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1. 发明申请

US20150233861A1 TEST SENSOR WITH MULTIPLE SAMPLING ROUTES 审中-公开
标题翻译：具有多个采样路径的测试传感器
公开(公告)号：US20150233861A1
公开(公告)日：2015-08-20
申请号：US14184764
申请日：2014-02-20
申请人： Xiaohua Cai , Hongli Che , Shaobo Li
发明人： Xiaohua Cai , Hongli Che , Shaobo Li
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： An improved disposable electrochemical test sensor designed to facilitate sampling of fluid samples. It has a fluid chamber having a novel extra wide sampling entrance. The chamber provides a reservoir from which a sample fluid can be drawn into the chamber through capillary action. The novel extra wide sampling entrance of the test sensor provided by the present invention can draw blood into the chamber not only from the front of the sampling entrance as usual in convenient sensors, but also from the top, bottom, left corner and right corner of the sampling entrance. Thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger.
摘要翻译：改进的一次性电化学测试传感器设计用于方便采样液体样品。它具有流体室，具有新颖的超宽采样入口。该室提供储存器，通过毛细管作用，样品流体可从该储存器吸入室中。本发明提供的测试传感器的新颖的超宽采样入口，不仅可以像往常一样在便利的传感器中从血液进入采样入口的前方，还可以从上，下，左，抽样入口。因此，它允许容易地对具有小体积的样品进行定位，拾取涂抹的样品，并且对于将传感器的尖端堵塞到用户手指中的用户更容忍。

2. 发明申请

US20150198554A1 DISPOSABLE TEST SENSOR 有权
标题翻译：不可测试的传感器
公开(公告)号：US20150198554A1
公开(公告)日：2015-07-16
申请号：US14153654
申请日：2014-01-13
申请人： Xiaohua Cai , Hongli Che , Shaobo Li
发明人： Xiaohua Cai , Hongli Che , Shaobo Li
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： The present invention relates to disposable test sensors having improved sample application and measuring properties and their uses for detection, preferably, quantitative measurement, of analyte in a liquid sample like blood. In particular, the invention provides for an electrochemical biosensor which has a thin-layer fluid chamber having funnel-like shape with a novel extra wide opening as sampling entrance and a vent opening at the tip of the chamber for air escape. The thin-layer fluid chamber provides a reservoir from which a sample fluid can be drawn into it through capillary action. The extra wide sampling entrance provided by the present invention can draw blood into the chamber through any part of the opening, thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger.
摘要翻译：本发明涉及一次性测试传感器，其具有改进的样品应用和测量性质及其用于检测，优选地定量测量液体样品（例如血液）中的分析物的用途。特别地，本发明提供了一种电化学生物传感器，其具有具有漏斗状形状的薄层流体室，其具有作为取样入口的新颖的宽敞开口，并且在室的顶部具有用于空气逸出的通风口。薄层流体室提供储存器，通过毛细管作用可将样品流体从该储存器吸入。本发明提供的超宽采样入口可以通过开口的任何部分将血液吸入腔室，从而容易地以小体积对准样品，拾取涂抹样品，并且对于堵塞尖端的使用者更容忍传感器进入用户的手指。

3. 发明授权

US09518951B2 Disposable test sensor with improved sampling entrance 有权
标题翻译：一次性测试传感器，具有改进的取样入口
公开(公告)号：US09518951B2
公开(公告)日：2016-12-13
申请号：US14099418
申请日：2013-12-06
申请人： Xiaohua Cai , Hongli Che , Shaobo Li
发明人： Xiaohua Cai , Hongli Che , Shaobo Li
IPC分类号： G01N27/327 , B01L3/00
CPC分类号： G01N27/3272 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L2200/0621 , B01L2200/0684 , B01L2200/16 , B01L2300/0645 , B01L2300/0663 , B01L2300/0825 , B01L2300/0887 , B01L2300/16 , B01L2300/161 , B01L2400/0406 , B01L2400/0694
摘要： A disposable electrochemical test sensor designed to facilitate sampling of fluid samples. It has a fluid chamber having a novel extra wide sampling entrance, but no additional air escape vent. The chamber provides a reservoir from which a sample fluid can be drawn into the chamber through capillary action. The extra wide sampling entrance provided by the present invention can draw blood into the chamber through any part of the opening, thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger.
摘要翻译：一次性电化学测试传感器设计用于方便采样流体样品。它具有流体室，具有新颖的超宽采样入口，但没有额外的空气逸出口。该室提供储存器，通过毛细管作用，样品流体可从该储存器吸入室中。本发明提供的超宽采样入口可以通过开口的任何部分将血液吸入腔室，从而容易地以小体积对准样品，拾取涂抹样品，并且对于堵塞尖端的使用者更容忍传感器进入用户的手指。

4. 发明申请

US20150160150A1 DISPOSABLE TEST SENSOR WITH IMPROVED SAMPLING ENTRANCE 有权
标题翻译：具有改进的取样入口的可检测测试传感器
公开(公告)号：US20150160150A1
公开(公告)日：2015-06-11
申请号：US14099418
申请日：2013-12-06
申请人： Xiaohua Cai , Hongli Che , Shaobo Li
发明人： Xiaohua Cai , Hongli Che , Shaobo Li
IPC分类号： G01N27/327
CPC分类号： G01N27/3272 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L2200/0621 , B01L2200/0684 , B01L2200/16 , B01L2300/0645 , B01L2300/0663 , B01L2300/0825 , B01L2300/0887 , B01L2300/16 , B01L2300/161 , B01L2400/0406 , B01L2400/0694
摘要： A disposable electrochemical test sensor designed to facilitate sampling of fluid samples. It has a fluid chamber having a novel extra wide sampling entrance, but no additional air escape vent. The chamber provides a reservoir from which a sample fluid can be drawn into the chamber through capillary action. The extra wide sampling entrance provided by the present invention can draw blood into the chamber through any part of the opening, thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger. The extra wide sampling entrance provided by the present invention also serves as air escape vent.
摘要翻译：一次性电化学测试传感器设计用于方便采样流体样品。它具有流体室，具有新颖的超宽采样入口，但没有额外的空气逸出口。该室提供储存器，通过毛细管作用，样品流体可从该储存器吸入室中。本发明提供的超宽采样入口可以通过开口的任何部分将血液吸入腔室，从而容易地以小体积对准样品，拾取涂抹样品，并且对于堵塞尖端的使用者更容忍传感器进入用户的手指。本发明提供的超宽采样入口还用作排气口。

5. 发明授权

US09039874B2 Disposable urea sensor and system for determining creatinine and urea nitrogen-to-creatinine ratio in a single device 有权
标题翻译：一次性尿素传感器和用于测定单个装置中肌酐和尿素氮对肌酐比例的系统
公开(公告)号：US09039874B2
公开(公告)日：2015-05-26
申请号：US14077620
申请日：2013-11-12
申请人： Handani Winarta , Jianhong Pei , Mary Lauro , Chung Chang Young , Xiaohua Cai
发明人： Handani Winarta , Jianhong Pei , Mary Lauro , Chung Chang Young , Xiaohua Cai
IPC分类号： C12Q1/00 , G01N27/327
CPC分类号： C12Q1/005 , G01N27/3271
摘要： A disposable urea sensor has a laminated body having a fluid sample inlet end and an electrical contact end, a fluid sample inlet, a substantially flat sample chamber in communication between the fluid sample inlet and a vent opening, the sample chamber being adapted to collect a fluid sample through the fluid sample inlet, a working electrode and a reference electrode within the sample chamber, and a reagent matrix disposed on the working electrode wherein the reagent matrix contains urease.
摘要翻译：一次性尿素传感器具有层压体，其具有流体样品入口端和电接触端，流体样品入口，在流体样品入口和通气口之间连通的基本平坦的样品室，样品室适于收集流体样品通过流体样品入口，样品室内的工作电极和参比电极，以及设置在工作电极上的试剂基质，其中试剂基质含有脲酶。

6. 发明申请

US20140069823A1 Disposable urea sensor and system for determining creatinine and urea nitrogen-to-creatinine ratio in a single device 审中-公开
标题翻译：一次性尿素传感器和用于测定单个装置中肌酐和尿素氮对肌酐比例的系统
公开(公告)号：US20140069823A1
公开(公告)日：2014-03-13
申请号：US14077620
申请日：2013-11-12
申请人： Handani Winarta , Jianhong Pei , Mary Lauro , Chung Chang Young , Xiaohua Cai
发明人： Handani Winarta , Jianhong Pei , Mary Lauro , Chung Chang Young , Xiaohua Cai
IPC分类号： C12Q1/00
CPC分类号： C12Q1/005 , G01N27/3271
摘要： A disposable urea sensor has a laminated body having a fluid sample inlet end and an electrical contact end, a fluid sample inlet, a substantially flat sample chamber in communication between the fluid sample inlet and a vent opening, the sample chamber being adapted to collect a fluid sample through the fluid sample inlet, a working electrode and a reference electrode within the sample chamber, and a reagent matrix disposed on the working electrode wherein the reagent matrix contains urease.
摘要翻译：一次性尿素传感器具有层压体，其具有流体样品入口端和电接触端，流体样品入口，在流体样品入口和通气口之间连通的基本平坦的样品室，样品室适于收集流体样品通过流体样品入口，样品室内的工作电极和参比电极，以及设置在工作电极上的试剂基质，其中试剂基质含有脲酶。

7. 发明申请

US20100110934A1 OPTIMIZED CACHE CONSISTENCY ALGORITHM IN A POINT-TO-POINT INTERCONNECTED MULTIPLE PROCESSOR SYSTEM 有权
标题翻译：一个点到点互连的多处理器系统中优化的高速缓存一致性算法
公开(公告)号：US20100110934A1
公开(公告)日：2010-05-06
申请号：US11995047
申请日：2006-09-20
申请人： Yufu Li , Xiaohua Cai
发明人： Yufu Li , Xiaohua Cai
IPC分类号： H04L12/28 , G06F12/00 , G06F12/08
CPC分类号： G06F12/0831
摘要： A spanning tree is assigned to a processing node for each processing node in a point-to-point network that connects a plurality of processing nodes. The spanning tree uses the processing nodes as vertices and links of the network as edges. Each processing node includes input snoop ports that can be configured as either terminating or forwarding. According to the assigned spanning trees and the configuration of the input snoop ports, the network routes snoop messages efficiently and without conflicts.
摘要翻译：生成树被分配给连接多个处理节点的点对点网络中的每个处理节点的处理节点。生成树使用处理节点作为边缘的网络的顶点和链接。每个处理节点包括可配置为终止或转发的输入侦听端口。根据分配的生成树和输入snoop端口的配置，网络可以有效且无冲突地发送snoop报文。

8. 再颁专利

USRE41264E1 Biosensor with peroxidase enzyme 有权
标题翻译：具有过氧化物酶的生物传感器
公开(公告)号：USRE41264E1
公开(公告)日：2010-04-27
申请号：US11494805
申请日：2006-07-27
申请人： Xiaohua Cai , Handani Winarta , Chung Chang Young
发明人： Xiaohua Cai , Handani Winarta , Chung Chang Young
IPC分类号： G01N27/327
CPC分类号： C12Q1/34 , C12Q1/004 , C12Q1/006 , C12Q1/26 , C12Q1/28 , Y10T29/49002
摘要： An improved biosensor having at least a first working electrode and a first electrode material disposed on the first working electrode. The first electrode material is a mixture made by combining at least one enzyme where the at least one enzyme is a capable of reacting with the analyte to be measured, a redox mediator capable of reacting with a product of an enzymatic reaction or a series of enzymatic reactions involving the at least one enzyme, a peroxidase capable of catalyzing a reaction involving the redox mediator where the redox mediator is oxidized, a binder and a surfactant.
摘要翻译：一种改进的生物传感器，具有至少第一工作电极和设置在第一工作电极上的第一电极材料。第一电极材料是通过将至少一种酶与待测分析物反应的至少一种酶，能够与酶反应或一系列酶反应的产物反应的氧化还原介体涉及至少一种酶的反应物，能够催化涉及氧化还原介体被氧化的氧化还原介体的反应的过氧化物酶，粘合剂和表面活性剂。

9. 发明授权

US07648624B2 Oxygen sensor 有权
标题翻译：氧传感器
公开(公告)号：US07648624B2
公开(公告)日：2010-01-19
申请号：US11161180
申请日：2005-07-26
申请人： Xiaohua Cai , Kara Alesi , Chung Chang Young
发明人： Xiaohua Cai , Kara Alesi , Chung Chang Young
IPC分类号： G01N27/26 , G01F1/64
CPC分类号： G01N27/3272
摘要： An oxygen sensor has a laminated body with a fluid sample inlet end and an electrical contact end, a fluid sample inlet, a substantially flat test chamber communicating with the fluid sample inlet where the test chamber is adapted to collect a fluid sample through the sample fluid inlet, a working electrode and a reference electrode within the test chamber, and a reagent matrix disposed on the working electrode where the reagent matrix contains an oxidase, a reduced form of a redox mediator and a peroxidase.
摘要翻译：氧传感器具有层流体，其具有流体样品入口端和电接触端，流体样品入口，与流体样品入口连通的基本平坦的测试室，其中测试室适于通过样品流体收集流体样品入口，测试室内的工作电极和参比电极，以及设置在工作电极上的试剂基质，其中试剂基质含有氧化酶，还原形式的氧化还原介体和过氧化物酶。

10. 发明授权

US07611621B2 Disposable oxygen sensor and method for correcting oxygen effect on oxidase-based analytical devices 有权
标题翻译：一次性氧传感器和氧化酶基分析装置氧效应的校正方法
公开(公告)号：US07611621B2
公开(公告)日：2009-11-03
申请号：US11160193
申请日：2005-06-13
申请人： Xiaohua Cai , Kara Alesi , Chung Chang Young
发明人： Xiaohua Cai , Kara Alesi , Chung Chang Young
IPC分类号： G01N27/327 , C12Q1/26 , C12Q1/28 , C12Q1/54
CPC分类号： C12Q1/005 , A61B5/14546 , A61B5/1486 , C12Q1/006 , G01N27/3274
摘要： A system and method for correcting the oxygen effect on oxidase-based analyte sensors includes an oxygen sensor with a working electrode, a reagent matrix disposed on at least the working electrode that contains a reduced form of a redox mediator, an oxidase and a peroxidase, an oxidase-based analyte sensor, a means for determining the oxygen concentration in a portion of a fluid sample using the oxygen sensor, means for determining an analyte concentration in another portion of the fluid sample using the oxidase-based analyte sensor, and means for using the oxygen concentration in the fluid sample to determine a corrected analyte concentration in the fluid sample.
摘要翻译：用于校正氧化酶基分析物传感器的氧效应的系统和方法包括具有工作电极的氧传感器，设置在至少包含还原形式的氧化还原介体，氧化酶和过氧化物酶的至少工作电极上的试剂基质，基于氧化酶的分析物传感器，用于使用氧传感器确定流体样品的一部分中的氧浓度的装置，用于使用基于氧化酶的分析物传感器确定流体样品的另一部分中的分析物浓度的装置，以及用于使用流体样品中的氧浓度来确定流体样品中校正的分析物浓度。

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