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1. 发明授权

US07270634B2 Guidance of invasive medical devices by high resolution three dimensional ultrasonic imaging 有权
标题翻译：通过高分辨率三维超声成像对侵入性医疗器械的指导
公开(公告)号：US07270634B2
公开(公告)日：2007-09-18
申请号：US10780443
申请日：2004-02-17
申请人： Steven Scampini , Michael Peszynski , Ivan Salgo , Bernard Savord
发明人： Steven Scampini , Michael Peszynski , Ivan Salgo , Bernard Savord
IPC分类号： A61B8/00
CPC分类号： G01S7/52074 , A61B5/061 , A61B5/062 , A61B5/063 , A61B5/065 , A61B5/068 , A61B8/00 , A61B8/0833 , A61B8/0841 , A61B8/483 , G01S7/52073 , G01S7/52085 , G01S7/52095 , G01S15/8993 , Y10S128/916
摘要： A three dimensional ultrasonic diagnostic imaging system is operated to guide or observe the operation of an invasive medical device (30) in three dimensions. The appearance of the invasive device (30) in the three dimensional ultrasonic image is enhanced to be more readily observable by a clinician. The enhancement is produced by transmitting a greater ultrasonic beam density in a subvolumetric region including the invasive device (30) than in the surrounding portion of the volumetric region (120). The beam density may be uniformly high in the subvolumetric region and uniformly low in the surrounding region, or may taper from a relatively high beam density around the invasive device (30) to a minimum beam density at distances removed from the invasive device (30).
摘要翻译：操作三维超声诊断成像系统以引导或观察三维的侵入性医疗装置（30）的操作。三维超声图像中的侵入性装置（30）的外观被增强以便由临床医生更容易观察到。通过在包括侵入性装置（30）的子体积区域中比在体积区域（120）的周围部分中传输更大的超声波束密度来产生增强。光束密度可以在子体积区域中均匀地高，并且在周围区域中均匀地低，或者可以从入侵设备（30）周围的相对较高的光束密度逐渐减小到从侵入性设备（30）移除的距离处的最小光束密度，。

2. 发明授权

US07796789B2 Guidance of invasive medical devices by three dimensional ultrasonic imaging 有权
标题翻译：通过三维超声成像对侵入性医疗器械的指导
公开(公告)号：US07796789B2
公开(公告)日：2010-09-14
申请号：US10550214
申请日：2004-03-04
申请人： Ivan Salgo , Bernard Savord , Steven Scampini , Michael Peszynski
发明人： Ivan Salgo , Bernard Savord , Steven Scampini , Michael Peszynski
IPC分类号： G06K9/00 , A61B8/00
CPC分类号： A61B8/0841 , A61B8/0833 , A61B8/4245 , A61B8/4263 , A61B8/463 , A61B8/483 , A61B34/20 , A61B90/36 , A61B2017/00703 , A61B2034/105 , A61B2034/2051 , A61B2090/364 , A61B2090/367 , A61B2090/378
摘要： A three dimensional ultrasonic diagnostic imaging system is operated to guide or observe the operation of an invasive medical device (30) in three dimensions. An interventional system (20) is used to operate the invasive medical device (30) and produces spatially-based information relating to the activity of the invasive medical device (30). The spatially-based information from the interventional system (20) is merged into the three dimensional ultrasonic image data to produce a live three dimensional image of the invasive medical device (30) or its activity. In one embodiment the locations where the activity of the invasive medical device (30) is performed is recorded and displayed in the three dimensional ultrasonic image. The three dimensional ultrasonic image may be shown as an anatomical volume rendered image or as a wire frame model (130) of the anatomy. In another embodiment an integrated three dimensional ultrasonic imaging and invasive device system is described.
摘要翻译：操作三维超声诊断成像系统以引导或观察三维的侵入性医疗装置（30）的操作。介入系统（20）用于操作侵入性医疗装置（30）并产生与侵入性医疗装置（30）的活动有关的基于空间的信息。来自介入系统（20）的基于空间的信息被合并到三维超声图像数据中以产生侵入性医疗装置（30）的活三维图像或其活动。在一个实施例中，进行侵入性医疗装置（30）的活动的位置被记录并显示在三维超声图像中。三维超声图像可以示出为解剖体积渲染图像或者作为解剖结构的线框架模型（130）。在另一个实施例中，描述了一体的三维超声成像和侵入性装置系统。

3. 发明申请

US20060193504A1 Guidance of invasive medical devices by three dimensional ultrasonic imaging 有权
标题翻译：通过三维超声成像对侵入性医疗器械的指导
公开(公告)号：US20060193504A1
公开(公告)日：2006-08-31
申请号：US10550214
申请日：2004-03-04
申请人： Ivan Salgo , Bernard Savord , Steven Scampini , Michael Peszynski
发明人： Ivan Salgo , Bernard Savord , Steven Scampini , Michael Peszynski
IPC分类号： G06K9/00
CPC分类号： A61B8/0841 , A61B8/0833 , A61B8/4245 , A61B8/4263 , A61B8/463 , A61B8/483 , A61B34/20 , A61B90/36 , A61B2017/00703 , A61B2034/105 , A61B2034/2051 , A61B2090/364 , A61B2090/367 , A61B2090/378
摘要： A three dimensional ultrasonic diagnostic imaging system is operated to guide or observe the operation of an invasive medical device (30) in three dimensions. An interventional system (20) is used to operate the invasive medical device (30) and produces spatially-based information relating to the activity of the invasive medical device (30). The spatially-based information from the interventional system (20) is merged into the three dimensional ultrasonic image data to produce a live three dimensional image of the invasive medical device (30) or its activity. In one embodiment the locations where the activity of the invasive medical device (30) is performed is recorded and displayed in the three dimensional ultrasonic image. The three dimensional ultrasonic image may be shown as an anatomical volume rendered image or as a wire frame model (130) of the anatomy. In another embodiment an integrated three dimensional ultrasonic imaging and invasive device system is described.
摘要翻译：操作三维超声诊断成像系统以引导或观察三维的侵入性医疗装置（30）的操作。介入系统（20）用于操作侵入性医疗装置（30）并产生与侵入性医疗装置（30）的活动有关的基于空间的信息。来自介入系统（20）的基于空间的信息被合并到三维超声图像数据中以产生侵入性医疗装置（30）的活三维图像或其活动。在一个实施例中，进行侵入性医疗装置（30）的活动的位置被记录并显示在三维超声图像中。三维超声图像可以示出为解剖体积渲染图像或者作为解剖结构的线框架模型（130）。在另一个实施例中，描述了一体的三维超声成像和侵入性装置系统。

4. 发明申请

US20060182320A1 Guidance of invasive medical devices by wide view three dimensional ultrasonic imaging 有权
标题翻译：通过广视三维超声成像技术对侵入性医疗器械的指导
公开(公告)号：US20060182320A1
公开(公告)日：2006-08-17
申请号：US10550210
申请日：2004-03-04
申请人： Michael Peszynski , Ivan Salgo , Bernard Savord , Steven Scampini
发明人： Michael Peszynski , Ivan Salgo , Bernard Savord , Steven Scampini
IPC分类号： G06K9/00
CPC分类号： A61B8/483 , A61B8/0833 , A61B8/0841 , A61B8/0883 , A61B8/463 , A61B34/20 , A61B2034/105 , A61B2034/2051 , A61B2090/378 , A61B2090/3782 , G01S7/52073 , G01S7/52074 , G01S7/52085 , G01S7/52095 , G01S15/8993
摘要： A three dimensional ultrasonic diagnostic imaging system is operated to guide or observe the operation of an invasive medical device (30) in three dimensions. The invasive medical device (30) is shown in a detailed ultrasonic image and the balance of the volumetric region (120) in which the device is located is shown in a wide field of view. The detailed and wide fields of view may be displayed separately or overlapping in spatial alignment on an image display (18). The wide field of view may be shown in two or three dimensions. A quantified display may be shown together with the wide and detailed anatomical displays. The detailed view may also be shown in an enlarged or zoomed format.
摘要翻译：操作三维超声诊断成像系统以引导或观察三维的侵入性医疗装置（30）的操作。该侵入性医疗装置（30）以详细的超声波图像示出，并且在宽视场中示出了装置所在的体积区域（120）的平衡。详细和广泛的视野可以在图像显示器（18）上分开显示或以空间对准重叠。宽视野可以以二维或三维来显示。量化显示可以与广泛和详细的解剖显示一起显示。详细视图也可以放大或缩小的格式显示。

5. 发明授权

US07529393B2 Guidance of invasive medical devices by wide view three dimensional ultrasonic imaging 有权
标题翻译：通过广视三维超声成像技术对侵入性医疗器械的指导
公开(公告)号：US07529393B2
公开(公告)日：2009-05-05
申请号：US10550210
申请日：2004-03-04
申请人： Michael Peszynski , Ivan Salgo , Bernard Savord , Steven Scampini
发明人： Michael Peszynski , Ivan Salgo , Bernard Savord , Steven Scampini
IPC分类号： G06K9/00
CPC分类号： A61B8/483 , A61B8/0833 , A61B8/0841 , A61B8/0883 , A61B8/463 , A61B34/20 , A61B2034/105 , A61B2034/2051 , A61B2090/378 , A61B2090/3782 , G01S7/52073 , G01S7/52074 , G01S7/52085 , G01S7/52095 , G01S15/8993
摘要： A three dimensional ultrasonic diagnostic imaging system is operated to guide or observe the operation of an invasive medical device (30) in three dimensions. The invasive medical device (30) is shown in a detailed ultrasonic image and the balance of the volumetric region (120) in which the device is located is shown in a wide field of view. The detailed and wide fields of view may be displayed separately or overlapping in spatial alignment on an image display (18). The wide field of view may be shown in two or three dimensions. A quantified display may be shown together with the wide and detailed anatomical displays. The detailed view may also be shown in an enlarged or zoomed format.
摘要翻译：操作三维超声诊断成像系统以引导或观察三维的侵入性医疗装置（30）的操作。该侵入性医疗装置（30）以详细的超声波图像示出，并且在宽视场中示出了装置所在的体积区域（120）的平衡。详细和广泛的视野可以在图像显示器（18）上分开显示或以空间对准重叠。宽视野可以以二维或三维来显示。量化显示可以与广泛和详细的解剖显示一起显示。详细视图也可以放大或缩小的格式显示。

6. 发明申请

US20060270934A1 Guidance of invasive medical devices with combined three dimensional ultrasonic imaging system 审中-公开
标题翻译：具有组合三维超声成像系统的侵入性医疗装置的指导
公开(公告)号：US20060270934A1
公开(公告)日：2006-11-30
申请号：US10550212
申请日：2004-03-04
申请人： Bernard Savord , Steven Scampini , Michael Peszynski , Ivan Salgo
发明人： Bernard Savord , Steven Scampini , Michael Peszynski , Ivan Salgo
IPC分类号： A61B8/00
CPC分类号： G01S7/52074 , A61B8/0833 , A61B8/4254 , A61B8/483 , G01S7/52068 , G01S15/8993
摘要： A composite three dimensional ultrasound image containing position or image information of an invasive medical device (30) is provided. The three dimensional ultrasound image data can be combined with position or image information of the invasive medical device (30) either prior to or subsequent to volume rendering. the three dimensional ultrasound image data and the interventional system data are oriented and sealed to a common frame of reference and then combined. The volume rendering can be performed either on the ultrasound system (12), on the interventional system (20), or separately on both before combining.
摘要翻译：提供了包含侵入性医疗装置（30）的位置或图像信息的复合三维超声图像。三维超声图像数据可以在体绘制之前或之后与侵入性医疗装置（30）的位置或图像信息组合。将三维超声图像数据和介入系统数据定向并密封到公共参考系，然后组合。体积渲染可以在超声系统（12），介入系统（20）上执行，也可以在组合之前分别执行。

7. 发明申请

US20070173737A1 Cell collection device 有权
标题翻译：细胞收集装置
公开(公告)号：US20070173737A1
公开(公告)日：2007-07-26
申请号：US11725846
申请日：2007-03-20
申请人： Steven Scampini
发明人： Steven Scampini
IPC分类号： A61B10/00
CPC分类号： A61B10/0045 , A61B10/0291 , A61B2010/0074
摘要： This invention relates generally to medical devices, and more particularly, an apparatus and method for collecting cells or tissue samples from the cervix of a patient for medical testing.
摘要翻译：本发明一般涉及医疗装置，更具体地说，涉及用于从用于医学测试的患者子宫颈收集细胞或组织样本的装置和方法。

8. 发明授权

US08137642B2 Method and apparatus for calibrating filters during specimen collection 有权
标题翻译：标本采集过程中校准过滤器的方法和装置
公开(公告)号：US08137642B2
公开(公告)日：2012-03-20
申请号：US12482731
申请日：2009-06-11
申请人： Timothy Hutchins , Steven Scampini , Eric Baur
发明人： Timothy Hutchins , Steven Scampini , Eric Baur
IPC分类号： G01D18/00
CPC分类号： G01N1/36
摘要： A bubble point of a combination of a filter and a liquid is calibrated by applying an initial back pressure through the filter toward the liquid; taking a first plurality of measurements of the level of the liquid in the container; calculating a first variance of the first plurality of measurements; and comparing the first calculated variance with a known threshold variance. Then a second plurality of measurements of the level of the liquid in the container is taken; a second variance of the second plurality of measurements is calculated; and the second calculated variance is compared with a known threshold variance. The above described steps are repeated at incrementally increased back pressures until the first and second calculated variances are each greater than or equal to the known threshold variance, which is about 0.01. The bubble point is determined to be the back pressure at that point. If the determined bubble point is less than or equal to the known threshold bubble point, which is about 0.8 pounds per square inch, the filter is identified as unsuitable for use in cell block formation.
摘要翻译：过滤器和液体的组合的起泡点通过将初始的背压通过过滤器朝向液体进行校准; 对容器中液体的水平进行第一次多次测量; 计算所述第一多个测量的第一方差; 以及将第一计算的方差与已知的阈值方差进行比较。然后取出容器中的液体水平的第二多个测量值; 计算第二多个测量的第二方差; 并将第二计算方差与已知的阈值方差进行比较。上述步骤以逐渐增加的背压重复，直到第一和第二计算的方差各自大于或等于已知阈值方差，其为约0.01。泡点确定为此时的背压。如果确定的气泡点小于或等于已知的阈值气泡点（约0.8磅/平方英寸），则过滤器被识别为不适合用于细胞块形成。

9. 发明申请

US20070142746A1 Cell collection device 审中-公开
公开(公告)号：US20070142746A1
公开(公告)日：2007-06-21
申请号：US11314754
申请日：2005-12-21
申请人： Steven Scampini
发明人： Steven Scampini
IPC分类号： A61B10/00
CPC分类号： A61B10/0045 , A61B10/0291 , A61B2010/0074
摘要： This invention relates generally to medical devices, and more particularly, an apparatus and method for collecting cells or tissue samples from the cervix of a patient for medical testing.

10. 发明申请

US20070133085A1 Microscope control device 审中-公开
标题翻译：显微镜控制装置
公开(公告)号：US20070133085A1
公开(公告)日：2007-06-14
申请号：US11298953
申请日：2005-12-09
申请人： Steven Scampini
发明人： Steven Scampini
IPC分类号： G02B21/00
CPC分类号： G02B21/24
摘要： A microscope control device comprises a coarse focus control, a manual navigation control, and a fine focus control. The microscope control device also includes a clutch configured to alternatively activate one of the coarse focus control and manual navigation control. The fine focus control, coarse focus control, manual navigation control, and clutch are configured and arranged for manual manipulation by a single hand of an operator without changing a general position of the hand.
摘要翻译：显微镜控制装置包括粗焦控制，手动导航控制和精细对焦控制。显微镜控制装置还包括配置成交替地激活粗焦控制和手动导航控制之一的离合器。精细对焦控制，粗焦点控制，手动导航控制和离合器被配置和布置成用于操作者的单手的手动操作而不改变手的一般位置。

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