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1. 发明申请

WO2010006031A1 GUIDE WIRE LOADING METHOD AND APPARATUS WITH TOWEL ATTACHMENT MECHANISM 审中-公开
标题翻译：指导装载方法和装置与拖车附件机构
公开(公告)号：WO2010006031A1
公开(公告)日：2010-01-14
申请号：PCT/US2009/049912
申请日：2009-07-08
申请人： TEIRSTEIN, Paul, S. , AMINE, Osama , ATKINSON, William , GOULD, William , CHIN, Yem , SCOPTON, Paul , CARMICHAEL, Robert, F., Jr.
发明人： TEIRSTEIN, Paul, S. , AMINE, Osama , ATKINSON, William , GOULD, William , CHIN, Yem , SCOPTON, Paul , CARMICHAEL, Robert, F., Jr.
IPC分类号： A61M25/09
CPC分类号： A61M25/09
摘要： A device for loading a guide wire into the open end of a tubular instrument, such as a catheter. The device can be a block of material having a groove in its surface. The ends of the guide wire and the tubular instrument are placed into the groove and moved toward each other. When the ends meet, the groove guides the guide wire into the open end of the tubular instrument. The groove, or at least a portion of the groove, can have a cross-sectional contour that closely matches the outside radius of the tubular instrument. The groove can have a substantially vertical wall and a substantially non-vertical wall. A variety of attachment mechanisms may be provided for attaching the device to a towel draping a patient.
摘要翻译：用于将导丝装载到管状器械（例如导管）的开口端的装置。该装置可以是在其表面具有凹槽的材料块。引导线和管状器械的端部被放置在槽中并相互移动。当端部相接时，槽将引导线引导到管状器械的开口端。凹槽或凹槽的至少一部分可以具有与管状器械的外半径紧密匹配的横截面轮廓。槽可以具有基本垂直的壁和基本上非垂直的壁。可以提供各种附接机构用于将装置附接到悬垂患者的毛巾。

2. 发明申请

WO1996006654A1 IRRADIATION CATHETER AND METHOD OF USE 审中-公开
标题翻译：辐射导管及其使用方法
公开(公告)号：WO1996006654A1
公开(公告)日：1996-03-07
申请号：PCT/US1995010922
申请日：1995-08-28
申请人： TEIRSTEIN, Paul, S.
IPC分类号： A61M29/00
CPC分类号： A61N5/1002 , A61M25/0023 , A61M25/0029 , A61M25/0032 , A61M25/1002 , A61M2025/0183 , A61M2025/1047 , A61N2005/1003
摘要： This invention is a catheter (10) for use with a radioactive source (16) within the catheter (10) to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood vessel. The catheter (10) has a guidewire channel (18) formed near its distal end to facilitate use of the catheter (10) as a rapid exchange catheter, allowing insertion of the catheter over a guidewire (20) also used in performance of an angioplasty procedure. The catheter (10) can also have a guidewire channel (19) formed near its proximal end to provide O-ring sealing surface and to facilitate free guidewire movement. The catheter (10) also has a closed end (13) to retain the radioactive source (16) within the catheter (10). The catheter (10) can be also be provided with a centering balloon (22) or a set of centering wire loops (50) to center the radioactive source (16) radially within the blood vessel.
摘要翻译：本发明是一种与导管（10）内的放射源（16）一起使用以与血管成形术程序结合照射血管的选定区域以防止血管区域再狭窄的导管（10）。导管（10）具有在其远端附近形成的导丝通道（18），以便于使用导管（10）作为快速交换导管，允许将导管插入也用于执行血管成形术的导丝（20）程序。导管（10）还可以具有在其近端附近形成的导丝通道（19），以提供O形环密封表面并促进自由导丝运动。导管（10）还具有将放射源（16）保持在导管（10）内的封闭端（13）。导管（10）还可以设置有定心球（22）或一组定心线环（50），以使放射源（16）在血管内径向居中。

3. 发明公开

EP2313133A4 GUIDEWIRE AND CATHETER MANAGEMENT DEVICE 审中-公开
标题翻译：用于处理导丝和导管的装置
公开(公告)号：EP2313133A4
公开(公告)日：2011-10-05
申请号：EP09795110
申请日：2009-07-08
申请人： TEIRSTEIN PAUL S
发明人： ATKINSON WILLIAM , GOULD WILLIAM , CHIN YEM , SCOPTON PAUL , CARMICHAEL ROBERT F JR , TEIRSTEIN PAUL S
IPC分类号： A61M5/32
CPC分类号： A61M25/02 , A61M2025/024 , A61M2025/0266 , A61M2025/028

4. 发明公开

EP1083969A4 IRRADIATION CATHETER WITH EXPANDABLE SOURCE 有权
标题翻译：可扩展辐射源导管
公开(公告)号：EP1083969A4
公开(公告)日：2006-11-08
申请号：EP99927159
申请日：1999-06-02
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61M36/04 , A61N5/10 , A61N5/00
CPC分类号： A61N5/1002 , A61N2005/1004
摘要： This patent is a radiation delivery system (10) having an expandable radiation source (14) made of a pliable material. The source body is made of a material such as foam or sponge, or a fibrous material such as soft bristles of a pipe cleaner. The spongy or fibrous material is made radioactive by the implantation of a radioactive isotope. The radioactive isotope can be located throughout the pliable source material (14), or concentrated in a desired region, such as the surface or near-surface region (32). The compressible radioactive source material (14), when constrained by a constraining housing (38) or catheter (38), has a very low profile. When the constraining housing (38) or catheter (38) is withdrawn, the expandable source material (14) expands, and the expandable source material (14) is brought into direct contact with a vessel wall.

5. 发明公开

EP1317945A1 Irradiation catheter 失效
标题翻译：照射导管
公开(公告)号：EP1317945A1
公开(公告)日：2003-06-11
申请号：EP03005672.5
申请日：1995-08-28
申请人： Teirstein, Paul S.
发明人： Teirstein, Paul S.
IPC分类号： A61N5/10 , A61M25/10
CPC分类号： A61N5/1002 , A61M25/0023 , A61M25/0029 , A61M25/0032 , A61M25/1002 , A61M2025/0183 , A61M2025/1047 , A61N2005/1003
摘要： This invention is a catheter (10) for use with a radioactive source (16) within the catheter (10) to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood vessel. The catheter (10) has a guidewire channel (18) formed near its distal end to facilitate use of the catheter (10) as a rapid exchange catheter, allowing insertion of the catheter over a guidewire (20) also used in performance of an angioplasty procedure. The catheter (10) can also have a guidewire channel (19) formed near its proximal end to provide O-ring sealing surface and to facilitate free guidewire movement. The catheter (10) also has a closed end (13) to retain the radioactive source (16) within the catheter (10). The catheter (10) can be also be provided with a centering balloon (22) or a set of centering wire loops (50) to center the radioactive source (16) radially within the blood vessel.
摘要翻译：本发明是一种与导管（10）内的放射源（16）一起使用的导管（10），用于结合血管成形术过程照射血管的选定区域，以防止该血管区域的再狭窄。导管（10）具有形成在其远端附近的导丝通道（18），以便于将导管（10）用作快速交换导管，允许将导管插入也用于实施血管成形术的导丝（20）程序。导管（10）还可以具有在其近端附近形成的导丝通道（19），以提供O形环密封表面并且便于自由导丝移动。导管（10）还具有封闭端（13）以将放射源（16）保持在导管（10）内。导管（10）也可以设置有对中球囊（22）或一组对中线环（50）以使放射源（16）在径向内居中在血管内。

6. 发明公开

EP0788391A4 BODY PASSAGEWAY CLOSURE APPARATUS AND METHOD 失效
标题翻译：方法和装置用于封闭体通道
公开(公告)号：EP0788391A4
公开(公告)日：1999-07-14
申请号：EP95920675
申请日：1995-05-25
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B17/00 , A61B17/12 , A61F2/06 , A61F2/84 , A61M25/00 , A61M29/02 , A61M39/00 , A61M29/00
CPC分类号： A61M29/02 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B2017/00539 , A61B2017/00557 , A61B2017/00575 , A61F2/958 , A61M2025/1052
摘要： A method and apparatus for blocking a body passageway by inserting an expandable frame (40) into the passageway and expanding the frame (40) with an expandable balloon (46) to partially embed the frame (40) in the walls of the passageway. The frame (40) can carry a separate sealing membrane (36), or the balloon (46) can function as the sealing membrane. The sealing membrane (36), the frame (40), or the balloon (46) can also carry a clot promoting substance. The balloon (46) can be removed along with the inflation tube after the expansion procedure, if it is not serving as the sealing membrane (36), or the balloon (46) can be detached from the inflation tube and left in place, either as a sealing membrane or simply to lock the frame in place. The frame can be maintained in its expanded state by being plastically deformed during the expansion step.

7. 发明公开

EP2310078A4 GUIDE WIRE LOADING METHOD AND APPARATUS WITH TOWEL ATTACHMENT MECHANISM 审中-公开
标题翻译：方法和设备，用于加载导丝与TUCHFIXIERMECHANISMUS
公开(公告)号：EP2310078A4
公开(公告)日：2011-10-05
申请号：EP09795106
申请日：2009-07-08
申请人： TEIRSTEIN PAUL S
发明人： AMINE OSAMA , ATKINSON WILLIAM , GOULD WILLIAM , CHIN YEM , SCOPTON PAUL , CARMICHAEL ROBERT F JR , TEIRSTEIN PAUL S
IPC分类号： A61M25/09
CPC分类号： A61M25/09

8. 发明公开

EP2310078A1 GUIDE WIRE LOADING METHOD AND APPARATUS WITH TOWEL ATTACHMENT MECHANISM 审中-公开
标题翻译：具有毛巾附着机构的导丝装载方法和装置
公开(公告)号：EP2310078A1
公开(公告)日：2011-04-20
申请号：EP09795106.5
申请日：2009-07-08
申请人： Teirstein, Paul S.
发明人： AMINE, Osama , ATKINSON, William , GOULD, William , CHIN, Yem , SCOPTON, Paul , CARMICHAEL, Robert, F., Jr. , TEIRSTEIN, Paul, S.
IPC分类号： A61M25/09
CPC分类号： A61M25/09
摘要： A device for loading a guide wire into the open end of a tubular instrument, such as a catheter. The device can be a block of material having a groove in its surface. The ends of the guide wire and the tubular instrument are placed into the groove and moved toward each other. When the ends meet, the groove guides the guide wire into the open end of the tubular instrument. The groove, or at least a portion of the groove, can have a cross-sectional contour that closely matches the outside radius of the tubular instrument. The groove can have a substantially vertical wall and a substantially non-vertical wall. A variety of attachment mechanisms may be provided for attaching the device to a towel draping a patient.
摘要翻译：用于将导丝装入管状器械（如导管）的开口端的装置。该装置可以是在其表面上具有凹槽的材料块。导丝和管状器械的末端放置在凹槽中，并朝向彼此移动。当两端相遇时，凹槽将导丝引导到管状仪器的开口端。凹槽或凹槽的至少一部分可以具有紧密匹配管状器械的外半径的横截面轮廓。凹槽可以具有基本垂直的壁和基本上不垂直的壁。可以提供各种连接机构用于将装置连接到悬挂患者的毛巾上。

9. 发明公开

EP1083969A1 IRRADIATION CATHETER WITH EXPANDABLE SOURCE 有权
标题翻译：可扩展辐射源导管
公开(公告)号：EP1083969A1
公开(公告)日：2001-03-21
申请号：EP99927159.6
申请日：1999-06-02
申请人： Teirstein, Paul S.
发明人： Teirstein, Paul S.
IPC分类号： A61N5/00
CPC分类号： A61N5/1002 , A61N2005/1004
摘要： This patent is a radiation delivery system (10) having an expandable radiation source (14) made of a pliable material. The source body is made of a material such as foam or sponge, or a fibrous material such as soft bristles of a pipe cleaner. The spongy or fibrous material is made radioactive by the implantation of a radioactive isotope. The radioactive isotope can be located throughout the pliable source material (14), or concentrated in a desired region, such as the surface or near-surface region (32). The compressible radioactive source material (14), when constrained by a constraining housing (38) or catheter (38), has a very low profile. When the constraining housing (38) or catheter (38) is withdrawn, the expandable source material (14) expands, and the expandable source material (14) is brought into direct contact with a vessel wall.

10. 发明公开

EP0790842A4 RADIOGRAPHIC DYE DELIVERY APPARATUS AND METHOD 失效
标题翻译：装置和方法在无线电GRAPHIC染料注射
公开(公告)号：EP0790842A4
公开(公告)日：1998-08-12
申请号：EP95939056
申请日：1995-11-07
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B6/00 , A61M5/00 , A61M5/14 , A61M5/36 , A61M5/40 , A61M5/178 , A61M1/00 , A61M1/14 , A61M31/00
CPC分类号： A61M5/007 , A61M5/1412 , A61M5/365 , A61M5/40
摘要： A method and apparatus for injecting radiographic dye during angiography, are provided. A deformable holding chamber (14) is interposed between a contrast dye bottle (12) and a syringe manifold (16). A one-way valve (36) and an integral disconnect/flow stop (28) are connected between the bottle (12) and the holding chamber (14). A vent (54) is provided in the holding chamber (14), with a second one-way valve (58). Squeezing and releasing the deformable chamber (14) fills the chamber (14) from the bottle (12). The holding chamber (14) contains a floating baffle (52) which acts as a shutoff valve by plugging the chamber outlet if the chamber (14) becomes empty. The syringe (50) is used to withdraw dye from the holding chamber (14). If dye remains in the bottle (12) after performance of the procedure, the disconnect/flow stop fitting (28) can be disconnected, and the dye can be saved.

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