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1. 发明专利

JP2005255695A Composition useful for production of medicine for treating chronic pain 有权
标题翻译：用于生产用于治疗慢性疼痛的药物的组合物
公开(公告)号：JP2005255695A
公开(公告)日：2005-09-22
申请号：JP2005168442
申请日：2005-06-08
申请人： M Licht Jonathan , Alan Smith Richard , ジョナサン・エム・リッチトJonathan M. Licht , リチャード・アラン・スミスRichard Alan Smith
发明人： RICHARD ALAN SMITH , JONATHAN M LICHT
IPC分类号： A61K31/485 , A61K31/00 , A61K31/138 , A61K31/145 , A61K31/4164 , A61K31/49 , A61P29/00 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To obtain a composition useful for producing a medicine for treating various kinds of obstinate diseases such as chronic pain.
SOLUTION: This composition is a combination of dextromethorphan and a debrisoquin hydroxylase inhibitor. The composition is effective for the treatment of the chronic pain.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：获得用于制备用于治疗各种顽固性疾病如慢性疼痛的药物的组合物。解决方案：该组合物是右美沙芬和片状羟化酶抑制剂的组合。该组合物可有效治疗慢性疼痛。版权所有（C）2005，JPO＆NCIPI

2. 发明专利

JPS5593198A STRING TENSION STABILIZER 失效
公开(公告)号：JPS5593198A
公开(公告)日：1980-07-15
申请号：JP13695879
申请日：1979-10-22
申请人： SMITH RICHARD M
发明人： RICHIYAADO EMU SUMISU
IPC分类号： G10D3/10 , G10C3/00 , G10D3/00

3. 发明专利

JP2005306882A Composition useful for preparation of medicine for treating emotional instability 审中-公开
标题翻译：用于制备治疗情绪不稳定性的药物的组合物
公开(公告)号：JP2005306882A
公开(公告)日：2005-11-04
申请号：JP2005168444
申请日：2005-06-08
申请人： M Licht Jonathan , Alan Smith Richard , ジョナサン・エム・リッチトJonathan M. Licht , リチャード・アラン・スミスRichard Alan Smith
发明人： RICHARD ALAN SMITH , JONATHAN M LICHT
IPC分类号： A61K31/485 , A61K31/135 , A61K31/138 , A61K31/27 , A61K31/4164 , A61K31/4709 , A61P11/14 , A61P15/00 , A61P17/00 , A61P25/04 , A61P25/22 , A61P27/16 , A61P39/06 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To obtain a medical composition for the treatment of a variety of intractable disorders such as emotional instability, especially intractable coughing, dermatitis, chronic pain, tinnitus and sexual dysfunction.
SOLUTION: This invention relates to the composition comprising a combination of dextromethorphan and an inhibitor of debrisoquin hydroxylase selected from quinidine, quinine sulfate, disulfiram, cimetidine, fluoxetine, propanolol, nortriptyline.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：获得用于治疗诸如情绪不稳定性，特别是顽固性咳嗽，皮炎，慢性疼痛，耳鸣和性功能障碍的各种难治性疾病的医疗组合物。解决方案：本发明涉及包含右美沙芬和选自奎尼丁，硫酸奎宁，双硫仑，西咪替丁，氟西汀，丙酰洛伦，去甲替林的失色羟化酶抑制剂的组合物的组合物。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

GB191013362A Improvements in and relating to Vacuum Cleaning Machines. 未知
公开(公告)号：GB191013362A
公开(公告)日：1911-03-09
申请号：GB191013362D
申请日：1910-06-02
申请人： SMITH RICHARD , SMITH RICHARD HALFORD
发明人： SMITH RICHARD , SMITH RICHARD HALFORD
IPC分类号： A47L5/20
摘要： 13,362. Smith, R., and Smith, R. H. June 2. Fixed-abutment type; driving exhausters.- A casing a is provided with an air-tight chamber fitted with a drawer c having a large-surface filter. Below the air-tight chamber is a delivery chamber k divided into compartments in communication with the delivery pipe. Hinged pistons h fitted with packing at the edges, are reciprocated by connecting-rods 2 driven from a crank-shaft u geared by chain or other gear to a motor t. The connecting-rods are fitted with ball bearings of the " Hoffmann type." A staple fixed to the piston h surrounds a disk, through which passes a stud attached to a fork on the connecting-rod.

5. 发明专利

GB191001374A Improvements in and relating to Vacuum Machines for Cleaning Carpets, Billiard Tables and the like. 未知
公开(公告)号：GB191001374A
公开(公告)日：1910-12-31
申请号：GB191001374D
申请日：1910-01-19
申请人： SMITH RICHARD , SMITH RICHARD HALFORD
发明人： SMITH RICHARD , SMITH RICHARD HALFORD
IPC分类号： A47L9/02
摘要： 1374. Smith, R., and Smith, R. H. Jan. 19. [Cognate Application, 13,627/10.] Pivoted handles.-A nozzle a for a vacuum cleaner has one or more suction slots c or the equivalent in its lower face. A swivelling joint e is provided for the connexion of the suctiontube handle d, and wheels h or rollers may be fitted on the screws f which hold the tube d in the cylindrical member e.

6. 发明公开

EP2434990A4 METHODS AND APPARATUS FOR PERFORMING KNEE ARTHROPLASTY 有权
标题翻译：方法和装置用于进行膝关节置换术
公开(公告)号：EP2434990A4
公开(公告)日：2013-02-27
申请号：EP10781303
申请日：2010-05-28
申请人： SMITH & NEPHEW INC , SMITH RICHARD MICHAEL , WILKINSON ZACHARY CHRISTOPHER , LENZ NATHANIEL MILTON , MCKINNON BRIAN W , DRUCKER DAVID A
发明人： SMITH RICHARD MICHAEL , WILKINSON ZACHARY CHRISTOPHER , LENZ NATHANIEL MILTON , MC KINNON BRIAN W , DRUCKER DAVID A
IPC分类号： A61F2/38 , A61B17/15 , A61B17/17 , A61F2/46
CPC分类号： A61B17/155 , A61B17/157 , A61B17/16 , A61B17/1764 , A61F2/3859 , A61F2/389 , A61F2/4684
摘要： Methods and apparatus for performing knee arthroplasty, including, but not limited to, bicruciate retaining knee arthroplasty, are described herein. Methods and apparatus for preparing a distal femur for a femoral implant as well as methods and apparatus for preparing a proximal tibia for a tibial implant are described. These methods and apparatus, in at least some embodiments and uses, facilitate decreasing the complexity of knee arthroplasty procedures such as bicruciate retaining procedures, while maintaining, if not improving on, the safety, accuracy and/or effectiveness of such procedures.

7. 发明公开

EP1334314A1 TILE ROOF RIDGE VENT 审中-公开
标题翻译： FIRST风扇屋顶瓦片
公开(公告)号：EP1334314A1
公开(公告)日：2003-08-13
申请号：EP01964655.3
申请日：2001-08-28
申请人： Smith, Richard D.
发明人： Smith, Richard D.
IPC分类号： F24F7/02
CPC分类号： E04D1/3402 , E04D12/008 , E04D13/174 , F24F7/02
摘要： A tile roof ridge row vent (10) and the method of tis use and consturction are disclosed. The ridge row vent is designed for use with either barrel tile or flat tile. The tile roof ridge row vent includes an elongate member having a vertical section (38) and a side section (40) connected to allow air flow therebetween. The vertical section has a lower sealing skirt that extends under the top row of roof tiles and the side section includes plurality of ventilation openings angled downwardly and outwardly to allow air to exit the vent while preventing rain or other inclement weather from entering the vent. A second embodiment is shown for use with a single sided or mansard type roof. A third embodiment is shown for use in high wind and hurricane prone areas with an angled roof and includes an external baffle added to the ridge row vent. A fourth embodiment utilizing the ridge row vent with the external baffle is shown for use with a mansard type roof.

8. 发明公开

EP1328359A2 METHOD OF ENABLING THE SPACING OF METAL UNITS 审中-公开
标题翻译：嵌套阴极铜
公开(公告)号：EP1328359A2
公开(公告)日：2003-07-23
申请号：EP01953618.4
申请日：2001-07-11
申请人： Smith, Richard
发明人： Smith, Richard
IPC分类号： B21D43/20
CPC分类号： B21D43/20 , Y10T29/49716
摘要： The invention provides means for spacing metal units (512), and means for nesting metal units (532), particularly for stacking, transporting, and industrially altering copper cathodes (512).

9. 发明公开

EP1239860A1 USE OF DEXTROMETHORPHAN AND OXIDASE INHIBITOR FOR WEANING PATIENTS FROM NARCOTICS AND ANTI-DESPRESSANTS 审中-公开
标题翻译：右美沙芬和使用的氧化酶抑制剂麻醉剂和抗抑郁药EINTWOÖHNUNG
公开(公告)号：EP1239860A1
公开(公告)日：2002-09-18
申请号：EP00990294.1
申请日：2000-12-22
申请人： Smith, Richard, Alan
发明人： Smith, Richard, Alan
IPC分类号： A61K31/485 , A61K31/49 , A61P25/36
CPC分类号： A61K31/135 , A61K31/27 , A61K31/44 , A61K31/485 , A61K31/49 , A61K2300/00
摘要： Patients can be helped to break free of addictive or habit-forming narcotics and anti-depressants, by treatment using two drugs. One drug is dextromethorphan (DM), which has been used for decades as an anti-tussive (cough-suppressing) drug in cough syrups. The other drug is an oxidase inhibitor which suppresses activity of a liver enzyme called cytochrome P450-2D6 (also called debrisoquin hydroxylase, sparteine monooxygenase, cytochrome P450-DB, and CYP2D6). In most patients, this oxidase enzyme rapidly degrades DM and converts it into a metabolite called dextrorphan. An oxidase inhibitor (such as quinidine) which suppresses cytochrome P450-2D6 activity increases the half-life and concentration of DM in the circulating blood. When this combined treatment was administered orally to patients who had become dependent on morphine and anti-depressant drugs because of chronic intractable pain, it initially helped the patients reduce their dosages of morphine and other drugs, including anti-depressants. When additional testing was done, the combined treatment allowed patients to entirely terminate all use of morphine and anti-depressants, with minimal withdrawal or other adverse effects. Importantly, these same patients received no substantial benefit from taking dm by itself, without an oxidase inhibitor. Accordingly, the combination of dextromethorphan plus an anti-oxidase drug can allow at least some patients to break entirely free of narcotics and/or anti-depressants, even after years of use for chronic pain and other medical problems, even when they are not substantially helped by dextromethorphan alone.

10. 发明公开

EP1161295A1 MIXING APPARATUS 有权
标题翻译：混合设备
公开(公告)号：EP1161295A1
公开(公告)日：2001-12-12
申请号：EP01942328.4
申请日：2001-01-03
申请人： Rogers, Christopher Roy , Smith, Richard Tipton
发明人： Rogers, Christopher Roy , Smith, Richard Tipton
IPC分类号： B01F11/00 , B01F13/00 , B44D3/12
CPC分类号： B44D3/12 , B01F11/0082 , B01F11/0091 , B01F13/002 , B01F2215/005 , B44D3/08 , Y10S366/605
摘要： A container (1) for liquid and semi-liquid materials such as paint has a bottom wall (2) and a side wall (3). A mixing device (6) is provided in the container, the device having a planar mixing head (7) disposed substantially parallel to the bottom wall (3), and a limb (8) which extends substantially perpendicularly from a peripheral edge region of the mixing head adjacent to the side wall (2) of the container. A coupling (9) is provided in the container for releasable connection with an external handle by which the mixing device is reciprocated vertically to agitate and mix the contents of the container. The handle may have a flattened end for removing a lid (4) from the container.

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