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1. 发明申请

WO2005063154A9 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：混合眼动跟踪系统及相关方法
公开(公告)号：WO2005063154A9
公开(公告)日：2005-09-01
申请号：PCT/US2004043130
申请日：2004-12-23
申请人： ALCON REFRACTIVE HORIZONS INC , GRAY GARY , CAMPIN JOHN A , BOTT STEVEN E , GIBBS DAVID MICHAEL , PETTIT GEORGE H
发明人： GRAY GARY , CAMPIN JOHN A , BOTT STEVEN E , GIBBS DAVID MICHAEL , PETTIT GEORGE H
IPC分类号： A61B18/20 , A61F9/008 , A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system and method for tracking ocular changes during a surgical procedure include directing an eye-safe optical beam toward an undilated, unparalyzed eye. A reflected optical beam is detected, and measurements are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency, and from them is calculated a change in the at least one geometric parameter. The calculated change is used to dynamically adjust the directing of laser beam shots during the surgery.
摘要翻译：用于在外科手术过程中跟踪眼睛变化的系统和方法包括将眼睛安全的光束引向未被剥离的未分析的眼睛。检测反射光束，并且基于预定频率的眼睛的至少一个几何参数的反射光束中包含的数据进行测量，并且根据它们计算至少一个几何参数的变化。计算出的变化用于在手术过程中动态调整激光束拍摄的指导。

2. 发明申请

WO2005063154A3 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：混合眼动跟踪系统及相关方法
公开(公告)号：WO2005063154A3
公开(公告)日：2005-11-24
申请号：PCT/US2004043130
申请日：2004-12-23
申请人： ALCON REFRACTIVE HORIZONS INC , GRAY GARY , CAMPIN JOHN A , BOTT STEVEN E , GIBBS DAVID MICHAEL , PETTIT GEORGE H
发明人： GRAY GARY , CAMPIN JOHN A , BOTT STEVEN E , GIBBS DAVID MICHAEL , PETTIT GEORGE H
IPC分类号： A61B18/20 , A61F9/008 , A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system (10) and method for tracking ocular changes (12, 13) during a surgical procedure include directing an eye-safe optical beam (21) toward an undilated, unparalyzed eye (90). A reflected optical beam (23) is detected (22), and measurements (17) are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency (105), and from them is calculated a change in the at least one geometric parameter (106). The calculated change is used to dynamically adjust the directing of laser beam shots (14) during the surgery.
摘要翻译：用于在外科手术过程中跟踪眼睛变化（12,13）的系统（10）和方法包括将眼睛安全的光束（21）引向朝向未被剥离的未分析的眼睛（90）。检测反射光束（23），并且基于预定频率（105）的眼睛的至少一个几何参数的反射光束中包含的数据执行测量（17），并且从它们是计算所述至少一个几何参数（106）中的变化。计算出的变化用于在手术过程中动态调整激光束射击（14）的引导。

3. 发明申请

WO2008131321A9 ADAPTIVE WAVEFRONT MODULATION SYSTEM AND METHOD FOR REFRACTIVE LASER SURGERY 审中-公开
标题翻译：自适应波前调节系统及其激光激光手术方法
公开(公告)号：WO2008131321A9
公开(公告)日：2010-11-04
申请号：PCT/US2008060976
申请日：2008-04-21
申请人： ALCON REFRACTIVE HORIZONS INC , PETTIT GEORGE H , CAMPIN JOHN A
发明人： PETTIT GEORGE H , CAMPIN JOHN A
IPC分类号： A61B3/103 , A61F9/01
CPC分类号： A61B3/1015 , A61B3/1035 , A61B3/107 , A61F9/008 , A61F9/00806 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088
摘要： A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.
摘要翻译：用于提高激光消融角膜处理的处方精度的方法包括接收包括从患者眼睛的多个像差计测量获得的Hartmann-Shack图像数据的一组原始数据的步骤。 Hartmann-Shack数据可以包括例如每个测量的点图案图像。还接收从多个像差计测量的原始数据集合计算出的一组重建波阵面数据。比较原始数据集合和重建波阵面数据集中的选定分量上的数据。如果所选择的分量数据在原始数据和重构的波前数据之间的预定量不同，则可以在进行激光烧蚀之前进一步操纵原始数据。此外，这些数据从考虑中被删除，以纳入治疗结果数据库。

4. 发明申请

WO2007016132A3 OPHTHALMIC DEVICE LATERAL POSITIONING SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：眼科装置横向定位系统及相关方法
公开(公告)号：WO2007016132A3
公开(公告)日：2007-03-22
申请号：PCT/US2006028936
申请日：2006-07-26
申请人： ALCON REFRACTIVE HORIZONS INC , CAMPIN JOHN A , BOWES JOHN J
发明人： CAMPIN JOHN A , BOWES JOHN J
IPC分类号： A61B3/15 , A61F9/01
CPC分类号： A61F9/008 , A61B3/14 , A61B3/145 , A61B3/152 , A61F9/007 , A61F2009/00872
摘要： A system and method for determining a lateral position of an eye relative to an ophthalmic device are disclosed. One embodiment of the method includes receiving data comprising an image of a surface of an eye. An edge feature in the image is located, wherein the edge feature is in a known relationship to a pupil of the eye. The image is mapped from the edge feature to laterally define the pupil, and a center of the pupil is determined using the pupil definition. The pupil center comprises a location from which to achieve a preferred lateral eye position relative to an ophthalmic device. An embodiment of the system of this invention can include a processor and a software package executable by the processor, the software package adapted to cause the processor to carry out the method steps.
摘要翻译：公开了一种用于确定眼睛相对于眼科装置的侧向位置的系统和方法。该方法的一个实施例包括接收包括眼睛表面的图像的数据。定位图像中的边缘特征，其中边缘特征与眼睛的瞳孔处于已知关系。从边缘特征映射图像以横向定义瞳孔，并使用瞳孔定义确定瞳孔的中心。瞳孔中心包括相对于眼科装置实现优选的侧眼位置的位置。本发明的系统的实施例可以包括处理器和可由处理器执行的软件包，该软件包适于使处理器执行方法步骤。

5. 发明申请

WO2007079076A3 DETERMINING OPTIMAL POSITIONING OF OPHTHALMIC DEVICES BY USE OF IMAGE PROCESSING AND AUTOFOCUSING TECHNIQUES 审中-公开
标题翻译：通过图像处理和自动绘图技术确定眼科装置的最佳定位
公开(公告)号：WO2007079076A3
公开(公告)日：2007-08-30
申请号：PCT/US2006049264
申请日：2006-12-21
申请人： ALCON REFRACTIVE HORIZONS INC , CAMPIN JOHN A , BOWES JOHN J
发明人： CAMPIN JOHN A , BOWES JOHN J
IPC分类号： A61F9/01 , A61B3/10
CPC分类号： A61F9/00802 , A61B3/0075 , A61B3/0083 , A61B3/10 , A61B3/145 , A61F2009/00872 , G06T7/571 , G06T2207/30041
摘要： A system (200) or method of positioning an ophthalmic device relative to an eye is provided. The method first obtains a series of images of an eye. In these series of images, the distance between the ophthalmic device and the eye is varied while the region of the eye image remains substantially the same. It is possible then to process these images to determine the high frequency content associated with each image. By comparing the high frequency content associated with each image, it is possible to determine which image has the largest amount of high frequency content. The high frequency content is maximized when the image is the sharpest. An optimally focused image will have the largest amount of high frequency content . By examining the high frequency content associate with the series of images is impossible to adjust the relative position and distance between the eye and the ophthalmic device to the distance associated with the image having the largest amount of high frequency content (i.e., optimally focused) .
摘要翻译：提供了一种相对于眼睛定位眼科装置的系统（200）或方法。该方法首先获得一系列的眼睛图像。在这些系列图像中，眼睛装置与眼睛之间的距离是变化的，而眼睛图像的区域保持基本相同。然后可以处理这些图像以确定与每个图像相关联的高频内容。通过比较与每个图像相关联的高频内容，可以确定哪个图像具有最大量的高频内容。当图像最清晰时，高频内容最大化。最佳聚焦图像将具有最大量的高频内容。通过检查与该系列图像相关联的高频内容不可能将眼睛和眼科装置之间的相对位置和距离调整为与具有最大量的高频内容（即，最佳聚焦）的图像相关联的距离。

6. 发明申请

WO2015094496A3 METHOD FOR ASSESSING RESIDUAL ACCOMMODATION IN PRESBYOPIC EYES 审中-公开
标题翻译：用于评估预兆性眼睛残留住房的方法
公开(公告)号：WO2015094496A3
公开(公告)日：2015-11-05
申请号：PCT/US2014063929
申请日：2014-11-04
申请人： NOVARTIS AG , CAMPIN JOHN A , PETTIT GEORGE H , STANLEY DANIEL W
发明人： CAMPIN JOHN A , PETTIT GEORGE H , STANLEY DANIEL W
IPC分类号： A61B3/09
CPC分类号： A61B3/0025 , A61B3/10 , A61B3/102 , A61B3/1173
摘要： A system for determining an accommodative force in a patient includes a sensor adapted to detect motion of a lens of the patient relative to a globe of the patient's eye, a controller configured to determine an accommodative force in the patient based on the relative motion and to determine at least one parameter for an intraocular lens based on the accommodative force, and an interface adapted to output the at least one parameter for the intraocular lens.
摘要翻译：用于确定患者的调节力的系统包括适于检测患者的晶状体相对于患者的眼球的运动的传感器，配置成基于相对运动确定患者中的调节力的控制器，以及基于调节力确定用于人工晶状体的至少一个参数以及适于输出用于人工晶状体的至少一个参数的界面。

7. 发明专利

CA2615705C OPHTHALMIC DEVICE POSITIONING SYSTEM AND ASSOCIATED METHODS 未知
公开(公告)号：CA2615705C
公开(公告)日：2016-06-28
申请号：CA2615705
申请日：2006-07-26
申请人： ALCON REFRACTIVE HORIZONS INC
发明人： CAMPIN JOHN A , BOWES JOHN J
IPC分类号： A61B3/10
摘要： A system and method for determining an optimal position of an eye relative to an ophthalmic device are disclosed. One embodiment of the method includes receiving data comprising an image of a surface of an eye with the eye at a first position relative to an ophthalmic device. An edge feature in the image is located, and a sharpness calculation on the edge feature is performed using a predetermined algorithm to yield a sharpness value. The eye surface is then adjusted to a second position relative to the ophthalmic device, and the previous steps are repeated until the sharpness value is maximized, which is an indication that an optimal eye position has been achieved. An embodiment of the system includes a processor and a software package executable by the processor, the software package adapted to perform the calculations as above. Means are also provided for adjusting the eye surface to a second position relative to the ophthalmic device.

8. 发明专利

PT1968509E DETERMINAÇÃO DO POSICIONAMENTO ÓPTIMO DE DISPOSITIVOS OFTÁLMICOS ATRAVÉS DA UTILIZAÇÃO DE TÉCNICAS DE PROCESSAMENTO DE IMAGEM E DE AUTO-FOCAGEM. 未知
公开(公告)号：PT1968509E
公开(公告)日：2010-05-06
申请号：PT06846052
申请日：2006-12-21
申请人： ALCON REFRACTIVE HORIZONS INC
发明人： CAMPIN JOHN A , BOWES JOHN J
IPC分类号： A61F9/01 , A61B3/10

9. 发明专利

AT457713T 未知
公开(公告)号：AT457713T
公开(公告)日：2010-03-15
申请号：AT06846052
申请日：2006-12-21
申请人： ALCON REFRACTIVE HORIZONS INC
发明人： CAMPIN JOHN A , BOWES JOHN J
IPC分类号： A61F9/01 , A61B3/10
摘要： A system or method of positioning an ophthalmic device relative to an eye is provided. The method first obtains a series of images of an eye. In these series of images, the distance between the ophthalmic device and the eye is varied while the region of the eye image remains substantially the same. It is possible then to process these images to determine the high frequency content associated with each image. By comparing the high frequency content associated with each image, it is possible to determine which image has the largest amount of high frequency content. The high frequency content is maximized when the image is the sharpest. An optimally focused image will have the largest amount of high frequency content. By examining the high frequency content associate with the series of images is impossible to adjust the relative position and distance between the eye and the ophthalmic device to the distance associated with the image having the largest amount of high frequency content (i.e., optimally focused).

10. 发明专利

MX2007010509A SISTEMA DE DETERMINACION DE FUNCIONAMIENTO PARA LASERES REFRACTIVOS Y METODOS ASOCIADOS. 未知
公开(公告)号：MX2007010509A
公开(公告)日：2009-02-03
申请号：MX2007010509
申请日：2007-08-28
申请人： ALCON REFRACTIVE HORIZONS INC
发明人： PETTIT GEORGE H , CAMPIN JOHN A , LIEDEL KEVIN K
IPC分类号： A61B18/26
摘要： Un método para determinar un funcionamiento de un sistema láser de extirpación incluye extirpar una superficie de substrato para lograr un patrón de extirpación predeterminado. Un haz de luz se dirige a través del substrato extirpado, y la luz reflejada es recibida para detectar un patrón extirpado real, que se compara con el patrón extirpado predeterminado. La comparación resultante se muestra a un usuario de modo que el funcionamiento del sistema láser se puede determinar. Un sistema incluye un soporte que está adaptado para retener un substrato de extirpación en un plano de tratamiento. Un explorador óptico dirige un haz de luz a través del substrato extirpado y recibe la luz reflejada del mismo para detectar un patrón extirpado. Un analizador compara el patrón extirpado detectado con uno predeterminado. Una presentación en comunicación de señal con el analizador muestra una comparación del patrón extirpado detectado y el predeterminado.

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