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1. 发明公开

US20240261862A1 ADDITIVE MANUFACTURING PROCESS AND PRODUCT OBTAINABLE THROUGH THE PROCESS 审中-公开
公开(公告)号：US20240261862A1
公开(公告)日：2024-08-08
申请号：US18565858
申请日：2022-06-09
申请人： POLITECNICO DI TORINO , UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Manuela Galati , Elena Bassoli , Andrea Gatto , Luca Iuliano
IPC分类号： B22F10/38 , B22F10/28 , B22F10/85 , B33Y10/00 , B33Y50/02 , B33Y80/00
CPC分类号： B22F10/38 , B22F10/28 , B22F10/85 , B33Y10/00 , B33Y50/02 , B33Y80/00
摘要： An additive manufacturing process for manufacturing a solid body designed to be delimited by a predefined outer surface includes selecting at least one volume portion of the solid body, preparing a three-dimensional model of the solid body by means of a computer, in which the selected volume portion is modelled independently of the rest of the solid body, supplying the model in a suitable data interface format to the processing unit of an additive manufacturing machine, and operating the additive manufacturing machine for producing the solid body according to the model, thus obtaining the predefined outer surface.

2. 发明申请

US20230011201A1 COMPOSITE MATERIAL COMPOSED OF A BIO-FILLER AND A THERMOPLASTIC MATRIX AND PROCESS FOR MAKING AN ARTICLE WITH SUCH COMPOSITE MATERIAL 有权
公开(公告)号：US20230011201A1
公开(公告)日：2023-01-12
申请号：US17778991
申请日：2020-11-19
申请人： UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Alessandro NANNI , Massimo MESSORI
IPC分类号： C08K11/00 , B29C64/118 , B29C64/153 , B33Y10/00 , B33Y70/00 , B33Y80/00
摘要： A composite material consisting of a bio-filler and a thermoplastic matrix is described. The bio-filler derives from the lees taken as solid/liquid residue from the bottom of containers containing wine or must, after fermentation, during storage or after any other treatment of wine or must, as well as after filtration, centrifugation or after any process of separation of wine or must. A process for obtaining such a bio-filler and three processes for obtaining an article with such a composite material is also described.

3. 发明公开

US20240109830A1 CANNABIS EXTRACTS AND USES THEREOF 审中-公开
公开(公告)号：US20240109830A1
公开(公告)日：2024-04-04
申请号：US18516260
申请日：2023-11-21
申请人： CONSIGLIO NAZIONALE DELLE RICERCHE , Universita' degli Studi di Modena e Reggio Emilia , SAPIENZA UNIVERSITÀ DI ROMA
发明人： Pasquale Linciano , Cinzia Citti , Fabiana Russo , Livio Luongo , Monica Iannotta , Carmela Belardo , Sabatino Maione , Maria Angela Vandelli , Flavio Forni , Giuseppe Gigli , Aldo Laganá , Anna Laura Capriotti , Carmela Maria Montone , Giuseppe Cannazza
IPC分类号： C07C37/11 , C07C39/23 , C07D311/80
CPC分类号： C07C37/11 , C07C39/23 , C07D311/80
摘要： The present disclosure concerns a group of cannabinoid compounds defined by formulas (I) to (IV), wherein R1 is —H or —COOH, for the first time isolated and fully characterized in structure, absolute stereochemistry by the present applicant. Methods of isolation, characterization, stereoselective synthesis, biological activity, pharmaceutical composition and therapeutic applications of the present compounds as modulators of the cannabinoid CB1 receptor are also object of the disclosure.

4. 发明公开

US20240000997A1 USE OF SCLERAL OSSICLES INTEGRATED IN 3D RETICLES FOR THE RECOVERY OF BONE INJURIES OF CRITICAL SIZE IN THE HEALTHCARE AND VETERINARY SECTOR 审中-公开
公开(公告)号：US20240000997A1
公开(公告)日：2024-01-04
申请号：US18036368
申请日：2021-11-04
申请人： UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Carla Palumbo
IPC分类号： A61L27/36
CPC分类号： A61L27/3608 , A61L2430/02
摘要： Scleral ossicles (OS) are described, integrated in 3D lattices, to be used as a naturally decellularized material for the regeneration of at least a portion of a bone system, in the veterinary and healthcare fields.

5. 发明申请

US20200291353A1 METHOD FOR PRODUCING CELL FLAPS 审中-公开
公开(公告)号：US20200291353A1
公开(公告)日：2020-09-17
申请号：US16639955
申请日：2018-08-10
申请人： HOLOSTEM TERAPIE AVANZATE S.R.L. , UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Michele DE LUCA , Graziella PELLEGRINI , Andrea ALESSANDRINI
IPC分类号： C12N5/071 , C12N15/86
摘要： The present invention refers to an in vitro method for producing a flap of genetically modified cells on fibrin substrate and to the flap so obtained.

6. 发明授权

US09371337B2 β-lactamase inhibitors 有权
标题翻译： β-内酰胺酶抑制剂
公开(公告)号：US09371337B2
公开(公告)日：2016-06-21
申请号：US14252347
申请日：2014-04-14
申请人： The Regents of the University of California , Universita' Degli Studi di Modena e Reggio Emilia
发明人： Brian K. Shoichet , Fabio Prati , Emilia Caselli , Chiara Romagnoli , Oliv Eidam
IPC分类号： C07F5/02 , A61K45/06 , A61K31/43 , A61K31/431
CPC分类号： C07F5/025 , A61K31/43 , A61K31/431 , A61K45/06 , Y02A50/401 , Y02A50/402 , Y02A50/406 , Y02A50/469 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/479 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
摘要翻译：本文公开的是含硼化合物和用于治疗与抗生素抗性微生物有关的感染的方法。

7. 发明公开

US20240052909A1 AXIAL DAMPING DEVICE WITH ELASTOMERS 审中-公开
公开(公告)号：US20240052909A1
公开(公告)日：2024-02-15
申请号：US18036340
申请日：2021-11-04
申请人： UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Federico Oyedeji , Matteo Pelliciari , Luca Lanzoni , Angelo Marcello Tarantino , Enrico Salardi
IPC分类号： F16F15/08
CPC分类号： F16F15/08 , F16F2224/025
摘要： A device (5, 20) is described for isolating and damping uniaxial vibrations to be interposed between rigid elements (2, 3) in relative motion, comprising damping and insulating means (15) in elastomeric material, suitable for performing this function of insulation and damping through repeated deformations and consequent hysteresis of the elastomeric material; the device (5, 20) comprises: a first head (11); at least two sleeves (11a) integral with the first head (11); a second head (12); at least two bars (13) which are inserted at a first end in the sleeves (11a) and are connected at a second end with the second head (12); at least one stabilizing jacket (14); and an elastic element (15) which is interposed between the first head (11) and the second head (12), reacting to compression when, due to the application of the load, the damper device (5, 20) is shortened.

8. 发明公开

US20230255893A1 FORMULATION TO DELIVER LIPOPHILIC ACTIVE INGREDIENTS 审中-公开
公开(公告)号：US20230255893A1
公开(公告)日：2023-08-17
申请号：US18011639
申请日：2021-07-07
申请人： PERFORMS S.R.L. , UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Eleonora Maretti , Eliana Grazia Leo , Virginia Brighenti
IPC分类号： A61K9/51 , A61K31/232 , A61K31/164 , A61K9/00 , A61P17/06
CPC分类号： A61K9/5192 , A61K9/5123 , A61K31/232 , A61K31/164 , A61K9/0014 , A61P17/06
摘要： The present invention relates to a technological platform for the delivery of lipophilic active ingredients.

9. 发明申请

US20150347940A1 SELECTION OF OPTIMUM SERVICE PROVIDERS UNDER UNCERTAINTY 审中-公开
标题翻译：选择不确定的最佳服务提供商
公开(公告)号：US20150347940A1
公开(公告)日：2015-12-03
申请号：US14287243
申请日：2014-05-27
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Yurdaer N. DOGANATA , Asser TANTAWI , Stefania TOSI , Merve UNUVAR
IPC分类号： G06Q10/06
CPC分类号： G06Q10/06311
摘要： Various embodiments select at least one service provider from a plurality of service providers in a computing environment. In one embodiment, a service request is received from a user. The service request comprises at least a set of service requirements to be satisfied by at least one service provider. A satisfaction level is predicted for each of a plurality of service providers with respect to each of the set of service requirements. The prediction is based on a prediction satisfaction model associated with each of the plurality of service providers. A probability of an actual observed satisfaction level being higher than at least a user defined threshold is calculated for each of the predicted satisfaction levels. At least one service provider is selected from the plurality of service providers for satisfying the service request based on the probability that has been calculated for each satisfaction level predicted.
摘要翻译：各种实施例在计算环境中从多个服务提供商中选择至少一个服务提供商。在一个实施例中，从用户接收服务请求。服务请求至少包括一组要由至少一个服务提供商满足的服务要求。对于多个服务提供商中的每个服务提供商，针对服务要求中的每一个来预测满意程度。该预测基于与多个服务提供商中的每一个相关联的预测满意度模型。针对每个预测的满意度级别计算实际观察到的满意度高于至少一个用户定义的阈值的概率。从多个服务提供者中选择至少一个服务提供商，以便基于为预测的每个满意度计算的概率来满足服务请求。

10. 发明申请

US20210260037A1 MELANOCORTIN AGENTS FOR USE IN THE THERAPEUTIC TREATMENT OF MELANOMA, TUMORS OF THE GASTROINTESTINAL TRACT, AND THYROID CARCINOMA 有权
公开(公告)号：US20210260037A1
公开(公告)日：2021-08-26
申请号：US17253883
申请日：2019-06-14
申请人： UNIVERSITA' DI PISA , UNIVERSITA' DEGLI STUDI DI MODENA E REGGIO EMILIA
发明人： Guido BOCCI , Teresa DI DESIDERO , Daniela GIULIANI , Salvatore GUARINI , Paola ORLANDI , Alessandra OTTANI , Carla Maria Francesca PARDINI , Francesca VAGLINI
IPC分类号： A61K31/4164 , A61K45/06 , A61K31/437 , A61P35/00
摘要： A method of therapeutic treatment of a tumor pathology including melanoma, tumors of the gastrointestinal tract, and/or thyroid carcinoma by administering to a subject in need thereof melanocortin receptor-4 (MC4R) antagonists is provided. The melanocortin receptor-4 antagonists are suitable in a targeted anti-tumor treatment, and particularly in an adjuvant therapy or in a therapy affecting onset and/or progression of tumor metastasis. A pharmaceutical composition including a melanocortin receptor-4 (MC4R) antagonist in a pharmaceutically acceptable vehicle, and in combination with optional adjuvants, stabilizers and/or preservatives, is also provided.

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