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1. 发明专利

JP2011530677A Air breather valve mechanism 审中-公开
公开(公告)号：JP2011530677A
公开(公告)日：2011-12-22
申请号：JP2011522615
申请日：2008-09-29
申请人：シンハアルンクマルSINHA, Arun, Kumar
发明人：アルンクマルシンハ
IPC分类号： F01M13/00 , F16H57/02
CPC分类号： F16K24/04 , F01M13/0011 , F16K24/06
摘要：本発明は機械的に密封された環境に対して用いられる装置であり、バキュームリリーフバルブ、及び／又は、エアブリーザーバルブと称され、ベントホース仕組及びブリーザーベントを代替するために特別に設計され、これによって機械的に密封された環境における圧力又は吸引量をコントロールし、且つ、動的に制御する構成の装置である。

2. 发明公开

EP2324273A1 AIR BREATHER VALVE ASSEMBLY 审中-公开
标题翻译：呼吸阀安排
公开(公告)号：EP2324273A1
公开(公告)日：2011-05-25
申请号：EP08875990.7
申请日：2008-09-29
申请人： Sinha, Arun Kumar
发明人： Sinha, Arun Kumar
IPC分类号： F16K24/04 , F16K24/06
CPC分类号： F16K24/04 , F01M13/0011 , F16K24/06
摘要： Device for stabilizing air-pressure in a mechanically enclosed environment, namely to a vacuum relief valve and / or air breather valve designed in particular to substitute the vent hose assembly and breather vent and thereby controls and dynamically regulates the pressure or vacuum of the desired area.

3. 发明申请

WO2011058570A1 AIR BREATHER VALVE ASSEMBLY WITH SINGLE VENT AND ONE VALVE DESIGNED TO FLUFF 审中-公开
标题翻译：空气呼吸阀组件与单通风和一个阀设计为FLUFF
公开(公告)号：WO2011058570A1
公开(公告)日：2011-05-19
申请号：PCT/IN2009/000635
申请日：2009-11-12
申请人： SINHA, Arun Kumar
发明人： SINHA, Arun Kumar
IPC分类号： F01M13/00 , F16H3/00 , F16K17/04 , F16K24/00
CPC分类号： F01M13/0011 , F16K24/04
摘要： The present invention relates to an air breather vent assembly with single vent and single valve operable for a mechanically enclosed environment, comprising of a body with a single circular chamber for intake and exhaust; a cap to cover the said body and house the spring, metal tray and valve for intake of fresh air and for exhaust air for oil vapour; wherein the metal tray along with spring assembly is disposed on the top of the metal body which is configured to accommodate the said assembly.
摘要翻译：本发明涉及一种具有可操作于机械封闭环境的单通气孔和单阀的空气通气排气口组件，其包括具有用于进气和排气的单个圆形室的主体; 用于覆盖所述主体并盖住弹簧的盖子，用于吸入新鲜空气的金属托盘和阀门以及用于油蒸气的废气; 其中所述金属托盘与弹簧组件一起设置在所述金属体的顶部上，所述顶部构造成容纳所述组件。

4. 发明申请

WO2010113005A3 ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION 审中-公开
公开(公告)号：WO2010113005A3
公开(公告)日：2010-10-07
申请号：PCT/IB2010/000675
申请日：2010-03-26
申请人： COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH , SHARMA, Abhishek , SINHA, Arun, Kumar , KUMAR, Rakesh , SHARMA, Naina
发明人： SHARMA, Abhishek , SINHA, Arun, Kumar , KUMAR, Rakesh , SHARMA, Naina
IPC分类号： C07C41/30 , C07C43/215 , C07C43/23 , C07C49/84 , C07C51/38 , C07C59/52 , C07C59/68 , C07D317/54 , C07D333/16
摘要： The present invention provides a method for the preparation of some novel multiconj ugated 2- or 4 -hydroxy substituted stilbenes. The method provides one pot multicomponent approach wherein 3-4 step reaction sequences viz. condensation, decarboxylation and Heck coupling occur simultaneously which results in an enhanced yield of desired products and reduced reaction times

5. 发明申请

WO2002079180A1 A METHOD FOR CONVERTING DIHYDROTAGETONE, A BIFUNCTIONAL ACYCLIC MONOTERPENE KETONE INTO 5-ISOBUTYL-3-METHYL-4,5-DIHYDRO-2(3H)-FURANONE AS A ANALOGUE OF NATURAL WHISKY LACTONE AND COCONUT ALDEHYDE 审中-公开
标题翻译：一种将二氢十八烷酮，一种双官能聚环戊二烯酮转化为5-异丁基-3-甲基-4,5-二氢-2（3H） - 呋喃酮的方法，作为天然乳酸和椰子酸的一种模拟物
公开(公告)号：WO2002079180A1
公开(公告)日：2002-10-10
申请号：PCT/IN2001/000057
申请日：2001-03-29
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , SINHA, Arun, Kumar , JOSHI, Bhupendra, Prasad , DOGRA, Ruchi
发明人： SINHA, Arun, Kumar , JOSHI, Bhupendra, Prasad , DOGRA, Ruchi
IPC分类号： C07D307/32
CPC分类号： C07D315/00 , A23L2/56 , A23L27/2052 , A23L27/28 , A24B15/406 , C07C59/185 , C11B9/0076 , C12G3/06
摘要： A natural inexpensive acyclic monoterpene ketone (dihydrotagetone) of formula (4), isolated from the oil of Tagetes sp., was smoothly oxidized with meta-periodate/potassium permanganate into 2,6-dimethyl-4-oxo-heptanoic acid of formula (3), the reduction of 3 with metal hydride such as sodium borohydride or lithium aluminium hydride provided 4-hydroxyacid of formula (2) which on without isolation undergone lactonisation in acidic medium furnished two chiral centered 5-isobutyl-3-methyl-4,5-dihydro-2(3H)-furanone of formula (1) as an analogue of whisky lactone 5-butyl-4-methyl-4,5-dihydro-2(3H)-furanone of formula (1a) responsible for high quality of alcoholic beverage (whisky, wine, brandy and scotch), in addition, coconut flavoured 5-butyl-4-methyl-4,5-dihydro-2(3H)-furanone of formula (1) is also as an analogue of coconut aldehyde (g-nonalactone, F.E.M.A. No. 2751) of formula (1b) which is responsible for flavouring a wide range of food stuffs including baked goods and confectionery.
摘要翻译：从Tagetes sp。油中分离得到的式（4）的天然廉价的无环单萜酮（二氢t酮）用高碘酸钾/高锰酸钾被平滑地氧化成式（4）的2,6-二甲基-4-氧代 - 庚酸， 3）中，用金属氢化物如硼氢化钠或氢化铝锂还原3，得到式（2）的4-羟基酸，其在酸性介质中经过内酯化而没有分离，提供了两个手性中心的5-异丁基-3-甲基-4- （1）的5-二氢-2（3H） - 呋喃酮作为负责高品质的式（1a）的威士忌内酯5-丁基-4-甲基-4,5-二氢-2（3H） - 呋喃酮的类似物的酒精饮料（威士忌，葡萄酒，白兰地和苏格兰威士忌），此外，式（1）的椰子风味的5-丁基-4-甲基-4,5-二氢-2（3H） - 呋喃酮也是椰子的类似物式（1b）的醛（g-非内酯，FEMA No.2751），其负责调味各种食品，包括焙烤食品和糖果。

6. 发明申请

WO2011058571A1 AIR BREATHER ASSEMBLY WITH SINGLE VENT AND WITH SINGLE / TWIN BALL VALVES 审中-公开
标题翻译：具有单通风和单/双球阀的空气呼吸器总成
公开(公告)号：WO2011058571A1
公开(公告)日：2011-05-19
申请号：PCT/IN2009/000636
申请日：2009-11-12
申请人： SINHA, Arun Kumar
发明人： SINHA, Arun Kumar
IPC分类号： F01M13/00 , F16H57/02
CPC分类号： F01M13/0011 , F16H57/027
摘要： The present invention relates to an air breather vent assembly operable for a mechanically enclosed environment, comprising of a body with a circular centrally oriented exhaust and intake chamber; plurality of ball valves, plurality of diamond polish seats, spacers, spring, a cap to cover the said body; an air and oil filter housed in the side chamber of the body for intake of fresh air and oil filter for exhaust air impregnated with oil vapour disposed over the said chamber.
摘要翻译：本发明涉及一种可操作用于机械封闭环境的通气孔通气组件，其包括具有圆形中心定向排气和进气室的主体; 多个球阀，多个金刚石抛光座，间隔件，弹簧，盖子覆盖所述主体; 容纳在主体的侧室中的空气和油过滤器，用于吸入新鲜空气和油过滤器，用于浸渍设置在所述室上的油蒸汽的废气。

7. 发明申请

WO2010097811A1 MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES 审中-公开
标题翻译：微波诱导的单步绿色合成一些新型二芳基醛及其类似物
公开(公告)号：WO2010097811A1
公开(公告)日：2010-09-02
申请号：PCT/IN2010/000110
申请日：2010-02-25
申请人： COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH , SINHA, Arun, Kumar , SHARMA, Abhishek , KUMAR, Rakesh , SHARMA, Naina
发明人： SINHA, Arun, Kumar , SHARMA, Abhishek , KUMAR, Rakesh , SHARMA, Naina
IPC分类号： C07C45/30 , C07C311/49 , C07D317/54 , C07C47/228 , C07C47/23 , C07C47/24 , C07C47/277
CPC分类号： C07C45/28 , C07C45/30 , C07C249/16 , C07C311/49 , C07D317/54 , C07C47/228 , C07C47/24 , C07C47/23 , C07C47/277
摘要： The present invention provides a process for the preparation of some novel 2-aryl and 2,2-diaryl aldehydes and analogues which are privileged intermediates for commercially important nonsteroidal anti-inflammatory drugs including naproxen, flurbiprofen and potent anticancer drug candidates, including phenstatin through a unique single step synthetic methodology utilizing easily available substrates in the form of aryl alkenes as well as environmentally benign aqueous reaction conditions in the form of solvents such as mixtures of water and DMSO or Dioxane and reagents N-bromosuccinimide, N- iodosuccinimide, N-cholorosuccinimide and phase transfer catalyst such as cetyltrimethyl ammonium bromide, N-hexyl ammonium chloride for a reaction time varying from 1min- 30min, depending upon microwave or conventional heating, without using expensive transition metal catalysts or lewis acids/bases with yield varying from 35-55 %, depending upon the solvent and substrate used. The developed method provides a clean and convenient alternative to access a diverse range of medicinally important 2-aryl and 2,2- diaryl aldehyde based scaffolds in lieu of the conventional multistep protocols employing expensive and hazardous transition metal catalysts and lewis acids/bases.
摘要翻译：本发明提供了制备一些新的2-芳基和2,2-二芳基醛和类似物的方法，它们是商业上重要的非甾体抗炎药物的特权中间体，包括萘普生，氟比洛芬和有效的抗癌药物候选物，包括通过利用芳基烯烃形式的容易获得的底物以及以水和DMSO或二恶烷的混合物和二恶烷的溶剂形式的环境友好的水性反应条件的独特的单步合成方法和试剂N-溴代琥珀酰亚胺，N-碘代琥珀酰亚胺，N-氯代琥珀酰亚胺和相转移催化剂如十六烷基三甲基溴化铵，N-己基氯化铵，反应时间根据微波或常规加热反应时间为1min-30min，而不使用昂贵的过渡金属催化剂或路易斯酸/碱，产率从35-55 取决于所用的溶剂和底物。开发的方法提供了一种干净和方便的替代方案，用于获得各种各样的药物重要的2-芳基和2,2-二芳基醛基支架，代替采用昂贵且危险的过渡金属催化剂和路易斯酸/碱的常规多步骤方案。

8. 发明申请

WO2003082786A1 A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ALPHA-ASARONE FROM TOXIC BETA-ASARONE RICH ACORUS CALAMUS OIL 审中-公开
标题翻译：一种制备药物活性阿尔法 - 阿斯巴龙的毒素阿托品的研究方法
公开(公告)号：WO2003082786A1
公开(公告)日：2003-10-09
申请号：PCT/IN2002/000094
申请日：2002-03-28
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , SINHA, Arun, Kumar , ACHARYA, Ruchi , JOSHI, Bhupendra, Prasad
发明人： SINHA, Arun, Kumar , ACHARYA, Ruchi , JOSHI, Bhupendra, Prasad
IPC分类号： C07C41/18
CPC分类号： C07C41/18 , C07C43/215 , C07C45/28 , C07C45/30 , C07C47/277 , C07C49/255
摘要： The present invention relates to a process for the preparation of high purity and yield α-asarone, trans 2,4,5-trimethoxy cinnamaldehyde, 2,4,5-trimethoxy-phenyl propionone, from β-asarone or β-asarone rich Acorus calamus oil containing α and γ-asarone by hydrogenating, followed by treatment with DDQ with or without solid support of silica gel or alumina in dry organic solvent and α-asarone can also be obtained by treating the hydrogenated product of β-asarone or β-asarone rich Acorus calamus with DDQ in an aqueous organic solvent to obtain an intermediate 2,4,5-trimethoxy phenyl propionone, which in turn is reduced with sodiumborohydride to obtain the corresponding 2,4,5-trimethoxy-phenyl propanol and followed by final treatment with a dehydrating agent.
摘要翻译：本发明涉及一种制备高纯度和产率的α-阿萨罗酮，反式2,4,5-三甲氧基肉桂醛，2,4,5-三甲氧基苯丙酮，由β-佐酮或富含β-甲砜的Acorus 通过氢化含有α和γ-阿萨罗酮的菖蒲油，然后通过用干燥有机溶剂和α-阿萨罗酮处理含有或不含硅胶或氧化铝的固体支持物的DDQ，也可以通过将β-阿扎酮或β- 在含水有机溶剂中含有DDQ的asarone丰富的Acorus calamus，得到中间体2,4,5-三甲氧基苯丙酮，然后用硼氢化钠还原，得到相应的2,4,5-三甲氧基 - 苯基丙醇，用脱水剂处理。

9. 发明申请

WO2002079132A1 MICROWAVE ASSISTED PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLALDEHYDES FROM TRANS AND CIS-PHENYLPROPENES 审中-公开
标题翻译：用于从转移和联苯基丙烯酸制备取代的苯甲醛的微波辅助方法
公开(公告)号：WO2002079132A1
公开(公告)日：2002-10-10
申请号：PCT/IN2001/000060
申请日：2001-03-29
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , SINHA, Arun, Kumar , JOSHI, Bhupendra, Prasad , DOGRA, Ruchi
发明人： SINHA, Arun, Kumar , JOSHI, Bhupendra, Prasad , DOGRA, Ruchi
IPC分类号： C07C45/30
CPC分类号： C07C45/30 , C07C45/28 , C07C45/78 , C07C47/575
摘要： The present invention provides microwave assisted rapid and economical process for the preparation of substituted phenylaldehydes from trans and cis-phenylpropene, a commercial utilization of toxic cis-isomer of the general formula (I) as shown in figure 4 of the accompanying drawings, using meta-periodate and osmium tetraoxide (catalytic amount) as an efficient oxidizing agent in the presence of co-catalyst namely amberlite IRA-410 and quaternary ammonium salt.
摘要翻译：本发明提供微波辅助的快速和经济的方法，用于从反式和顺式 - 苯基丙烯制备取代的苯基醛，商业上利用如附图4所示的通式（I）的有毒顺式异构体，使用元（催化量）作为有效氧化剂，在助催化剂即琥珀酸IRA-410和季铵盐存在下进行。

10. 发明申请

WO2004056733A1 A MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED 4-VINYLPHENOLS 审中-公开
标题翻译：用于制备取代的4-乙烯基苯酚的微波诱导方法
公开(公告)号：WO2004056733A1
公开(公告)日：2004-07-08
申请号：PCT/IB2002/005513
申请日：2002-12-19
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , SINHA, Arun, Kumar , JOSHI, Bhupendra, Prasad , SHARMA, Anuj
发明人： SINHA, Arun, Kumar , JOSHI, Bhupendra, Prasad , SHARMA, Anuj
IPC分类号： C07C37/20
CPC分类号： C07C43/23 , C07C37/20 , C07C41/30 , C07C51/353 , C07C51/38 , C07C59/52 , C07C59/64 , C07C39/20
摘要： The present invention relates to "A microwave induced process for the preparation of substituted 4-vinylphenols" in which commercially important FEMA GRAS approved perfumery and flavouring vinylphenols (i.e. hydroxystyrenes) namely 4-vinylguaiacol (FEMA GRAS No. 2675) and 4-vinylphenol (FEMA GRAS No. 3739) as well as other useful vinylphenols such as 2,6-dimethoxy-4-vinylphenol, 2-hydroxy-4-vinylphenol, 3-hydroxy-4-vinylphenol etc. are obtained in a one pot during condensation of malonic acid and corresponding substituted 4-hydroxyphenylaldehydes (4-hydroxy benzaldehydes) under microwave irradiation.
摘要翻译：本发明涉及“用于制备取代的4-乙烯基苯酚的微波诱导方法”，其中商业上重要的FEMA GRAS批准了香料和调味乙烯基苯酚（即羟基苯乙烯），即4-乙烯基愈创木酚（FEMA GRAS No.2675）和4-乙烯基苯酚 FEMA GRAS No.3739）以及其它有用的乙烯基苯酚如2,6-二甲氧基-4-乙烯基苯酚，2-羟基-4-乙烯基苯酚，3-羟基-4-乙烯基苯酚等在一锅中在丙二酸和相应的取代的4-羟基苯基醛（4-羟基苯甲醛）。

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