , A61B2018/00029 , A61B2018/0016 , A61B2018/00267 , A61B2018/00517 , A61B2018/00577 , A61B2018/00839 , A61B2018/00875 , A61B2018/1465 , A61B2018/1475 , A61N1/025 , A61N1/303
摘要： In one aspect, the present disclosure is directed to a method for identifying a site with a patient for treatment. The method may include engaging a plurality electrodes with an interior wall of the patient at a plurality of locations. The method may also generating a virtual map of a plurality of electrodes, wherein each of the plurality of electrodes is displayed with a first indicia. The method may also include displaying each of the plurality of electrodes engaged with the interior wall with a second indicia, measuring electrical activity, identifying at least one site for treatment based on the measured resulting electrical activity, and displaying each of the plurality of electrodes identified for treatment with a third indicia.
摘要翻译：在一个方面，本公开涉及一种用于识别患者进行治疗的部位的方法。该方法可以包括在多个位置处使多个电极与患者的内壁接合。该方法还可以生成多个电极的虚拟图，其中多个电极中的每一个电极都显示有第一标记。该方法还可以包括用第二标记显示与内壁接合的多个电极中的每一个，测量电活动，基于测量的所得电活动识别用于治疗的至少一个部位，以及显示识别的多个电极中的每一个用第三个标记进行治疗。

8. 发明申请

WO2017024057A1 EXPANDABLE BALLOON MAPPING AND ABLATION DEVICE 审中-公开
标题翻译：可膨胀的气球映射和排除装置
公开(公告)号：WO2017024057A1
公开(公告)日：2017-02-09
申请号：PCT/US2016/045396
申请日：2016-08-03
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： NAGALE, Sandra , BODEN, Mark , CLARK, Bryan , SHOME, Shibaji , CHIAVETTA, Amedeo
IPC分类号： A61B18/14 , A61B18/00 , A61B17/00
CPC分类号： A61B18/1485 , A61B5/04882 , A61B5/202 , A61B5/6853 , A61B18/1492 , A61B2017/00022 , A61B2017/00044 , A61B2017/00053 , A61B2018/00178 , A61B2018/0022 , A61B2018/00267 , A61B2018/00517 , A61B2018/00577 , A61B2018/00642 , A61B2018/00839 , A61B2018/1467 , A61B2018/1475 , A61N1/0514 , A61N1/36007
摘要： The present disclosure relates to the field of tissue mapping and ablation. Specifically, the present disclosure relates to expandable medical devices for identifying and treating local anatomical abnormalities within a body lumen. More specifically, the present disclosure relates to systems and methods of focal treatment for overactive bladders.
摘要翻译：本公开涉及组织测绘和消融领域。具体地，本公开涉及用于识别和治疗体腔内局部解剖异常的可扩张医疗装置。更具体地，本公开涉及用于过度活动囊的局部治疗的系统和方法。

9. 发明申请

WO2013119830A1 SURGICAL SCAFFOLDS 审中-公开
标题翻译：外科手术
公开(公告)号：WO2013119830A1
公开(公告)日：2013-08-15
申请号：PCT/US2013/025171
申请日：2013-02-07
申请人： BOSTON SCIENTIFIC SCIMED, INC. , NAGALE, Sandra , BODEN, Mark W.
发明人： NAGALE, Sandra , BODEN, Mark W.
IPC分类号： A61L27/50 , A61L31/14 , A61F2/00
CPC分类号： A61F2/0063 , A61F2/0045 , A61F2230/006 , A61L31/06 , A61L31/146 , A61L31/16 , A61L2300/43 , A61L2430/30 , A61L2430/34 , F04C2270/041 , C08L75/04
摘要： According to an aspect of the present invention, surgical scaffolds for soft tissue repair are provided. The surgical scaffolds comprise a sheet of a material within which through-holes are formed. Further aspects of the invention, among others, pertain to methods of using such surgical scaffolds and to kits containing such surgical scaffolds.
摘要翻译：根据本发明的一个方面，提供了用于软组织修复的手术支架。手术支架包括形成通孔的材料片。本发明的其它方面以及其它方面涉及使用这种手术支架的方法和含有这种手术支架的试剂盒。

10. 发明申请

WO2019103870A1 SYSTEM FOR MONITORING STATE OF INFLAMMATORY BOWEL DISEASE 审中-公开
公开(公告)号：WO2019103870A1
公开(公告)日：2019-05-31
申请号：PCT/US2018/060622
申请日：2018-11-13
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： CLARK, Bryan Allen , ANNONI, Elizabeth M. , NAGALE, Sandra , STAHMANN, Jeffrey E. , SRIVASTAVA, Kyle Harish , BODEN, Mark W. , PHELAN, Martin , DUVAL, George Wilfred
IPC分类号： A61B5/00 , A61B5/021 , A61B5/0245 , A61B5/08
摘要： An example of a system for monitoring and treating a medical condition of a patient may include signal inputs to receive patient condition signals indicative of a state of inflammatory bowel disease (IBD), a signal processing circuit configured to process the patient condition signals and generate patient condition parameters indicative of the state of IBD using the processed patient condition signals, and a medical condition analyzer configured to analyze the patient condition parameters and determine the medical condition including the state of IBD using an outcome of the analysis. The patient condition parameters may include one or more physiological marker parameters each representative of a physiological marker of IBD and one or more quality of life parameters each being measure of quality of life of the patient.

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