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1. 发明申请

US20130205981A1 Vehicle Floor Pan Comprising Auxiliary Armoring 有权
标题翻译：车底盘包括辅助装甲
公开(公告)号：US20130205981A1
公开(公告)日：2013-08-15
申请号：US13643075
申请日：2011-04-15
申请人： Robert Bayer , Christian Schwippi
发明人： Robert Bayer , Christian Schwippi
IPC分类号： F41H7/04 , F41H5/013 , F41H5/04
CPC分类号： F41H7/042 , F41H5/013 , F41H5/04
摘要： A floor pan of a vehicle, in particular an armored military vehicle, includes a first, lateral floor wall (1); a second, floor wall which is connected via connecting point (9) with the first, lateral wall (1); and an auxiliary armoring (4) releasably attached to the lateral floor wall (1) for mine protection. The auxiliary armoring is an armored plate that at least partially covers the second, floor wall (5) adjacent the lateral floor wall (1) and the connecting point (9) lying therebetween.
摘要翻译：车辆的平底锅，特别是装甲军车，包括第一侧面地板壁（1）; 通过连接点（9）与第一侧壁（1）连接的第二底壁; 以及可释放地附接到侧壁（1）的用于防雷的辅助铠装（4）。辅助铠装是铠装板，其至少部分地覆盖邻近侧壁（1）和位于其间的连接点（9）的第二底壁（5）。

2. 发明授权

US08008252B2 Factor VII: remodeling and glycoconjugation of Factor VII 失效
标题翻译：因子VII：因子VII的重塑和糖结合
公开(公告)号：US08008252B2
公开(公告)日：2011-08-30
申请号：US10411044
申请日：2003-04-09
申请人： Shawn DeFrees , David Zopf , Robert Bayer , Caryn Bowe , David Hakes , Xi Chen
发明人： Shawn DeFrees , David Zopf , Robert Bayer , Caryn Bowe , David Hakes , Xi Chen
IPC分类号： A61K38/16
CPC分类号： C12N9/647 , C12N9/6437 , C12P21/005 , C12Y304/21021
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
摘要翻译：本发明包括用于重组肽分子的方法和组合物，包括向肽添加或缺失一个或多个糖基，和/或向肽中加入修饰基团。

3. 发明申请

US20110172688A1 Conduit Harvesting Instrument and Method 审中-公开
标题翻译：管道收获仪器和方法
公开(公告)号：US20110172688A1
公开(公告)日：2011-07-14
申请号：US12685292
申请日：2010-01-11
申请人： Hanspeter Robert Bayer
发明人： Hanspeter Robert Bayer
IPC分类号： A61B17/22
CPC分类号： A61B17/00008
摘要： A surgical instrument for harvesting vessels from the body includes an elongated shaft having distal and proximal ends and a plurality of lumens disposed therethrough. The shaft also includes a tip having a dissecting portion disposed at a distal end thereof and a cradle section. The tip is movable from a first position proximate the distal end of the shaft to at least one additional position distally further from the distal end of the shaft to expose the cradle section. The instrument also includes an endoscope disposed in one of the plurality of lumens and at least one additional surgical instrument disposed in one of the remaining lumens. Methods are disclosed for utilizing the surgical instrument.
摘要翻译：用于从身体收集容器的手术器械包括具有远端和近端的细长轴和设置在其中的多个腔。轴还包括具有设置在其远端处的解剖部分和支架部分的尖端。尖端可从靠近轴的远端的第一位置移动到离轴远端更远的至少一个附加位置，以露出支架部分。仪器还包括设置在多个管腔中的一个腔内的内窥镜和设置在其余腔内之一中的至少一个另外的手术器械。公开了利用外科器械的方法。

4. 发明申请

US20090275952A1 DISTRACTOR 有权
标题翻译：分类器
公开(公告)号：US20090275952A1
公开(公告)日：2009-11-05
申请号：US12115043
申请日：2008-05-05
申请人： Jonathan Lawson , Scott Johnson , Ernest Corraro, JR. , Hanspeter Robert Bayer , Robert H. Humphries, JR.
发明人： Jonathan Lawson , Scott Johnson , Ernest Corraro, JR. , Hanspeter Robert Bayer , Robert H. Humphries, JR.
IPC分类号： A61B17/58
CPC分类号： A61B17/025 , A61B17/0206 , A61B17/1757 , A61B17/7077 , A61B2017/0042 , A61B2017/00915 , A61B2017/0092 , A61B2017/0256 , A61B2090/033 , A61B2090/0807
摘要： An instrument for distracting and/or compressing adjacent vertebrae is described. The instrument includes a yoke, a first blade movably mounted to the yoke, a second blade mounted to the yoke and an adjustment system. The yoke, the first blade and the second blade form a working channel for the instrument. The adjustment system of the instrument is configured to adjust a spacing between the first blade and the second blade by selectively moving the first blade relative to the second blade to distract and/or compress adjacent vertebrae when the first blade and the second blade have been secured to the adjacent vertebrae. The instrument may include a depth stop system that limits an insertion depth of an associated tool inserted into the working channel of the instrument. The adjustable depth stop system includes a releasable catch for securing a stop element of the associated tool. A position of the releasable catch relative to the working channel is adjustable to vary the insertion depth of the associated tool.
摘要翻译：描述了用于分散和/或压缩相邻椎骨的器械。仪器包括轭，可移动地安装到轭的第一刀片，安装到轭的第二刀片和调节系统。轭，第一刀片和第二刀片形成用于仪器的工作通道。该仪器的调节系统配置成通过相对于第二刀片选择性地移动第一刀片以在第一刀片和第二刀片已被固定时分散和/或压缩邻近的椎骨来调节第一刀片和第二刀片之间的间隔到相邻的椎骨。仪器可以包括深度限制系统，其限制插入到仪器的工作通道中的相关工具的插入深度。可调深度止动系统包括用于固定相关联工具的止动元件的可释放的止动件。相对于工作通道的可释放的卡扣的位置是可调节的，以改变相关工具的插入深度。

5. 发明申请

US20090069713A1 Medical Instrument 有权
标题翻译：医疗仪器
公开(公告)号：US20090069713A1
公开(公告)日：2009-03-12
申请号：US12266452
申请日：2008-11-06
申请人： Leland Ray Adams , Frederick Timothy Karl , Hanspeter Robert Bayer , Terence Clifford Johnson
发明人： Leland Ray Adams , Frederick Timothy Karl , Hanspeter Robert Bayer , Terence Clifford Johnson
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B2010/0208
摘要： A medical instrument includes a housing, a stylet having a portion in the housing, a cannula coaxially receiving the stylet and having a portion in the housing, and a member slidably coupled to the housing. The stylet and the cannula are movable between an extended position and a retracted position. The member is configured with first and second bars to move the stylet and the cannula from their extended positions to their retracted positions.
摘要翻译：医疗器械包括壳体，具有壳体中的一部分的探针，同轴地容纳探针并且具有壳体中的一部分的套管以及可滑动地联接到壳体的构件。探针和套管可在延伸位置和缩回位置之间移动。该构件配置有第一和第二杆以将管心针和套管从其延伸位置移动到其缩回位置。

6. 发明授权

US07449000B2 Medical instrument 有权
标题翻译：医疗仪器
公开(公告)号：US07449000B2
公开(公告)日：2008-11-11
申请号：US11325837
申请日：2006-01-04
申请人： Leland Ray Adams , Frederick Timothy Karl , Hanspeter Robert Bayer , Terence Clifford Johnson
发明人： Leland Ray Adams , Frederick Timothy Karl , Hanspeter Robert Bayer , Terence Clifford Johnson
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B2010/0208
摘要： A medical instrument includes a housing, a stylet having a portion in the housing, a cannula coaxially receiving the stylet and having a portion in the housing, and a member slidably coupled to the housing. The stylet and the cannula are movable between an extended position and a retracted position. The member is configured with first and second bars to move the stylet and the cannula from their extended positions to their retracted positions.
摘要翻译：医疗器械包括壳体，具有壳体中的一部分的探针，同轴地容纳探针并且具有壳体中的一部分的套管以及可滑动地联接到壳体的构件。探针和套管可在延伸位置和缩回位置之间移动。该构件配置有第一和第二杆以将管心针和套管从其延伸位置移动到其缩回位置。

7. 发明授权

US07351474B2 Pigment preparations 失效
标题翻译：颜料制剂
公开(公告)号：US07351474B2
公开(公告)日：2008-04-01
申请号：US10416756
申请日：2001-11-15
申请人： Guenter Etzrodt , Achim Grefenstein , Wieland Jenet , Robert Bayer , Reinhold Rieger
发明人： Guenter Etzrodt , Achim Grefenstein , Wieland Jenet , Robert Bayer , Reinhold Rieger
IPC分类号： B32B5/16
CPC分类号： C08J3/212 , B32B27/08 , B32B27/20 , Y10T428/254 , Y10T428/29 , Y10T428/2991 , Y10T428/2998 , Y10T428/31507 , Y10T428/31721 , Y10T428/31725 , Y10T428/31736 , Y10T428/3175 , Y10T428/31786 , Y10T428/31797
摘要： A pigment formulation in granule form obtainable by a) dispersing at least two different pigments (A) in a solution of a thermoplastic polymer (B) in an organic solvent in the presence or absence of a dispersant (C), and b) applying as a layer the dispersion produced in step a) to granules of a thermoplastic polymer (B′), which is the same as the polymer (B), with removal of the solvent, wherein the pigment formulation includes the granules of the thermoplastic polymer (B′); and a coating on the granules of the thermoplastic polymer (B′), where the coating comprises the at least two different pigments (A) and the thermoplastic polymer (B).
摘要翻译：颗粒形式的颜料制剂可通过以下方法获得：a）在有或无分散剂（C）的存在或不存在下，将至少两种不同颜料（A）分散在热塑性聚合物（B）在有机溶剂中的溶液中，和b）在步骤a）中制备的分散体与去除溶剂一起去除与聚合物（B）相同的热塑性聚合物（B'）的颗粒，其中颜料配方包括热塑性聚合物（B '）; 和在热塑性聚合物（B'）的颗粒上的涂层，其中涂层包含至少两种不同的颜料（A）和热塑性聚合物（B）。

8. 发明授权

US07179617B2 Factor IX: remolding and glycoconjugation of Factor IX 有权
标题翻译：因子IX：因子IX的重塑和糖结合
公开(公告)号：US07179617B2
公开(公告)日：2007-02-20
申请号：US10410897
申请日：2003-04-09
申请人： Shawn DeFrees , David Zopf , Robert Bayer , Caryn Bowe , David James Hakes , Xi Chen
发明人： Shawn DeFrees , David Zopf , Robert Bayer , Caryn Bowe , David James Hakes , Xi Chen
IPC分类号： C12P21/06 , A61K35/04
CPC分类号： A61K47/48215 , A61K38/00 , A61K38/37 , A61K47/60 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/755 , C12N9/644 , C12N9/96 , Y02A50/472
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
摘要翻译：本发明包括用于重组肽分子的方法和组合物，包括向肽添加或缺失一个或多个糖基，和/或向肽中加入修饰基团。

9. 发明授权

US07157277B2 Factor VIII remodeling and glycoconjugation of Factor VIII 有权
标题翻译：因子VIII因子VIII重塑和糖结合
公开(公告)号：US07157277B2
公开(公告)日：2007-01-02
申请号：US10410997
申请日：2003-04-09
申请人： Shawn DeFrees , David Zopf , Robert Bayer , Caryn Bowe , David Hakes , Xi Chen
发明人： Shawn DeFrees , David Zopf , Robert Bayer , Caryn Bowe , David Hakes , Xi Chen
IPC分类号： C12N5/06 , C07K1/00
CPC分类号： C07K1/006 , A61K38/00 , A61K47/60 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/755 , Y02A50/472
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
摘要翻译：本发明包括用于重组肽分子的方法和组合物，包括向肽添加或缺失一个或多个糖基，和/或向肽中加入修饰基团。

10. 发明申请

US20060287224A1 Glycopegylated erythropoietin formulations 有权
标题翻译：糖基化促红细胞生成素制剂
公开(公告)号：US20060287224A1
公开(公告)日：2006-12-21
申请号：US11440839
申请日：2006-05-25
申请人： Shawn DeFrees , Robert Bayer , David Zopf , Jichao Kang , Walter Willett
发明人： Shawn DeFrees , Robert Bayer , David Zopf , Jichao Kang , Walter Willett
IPC分类号： A61K38/16
CPC分类号： C07K14/505 , A61K38/1816 , A61K47/549 , A61K47/60
摘要： The present invention provides conjugates between erythropoietin and PEG moieties. The conjugates are linked via an intact glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto a glycosyl residue on the peptide. Also provided are methods for preparing the conjugates, methods for treating various disease conditions with the conjugates, and pharmaceutical formulations including the conjugates.
摘要翻译：本发明提供红细胞生成素和PEG部分之间的缀合物。缀合物通过插入和共价连接到肽和修饰基团之间的完整糖基连接基团连接。通过糖基转移酶的作用，由糖基化肽形成缀合物。糖基转移酶将修饰的糖部分连接到肽上的糖基残基上。还提供了制备缀合物的方法，用缀合物治疗各种疾病状况的方法，以及包括缀合物的药物制剂。

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