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1. 发明申请

WO2010092597A2 LIPOSOMAL CITICOLINE INJECTION 审中-公开
标题翻译：脂质中性粒细胞注射
公开(公告)号：WO2010092597A2
公开(公告)日：2010-08-19
申请号：PCT/IN2010/000074
申请日：2010-02-10
申请人： LYKA LABS LIMITED , MISRA, Ambikanandan, Rajnarayan , GANDHI, Narendra, Ishwarlal , BAJAJ, Mannalal, Ramgopal , SHAH, Bharat, Babulal , SAMANT, Rajan, Shantaram , JAMIL, Ahmad, Sattar, Pinjari
发明人： MISRA, Ambikanandan, Rajnarayan , GANDHI, Narendra, Ishwarlal , BAJAJ, Mannalal, Ramgopal , SHAH, Bharat, Babulal , SAMANT, Rajan, Shantaram , JAMIL, Ahmad, Sattar, Pinjari
IPC分类号： A61K9/127
CPC分类号： A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/1278 , A61K31/7068
摘要： Disclosed herein is a stable sustained release liposomal injection comprising Citicoline entrapped in the ammonium sulfate liposomes, useful to enhance brain uptake efficiency.
摘要翻译：本文公开了稳定的持续释放脂质体注射液，其包含截留在硫酸铵脂质体中的胞质碱，其可用于增强大脑摄取效率。

2. 发明申请

WO2005065682A2 A NOVEL DRUG DELIVERY SYSTEM FOR PROTON PUMP INHIBITORS AND PROCESS THEREOF 审中-公开
标题翻译：含有吡喹酮的制剂
公开(公告)号：WO2005065682A2
公开(公告)日：2005-07-21
申请号：PCT/IN2004/000342
申请日：2004-11-03
申请人： LYKA LABS LIMITED , BAJAJ, Mannalal, Ramgopal , SAMANT, Rajan, Shantaram , SHAH, Bharat, Babulal
发明人： BAJAJ, Mannalal, Ramgopal , SAMANT, Rajan, Shantaram , SHAH, Bharat, Babulal
IPC分类号： A61K31/4184
CPC分类号： A61K31/4184 , A61K9/0019 , A61K47/26
摘要： The present invention discloses a novel drug delivery system for proton pump inhibitors comprising benzimidazole compounds or their salts, preferably Rabeprazole or its salts and pharmaceutically acceptable excipients in powder form which is reconstitutable in a parenterally acceptable solvent to form an injectable solution.
摘要翻译：本发明公开了一种用于质子泵抑制剂的药物递送系统，其包括苯并咪唑化合物或其盐，优选雷贝拉唑或其盐和药学上可接受的粉末形式的赋形剂，其可在胃肠外可接受的溶剂中重构以形成可注射溶液。

3. 发明申请

WO0130759A3 SODIUM-HYDROGEN EXCHANGER TYPE 1 INHIBITOR CRYSTALS 审中-公开
标题翻译：钠氢交换器1型抑制剂水晶
公开(公告)号：WO0130759A3
公开(公告)日：2001-09-13
申请号：PCT/IB0001460
申请日：2000-10-09
申请人： PFIZER PROD INC , BROSTROM LYLE ROBINSON , CONNOLLY TERRENCE JOSEPH , LI ZHENG JANE , ORRILL SUSAN LEE , SHAH BHARAT KIRITKUMAR
发明人： BROSTROM LYLE ROBINSON , CONNOLLY TERRENCE JOSEPH , LI ZHENG JANE , ORRILL SUSAN LEE , SHAH BHARAT KIRITKUMAR
IPC分类号： A61K20060101 , A61K31/352 , A61K31/4155 , A61K31/4709 , A61P20060101 , A61P3/10 , A61P9/10 , A61P11/00 , A61P13/08 , A61P21/00 , A61P35/00 , A61P39/00 , A61P41/00 , A61P43/00 , B01D9/02 , C07D20060101 , C07D231/00 , C07D401/04 , C07D401/10
CPC分类号： C07D401/04
摘要： NHE-1 inhibitor crystal of Formula (I), methods of using such NHE-1 inhibitor crystal and pharmaceutical compositions containing such NHE-1 inhibitor crystal. The NHE-1 inhibitor crystal is useful for the reduction of tissue damage resulting from tissue ischemia.
摘要翻译：式（I）的NHE-1抑制剂晶体，使用这种NHE-1抑制剂晶体的方法和含有这种NHE-1抑制剂晶体的药物组合物。 NHE-1抑制剂晶体可用于减少由组织缺血引起的组织损伤。

4. 发明申请

WO2011048613A3 EMERGENCY CONTRACEPTIVE 审中-公开
标题翻译：紧急合同
公开(公告)号：WO2011048613A3
公开(公告)日：2012-01-12
申请号：PCT/IN2010000676
申请日：2010-10-12
申请人： LYKA LABS LTD , MISRA AMBIKANANDAN RAJNARAYAN , GANDHI NARENDRA ISHWARLAL , BAJAJ MANNALAL RAMGOPAL , SHAH BHARAT BABULAL , SAMANT RAJAN SHANTARAM
发明人： MISRA AMBIKANANDAN RAJNARAYAN , GANDHI NARENDRA ISHWARLAL , BAJAJ MANNALAL RAMGOPAL , SHAH BHARAT BABULAL , SAMANT RAJAN SHANTARAM
IPC分类号： A61K9/107 , A61K9/127 , A61K9/14 , A61K9/19 , A61K31/565
CPC分类号： A61K9/0043 , A61K9/0073 , A61K9/0075 , A61K9/1075 , A61K9/127 , A61K9/146 , A61K9/19 , A61K31/565 , A61K47/32 , A61K47/36
摘要： The present invention discloses an emergency contraceptive formulation for nasal and/or pulmonary administration comprising of levonorgestrel optionally in combination with ethylestradiol. The said formulation can be in form of solution, suspension or carrier based systems selected from microemulsion and liposomes.
摘要翻译：本发明公开了一种用于鼻和/或肺部给药的紧急避孕制剂，其包含任选与乙雌二醇组合的左炔诺孕酮。所述制剂可以是选自微乳液和脂质体的溶液，悬浮液或载体系统的形式。

5. 发明申请

WO2011055383A3 INTRANASAL DELIVERY TO IMPROVE THE PERFORMANCE OF CHILDREN SUFFERING FROM DYSLEXIA 审中-公开
标题翻译：通过内源性递送改善儿童摆脱心理症状的表现
公开(公告)号：WO2011055383A3
公开(公告)日：2011-06-30
申请号：PCT/IN2010000719
申请日：2010-11-01
申请人： LYKA LABS LTD , MISRA AMBIKANANDAN RAJNARAYAN , GANDHI NARENDRA ISHWARLAL , BAJAJ MANNALAL RAMGOPAL , SHAH BHARAT BABULAL , SAMANT RAJAN SHANTARAM , RANA HEMAL
发明人： MISRA AMBIKANANDAN RAJNARAYAN , GANDHI NARENDRA ISHWARLAL , BAJAJ MANNALAL RAMGOPAL , SHAH BHARAT BABULAL , SAMANT RAJAN SHANTARAM , RANA HEMAL
IPC分类号： A61K31/137
CPC分类号： A61K31/137 , A61K9/0043 , A61K9/0075 , A61K9/107 , A61K9/127 , A61K9/146 , A61K9/1647 , A61K9/2054 , A61K9/5031 , A61K45/06 , A61K2300/00
摘要： The invention discloses a pharmaceutical composition comprising therapeutically effective amount of stimulants, anti-motion drugs and nootropics, either alone or in combination, administered through, oral, intranasal or intravenous, for the treatment and/or management of dyslexia.
摘要翻译：本发明公开了一种药物组合物，其包含治疗有效量的兴奋剂，抗运动药和促智药，单独或联合给药，通过口服，鼻内或静脉内给药，用于治疗和/或处理诵读困难。

6. 发明申请

WO2011055383A2 INTRANASAL DELIVERY TO IMPROVE THE PERFORMANCE OF CHILDREN SUFFERING FROM DYSLEXIA 审中-公开
标题翻译：进一步提高儿童从DYSLEXIA发展的成绩
公开(公告)号：WO2011055383A2
公开(公告)日：2011-05-12
申请号：PCT/IN2010/000719
申请日：2010-11-01
申请人： LYKA LABS LIMITED , MISRA, Ambikanandan, Rajnarayan , GANDHI, Narendra, Ishwarlal , BAJAJ, Mannalal, Ramgopal , SHAH, Bharat, Babulal , SAMANT, Rajan, Shantaram , RANA, Hemal
发明人： MISRA, Ambikanandan, Rajnarayan , GANDHI, Narendra, Ishwarlal , BAJAJ, Mannalal, Ramgopal , SHAH, Bharat, Babulal , SAMANT, Rajan, Shantaram , RANA, Hemal
IPC分类号： A61K31/137
CPC分类号： A61K31/137 , A61K9/0043 , A61K9/0075 , A61K9/107 , A61K9/127 , A61K9/146 , A61K9/1647 , A61K9/2054 , A61K9/5031 , A61K45/06 , A61K2300/00
摘要： The invention discloses a pharmaceutical composition comprising therapeutically effective amount of stimulants, anti-motion drugs and nootropics, either alone or in combination, administered through, oral, intranasal or intravenous, for the treatment and/or management of dyslexia.
摘要翻译：本发明公开了一种药物组合物，其包含治疗和/或管理阅读障碍的治疗有效量的单独或组合的刺激剂，抗运动药物和益智药，通过，口服，鼻内或静脉内施用。

7. 发明申请

WO2010023674A1 PROCESS FOR PRODUCTION OF TRI CHOLINE CITRATE AND COMPOSITION THEREOF 审中-公开
标题翻译：柠檬酸三辛酯的生产方法及其组合物
公开(公告)号：WO2010023674A1
公开(公告)日：2010-03-04
申请号：PCT/IN2008/000542
申请日：2008-08-27
申请人： SHAH, Bharat, Shantilal
发明人： SHAH, Bharat, Shantilal
IPC分类号： C07D475/00 , C07D475/04
CPC分类号： C07C215/40 , C07C51/412 , C07C51/47 , Y02P20/582 , C07C59/265
摘要： The present invention is related to novel process for production of Tricholine Citrate by reacting citric acid with choline base at high temperature to obtained more than 65 percent pure of Tricholine Citrate. Such a obtained Tricholine Citrate is used in various composition for used as an effective iron chelator and used to stabilize animal growth hormone preparations also The invention provides a novel process for of production of Tricholine Citrate by reacting Citric acid with choline base solution at high temperature and distillation of Trichoiine Citrate at the same time in single step. In the process, citric acid is reacted with choline base solution at above 50 degree Celsius by adjusting pH of solution above 8.5 de-colorizing the solution obtained by de colorizing agent. The obtained product is filtered at temperature below the 40 degree Celsius in filtration unit and then distilled in Distillation Column to obtained high purity of Tricholine Citrate.
摘要翻译：本发明涉及柠檬酸柠檬酸与胆碱碱在高温下反应生产柠檬酸三钙的新方法，以获得超过65％的柠檬酸三钙。所得到的柠檬酸三氯化铁用于各种组合物中，用作有效的铁螯合剂，并用于稳定动物生长激素制剂本发明提供了一种通过柠檬酸与胆碱碱溶液在高温下反应生产柠檬酸三钙的新方法，同时在一步中蒸馏柠檬酸铁屑。在此过程中，柠檬酸与摄氏50度以上的胆碱碱溶液相比，通过调节8.5以上溶液的pH使脱色剂得到的溶液脱色。将获得的产物在过滤单元中在低于40摄氏度的温度下过滤，然后在蒸馏塔中蒸馏以获得高纯度的柠檬酸三里皮。

8. 发明申请

WO2005065682A3 RABEPRAZOLE CONTAINING FORMULATION 审中-公开
标题翻译：含有雷贝拉唑的制剂
公开(公告)号：WO2005065682A3
公开(公告)日：2005-09-01
申请号：PCT/IN2004000342
申请日：2004-11-03
申请人： LYKA LABS LTD , BAJAJ MANNALAL RAMGOPAL , SAMANT RAJAN SHANTARAM , SHAH BHARAT BABULAL
发明人： BAJAJ MANNALAL RAMGOPAL , SAMANT RAJAN SHANTARAM , SHAH BHARAT BABULAL
IPC分类号： A61K9/00 , A61K31/4184 , A61K47/26
CPC分类号： A61K31/4184 , A61K9/0019 , A61K47/26
摘要： The present invention discloses a novel drug delivery system for proton pump inhibitors comprising benzimidazole compounds or their salts, preferably Rabeprazole or its salts and pharmaceutically acceptable excipients in powder form which is reconstitutable in a parenterally acceptable solvent to form an injectable solution.
摘要翻译：本发明公开了质子泵抑制剂的新型药物递送系统，其包含苯并咪唑化合物或其盐，优选雷贝拉唑或其盐以及粉末形式的药学上可接受的赋形剂，其可在胃肠外可接受的溶剂中重构以形成可注射溶液。

9. 发明申请

WO2011048613A2 EMERGENCY CONTRACEPTIVE 审中-公开
标题翻译：紧急合同
公开(公告)号：WO2011048613A2
公开(公告)日：2011-04-28
申请号：PCT/IN2010/000676
申请日：2010-10-12
申请人： LYKA LABS LIMITED , MISRA, Ambikanandan Rajnarayan , GANDHI, Narendra Ishwarlal , BAJAJ, Mannalal Ramgopal , SHAH, Bharat Babulal , SAMANT, Rajan Shantaram
发明人： MISRA, Ambikanandan Rajnarayan , GANDHI, Narendra Ishwarlal , BAJAJ, Mannalal Ramgopal , SHAH, Bharat Babulal , SAMANT, Rajan Shantaram
IPC分类号： A61K9/107
CPC分类号： A61K9/0043 , A61K9/0073 , A61K9/0075 , A61K9/1075 , A61K9/127 , A61K9/146 , A61K9/19 , A61K31/565 , A61K47/32 , A61K47/36
摘要： The present invention discloses an emergency contraceptive formulation for nasal and/or pulmonary administration comprising of levonorgestrel optionally in combination with ethylestradiol. The said formulation can be in form of solution, suspension or carrier based systems selected from microemulsion and liposomes.
摘要翻译：本发明公开了一种用于鼻和/或肺部给药的紧急避孕制剂，其包含任选与乙雌二醇组合的左炔诺孕酮。所述制剂可以是选自微乳液和脂质体的溶液，悬浮液或载体系统的形式。

10. 发明申请

WO2010092597A3 LIPOSOMAL CITICOLINE INJECTION 审中-公开
标题翻译：脂质中性粒细胞注射
公开(公告)号：WO2010092597A3
公开(公告)日：2011-03-24
申请号：PCT/IN2010000074
申请日：2010-02-10
申请人： LYKA LABS LTD , MISRA AMBIKANANDAN RAJNARAYAN , GANDHI NARENDRA ISHWARLAL , BAJAJ MANNALAL RAMGOPAL , SHAH BHARAT BABULAL , SAMANT RAJAN SHANTARAM , JAMIL AHMAD SATTAR PINJARI
发明人： MISRA AMBIKANANDAN RAJNARAYAN , GANDHI NARENDRA ISHWARLAL , BAJAJ MANNALAL RAMGOPAL , SHAH BHARAT BABULAL , SAMANT RAJAN SHANTARAM , JAMIL AHMAD SATTAR PINJARI
IPC分类号： A61K9/127 , A61K31/7068
CPC分类号： A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/1278 , A61K31/7068
摘要： Disclosed herein is a stable sustained release liposomal injection comprising Citicoline entrapped in the ammonium sulfate liposomes, useful to enhance brain uptake efficiency.
摘要翻译：本文公开了稳定的持续释放脂质体注射液，其包含截留在硫酸铵脂质体中的胞质碱，其用于增强大脑摄取效率。

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