专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20140186941A1 CELL CULTURE VESSEL, AND CULTURE DEVICE EQUIPPED WITH SAME 有权
标题翻译：细胞培养皿和装备有其的培养装置
公开(公告)号：US20140186941A1
公开(公告)日：2014-07-03
申请号：US14124754
申请日：2012-06-05
申请人： Guangbin Zhou , Taizo Miyazaki , Ryota Nakajima , Toyoshige Kobayashi , Shizu Matsuoka
发明人： Guangbin Zhou , Taizo Miyazaki , Ryota Nakajima , Toyoshige Kobayashi , Shizu Matsuoka
IPC分类号： C12M1/00
CPC分类号： C12M47/04 , C12M23/20 , C12M25/08 , C12M33/00 , C12M35/02 , C12M41/36 , C12M47/02
摘要： Disclosed is a cell culture vessel of the present invention, which is composed of a space enclosed by a housing that supports a medium and a cell attachment part, disposed on the bottom surface of the space, that attaches and supports the cells, the cell attachment part having a cell immobilizing mechanism that guides the cells in the space to the cell attachment part to immobilize there and a cell detachment mechanism that detaches the cells attached in the cell attachment part, the cell immobilizing mechanism having a step of applying a voltage to an electrode disposed in the cell attachment part to generate a heterogeneous electric field in the space, and the cell detachment mechanism having a step of applying a voltage to an electrode disposed in the cell attachment part to induce electrolyte in the space.
摘要翻译：公开了本发明的细胞培养容器，其由由支撑培养基的壳体包围的空间和设置在空间的底面上的细胞附着部分构成，其附着并支撑细胞，细胞附着物具有细胞固定机构的部分，其将空间中的细胞引导到细胞附着部分以固定在其上，以及细胞分离机构，其分离附着在细胞附着部分中的细胞，细胞固定机构具有向电极，其设置在电池安装部中，以在该空间中产生异质电场，并且电池拆卸机构具有向设置在电池安装部中的电极施加电压以在该空间中诱导电解质的步骤。

2. 发明申请

US20140087455A1 Cell Culture Device and Transport Device 有权
标题翻译：细胞培养装置和运输装置
公开(公告)号：US20140087455A1
公开(公告)日：2014-03-27
申请号：US14111060
申请日：2012-04-04
申请人： Toyoshige Kobayashi , Ryota Nakajima , Takayuki Nozaki , Shizu Matsuoka
发明人： Toyoshige Kobayashi , Ryota Nakajima , Takayuki Nozaki , Shizu Matsuoka
IPC分类号： C12M1/00
CPC分类号： C12M29/00 , C12M23/14 , C12M23/50 , C12M37/00 , C12M41/14
摘要： The present invention provides a carrier device including a culture vessel and a flow channel, which have a closed structure, for supplying cell liquid or a culture medium into the flow channel; and a method of aseptically injecting liquid, such as the cell or the culture medium, into the culture vessel and the flow channel. The present invention provides a carrier jig 19 including a drive base 27, a culture vessel base 21 that holds a culture vessel 20, a culture medium base 32 that holds a cell bag 60 and the like for the culture medium and the cell, and a detachable flow channel 40, those of which are held by a lift 98 to be carried to a cell culture device. A part of the flow channel 40 and the cell bag 60 mounted on the carrier jig 19 are put into a clean space 78. The cell and the culture medium are supplied into the flow channel 40 by using the cell bag 60 and other bags in the clean space, and then, an injection port 89 is closed. The respective bases and the flow channel are simultaneously mounted to the cell culture device by using the carrier jig 19. Thus, the aseptic cell culture can be realized.
摘要翻译：本发明提供了一种载体装置，其包括具有封闭结构的培养容器和流动通道，用于将细胞液或培养基供给到流路中; 以及将诸如细胞或培养基的液体无菌注入培养容器和流路的方法。本发明提供一种载体夹具19，其包括驱动基座27，保持培养容器20的培养容器基座21，保持培养基和细胞的细胞袋60等的培养基底32，以及可拆卸的流动通道40，其中的流动通道由电梯98保持以运送到细胞培养装置。将流路40的一部分和安装在载体夹具19上的电池袋60放入清洁空间78中。电池和培养基通过使用电池袋60和其他袋子供应到流路40中清洁空间，然后关闭注入口89。通过使用载体夹具19将各基底和流路同时安装在细胞培养装置上。因此，可以实现无菌细胞培养。

3. 发明授权

US08206976B2 Culture system, culture apparatus, culture vessel box, and air cleaning method 有权
标题翻译：培养体系，培养装置，养殖箱，空气净化方法等
公开(公告)号：US08206976B2
公开(公告)日：2012-06-26
申请号：US11756015
申请日：2007-05-31
申请人： Toyoshige Kobayashi , Kazutoshi Kan
发明人： Toyoshige Kobayashi , Kazutoshi Kan
IPC分类号： C12M1/00 , C12M3/00 , C12M1/22
CPC分类号： C12M41/14 , C12M23/50 , C12M41/34 , Y10S435/809
摘要： The present invention enables to keep the culture vessel clean with the clean air without touching the open air in which floating bacteria exist, and to culture cells with taking in and out the culture apparatus under the environment with low damages for the cells in constant temperature. The present invention is the culture vessel box which has one or more culture vessels, has the heater, and has the door outside which the good adhesive resin film is stuck, the culture apparatus which has various apparatuses including a heater and culture cells, and has the door outside which the resin film is stuck similarly to the culture vessel box and has its storing chamber. So, it is characterized in that the culture vessel box and the culture apparatus are connected with keeping an interior of the culture vessel box, including a culture vessel, and the interior of the culture apparatus in the clean state and constant temperature by sticking mutual doors of the culture vessel box and culture apparatus at the time of connection to confine the dirty portion which touched on open air by adhesiveness of their resin films, and moving the doors to the door storing chamber integrally.
摘要翻译：本发明能够在没有接触浮游细菌存在的露天的情况下保持培养容器清洁，并且在环境下以恒定温度对细胞的低损伤进入和移出培养装置的培养细胞。本发明是一种具有一个或多个培养容器，具有加热器并且具有粘合树脂薄膜的门外部的培养容器盒，具有包括加热器和培养细胞在内的各种装置的培养装置，与培养容器盒相似的树脂膜的外侧的门具有其存放室。因此，其特征在于，将培养容器箱和培养装置与包含培养容器的培养容器箱的内部和培养装置的内部连接，并且通过粘合相互的门将培养装置的内部保持在清洁状态和恒定温度的培养容器盒和培养装置，通过它们的树脂膜的粘合性来限制接触露天的脏部分，并将门一体地移动到门储存室。

4. 发明申请

US20080145924A1 Cell culture apparatus and control method thereof 有权
标题翻译：细胞培养装置及其控制方法
公开(公告)号：US20080145924A1
公开(公告)日：2008-06-19
申请号：US11984160
申请日：2007-11-14
申请人： Toyoshige Kobayashi , Kazutoshi Kan
发明人： Toyoshige Kobayashi , Kazutoshi Kan
IPC分类号： C12M1/00
CPC分类号： C12M23/14 , B01L3/50853 , B01L3/50855 , B01L2200/025 , B01L2200/026 , B01L2300/046 , C12M23/34 , C12M23/42 , C12M23/48 , C12M23/50
摘要： A cell culture apparatus is provided in which a plurality of culture vessels can be mounted and removed in a set, which has a regulation mechanism that can fix each culture vessel in the correct position, and which enables suppression of production costs. The cell culture apparatus has one or a plurality of concave portions, and can arrange and accommodate one or a plurality of culture vessels in the concave portions. Spring-type fixing devices are provided in the depth direction and the width direction, respectively, in each concave portion. The two spring-type fixing devices press against side surfaces of the culture vessel to fix the culture vessel in the culture vessel set. At this time, by pressing against the culture vessel at two points, the position of the culture vessel at the time of fixing can be maintained with good accuracy.
摘要翻译：提供一种细胞培养装置，其中可以将一组培养容器安装和移除，该组具有可将每个培养容器固定在正确位置的调节机构，并且能够抑制生产成本。细胞培养装置具有一个或多个凹部，并且可以在凹部中布置并容纳一个或多个培养容器。分别在各个凹部中沿深度方向和宽度方向设置弹簧式固定装置。两个弹簧式固定装置压靠培养容器的侧表面，将培养容器固定在培养容器组中。此时，通过在两点压迫培养容器，能够以良好的精度维持定影时的培养容器的位置。

5. 发明授权

US09487747B2 Cell culture device 有权
标题翻译：细胞培养装置
公开(公告)号：US09487747B2
公开(公告)日：2016-11-08
申请号：US14124754
申请日：2012-06-05
申请人： Guangbin Zhou , Taizo Miyazaki , Ryota Nakajima , Toyoshige Kobayashi , Shizu Matsuoka
发明人： Guangbin Zhou , Taizo Miyazaki , Ryota Nakajima , Toyoshige Kobayashi , Shizu Matsuoka
IPC分类号： C12M3/00 , C12M1/00 , C12M1/42 , C12M1/12 , C12M1/26 , C12M1/34
CPC分类号： C12M47/04 , C12M23/20 , C12M25/08 , C12M33/00 , C12M35/02 , C12M41/36 , C12M47/02
摘要： Disclosed is a cell culture vessel of the present invention, which is composed of a space enclosed by a housing that supports a medium and a cell attachment part, disposed on the bottom surface of the space, that attaches and supports the cells, the cell attachment part having a cell immobilizing mechanism that guides the cells in the space to the cell attachment part to immobilize there and a cell detachment mechanism that detaches the cells attached in the cell attachment part, the cell immobilizing mechanism having a step of applying a voltage to an electrode disposed in the cell attachment part to generate a heterogeneous electric field in the space, and the cell detachment mechanism having a step of applying a voltage to an electrode disposed in the cell attachment part to induce electrolyte in the space.
摘要翻译：公开了本发明的细胞培养容器，其由由支撑培养基的壳体包围的空间和设置在空间的底面上的细胞附着部分构成，其附着并支撑细胞，细胞附着物具有细胞固定机构的部分，其将空间中的细胞引导到细胞附着部分以固定在其上，以及细胞分离机构，其分离附着在细胞附着部分中的细胞，细胞固定机构具有向电极，其设置在电池安装部中，以在该空间中产生异质电场，并且电池拆卸机构具有向设置在电池安装部中的电极施加电压以在该空间中诱导电解质的步骤。

6. 发明申请

US20140141499A1 Cell Culture Device and Cell Culture Method 审中-公开
标题翻译：细胞培养装置和细胞培养方法
公开(公告)号：US20140141499A1
公开(公告)日：2014-05-22
申请号：US14129122
申请日：2012-06-25
申请人： Ryota Nakajima , Shizu Matsuoka , Toyoshige Kobayashi
发明人： Ryota Nakajima , Shizu Matsuoka , Toyoshige Kobayashi
IPC分类号： C12M1/34
CPC分类号： C12M41/46 , C12M21/08 , C12M41/34 , C12M41/36
摘要： Provided is a cell culture device having a culture area for culturing the stem or progenitor cells, from which tissues are formed. The cell culture device includes an oxygen adjusting part that adjusts the oxygen supply in the culture area, a controller that controls the oxygen adjusting part, and another controller that controls a first oxygen supply during a first period of the period, in which the stem cells and the progenitor cells differentiate; and a second oxygen supply greater in amount than the first supply during a second period, during which the stem cells and the progenitor cells differentiate, out of the whole culture period, and that controls the oxygen adjusting part based on the growth progress of the stem cells and the progenitor cells through self-replication to change the first oxygen supply to the second oxygen supply.
摘要翻译：本发明提供一种细胞培养装置，其具有用于培养形成组织的茎或祖细胞的培养区域。细胞培养装置包括调节培养区域中的氧供给的氧调节部，控制氧调节部的控制器，以及控制在第一期间的第一氧供给的控制器，其中，干细胞祖细胞分化; 以及在整个培养期间干细胞和祖细胞分化的第二时期期间比第一次供应量大的第二供氧量，并且基于茎的生长进程来控制氧调节部分细胞和祖细胞通过自我复制将第一氧气供应改变为第二氧气供应。

7. 发明授权

US07749750B2 Culturing apparatus 有权
标题翻译：培养装置
公开(公告)号：US07749750B2
公开(公告)日：2010-07-06
申请号：US11192023
申请日：2005-07-29
申请人： Toyoshige Kobayashi , Kazutoshi Kan , Akira Koide , Hideaki Sakai
发明人： Toyoshige Kobayashi , Kazutoshi Kan , Akira Koide , Hideaki Sakai
IPC分类号： C12M1/22 , C12M3/00
CPC分类号： C12M27/02 , C12M23/04 , C12M23/46 , C12M29/10
摘要： A culturing apparatus has a culture vessel having a first elastic seal bonded on its upper surface and a culture space formed thereon, and a joint for supplying solution such as a medium to the culture vessel and a second elastic seal having microprojection formed at the lower face. The first elastic seal has a valve for supplying or discharging solution. The second elastic seal is formed with microprojection at the position corresponding to a valve for preventing a spill. The culture vessel and the joint are sucked between the first elastic seal and the second elastic seal, thereby forming an integral seeding device.
摘要翻译：培养装置具有培养容器，其具有在其上表面上形成的第一弹性密封件和形成在其上的培养空间，以及用于向培养容器供应诸如培养基的溶液的接头和形成在下表面的微突起的第二弹性密封件。第一弹性密封件具有用于供应或排出溶液的阀。第二弹性密封件在对应于用于防止溢出的阀的位置处由微喷射体形成。培养容器和接头被吸入第一弹性密封件和第二弹性密封件之间，从而形成整体的种子装置。

8. 发明授权

US09951305B2 Cell culture device and transport device 有权
公开(公告)号：US09951305B2
公开(公告)日：2018-04-24
申请号：US14111060
申请日：2012-04-04
申请人： Toyoshige Kobayashi , Ryota Nakajima , Takayuki Nozaki , Shizu Matsuoka
发明人： Toyoshige Kobayashi , Ryota Nakajima , Takayuki Nozaki , Shizu Matsuoka
IPC分类号： C12M1/00 , C12M1/12
CPC分类号： C12M29/00 , C12M23/14 , C12M23/50 , C12M37/00 , C12M41/14
摘要： The present invention provides a carrier device including a culture vessel and a flow channel, which have a closed structure, for supplying cell liquid or a culture medium into the flow channel; and a method of aseptically injecting liquid, such as the cell or the culture medium, into the culture vessel and the flow channel. The present invention provides a carrier jig 19 including a drive base 27, a culture vessel base 21 that holds a culture vessel 20, a culture medium base 32 that holds a cell bag 60 and the like for the culture medium and the cell, and a detachable flow channel 40, those of which are held by a lift 98 to be carried to a cell culture device. A part of the flow channel 40 and the cell bag 60 mounted on the carrier jig 19 are put into a clean space 78. The cell and the culture medium are supplied into the flow channel 40 by using the cell bag 60 and other bags in the clean space, and then, an injection port 89 is closed. The respective bases and the flow channel are simultaneously mounted to the cell culture device by using the carrier jig 19. Thus, the aseptic cell culture can be realized.

9. 发明申请

US20150072401A1 CULTURE VESSEL AND AUTOMATED CULTURE APPARATUS 审中-公开
标题翻译：文化船和自动文化设备
公开(公告)号：US20150072401A1
公开(公告)日：2015-03-12
申请号：US14381659
申请日：2012-03-29
申请人： Takayuki Nozaki , Guangbin Zhou , Ryota Nakajima , Shizu Matsuoka , Toyoshige Kobayashi , Naoko Senda
发明人： Takayuki Nozaki , Guangbin Zhou , Ryota Nakajima , Shizu Matsuoka , Toyoshige Kobayashi , Naoko Senda
IPC分类号： C12M1/36 , C12M1/00 , C12M3/00 , C12M1/12
CPC分类号： C12M41/48 , C12M21/08 , C12M23/44 , C12M25/04 , C12M29/10 , C12M37/00
摘要： In a closed system culture vessel to be used in an automated culture apparatus, some of the ports perform both liquid supply and gas supply functions. Culture medium is thereby made to flow always in one direction. The culture vessel is also configured so that, in the complete culture medium exchange process and the effluent recovery process for analyzing culture medium components, waste liquid medium does not get mixed into fresh culture medium.
摘要翻译：在用于自动培养装置的封闭系统培养容器中，一些端口同时执行液体供应和气体供应功能。由此使培养基始终沿一个方向流动。培养容器也配置成使得在完全培养基的交换过程和用于分析培养基成分的废水回收过程中，废液介质不会混入新鲜培养基中。

10. 发明授权

US08883492B2 Cell culture apparatus 有权
标题翻译：细胞培养装置
公开(公告)号：US08883492B2
公开(公告)日：2014-11-11
申请号：US13331237
申请日：2011-12-20
申请人： Toyoshige Kobayashi , Ryota Nakajima , Takayuki Nozaki , Shizu Matsuoka
发明人： Toyoshige Kobayashi , Ryota Nakajima , Takayuki Nozaki , Shizu Matsuoka
IPC分类号： C12M1/00 , C12M1/34 , C12M3/00
CPC分类号： C12M41/14
摘要： A cell culture apparatus has four sections, including a cell culture chamber, refrigerator, control unit, and intermediate chamber. The cell culture chamber includes a culture vessel base as a holding member for holding and installing a culture vessel, a microscope for photographing a cell image within the culture vessel, and a drive base which has drive mechanisms such as a pump and a valve to be connected to a flow channel having a closed structure including a tank. With the drive base within the cell culture chamber as the center, the rotatable culture vessel is arranged in the horizontal direction and the refrigerator in which the culture medium base containing the cell fluid and culture medium is installed is arranged in the vertical direction. The arrangement configuration is space-saving and provides a short distance between the instruments.
摘要翻译：细胞培养装置具有四个部分，包括细胞培养室，冰箱，控制单元和中间室。细胞培养室包括培养容器底座作为用于保持和安装培养容器的保持构件，用于拍摄培养容器内的细胞图像的显微镜和具有诸如泵和阀的驱动机构的驱动基座连接到具有包括罐的封闭结构的流动通道。以细胞培养室内的驱动基座为中心，沿水平方向布置可旋转的培养容器，并且在垂直方向上布置有包含细胞液和培养基的培养基的冰箱。排列配置节省空间并且在仪器之间提供短距离。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式