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1. 发明专利

BR112022018180A2 OCLUSOR BIODEGRADÁVEL EM FORMA DE PARAQUEDAS 未知
公开(公告)号：BR112022018180A2
公开(公告)日：2022-10-25
申请号：BR112022018180
申请日：2021-03-10
申请人： SHANGHAI SHAPE MEMORY ALLOY CO LTD
发明人： JUAN CHEN , YUNBING WANG , FAN WANG , JINPENG HU , XIANCHUN XU
IPC分类号： A61B17/00 , A61B17/12
摘要： OCLUSOR BIODEGRADÁVEL EM FORMA DE PARAQUEDAS. A presente invenção fornece um oclusor biodegradável em forma de paraquedas, com uma extremidade proximal adjacente a um corpo humano e uma extremidade distal distante do corpo humano. O oclusor biodegradável em forma de paraquedas inclui um stent oclusor dotado internamente de um filme defletor e um anel moldável com estados mutáveis. O stent oclusor, o filme defletor e o anel moldável são feitos, respectivamente, de materiais poliméricos sendo degradáveis em tecidos biológicos. O oclusor é feito de um material polimérico biodegradável, que é degradável ou absorvível pelos tecidos humanos após ser implantado por um período de tempo para fazer um local do defeito composto por tecidos humanos, realizando a oclusão sem matéria estranha. O efeito de oclusão é particularmente significativo para crianças.

2. 发明公开

US20240341956A1 HEART VALVE CLAMP AND MANUFACTURING METHOD THEREFOR 审中-公开
公开(公告)号：US20240341956A1
公开(公告)日：2024-10-17
申请号：US18294502
申请日：2021-08-03
申请人： SHANGHAI SHAPE MEMORY ALLOY CO., LTD.
发明人： Yang Zhao , Xiaojian Liu , Yuxin Zhang
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2220/0008 , A61F2230/0008 , A61F2240/00
摘要： A heart valve clamp includes a fixed arm mechanism and a clamping arm mechanism which includes a clamping arm base, a clamping arm and a first supporting member. The first supporting member is connected to a distal end face of the clamping arm and extends distally in the extending direction of the clamping arm. The width of the first supporting member is greater than the width of the clamping arm. Only the width of an operating part of the clamp is increased, and the overall volume of a conveying system and the clamp are not required to be increased, that is, a clamping area of a valve leaflet is effectively increased, the contact area between the clamp and the valve leaflet after the clamp clamps the valve leaflet is increased, a clamping force of the clamp on the valve leaflet is uniform, the valve leaflet is prevented from being damaged.

3. 发明申请

US20210401454A1 ELECTRODE CATHETER SYSTEM 有权
公开(公告)号：US20210401454A1
公开(公告)日：2021-12-30
申请号：US17056690
申请日：2020-06-29
申请人： Shanghai Shape Memory Alloy Co., Ltd.
发明人： Yishou DING , Xibo ZHANG , Yuxin ZHANG , Jun QIAN , Jing HUANG , Zhongjie PU
IPC分类号： A61B17/32
摘要： The present application provides an electrode catheter system, comprising an interventional catheter for intervening to one side of an artery blood vessel and provided with an electrode element that can release an electrical signal toward an inner wall of a renal artery blood vessel; a pressure sensor for intervening to an artery blood vessel; and a data processing module, connected with the pressure sensor. The electrode element releases an electrical signal toward the inner wall of the renal artery vessel, and then the pressure sensor monitors a blood pressure change in the renal artery vessel at the other side. A data processing module processes the data monitored by the pressure sensor and determines the blood pressure change, and an activity degree of the nerve can be determined by measuring a signal such as the blood pressure of the human body, so as to screen out the patients with an overactive sympathetic nerve, and a surgical effect of a denervation surgery can also be evaluated before or after the surgery, and can be used to determine whether to perform an ultrasonic ablation again.

4. 发明公开

US20240238093A1 RING CONTRACTION APPARATUS FOR MITRAL VALVE ANNULUS 审中-公开
公开(公告)号：US20240238093A1
公开(公告)日：2024-07-18
申请号：US18562655
申请日：2021-05-21
申请人： SHANGHAI SHAPE MEMORY ALLOY CO., LTD.
发明人： Yang ZHAO , Xiaojian LIU , Yuxin ZHANG
IPC分类号： A61F2/24 , A61B17/00 , A61B17/34 , A61M25/00
CPC分类号： A61F2/2466 , A61B17/3478 , A61F2/2454 , A61B2017/00862 , A61F2230/0065 , A61M2025/0095
摘要： A ring contraction apparatus for a mitral valve annulus, comprising at least two fixing mechanisms, a piercing mechanism and a locking mechanism. Each fixing mechanism comprises a fixing knot and a traction wire, the traction wire is mounted on the fixing knot, and two ends of the traction wire are located outside a proximal end of the fixing knot. The piercing mechanism is used for piercing the fixing knots and the traction wires of the fixing mechanisms onto an annulus, so that the fixing knots are located on one side of the annulus and the two ends of the traction wire are located on the other side of the annulus. Traction wires of two adjacent fixing mechanisms are driven by traction forces to approach each other so as to shorten the distance between two adjacent fixing knots.

5. 发明公开

US20240366254A1 PREOPERATIVE DETECTION METHOD AND A POSTOPERATIVE DETECTION METHOD FOR NEUROMAPPING 审中-公开
公开(公告)号：US20240366254A1
公开(公告)日：2024-11-07
申请号：US18778569
申请日：2024-07-19
申请人： SHANGHAI SHAPE MEMORY ALLOY CO., LTD.
发明人： Yishou DING , Xibo ZHANG , Yuxin ZHANG , Jun QIAN , Jing HUANG , Zhongjie PU
IPC分类号： A61B17/32 , A61B5/00 , A61B5/02 , A61B5/0215 , A61B5/022 , A61B5/024 , A61B5/0245 , A61B5/026 , A61B5/027 , A61B5/145 , A61B5/1473 , A61B5/15 , A61B5/24 , A61B5/25 , A61B5/28 , A61B5/283 , A61B5/308 , A61B5/346 , A61B17/00 , A61B17/12 , A61B17/22 , A61B18/00 , A61B18/14 , A61N7/00
CPC分类号： A61B17/320068 , A61B5/0215 , A61B5/0006 , A61B5/0051 , A61B5/0084 , A61B5/02 , A61B5/02233 , A61B5/024 , A61B5/02405 , A61B5/0245 , A61B5/026 , A61B5/027 , A61B5/14503 , A61B5/1473 , A61B5/150847 , A61B5/24 , A61B5/25 , A61B5/28 , A61B5/283 , A61B5/308 , A61B5/346 , A61B5/6853 , A61B2017/00017 , A61B2017/00022 , A61B2017/00044 , A61B2017/00106 , A61B2017/00336 , A61B2017/0034 , A61B2017/00367 , A61B2017/00778 , A61B2017/00862 , A61B17/12022 , A61B2017/12081 , A61B17/12136 , A61B17/1214 , A61B17/2202 , A61B2017/22021 , A61B2017/22051 , A61B2017/22062 , A61B2017/320069 , A61B2017/320072 , A61B2018/00071 , A61B2018/00511 , A61B2018/00577 , A61B2018/00636 , A61B2018/00666 , A61B2018/00702 , A61B2018/00839 , A61B2018/0091 , A61B2018/1405 , A61B2018/1407 , A61B2018/1432 , A61B2018/1435 , A61B2018/144 , A61N2007/003
摘要： The present application provides a preoperative detection method and a postoperative detection method for neuromapping, comprising releasing an electrical signal towards the renal artery blood vessel on one lateral side of the body of the patient by the electrode element; monitoring a heart rate by an electrocardiogram monitoring module, and monitoring a blood pressure change in said another renal artery blood vessel on the other lateral side of the body of the patient by the pressure sensor, and determining a nerve activity degree of the patient by judging whether the heart rate and the blood pressure change reach certain thresholds and making determinations in relation to the nerve activity degree so as to screen out the patients with an overactive sympathetic nerve, and a surgical effect of a denervation surgery can also be evaluated before or after the surgery, and can be used to determine whether to perform an ultrasonic ablation again.

6. 发明公开

US20230277166A1 Parachute-designed biodegradable occluder 审中-公开
公开(公告)号：US20230277166A1
公开(公告)日：2023-09-07
申请号：US18016466
申请日：2021-03-10
申请人： SHANGHAI SHAPE MEMORY ALLOY CO., LTD.
发明人： Juan CHEN , Yunbing WANG , Fan WANG , Jinpeng HU , Xianchun XU
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00606 , A61B2017/00592 , A61B2017/00946 , A61B2017/00871
摘要： A parachute-designed biodegradable occluder is provided. The parachute-designed biodegradable occluder is with a proximal end adjacent to a human body and a distal end far away from the human body. The parachute-designed biodegradable occluder includes an occluder stent internally provided with a baffle film, and a shapeable ring with changeable states. The occluder stent, the baffle film and the shapeable ring are respectively made of polymer materials being degradable in biological tissues. The occluder is made of a biodegradable polymer material, which is degradable or absorbable by human tissues after being implanted for a period of time to make a defect site composed of human tissues, realizing occlusion without foreign matter. The occlusion effect is particularly significant for children.

7. 发明公开

EP4335411A1 RING CONTRACTION APPARATUS FOR MITRAL VALVE ANNULUS 审中-实审
公开(公告)号：EP4335411A1
公开(公告)日：2024-03-13
申请号：EP21940208.8
申请日：2021-05-21
申请人： Shanghai Shape Memory Alloy Co., Ltd.
发明人： ZHAO, Yang , LIU, Xiaojian , ZHANG, Yuxin
IPC分类号： A61F2/24 , A61B17/34
摘要： A ring contraction apparatus for a mitral valve annulus, comprising at least two fixing mechanisms, a piercing mechanism (1) and a locking mechanism (2). Each fixing mechanism comprises a fixing knot (14) and a traction wire (15), the traction wire (15) is mounted on the fixing knot (14), and two ends of the traction wire (15) are located outside a proximal end of the fixing knot (14). The piercing mechanism (1) is used for piercing the fixing knots (14) and the traction wires (15) of the fixing mechanisms onto an annulus, so that the fixing knots (14) are located on one side of the annulus and the two ends of the traction wire (15) are located on the other side of the annulus. Traction wires (15) of two adjacent fixing mechanisms are driven by traction forces to approach each other so as to shorten the distance between two adjacent fixing knots (14), so that an annulus portion between the two adjacent fixing knots (14) is bent or creased, the circumferential length of the annulus is reduced, and the size of an inner hole of the annulus is reduced. Once the distance between the two fixing knots (14) is adjusted in place, the locking mechanism (2) is used to lock end parts of the traction wires (15) in the two adjacent fixing mechanisms to the annulus, so that the annulus is kept in a state in which the inner hole is shrunken, and the annulus is closed more easily, thereby achieving a repair effect.

8. 发明公开

EP4122401A1 BIODEGRADABLE OCCLUDER OF PARACHUTE DESIGN 审中-实审
公开(公告)号：EP4122401A1
公开(公告)日：2023-01-25
申请号：EP21771663.8
申请日：2021-03-10
申请人： Shanghai Shape Memory Alloy Co., Ltd.
发明人： CHEN, Juan , WANG, Yunbing , WANG, Fan , HU, Jinpeng , XU, Xianchun
IPC分类号： A61B17/00 , A61B17/12
摘要： The present invention provides a parachute-shaped biodegradable occluder, with a proximal end adjacent to a human body and a distal end far away from the human body. The parachute-shaped biodegradable occluder includes an occluder stent internally provided with a baffle film, and a shapeable ring with changeable states. The occluder stent, the baffle film and the shapeable ring are respectively made of polymer materials being degradable in biological tissues. The occluder is made of a biodegradable polymer material, which is degradable or absorbable by human tissues after being implanted for a period of time to make a defect site composed of human tissues, realizing occlusion without foreign matter. The occlusion effect is particularly significant for children.

9. 发明公开

EP3960106A1 ELECTRODE CATHETER SYSTEM 有权
公开(公告)号：EP3960106A1
公开(公告)日：2022-03-02
申请号：EP20803731.7
申请日：2020-06-29
申请人： Shanghai Shape Memory Alloy Co., Ltd.
发明人： DING, Yishou , ZHANG, Xibo , ZHANG, Yuxin , QIAN, Jun , HUANG, Jing , PU, Zhongjie
IPC分类号： A61B18/14 , A61N7/02 , A61B5/02 , A61B90/00
摘要： The present application provides an electrode catheter system, comprising an interventional catheter for intervening to one side of an artery blood vessel and provided with an electrode element that can release an electrical signal toward an inner wall of a renal artery blood vessel; a pressure sensor for intervening to an artery blood vessel; and a data processing module, connected with the pressure sensor. The electrode element releases an electrical signal toward the inner wall of the renal artery vessel, and then the pressure sensor monitors a blood pressure change in the renal artery vessel at the other side. A data processing module processes the data monitored by the pressure sensor and determines the blood pressure change, and an activity degree of the nerve can be determined by measuring a signal such as the blood pressure of the human body, so as to screen out the patients with an overactive sympathetic nerve, and a surgical effect of a denervation surgery can also be evaluated before or after the surgery, and can be used to determine whether to perform an ultrasonic ablation again.

10. 发明公开

EP3871626A1 EXPANDING NON-IMPLANTED ATRIAL SHUNT DEVICE 有权
公开(公告)号：EP3871626A1
公开(公告)日：2021-09-01
申请号：EP19928295.5
申请日：2019-12-30
申请人： Shanghai Shape Memory Alloy Co., Ltd.
发明人： HE, Tao , DING, Yishou , ZHANG, Xibo , LI, Xiangyi , CAI, Jie , LIU, Liyun , HE, Ping , CHEN, Hao , ZHANG, Yuxin , PU, Zhongjie
IPC分类号： A61B18/12 , A61B18/14 , A61B18/00
摘要： The application relates to a reaming type non-implanted atrial shunt device comprising a catheter component (2), a radio frequency component (1) disposed on an end of the catheter component (2) extending into a human body, and a radio frequency ablation instrument (4) disposed on the other end of the catheter component (2) and connected with the radio frequency component (1), wherein after the radio frequency component (1) extends into a puncture hole, the radio frequency ablation instrument (4) releases a radio frequency energy, and the radio frequency component (1) ablates a wall of the puncture hole. The radio frequency component (1) is delivered to the position of the puncture hole. When the radio frequency ablation instrument (4) releases energy, the radio frequency component (1) causes the hole wall tissue to generate heat and ablate the atrial septum at a target position to form a hole with fixed size, thereby achieving the purpose of creating a hole. Using radio frequency components (1) to create a hole through radio frequency make the hole not easy to reclose. The hole can effectively drain the left atrium blood into the right atrium, reduce pressure of the left atrium, thereby achieving the purpose of treatment.

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