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1. 发明申请

WO2010071764A1 MICROPOROUS MATERIAL FROM ETHYLENE-CHLOROTRIFLUOROETHYLENE COPOLYMER AND METHOD FOR MAKING SAME 审中-公开
标题翻译：乙烯 - 氯代三氟乙烯共聚物的微孔材料及其制备方法
公开(公告)号：WO2010071764A1
公开(公告)日：2010-06-24
申请号：PCT/US2009/067807
申请日：2009-12-14
申请人： 3M INNOVATIVE PROPERTIES COMPANY , MROZINSKI, James S. , SWENSON, Randall P. , WEILANDT, Karl-Dieter , HESTER, Jonathan F.
发明人： MROZINSKI, James S. , SWENSON, Randall P. , WEILANDT, Karl-Dieter , HESTER, Jonathan F.
IPC分类号： C08L27/00
CPC分类号： C08J5/18 , B01D67/002 , B01D69/02 , B01D71/26 , B01D71/32 , B01D71/76 , B01D2323/42 , B01D2325/02 , B01D2325/48 , B29C47/0021 , B29C47/8845 , B29C47/8895 , B29C67/20 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/18 , B32B15/08 , B32B27/065 , B32B27/08 , B32B27/12 , B32B27/20 , B32B27/32 , B32B27/322 , B32B2250/04 , B32B2255/26 , B32B2307/21 , B32B2307/4026 , B32B2307/518 , B32B2307/704 , B32B2307/7145 , B32B2307/734 , B32B2457/10 , C08J2327/02 , C08J2327/04 , C08J2327/12 , Y10T428/249978 , Y10T442/3366 , Y10T442/469 , Y10T442/652
摘要： Microporous material having a spherulitic matrix made from ethylene chlorotrifluoroethylene copolymer has a plurality of pores having an average pore size greater than about 0.01 micrometer. The material is made by thermally induced phase separation (TIPS) process that includes melt mixing ethylene chlorotrifluoroethylene copolymer, diluent and nucleating agent to provide a melt mixed composition; shaping the melt mixed composition; cooling the shaped melt mixed composition to induce phase separation of the ethylene chlorotrifluoroethylene copolymer to provide a phase separated material; and stretching the phase separated material to provide the microporous material. The microporous material may be incorporated into articles and the articles may include one, two or more layers of microporous material.
摘要翻译：具有由乙烯氯三氟乙烯共聚物制成的球晶基质的微孔材料具有多个平均孔径大于约0.01微米的孔。该材料通过热诱导相分离（TIPS）方法制备，其包括熔融混合乙烯氯三氟乙烯共聚物，稀释剂和成核剂以提供熔融混合组合物; 成型熔融混合组合物; 冷却成型的熔融混合组合物以诱导乙烯氯三氟乙烯共聚物的相分离以提供相分离的材料; 并拉伸相分离的材料以提供微孔材料。微孔材料可以并入制品中，并且制品可以包括一层，两层或更多层微孔材料。

2. 发明申请

WO2022180572A1 CHARGED DEPTH FILTER FOR THERAPEUTIC BIOTECHNOLOGY MANUFACTURING PROCESS 审中-公开
公开(公告)号：WO2022180572A1
公开(公告)日：2022-09-01
申请号：PCT/IB2022/051648
申请日：2022-02-24
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： LIN, Kuan-Yin , VAIL, Andrew W. , O'NEAL, Daniel J. , NAKAMURA, Masayuki , HESTER, Jonathan F. , DASHARATHI, Kannan , VOLOSHIN, Alexei M.
IPC分类号： B01D15/08 , B01D15/34 , B01D15/36
摘要： A charged depth filter for removing cells and/or cellular debris from a biopharma feedstock having a first functionalized nonwoven layer having a first calculated pore size and a first dynamic charge capacity; a second functionalized nonwoven layer having a second calculated pore size and a second dynamic charge capacity positioned after the first functionalized nonwoven layer in the direction of the biopharma feedstock flow, and wherein the first calculated pore size is greater than the second calculated pore size, and the first dynamic charge capacity is less than the second dynamic charge capacity.

3. 发明申请

WO2013019765A9 RECHARGEABLE ELECTROCHEMICAL CELLS 审中-公开
公开(公告)号：WO2013019765A9
公开(公告)日：2013-02-07
申请号：PCT/US2012/048922
申请日：2012-07-31
申请人： 3M INNOVATIVE PROPERTIES COMPANY , ASTLE, Robert E. , HESTER, Jonathan F. , ZHENG, Dian
发明人： ASTLE, Robert E. , HESTER, Jonathan F. , ZHENG, Dian
IPC分类号： C02F1/469 , C02F1/42 , B01J47/08 , B01J47/12 , B01J49/00 , A47J37/00
摘要： Provided are electrochemical devices that are rechargeable, where the regeneration techniques are based on a batch-wise application of current or current density to the cells, where there are a service mode where no current or current density is applied and a recharge mode where a current or current density is applied. Electrochemical and EDI systems according to the embodiments herein are suitable for deionization and/or purification of typical municipal tap quality water in applications where demand for purified, low-TDS water is intermittent. Such operations avoid the use of chemical additions for regeneration purposes. In addition the cells provided herein are amenable to small footprints for consumer and commercial applications such as: dishwashers, washing machines, coffee and espresso makers, ice makers, steam tables, car wash water sources, and steamers.

4. 发明申请

WO2020128797A1 METHOD FOR TESTING A CHROMATOGRAPHY DEVICE USED FOR ION EXCHANGE 审中-公开
公开(公告)号：WO2020128797A1
公开(公告)日：2020-06-25
申请号：PCT/IB2019/060866
申请日：2019-12-16
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： HESTER, Jonathan F. , OLSON, Eric J. , PORBENI, Francis E. , VAIL, Andrew W. , VOLOSHIN, Alexei M.
IPC分类号： G01N30/88 , G01N30/96
摘要： Described herein is method for testing an ion exchange chromatography device. The method includes monitoring both a binding and a non-binding species and determining their breakthrough point to determine a net breakthrough value. The method can be used to determine the integrity of the chromatography device, ensure that the chromatography device possesses the expected adsorbent capacity, and/or determine viral clearance of the chromatography device.

5. 发明申请

WO2017069965A1 FILTRATION MEDIUM SEQUENCE FOR BIOMATERIAL PURIFICATION 审中-公开
标题翻译：用于生物材料纯化的过滤介质序列
公开(公告)号：WO2017069965A1
公开(公告)日：2017-04-27
申请号：PCT/US2016/056326
申请日：2016-10-11
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： HESTER, Jonathan F. , CASTRO FORERO, Angelines A. , JELLUM, Gregory M. , RASMUSSEN, Jerald K. , SESHADRI, Kannan , WALLER, Clinton P., Jr.
IPC分类号： B01D67/00 , B01D69/10 , B01D71/40 , B01D71/78
CPC分类号： B01D67/009 , B01D69/10 , B01D71/40 , B01D71/78 , B01D2323/385 , B01D2325/16 , B01D2325/42
摘要： Described herein is a filtration media comprising: (i) a first filtration medium comprising an anion exchange nonwoven substrate, wherein the anion exchange nonwoven substrate comprises a plurality of quaternary ammonium groups; and (ii) a second filtration medium comprising a functionalized microporous membrane wherein the functionalized microporous membrane comprises a plurality of guanidyl groups; wherein the first filtration medium is positioned upstream of the second filtration medium.
摘要翻译：本文描述了一种过滤介质，其包含：（i）包含阴离子交换非织造基底的第一过滤介质，其中所述阴离子交换非织造基底包含多个季铵基团; 和（ii）包含官能化微孔膜的第二过滤介质，其中所述官能化微孔膜包含多个胍基; 其中第一过滤介质位于第二过滤介质的上游。

6. 发明申请

WO2014093743A1 CONSTRUCTIONS FOR FLUID MEMBRANE SEPARATION DEVICES 审中-公开
标题翻译：流体膜分离装置的结构
公开(公告)号：WO2014093743A1
公开(公告)日：2014-06-19
申请号：PCT/US2013/074873
申请日：2013-12-11
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： HESTER, Jonathan F. , CASTRO, Gustavo H. , HERDTLE, Thomas , SONG, Liming
IPC分类号： B01D63/08 , C07C7/144 , C07C31/08
CPC分类号： B01D69/10 , B01D63/082 , B01D67/0002 , B01D71/26 , B01D71/68 , B01D2313/08 , B01D2319/02 , C07C29/76 , C07C31/08
摘要： Described herein is a construction comprising (a) a support sheet having a base, comprising (i) a plurality of rails extending from the base wherein each rail of the plurality of rails extends continuously down a length of the support sheet and each rail comprises a first side surface and an opposing second side surface and a top surface; and (ii) a plurality of first protrusions extending from the base, wherein the plurality of first protrusions are located between the plurality of rails; and (b) a selectively permeable membrane having a first major membrane surface contacting at least the top surface of at least two rails enclosing a flow channel having a height extending between the base of the support sheet and the first major membrane surface, wherein the plurality of protrusions change the height of the flow channel along its length along the longitudinal axis of the flow channel.
摘要翻译：这里描述的是一种结构，其包括（a）具有基部的支撑片，该支撑片包括（i）从基部延伸的多个导轨，其中多个导轨中的每个导轨连续地向下延伸支撑片和每个导轨包括第一侧表面和相对的第二侧表面以及顶表面; 和（ii）从所述基部延伸的多个第一突起，其中所述多个第一突起位于所述多个导轨之间; （b）具有第一主膜表面和第二主膜表面的选择性渗透膜，所述第一主膜表面至少接触包围流动通道的至少两个导轨的顶表面，所述流动通道具有在所述支撑片的基部和所述第一主膜表面之间延伸的高度，其中，所述多个突出物沿流动通道的纵向轴线改变流动通道沿其长度的高度。

7. 发明申请

WO2013162695A1 NONWOVEN ARTICLE GAFTER WITH COPOLYMER 审中-公开
标题翻译：非挥发性物品与共聚物
公开(公告)号：WO2013162695A1
公开(公告)日：2013-10-31
申请号：PCT/US2013/027756
申请日：2013-02-26
申请人： 3M INNOVATIVE PROPERTIES COMPANY , BERRIGAN, Michael R. , HESTER, Jonathan F. , WALLER, Clinton P. , WEISS, Douglas E.
发明人： BERRIGAN, Michael R. , HESTER, Jonathan F. , WALLER, Clinton P. , WEISS, Douglas E.
IPC分类号： D06M14/08 , D06M14/10 , D06M14/26 , D06M14/28 , B01D67/00 , B01D69/10 , C08J9/40 , C08L51/00
CPC分类号： B01D67/0093 , B01D67/009 , B01D69/10 , B01D2323/36 , B01D2323/385 , D06M14/26 , D06M14/28 , Y10T442/20 , Y10T442/291
摘要： A functionalized nonwoven substrate and methods for preparing the same are described. The functionalized substrates are useful in selectively filtering and removing biological materials, such as biocontaminates, from biological samples.
摘要翻译：描述了功能化非织造基底及其制备方法。功能化底物可用于从生物样品中选择性过滤和除去生物材料，例如生物污染物。

8. 发明申请

WO2021229327A1 MEMBRANE SEALING LAYER AND SPACER RING FOR VIRAL CLEARANCE CHROMATOGRAPHY DEVICE 审中-公开
公开(公告)号：WO2021229327A1
公开(公告)日：2021-11-18
申请号：PCT/IB2021/053327
申请日：2021-04-22
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： DASHARATHI, Kannan , HESTER, Jonathan F. , JELLUM, Gregory M. , CASTRO FORERO, Angelines
IPC分类号： B01D15/22 , G01N30/60 , B01D69/06 , B01D63/08 , B01J20/28 , G01N30/52 , G01N30/38 , B01D61/14 , B01D71/56
摘要： A chromatography device having a housing having an inlet and an outlet. At least two layers of media disposed between the inlet and the outlet inside of the housing forming a media stack, with at least one of the layers comprising a functionalized layer. An optional spacer ring disposed between the two layers of media forming an air gap between them. A non-functionalized sealing layer disposed between the inlet and the outlet inside of the housing as the last layer of media in the media stack within the housing as a fluid passes from the inlet to the outlet through the media stack. A margin of the sealing layer in contact with the housing; the margin being compressed by the housing forming a compressive seal to prevent fluid from leaking to the outlet past the compressive seal.

9. 发明申请

WO2021209851A1 FLOW-THROUGH PROCESSES AND DEVICES FOR PURIFYING A TARGET MOLECULE 审中-公开
公开(公告)号：WO2021209851A1
公开(公告)日：2021-10-21
申请号：PCT/IB2021/052739
申请日：2021-04-01
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： VAIL, Andrew W. , ATAN, Semra C. , RASMUSSEN, Jerald K. , VOLOSHIN, Alexei M. , HESTER, Jonathan F.
IPC分类号： C07K1/18 , C07K1/36
摘要： Flow-through processes for purifying a target molecule (e.g., antibodies, enzymes, and hormones, particularly a monoclonal antibody) from a biological solution (e.g., a neutralized viral inactivation pool) in a sample that includes the target molecule, and devices for carrying out such processes.

10. 发明申请

WO2014047016A1 FLUID SEPARATION UNIT 审中-公开
标题翻译：流体分离单元
公开(公告)号：WO2014047016A1
公开(公告)日：2014-03-27
申请号：PCT/US2013/060024
申请日：2013-09-17
申请人： 3M INNOVATIVE PROPERTIES COMPANY , HENDERSON, John W. , HAISLET, Brady P. , HANSEN, Brent R. , HESTER, Jonathan F. , JELLUM, Gregory M. , NIE, Qihong , REED, John F. , SCHEIBNER, John B. , SLAMA, David F. , TURCH, Steven E.
发明人： HENDERSON, John W. , HAISLET, Brady P. , HANSEN, Brent R. , HESTER, Jonathan F. , JELLUM, Gregory M. , NIE, Qihong , REED, John F. , SCHEIBNER, John B. , SLAMA, David F. , TURCH, Steven E.
IPC分类号： B01D63/08 , B01D65/00 , B01D61/00
CPC分类号： B01D71/68 , B01D19/0031 , B01D53/228 , B01D61/08 , B01D61/18 , B01D63/082 , B01D65/003 , B01D67/0002 , B01D71/10 , B01D71/26 , B01D71/32 , B01D71/34 , B01D71/38 , B01D71/50 , B01D71/56 , B01D71/58 , B01D2053/221 , B01D2313/08 , B01D2313/14
摘要： Described herein is a membrane separation module and articles and methods thereof, wherein the membrane separation module has a series of repeating layers, each layer comprising (a) a selectively permeable membrane; and (b) at least one support layer, wherein the support layer comprises a plurality of flow channels and a plurality of rails extending from the support layer, wherein the sides of two adjacent rails form a flow channel, wherein the plurality of rails on the support layer comprise a thermoplastic polymer at the distal end of at least a portion of the plurality of rails, and wherein the distal end of the plurality of rails contacts the selectively permeable membrane to form a bonded stack.
摘要翻译：本文描述的是膜分离模块及其制品和方法，其中膜分离模块具有一系列重复层，每层包括（a）选择性渗透膜; 和（b）至少一个支撑层，其中所述支撑层包括多个流动通道和从所述支撑层延伸的多个轨道，其中两个相邻轨道的侧面形成流动通道，其中所述多个轨道支撑层在多个轨道的至少一部分的远端处包括热塑性聚合物，并且其中多个轨道的远端接触选择性渗透膜以形成键合叠层。

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