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1. 发明申请

US20110162117A1 DEVICE FOR SCANNING A SAMPLE SURFACE COVERED WITH A LIQUID 失效
标题翻译：用于扫描包含液体的样品表面的装置
公开(公告)号：US20110162117A1
公开(公告)日：2011-06-30
申请号：US12441267
申请日：2007-09-14
申请人： Tilman Schäffer , Matthias Böcker , Boris Anczykowski
发明人： Tilman Schäffer , Matthias Böcker , Boris Anczykowski
IPC分类号： G01Q20/02
CPC分类号： G01Q30/14 , G01Q20/02 , G01Q60/22 , G01Q60/44
摘要： A device for scanning the surface of a sample which is covered with a liquid, comprising a probe which has a tip at one end, means for moving the probe and the sample relative to one another a light source focussing device which focuses light from the light source onto a location in the area of the tip located in the liquid and a detector for detecting light which was scattered by the tip, wherein a boundary surface at which the light enters the liquid is located on the light path between the light source and the tip, wherein the boundary surface is positionally fixed with respect to the probe.
摘要翻译：一种用于扫描被液体覆盖的样品的表面的装置，包括在一端具有尖端的探针，用于相对于彼此移动探针和样品的装置，用于聚焦来自光的光源聚焦装置源到位于液体中的尖端区域中的位置和用于检测由尖端散射的光的检测器，其中光进入液体的边界面位于光源和光源之间的光路上尖端，其中所述边界表面相对于所述探针位置固定。

2. 发明授权

US06455838B2 High sensitivity deflection sensing device 失效
标题翻译：高灵敏度偏转感测装置
公开(公告)号：US06455838B2
公开(公告)日：2002-09-24
申请号：US09166979
申请日：1998-10-06
申请人： Tilman Schäffer , Paul K. Hansma
发明人： Tilman Schäffer , Paul K. Hansma
IPC分类号： H01J314
CPC分类号： G01Q20/02 , G01Q70/06 , Y10S977/863 , Y10S977/869 , Y10S977/87
摘要： A high sensitivity beam deflection sensing optical device, such as an atomic force microscope, including one or more of the following: specified means in the path of the incident beam for adjusting the size and/or power of the incident beam spot, means for moving the incident beam spot with movement of the object whereby to maintain the position of the spot on the object, and means for increasing the signal to noise ratio of the optical detector in which adjusted gains are applied to different segments of the optical detector.
摘要翻译：一种高灵敏度光束偏转感测光学装置，例如原子力显微镜，包括以下中的一个或多个：用于调整入射光束光斑的尺寸和/或功率的入射光束的路径中的指定装置，用于移动的装置具有物体运动的入射光束点，从而保持物体上的光斑的位置，以及用于增加光学检测器的信噪比的装置，其中调节的增益被施加到光学检测器的不同部分。

3. 发明授权

US08332960B2 Device for scanning a sample surface covered with a liquid 失效
标题翻译：用于扫描被液体覆盖的样品表面的装置
公开(公告)号：US08332960B2
公开(公告)日：2012-12-11
申请号：US12441267
申请日：2007-09-14
申请人： Tilman Schäffer , Matthias Böcker , Boris Anczykowski
发明人： Tilman Schäffer , Matthias Böcker , Boris Anczykowski
IPC分类号： G01Q60/18
CPC分类号： G01Q30/14 , G01Q20/02 , G01Q60/22 , G01Q60/44
摘要： A device for scanning the surface of a sample which is covered with a liquid, comprising a probe which has a tip at one end, means for moving the probe and the sample relative to one another a light source focussing device which focuses light from the light source onto a location in the area of the tip located in the liquid and a detector for detecting light which was scattered by the tip, wherein a boundary surface at which the light enters the liquid is located on the light path between the light source and the tip, wherein the boundary surface is positionally fixed with respect to the probe.
摘要翻译：一种用于扫描被液体覆盖的样品的表面的装置，包括在一端具有尖端的探针，用于相对于彼此移动探针和样品的装置，用于聚焦来自光的光源聚焦装置源到位于液体中的尖端区域中的位置和用于检测由尖端散射的光的检测器，其中光进入液体的边界面位于光源和光源之间的光路上尖端，其中所述边界表面相对于所述探针位置固定。

4. 发明申请

US20090205960A1 DEVICE AND METHOD FOR DETECTING ARTICLES WITH PIPETTE AND NANOPORE 审中-公开
标题翻译：用管和纳米级检测物品的装置和方法
公开(公告)号：US20090205960A1
公开(公告)日：2009-08-20
申请号：US12375099
申请日：2007-07-06
申请人： Tilman Schäffer , Harald Fuchs
发明人： Tilman Schäffer , Harald Fuchs
IPC分类号： G01N27/26 , G01N15/00
CPC分类号： G01N33/48721
摘要： A device and a method for detecting and/or characterizing particles are shown. The device includes at least one nanopore, a voltage source for generating an electric potential difference between the two sides of the at least one nanopore in order to generate an ion current through the nanopore when the nanopore is surrounded by an electrolyte, and a measuring instrument adapted for recording a change in the impedance of the at least one nanopore in respect of the ion current when one or more particles that are to be detected and are present in the electrolyte pass(es) through the at least one nanopore. The device also includes a pipette with an end portion in which an opening is formed. A flow of the particles that are to be detected from outside the pipette is generated through the opening and through the nanopore, and the pipette is moved relative to a sample.
摘要翻译：示出了用于检测和/或表征颗粒的装置和方法。所述装置包括至少一个纳米孔，用于在所述至少一个纳米孔的两侧之间产生电位差的电压源，以便当所述纳米孔被电解质包围时产生通过所述纳米孔的离子电流;以及测量仪器适于当要被检测并且存在于电解质中的一个或多个颗粒通过至少一个纳米孔时记录关于离子电流的至少一个纳米孔的阻抗的变化。该装置还包括具有其中形成有开口的端部的移液管。通过开口和通过纳米孔产生待从移液管外部检测的颗粒的流动，移液管相对于样品移动。

5. 发明授权

US06649902B2 Summing the output of an array of optical detector segments in an atomic force microscope 失效
标题翻译：在原子力显微镜中对光学探测器段阵列的输出求和
公开(公告)号：US06649902B2
公开(公告)日：2003-11-18
申请号：US10165503
申请日：2002-06-07
申请人： Tilman Schäffer , Paul K. Hansma
发明人： Tilman Schäffer , Paul K. Hansma
IPC分类号： H01J516
CPC分类号： G01Q20/02 , G01Q70/06 , Y10S977/863 , Y10S977/869 , Y10S977/87
摘要： A high sensitivity beam deflection sensing optical device, such as an atomic force microscope, including one or more of the following: specified means in the path of the incident beam for adjusting the size and/or power of the incident beam spot, means for moving the incident beam spot with movement of the object whereby to maintain the position of the spot on the object, and means for increasing the signal to noise ratio of the optical detector in which adjusted gains are applied to different segments of the optical detector.
摘要翻译：一种高灵敏度光束偏转感测光学装置，例如原子力显微镜，包括以下中的一个或多个：用于调整入射光束光斑的尺寸和/或功率的入射光束的路径中的指定装置，用于移动的装置具有物体运动的入射光束点，从而保持物体上的光斑的位置，以及用于增加光学检测器的信噪比的装置，其中调节的增益被施加到光学检测器的不同部分。

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