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1. 发明专利

IL276594D0 Fap inhibitor 未知
公开(公告)号：IL276594D0
公开(公告)日：2020-09-30
申请号：IL27659420
申请日：2020-08-06
申请人： UNIV HEIDELBERG , UWE HABERKORN , ANASTASIA LOKTEV , THOMAS LINDNER , WALTER MIER , CLEMENS KRATOCHWIL , FREDENIK GIESEL
发明人： UWE HABERKORN , ANASTASIA LOKTEV , THOMAS LINDNER , WALTER MIER , CLEMENS KRATOCHWIL , FREDENIK GIESEL
IPC分类号： A61P35/00
摘要： The present invention relates to a compound of formula (I), a pharmaceutical composition comprising or consisting of said compound, a kit comprising or consisting of said compound or pharmaceutical composition and use of the compound or pharmaceutical composition in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP).

2. 发明申请

US20210381126A1 SUBSTRATES FOR III-NITRIDE EPITAXY 有权
公开(公告)号：US20210381126A1
公开(公告)日：2021-12-09
申请号：US17411851
申请日：2021-08-25
申请人： Victor Sizov , Karl-Heinz Stegemann , Ronny Mueller-Biedermann , Thomas Lindner
发明人： Victor Sizov , Karl-Heinz Stegemann , Ronny Mueller-Biedermann , Thomas Lindner
IPC分类号： C30B25/18 , C30B29/40 , H01L21/02
摘要： A wafer suitable for epitaxial growth of gallium nitride (GaN) in a Metal Oxide Chemical Vapor Deposition (MOCVD) process. The wafer includes a silicon substrate having a front side and a back side and an edge extending between the front side and the back side, the edge including a front bevel surface connected to the front side and a back bevel surface connected to the back side, wherein the silicon substrate comprises an oxygen denuded silicon layer surrounding a core. The wafer further includes a protection layer being a thermally grown silicon oxide (SiO2) layer substantially covering the front bevel surface and the back bevel surface of the edge, while leaving at least a central region of the front side of the silicon substrate exposed, for preventing meltback during the MOCVD process.

3. 发明授权

US08629224B2 Water-soluble or water-swellable polymers on the basis of salts of acryloyldimethyltaurine acid or the derivatives thereof, the production thereof and the use thereof as thickener, stabilizer and consistency agents 失效
标题翻译：基于丙烯酰基二甲基牛磺酸或其衍生物的盐的水溶性或水溶胀性聚合物，其制备及其作为增稠剂，稳定剂和稠度剂的用途
公开(公告)号：US08629224B2
公开(公告)日：2014-01-14
申请号：US12747727
申请日：2008-12-16
申请人： Matthias Loeffler , Thomas Lindner , Ute Back , Michael Hornung
发明人： Matthias Loeffler , Thomas Lindner , Ute Back , Michael Hornung
IPC分类号： A61K8/81 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08
CPC分类号： A61Q19/08 , A61K8/8158 , A61Q5/006 , A61Q5/06 , A61Q17/04 , A61Q19/007 , A61Q19/02 , A61Q19/10 , C08F220/58 , C08F226/10 , C08F228/02 , C08F2220/585 , C08F2222/1026
摘要： Polymers are described comprising a) one or more of the recurring structural units of the formula (1) where R1 is hydrogen, methyl or ethyl and A is C1-C8 alkylene, and Q+ is H+, NH4+, Li+, Na+, K+, ½ Ca++, ½ Mg++, ½ Zn++ or ⅓ Al+++, and the neutralization degree of the structural units of formula (1) is 50 to 100 mol-%, and b) one or more of the recurring structural units of the formula (2) where R1 and A are R1 and A from formula (1) and X+ is [HNR5R6R7]+, where R5, R6 and R7 can independently from each other be hydrogen, a linear or branched alkyl group with 1 to 22 carbon atoms, a linear or branched, simple or polyunsaturated alkenylene group with 2 to 22 carbon atoms, a C6-C22-alkylamidopropyl group, a linear monohydroxyalkyl group with 2 to 10 carbon atoms or a linear or branched dihydroxyalkyl group with 3 to 10 carbon atoms, and wherein at least one of the groups R5, R6 and R7 is not hydrogen.
摘要翻译：描述了包含a）一种或多种式（1）的重复结构单元的聚合物，其中R 1是氢，甲基或乙基，A是C 1 -C 8亚烷基，Q +是H +，NH 4 +，Li +，Na +，K +，½ Ca ++，½Mg ++，½Zn ++或1/3 Al +++，式（1）的结构单元的中和度为50〜100mol％，b）一种或多种式（2）的重复结构单元）其中R 1和A分别是R 1和A，并且X +是[HNR 5 R 6 R 7] +，其中R 5，R 6和R 7可以彼此独立地是氢，具有1至22个碳原子的直链或支链烷基，具有2至22个碳原子的直链或支链，简单或多不饱和亚烯基，C 6 -C 22烷基酰胺基丙基，具有2至10个碳原子的直链单羟基烷基或具有3至10个碳原子的直链或支链二羟烷基，其中基团R5，R6和R7中的至少一个不是氢。

4. 发明申请

US20130313266A1 METHOD TO IMPROVE THE BARRIER PROPERTIES OF COMPOSITE GAS CYLINDERS AND HIGH PRESSURE GAS CYLINDER HAVING ENHANCED BARRIER PROPERTIES 审中-公开
标题翻译：提高复合气瓶缸高阻气体阻尼性能的方法及具有增强阻挡性能的高压气缸
公开(公告)号：US20130313266A1
公开(公告)日：2013-11-28
申请号：US13981951
申请日：2012-01-18
申请人： Roland Andernach , Thomas Lindner
发明人： Roland Andernach , Thomas Lindner
IPC分类号： F17C1/06 , F26B21/10 , B65B53/02
CPC分类号： F17C1/06 , B65B53/02 , F17C1/00 , F17C5/00 , F17C2201/0109 , F17C2201/056 , F17C2201/058 , F17C2203/0604 , F17C2203/0607 , F17C2203/0609 , F17C2203/0673 , F17C2209/2118 , F17C2209/2127 , F17C2209/2154 , F17C2209/22 , F17C2221/033 , F17C2221/035 , F17C2223/0123 , F17C2223/036 , F17C2260/012 , F17C2270/0105 , F17C2270/0168 , F17C2270/02 , F17C2270/0709 , F26B21/10
摘要： Method to improve the barrier properties of composite gas cylinders and high pressure gas cylinder having enhanced barrier properties.The instant invention pertains to a new method for improving the barrier properties of composite gas cylinders for the storage of gas, by wrapping the outer surface of a composite gas cylinder with a plastic film comprising a barrier material in a winding process. The composite gas cylinder comprises an inner liner made of polyolefin and an outer fibre-reinforced, pressure supporting layer. The barrier material may comprise polyamide, polyester, halogen substituted polymer, EVOH or a metallization. The invention pertains also to a high pressure composite gas cylinder having enhanced barrier properties and its use as a fuel tank in gas driven automotive vehicles equipped with a combustion engine.
摘要翻译：提高阻隔性能的复合气瓶和高压气瓶的阻隔性能的方法。本发明涉及一种用于通过在卷绕过程中用包含阻挡材料的塑料膜包裹复合气瓶的外表面来改善用于储存气体的复合气瓶的阻隔性能的新方法。复合气瓶包括由聚烯烃制成的内衬和外纤维增强的压力支撑层。阻挡材料可以包括聚酰胺，聚酯，卤素取代的聚合物，EVOH或金属化。本发明还涉及具有增强的阻隔性能的高压复合气瓶及其在配备内燃机的气体驱动机动车辆中作为燃料箱的用途。

5. 发明申请

US20130250976A1 METHOD FOR THE CLOCK SYNCHRONIZATION OF A PLURALITY OF MODULES 有权
标题翻译：多模态时钟同步的方法
公开(公告)号：US20130250976A1
公开(公告)日：2013-09-26
申请号：US13990919
申请日：2011-01-28
申请人： Thomas Lindner
发明人： Thomas Lindner
IPC分类号： H04J3/06
CPC分类号： H04J3/0644 , H04J3/0602 , H04J3/0638 , H04J3/1688 , H04L7/08
摘要： The invention relates to a method or an arrangement for the clock synchronization of a plurality of distributed modules of an information or communication system, said modules being coupled via a packet-switched network. At least two of said modules are controlled by a local clock generator of the modules using an adjustable frequency, and a clock signal is transmitted via the network in the form of clock signal packets in a synchronous minter with respect to the local clock of the modules. One of said at least two modules takes over the function of a master module, and all remaining said at least two modules, the slave module(s), synchronize the local clock of the modules with the clock of the master module, wherein said slave modules ascertain a measurement for the deviation of the local clock generator of the modules relative to the clock generator of the master module by comparing the clock signal transmitted by the master module with the clock signal of the modules and use said measurement in order to regulate the local clock generator of the modules.
摘要翻译：本发明涉及一种用于信息或通信系统的多个分布式模块的时钟同步的方法或装置，所述模块经由分组交换网络耦合。至少两个所述模块由模块的本地时钟发生器使用可调频率控制，并且时钟信号以时钟信号分组的形式相对于模块的本地时钟以时钟信号分组的形式传输。所述至少两个模块中的一个接管主模块的功能，并且所有剩余的至少两个模块，从模块将模块的本地时钟与主模块的时钟同步，其中所述从站模块通过将主模块发送的时钟信号与模块的时钟信号进行比较，确定模块本地时钟发生器相对于主模块的时钟发生器的偏差的测量，并使用所述测量来调节本地时钟发生器的模块。

6. 发明申请

US20120141714A1 METHOD TO IMPROVE THE BARRIER PROPERTIES OF ETHYLENE POLYMER AGAINST PERMEATION OF HYDROCARBONS AND PLASTIC FUEL TANK HAVING IMPROVED BARRIER PROPERTIES 审中-公开
标题翻译：提高乙烯聚合物阻挡渗透性能的方法及具有改进的阻挡性能的塑料燃料油罐
公开(公告)号：US20120141714A1
公开(公告)日：2012-06-07
申请号：US13376923
申请日：2010-05-29
申请人： Peter Bisson , Bernd Hoecker , Thomas Lindner , Harald Schmitz
发明人： Peter Bisson , Bernd Hoecker , Thomas Lindner , Harald Schmitz
IPC分类号： B32B1/02 , C08K5/3435 , C08K5/3492
CPC分类号： C08F8/22 , C08J7/126 , Y10T428/1397 , C08F10/02
摘要： A method for the improvement of the barrier properties of ethylene homo- or copolymer compositions against permeation of hydrocarbons comprised in liquid fuels or mineral oils is disclosed. The ethylene homo- or copolymer comprises at least one sterically hindered amine compound in an amount of from 100 to 10 000 ppm, calculated on total weight of the polymer. At least one surface of a hollow body made of said ethylene homo- or copolymer is subjected to fluorination.
摘要翻译：公开了一种改进乙烯均聚物或共聚物组合物对液体燃料或矿物油中包含的烃渗透的阻挡性能的方法。乙烯均聚物或共聚物包含至少一种空间位阻胺化合物，其数量为聚合物总重量的100至10000ppm。由所述乙烯均聚物或共聚物制成的中空体的至少一个表面进行氟化。

7. 发明申请

US20110233343A1 Satellite control system 审中-公开
标题翻译：卫星控制系统
公开(公告)号：US20110233343A1
公开(公告)日：2011-09-29
申请号：US12800638
申请日：2010-05-19
申请人： Charles Eric Hunter , Jurgen Klaus Vollrath , John H. Hebrank , Bernard L. Ballou, JR. , Judson Sidney Clements , Thomas Lindner , Ravi Prasad , Phillip E. Russell , Elliot Martin Pines
发明人： Charles Eric Hunter , Jurgen Klaus Vollrath , John H. Hebrank , Bernard L. Ballou, JR. , Judson Sidney Clements , Thomas Lindner , Ravi Prasad , Phillip E. Russell , Elliot Martin Pines
IPC分类号： B64G1/26 , G05D1/00
CPC分类号： B64G1/26
摘要： In a satellite control system, a liquid is ejected by thermal ejection from holes in a substrate structure to create a reactive force on the satellite allowing the position, such as the attitude, of the satellite to be adjusted.
摘要翻译：在卫星控制系统中，通过基板结构中的孔的热喷射来喷射液体，以在卫星上产生反作用力，从而允许调节卫星的位置，例如姿态。

8. 发明申请

US20110160361A1 ETHYLENE POLYMER HAVING IMPROVED RESISTANCE AGAINST THERMOOXIDATIVE DEGRADATION IN THE PRESENCE OF LIQUID FUELS COMPRISING BIODIESEL AND OXYGEN AND PLASTIC FUEL TANK MADE OF IT 有权
标题翻译：乙烯聚合物在包含生物柴油和氧气的液体燃料和塑料燃料油罐的存在下具有改善的抗热性能
公开(公告)号：US20110160361A1
公开(公告)日：2011-06-30
申请号：US12737513
申请日：2009-07-15
申请人： Thomas Lindner , Harald Schmitz
发明人： Thomas Lindner , Harald Schmitz
IPC分类号： C08K5/3435 , C08K5/3492
CPC分类号： C08K5/3435 , C08K5/34926 , C08L23/04
摘要： An ethylene homo- or copolymer composition is stabilized by suitable stabilizers conferring improved resistance against thermo-oxidative degradation, which occurs in the presence of liquid fuels comprising biodiesel, such as vegetable oil esters, in combination with oxygen. The stabilizers comprise a combination of at least two sterically hindered amine compounds or N-hydroxy- or N-oxylderivatives thereof in an amount of from 100 to 10 000 ppm. Such ethylene homo- or copolymer composition is highly suitable for articles of plastic and components for the transport and storage of liquid fuels comprising biodiesel, such as vegetable oil esters, preferably for plastic fuel tanks for automotive vehicles.
摘要翻译：乙烯均聚物或共聚物组合物通过合适的稳定剂稳定，赋予改善的抗热氧化降解的抗性，其在包含生物柴油（例如植物油酯）与氧的组合的液体燃料的存在下发生。稳定剂包含至少两种空间位阻胺化合物或其N-羟基或N-氧代衍生物的组合，其量为100至10000ppm。这种乙烯均聚物或共聚物组合物非常适合用于输送和储存包含生物柴油的液体燃料（例如植物油酯）的塑料制品和组分，优选用于机动车辆的塑料燃料罐。

9. 发明申请

US20100278763A1 Water-Soluble Or Water-Swellable Polymers On The Basis Of Salts Of Acryloyldimethyltaurine Acid Or The Derivatives Thereof, The Production Thereof And The Use Thereof As Thickener, Stabilizer And Consistency Agents 失效
标题翻译：水溶性或水溶性聚合物在丙烯酰基二甲基牛磺酸或其衍生物的基础上，其生产及其用途作为增稠剂，稳定剂和稠度剂
公开(公告)号：US20100278763A1
公开(公告)日：2010-11-04
申请号：US12747727
申请日：2008-12-16
申请人： Matthias Loeffler , Thomas Lindner , Ute Back , Michael Hornung
发明人： Matthias Loeffler , Thomas Lindner , Ute Back , Michael Hornung
IPC分类号： A61K8/81 , C08F228/02 , C08F26/10 , A61K47/32 , A61Q17/04
CPC分类号： A61Q19/08 , A61K8/8158 , A61Q5/006 , A61Q5/06 , A61Q17/04 , A61Q19/007 , A61Q19/02 , A61Q19/10 , C08F220/58 , C08F226/10 , C08F228/02 , C08F2220/585 , C08F2222/1026
摘要： Polymers are described comprising a) one or more of the recurring structural units of the formula (1) where R1 is hydrogen, methyl or ethyl and A is C1-C8 alkylene, and Q+ is H+, NH4+, Li+, Na+, K+, ½Ca++, ½ Mg++, ½ Zn++ or ⅓ Al+++, and the neutralization degree of the structural units of formula (1) is 50 to 100 mol-%, and b) one or more of the recurring structural units of the formula (2) where R1 and A are R1 and A from formula (1) and X+ is [HNR5R6R7]+, where R5, R6 and R7 can independently from each other be hydrogen, a linear or branched alkyl group with 1 to 22 carbon atoms, a linear or branched, simple or polyunsaturated alkenylene group with 2 to 22 carbon atoms, a C6-C22-alkylamidopropyl group, a linear monohydroxyalkyl group with 2 to 10 carbon atoms or a linear or branched dihydroxyalkyl group with 3 to 10 carbon atoms, and wherein at least one of the groups R5, R6 and R7 is not hydrogen, with the proviso that the molar ratio of the structural units of formula (1), where Q+ is NH4+, Li+, Na+, K+, Ca++, Mg++, Zn++ or Al+++, to the structural units of formula (2) is 97:3 to 55:45 and the formation concentration (CMC)
摘要翻译：描述了包含a）一种或多种式（1）的重复结构单元的聚合物，其中R1是氢，甲基或乙基，A是C1-C8亚烷基，Q +是H +，NH4 +，Li +，Na +，K +，½Ca++ ，½Mg ++，½Zn ++或⅓Al+++，式（1）的结构单元的中和度为50至100mol％，和b）一种或多种式（2）的重复结构单元，其中R 1 并且A为式（1）中的R 1和A，X +为[HNR 5 R 6 R 7] +，其中R 5，R 6和R 7可彼此独立地为氢，具有1至22个碳原子的直链或支链烷基，直链或支链具有2至22个碳原子的简单或多不饱和亚烯基，C 6 -C 22烷基酰胺基丙基，具有2至10个碳原子的直链单羟基烷基或具有3至10个碳原子的直链或支链二羟基烷基，并且其中至少一个基团R 5，R 6和R 7不是氢，条件是式（1）的结构单元的摩尔比，对于式（2）的结构单元，Q +为NH 4 +，Li +，Na +，K +，Ca ++，Mg ++，Zn ++或Al +++，为97:3至55:45，形成浓度（CMC）<15g / l和c ）由具有至少两个烯属双键的单体获得的0至8，优选0.01至5重量％的交联结构单元。聚合物例如以化妆品，皮肤病学和药物组合物中的增稠剂的有利方式是合适的。

10. 发明授权

US09834635B2 Polymers based on arcrylic, methacrylic or ethacrylic amidoalkyl sulfonic acid or salts and carboxyalky acrylate, methacrylate or ethacrylate or oligomers of said carboxy compounds 有权
公开(公告)号：US09834635B2
公开(公告)日：2017-12-05
申请号：US13258857
申请日：2010-03-20
申请人： Peter Klug , Dirk Fischer , Thomas Lindner , Matthias Kunze , Wiebke Moeller , Carina Mildner , Sebastiano Lo Vasco
发明人： Peter Klug , Dirk Fischer , Thomas Lindner , Matthias Kunze , Wiebke Moeller , Carina Mildner , Sebastiano Lo Vasco
IPC分类号： A61K31/045 , A61K31/19 , A61K31/192 , A61K31/375 , A61K31/60 , C08F230/02 , A61K8/36 , A61K8/81 , A61Q5/02 , A61Q17/04 , A61Q19/10 , C08F220/26
CPC分类号： C08F230/02 , A61K8/36 , A61K8/8158 , A61Q5/02 , A61Q17/04 , A61Q19/10 , C08F220/26
摘要： Water-soluble or water-swellable polymers are described, containing a) 20.0 to 98.99 mole percent of one or more independently recurring structural units of the formula (1) and b) 1.0 to 79.99 mole percent of one or more independently recurring structural units of the formula (2), and c) 0.01 to 8.0 mole percent of one or more independently recurring cross-linking structural units, which are obtained from one or more monomers having at least two olefinic double bonds. The polymers are suitable, for example, as thickeners or yield point formers, in particular in cosmetic, dermatological or pharmaceutical compositions.

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