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1. 发明专利

IL143739A DETECTION OF HEPATITIS B VIRUS 未知
公开(公告)号：IL143739A
公开(公告)日：2006-09-05
申请号：IL14373901
申请日：2001-06-13
申请人： GOVERNMENT OF THE REPUBLIC OF , OON CHONG JIN , CHEN WEI NING
发明人： OON CHONG JIN , CHEN WEI NING
IPC分类号： G01N33/53 , A61K39/395 , A61P31/12 , C07K16/08 , C12N7/00 , C12N7/01 , C12N15/09 , C12Q1/68 , C12Q1/70 , C12R1/93 , G01N33/566 , G01N33/569 , G01N33/576
摘要： The present invention relates generally to a nucleic acid-based assay to detect the presence of a viral pathogen and, in particular, hepatitis B virus. More particularly, the present invention provides a single-step amplification assay to detect hepatitis B viral nucleic acid sequences. The assay of the present invention is readily adaptable for automation and permits the rapid through-put of samples to be tested. The present invention further provides agents useful for performing a nucleic acid-based detection assay for hepatitis B virus and a kit comprising said agents.

2. 发明专利

DE202010006598U1 Vorrichtung für Mikroskopie 未知
公开(公告)号：DE202010006598U1
公开(公告)日：2010-09-02
申请号：DE202010006598
申请日：2010-05-11
申请人： WEI NING
IPC分类号： G02B21/24

3. 发明专利

IL142288A METHOD FOR ASSAYING HUMAN HEPATITIS B VIRUS (HBV) DNA POLYMERASE 未知
公开(公告)号：IL142288A
公开(公告)日：2006-12-31
申请号：IL14228801
申请日：2001-03-27
申请人： GOVERNMENT OF THE REPUBLIC OF , CHONG JIN OON , WEI NING CHEN , GEK KEOW LIM , AI LIN LEONG
发明人： CHONG JIN OON , WEI NING CHEN , GEK KEOW LIM , AI LIN LEONG
IPC分类号： G01N33/50 , C12N9/10 , C12N9/12 , C12N15/09 , C12P19/34 , C12P21/00 , C12Q1/48 , C12Q1/68 , C12Q1/70 , G01N27/447 , G01N33/15 , G01N33/48
摘要： The present invention provides an in vitro activity assay for human hepatitis B virus (HBV) DNA polymerase, which comprises using, as the 5' oligonucleotide in PCR amplification of HBV DNA polymerase from a sample, an oligonucleotide into which has been incorporated the SP6 viral polymerase promoter, directly transcribing and translating the PCR products in the presence of a radio-labelled agent and measuring the priming of the HBV DNA polymerase. The present invention also provides the use of such an assay to assay activity of various serum samples, to screen for inhibitors of the HBV DNA polymerase and to test and/or screen potential anti-HBV drugs for their ability to inhibit DNA priming activity of human HBV DNA polymerase.

4. 发明专利

TW201540207A 具多功能口袋之刷手服审中-公开
公开(公告)号：TW201540207A
公开(公告)日：2015-11-01
申请号：TW103140348
申请日：2014-11-21
申请人：魏寧韋 , WEI, NING WEI
发明人：魏寧韋 , WEI, NING WEI
IPC分类号： A41D13/12
摘要：現今，刷手服的用途廣泛，相較於以往只於手術室內穿戴，如今已成為醫療機構人員之工作服，有鑑於此，本發明之目的為提升刷手服的實用性、便利性及功能性。其基本元素包含一刷手服及一至多個口袋；該刷手服包含一刷手服之上衣及一刷手服之褲子，該一至多個口袋為多功能口袋。本人發明為將刷手服的口袋增設開閉手段，添加開閉手段，不僅可避免口袋內的物品滑出、摔落、撞擊或其他因素所造成的損害，亦可避免口袋內物品掉至醫療行為時的無菌區域而造成汙染。另可增設內袋，以利隔層，方便使用者分層放置不同物件。除此之外，另可增設筆袋。以上之設計皆能有效提升刷手服使用時之實用性、便利性及功能性，提高醫療人員工作時的效率，使醫療行為更為流暢。
简体摘要：现今，刷手服的用途广泛，相较于以往只于手术室内穿戴，如今已成为医疗机构人员之工作服，有鉴于此，本发明之目的为提升刷手服的实用性、便利性及功能性。其基本元素包含一刷手服及一至多个口袋；该刷手服包含一刷手服之上衣及一刷手服之裤子，该一至多个口袋为多功能口袋。本人发明为将刷手服的口袋增设开闭手段，添加开闭手段，不仅可避免口袋内的物品滑出、摔落、撞击或其他因素所造成的损害，亦可避免口袋内物品掉至医疗行为时的无菌区域而造成污染。另可增设内袋，以利隔层，方便用户分层放置不同对象。除此之外，另可增设笔袋。以上之设计皆能有效提升刷手服使用时之实用性、便利性及功能性，提高医疗人员工作时的效率，使医疗行为更为流畅。

5. 实用新型

TWM499782U 具多功能口袋之刷手服有权
公开(公告)号：TWM499782U
公开(公告)日：2015-05-01
申请号：TW103220655
申请日：2014-11-21
申请人：魏寧韋 , WEI, NING WEI
发明人：魏寧韋 , WEI, NING WEI
IPC分类号： A41D13/12

6. 实用新型

TWM487642U 具拉鍊且多功能之口袋之刷手服失效
简体标题：具拉链且多功能之口袋之刷手服
公开(公告)号：TWM487642U
公开(公告)日：2014-10-11
申请号：TW102222068
申请日：2013-11-26
申请人：魏寧韋 , WEI, NING WEI
发明人：魏寧韋 , WEI, NING WEI
IPC分类号： A41D13/12

7. 发明申请

WO2012077004A2 WETNESS SENSOR FOR USE IN AN ABSORBENT ARTICLE 审中-公开
标题翻译：用于吸收物品的湿度传感器
公开(公告)号：WO2012077004A2
公开(公告)日：2012-06-14
申请号：PCT/IB2011/054837
申请日：2011-10-31
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , WEI, Ning , SONG, Xuedong
发明人： WEI, Ning , SONG, Xuedong
IPC分类号： A61F13/42 , A61F13/511 , A61F13/514 , A61F13/53 , A61L15/56
CPC分类号： A61L15/56 , A61F13/42 , A61F2013/422
摘要： A wetness sensor for an absorbent article that is formed from an ink is provided. The ink includes a proton-accepting chromogen and a proton-donating agent (or color developer). Prior to use, the ink is generally dry and in a protonated form so that it has a visible color. However, upon contact with bodily fluids {e.g., urine, fecal matter, mucus, menses, vaginal fluid, etc.), water in the fluid can lead to deprotonation of the chromogen, thereby resulting in a shift of the absorption maxima of the chromogen towards either the red {"bathochromic shift") or blue end of the spectrum ("hypsochromic shift"). To increase the rate of the color change during use, the present inventors have discovered that a specific type of proton-donating agent may be employed. More particularly, the proton- donating agent is an aliphatic carboxylic acid that is highly soluble in the bodily fluid (e.g., urine), and therefore results in a color change that is very rapid and may be detected within a relatively short period of time. The extent of the color change is also generally sufficient to provide a "real-time" indication of wetness on the absorbent article.
摘要翻译：提供由油墨形成的吸收性物品的湿度传感器。油墨包括质子接受色原子和质子供体剂（或显色剂）。在使用之前，油墨通常是干燥的并且是质子化形式，使得它具有可见的颜色。然而，当与体液（例如尿液，粪便，粘液，月经，阴道液等）接触时，液体中的水会导致色原因的去质子化，从而导致色原体的吸收最大值的偏移朝向红色（“红移”）或蓝光端（“色变”）。为了增加使用期间的颜色变化率，本发明人已经发现可以使用特定类型的质子递送剂。更具体地，质子供体剂是高度可溶于体液（例如尿液）的脂族羧酸，因此导致颜色变化非常快并且可以在相对短的时间内检测。颜色变化的程度通常也足以在吸收制品上提供湿度的“实时”指示。

8. 发明申请

WO2012023071A3 DEHYDRATION SENSORS WITH ION-RESPONSIVE AND CHARGED POLYMERIC SURFACTANTS 审中-公开
标题翻译：具有反应性和充电聚合物表面活性剂的脱水传感器
公开(公告)号：WO2012023071A3
公开(公告)日：2012-06-07
申请号：PCT/IB2011053313
申请日：2011-07-25
申请人： KIMBERLY CLARK CO , SONG XUEDONG , WEI NING , PHILLIPS RONNIE L
发明人： SONG XUEDONG , WEI NING , PHILLIPS RONNIE L
IPC分类号： G01N33/493 , G01N21/80 , G01N31/22 , G01N33/52
CPC分类号： G01N33/558 , A61F13/42 , A61F13/84 , A61F2013/00429 , A61F2013/0094 , A61F2013/00948 , A61F2013/15081 , A61F2013/15154 , A61F2013/8473
摘要： A lateral flow assay device for determining the relative ionic strength of urine is described. The device includes a buffering zone having a polyelectrolyte disposed therein, and an indicator zone having a pH indicator non-diffusively immobilized therein, the indicator zone being separate from the buffering zone and positioned adjacent to and in fluid communication with the buffering zone. A detection zone is part of the buffering zone, and has a buffering component comprising a weak polymeric acid and weak polymeric base with a pKa = 10-3, and a class of charged polymeric surfactants that are responsive to relative ion concentrations in a sample solution, and a charged pH indicator with a charge opposite to that of the charged polymeric surfactant. The charged polymeric surfactant is soluble in amounts of greater than or equal to about 1% by weight (= 1wt. % solute) in water and aqueous solutions of low ionic concentration of = 0.1 wt. % salts, but insoluble ( 0.1 wt. % salts. The present invention also describes absorbent articles incorporating such an assay device and methods of monitoring dehydration or testing ion strength of a urine sample using such a test format.
摘要翻译：描述了用于确定尿液的相对离子强度的侧流测定装置。该装置包括其中布置有聚电解质的缓冲区和具有非扩散固定在其中的pH指示剂的指示区，指示区与缓冲区分离并且定位成与缓冲区相邻并且与缓冲区流体连通。检测区是缓冲区的一部分，并且具有包含弱聚合酸和pKa = 10-3的弱聚合物碱的缓冲组分和对样品溶液中的相对离子浓度有反应的一类带电聚合物表面活性剂和带电荷的pH指示剂，其电荷与带电聚合物表面活性剂的电荷相反。带电的聚合物表面活性剂可溶于大约或等于约1重量％（= 1重量％溶质）的水和低离子浓度= 0.1重量％的水溶液。％盐，但不溶于（<1重量％溶质）在高离子浓度> 0.1重量％的水溶液中。％盐。本发明还描述了结合这种测定装置的吸收制品以及使用这种测试形式监测尿样的脱水或测试离子强度的方法。

9. 发明申请

WO2012023071A2 DEHYDRATION SENSORS WITH ION-RESPONSIVE AND CHARGED POLYMERIC SURFACTANTS 审中-公开
标题翻译：具有离子反应和带电聚合物表面活性剂的脱水传感器
公开(公告)号：WO2012023071A2
公开(公告)日：2012-02-23
申请号：PCT/IB2011/053313
申请日：2011-07-25
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , SONG, Xuedong , WEI, Ning , PHILLIPS, Ronnie, L.
发明人： SONG, Xuedong , WEI, Ning , PHILLIPS, Ronnie, L.
IPC分类号： G01N33/493 , G01N33/52 , G01N21/80 , G01N31/22
CPC分类号： G01N33/558 , A61F13/42 , A61F13/84 , A61F2013/00429 , A61F2013/0094 , A61F2013/00948 , A61F2013/15081 , A61F2013/15154 , A61F2013/8473
摘要： A lateral flow assay device for determining the relative ionic strength of urine is described. The device includes a buffering zone having a polyelectrolyte disposed therein, and an indicator zone having a pH indicator non-diffusively immobilized therein, the indicator zone being separate from the buffering zone and positioned adjacent to and in fluid communication with the buffering zone. A detection zone is part of the buffering zone, and has a buffering component comprising a weak polymeric acid and weak polymeric base with a pKa ≤ 10 -3 , and a class of charged polymeric surfactants that are responsive to relative ion concentrations in a sample solution, and a charged pH indicator with a charge opposite to that of the charged polymeric surfactant. The charged polymeric surfactant is soluble in amounts of greater than or equal to about 1% by weight (≥ 1wt. % solute) in water and aqueous solutions of low ionic concentration of ≤ 0.1 wt. % salts, but insoluble ( 0.1 wt. % salts. The present invention also describes absorbent articles incorporating such an assay device and methods of monitoring dehydration or testing ion strength of a urine sample using such a test format.
摘要翻译：描述了用于确定尿液的相对离子强度的侧流测定装置。该装置包括其中设置有聚电解质的缓冲区和具有非扩散固定在其中的指示剂区的指示剂区，指示剂区与缓冲区分开并且与缓冲区相邻并且与缓冲区流体连通。检测区是缓冲区的一部分，并且具有包含弱聚合酸和弱聚合物碱的缓冲组分，所述缓冲组分具有pKa≤10-3和一类带电聚合物表面活性剂，其对样品溶液中的相对离子浓度，以及与带电聚合物表面活性剂的电荷相反的带电荷pH指示剂。带电聚合物表面活性剂在水中的溶解度大于或等于约1重量％（≥1重量％溶质），并且低离子浓度的水溶液≤0.1重量％％的盐，但是在高离子浓度的水溶液中不溶（<1wt。％溶质） 0.1重量％％的盐。本发明还描述了包含这种测定装置的吸收制品和使用这种测试形式来监测尿样的脱水或测试离子强度的方法。

10. 发明申请

WO2010048484A2 OPTICAL SPECTRAL CONCENTRATOR, SENSORS AND OPTICAL ENERGY POWER SYSTEMS 审中-公开
标题翻译：光谱集中器，传感器和光学能量系统
公开(公告)号：WO2010048484A2
公开(公告)日：2010-04-29
申请号：PCT/US2009061795
申请日：2009-10-23
申请人： UNIV CALIFORNIA , YU PAUL KIT LAI , CHEN WINNIE VICTORIA WEI-NING
发明人： YU PAUL KIT LAI , CHEN WINNIE VICTORIA WEI-NING
IPC分类号： F24S23/00 , F24S23/30 , H01L31/042
CPC分类号： H01L31/055 , F24J2/08 , H01S5/041 , H01S5/50 , Y02B10/20 , Y02E10/52
摘要： Methods and devices of the invention perform an optical concentration by an expansion of usable spectral width of the incident energy. Preferred methods and devices of the invention concentrate optical energy by tuning it into a narrow spectral width to match the bandgap of another system component, such as an optical fiber, an optical sensor or a photovoltaic device that converts the optical energy. Embodiments of the invention include methods and devices for the spectral concentration of multi-wavelength light and subsequent transport of the concentrated output light.
摘要翻译：本发明的方法和装置通过扩大入射能量的可用光谱宽度来执行光学浓度。本发明的优选方法和装置通过将光能调谐到窄的光谱宽度来集中光能，以匹配另一个系统部件（例如光纤，光学传感器或转换光能的光伏装置）的带隙。本发明的实施例包括用于多波长光的光谱浓度以及随后输送集中的输出光的方法和设备。

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