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1. 发明专利

TW201510380A 緊固件及安裝緊固件之方法审中-公开
简体标题：紧固件及安装紧固件之方法
公开(公告)号：TW201510380A
公开(公告)日：2015-03-16
申请号：TW103121618
申请日：2014-06-23
申请人：普拉特約翰D , PRATT, JOHN D.
发明人：普拉特約翰D , PRATT, JOHN D.
IPC分类号： F16B39/04 , F16B39/08 , F16B13/06
CPC分类号： F16B19/1072 , F16B19/1063
摘要：本發明係關於一種緊固件，其包括一主體，該主體具有一第一末端上之一放大頭部、一第二末端上之一錐形斜面、安置在該放大頭部與該錐形斜面之間之一圓柱形柄及在該第一末端與該第二末端之間延伸且包含螺紋之一通道。該緊固件進一步包含一大致圓柱形芯型螺栓，該芯型螺栓被安置在該主體之該通道內且具有一放大頭部、一分離凹槽、及一止擋肩部，該止擋肩部經組態以在該分離凹槽與該放大頭部之一外表面實質平齊時導致對將該芯型螺栓螺接至該主體中之阻力之一突增。一夾緊補償器被安置在該芯型螺栓上與該芯型螺栓之該放大頭部鄰接。一可變形套管被可移動地安置在該芯型螺栓之一部分上方且被安置在該夾緊補償器與該主體之該錐形斜面之間。
简体摘要：本发明系关于一种紧固件，其包括一主体，该主体具有一第一末端上之一放大头部、一第二末端上之一锥形斜面、安置在该放大头部与该锥形斜面之间之一圆柱形柄及在该第一末端与该第二末端之间延伸且包含螺纹之一信道。该紧固件进一步包含一大致圆柱形芯型螺栓，该芯型螺栓被安置在该主体之该信道内且具有一放大头部、一分离凹槽、及一止挡肩部，该止挡肩部经组态以在该分离凹槽与该放大头部之一外表面实质平齐时导致对将该芯型螺栓螺接至该主体中之阻力之一突增。一夹紧补偿器被安置在该芯型螺栓上与该芯型螺栓之该放大头部邻接。一可变形套管被可移动地安置在该芯型螺栓之一部分上方且被安置在该夹紧补偿器与该主体之该锥形斜面之间。

2. 发明公开

EP2647851A1 Fastener and method of installing same 有权
标题翻译：紧固件和安装方法
公开(公告)号：EP2647851A1
公开(公告)日：2013-10-09
申请号：EP13001652.0
申请日：2013-03-29
申请人： Pratt, John D.
发明人： Pratt, John D.
IPC分类号： F16B19/10
CPC分类号： F16B19/1063 , Y10T29/49956
摘要： A fastener includes a body (20) having deformable first end (32), a second end (34), and a passage (22) extending through the body (20) between the first and second ends (32, 34). The fastener further includes a corebolt (50) having first and second ends (54,60) and a region of reduced diameter (64) disposed between the first and second ends (54, 60) and a sleeve (70) having first and second ends (72, 74), the second end (74) having a bulbing portion (80), The corebolt (50) is disposed within the sleeve (70) and the body (20) with the first end (54) of the corebolt (50) in engagement with the first end (72) of the sleeve (70) and the first end (32) of the body (20) disposed adjacent the second end (74) of the sleeve (70). The bulbing portion (80) is adapted to form an enlarged blind head when the corebolt (50) is rotated in relation to the sleeve (70). The first end (32) of the body (20) is adapted to deform radially inwardly into the region of reduced diameter (64).

3. 发明授权

EP2647851B1 Fastener and method of installing same 有权
标题翻译：紧固件和安装方法
公开(公告)号：EP2647851B1
公开(公告)日：2017-06-14
申请号：EP13001652.0
申请日：2013-03-29
申请人： Pratt, John D.
发明人： Pratt, John D.
IPC分类号： F16B19/10
CPC分类号： F16B19/1063 , Y10T29/49956

4. 发明申请

WO2015002770A2 FASTENER AND METHOD OF INSTALLING SAME 审中-公开
标题翻译：紧固件和安装方法
公开(公告)号：WO2015002770A2
公开(公告)日：2015-01-08
申请号：PCT/US2014/043850
申请日：2014-06-24
申请人： PRATT, John D.
发明人： PRATT, John D.
IPC分类号： F16B29/00
CPC分类号： F16B19/1072 , F16B19/1063
摘要： A fastener comprises a body having an enlarged head at a first end, a tapered ramp at a second end, a cylindrical shank disposed between the enlarged head and the tapered ramp, and a passage extending between the first and second ends and including threads. The fastener further includes a generally cylindrical corebolt disposed within the passage of the body and having an enlarged head, a breaking groove, and a stop shoulder that is configured to cause an abrupt increase in resistance to threading the corebolt into the body when the breaking groove is substantially flush with an outer surface of the enlarged head. A grip compensator is disposed on the corebolt in abutment with the enlarged head of the corebolt. A deformable sleeve is movably disposed over a portion of the corebolt and disposed between the grip compensator and the tapered ramp of the body.
摘要翻译：紧固件包括主体，所述主体在第一端处具有扩大的头部，在第二端部处具有锥形坡道，设置在扩大的头部和锥形坡道之间的圆柱形杆以及在第一端部和第二端部之间延伸的通道，和第二端并包括螺纹。所述紧固件还包括布置在所述本体的所述通道内并且具有扩大的头部，断裂槽和止动肩的大致圆柱形的心轴螺栓，所述止动肩被配置为当所述断裂凹槽穿过所述心脏螺栓时，基本与扩大头部的外表面齐平。在芯棒上放置一个夹紧补偿器，与芯棒螺栓的扩大头相邻接。可变形的套筒可移动地设置在芯部螺栓的一部分上并且设置在手柄补偿器和主体的锥形斜面之间。

5. 发明申请

WO2013097052A1 BROMODOMAIN INHIBITORS 审中-公开
标题翻译： BROMODOMAIN抑制剂
公开(公告)号：WO2013097052A1
公开(公告)日：2013-07-04
申请号：PCT/CN2011/002224
申请日：2011-12-30
申请人： ABBOTT LABORATORIES , ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD. , WANG, Le , PRATT, John, K. , MCDANIEL, Keith, F.
发明人： WANG, Le , PRATT, John, K. , MCDANIEL, Keith, F.
IPC分类号： C07D471/04 , C07D487/04 , A61K31/437 , A61K31/495 , A61P35/00 , A61P11/06 , A61P17/00 , A61P1/16 , A61P13/12 , A61P1/02 , A61P17/06 , A61P1/18 , A61P37/06 , A61P3/10
CPC分类号： A61K31/541 , A61K31/437 , A61K31/5025 , A61K31/5377 , A61K45/06 , C07D471/04 , C07D487/04
摘要： Provided are compounds of formula (I), wherein A 1 , A 2 , A 3 , A 4 , X 1 , X 2 , Y 1 , L 1 , G 1 , R x , and R y have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
摘要翻译：提供式（I）的化合物，其中A1，A2，A3，A4，X1，X2，Y1，L1，G1，Rx和Ry具有说明书中定义的任何值及其药学上可接受的盐，可用作治疗疾病和病症（包括炎性疾病，癌症和AIDS）的药物。还提供了包含一种或多种式（I）化合物的药物组合物。

6. 发明申请

WO2010111436A3 ANTIVIRAL COMPOUNDS AND USES THEREOF 审中-公开
标题翻译：有害化合物及其用途
公开(公告)号：WO2010111436A3
公开(公告)日：2011-04-07
申请号：PCT/US2010028560
申请日：2010-03-25
申请人： ABBOTT LAB , BETEBENNER DAVID A , PRATT JOHN K , DEGOEY DAVID A , DONNER PAMELA L , FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , KATI WARREN M , KRUEGER ALLAN C , LONGENECKER KENTON L , MARING CLARENCE J , RANDOLPH JOHN T , ROCKWAY TODD W , TUFANO MICHAEL D , WAGNER ROLF
发明人： BETEBENNER DAVID A , PRATT JOHN K , DEGOEY DAVID A , DONNER PAMELA L , FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , KATI WARREN M , KRUEGER ALLAN C , LONGENECKER KENTON L , MARING CLARENCE J , RANDOLPH JOHN T , ROCKWAY TODD W , TUFANO MICHAEL D , WAGNER ROLF
IPC分类号： C07C15/58 , A61K31/4412 , A61K31/513 , A61P31/14 , C07D207/27 , C07D213/64 , C07D233/32 , C07D233/74 , C07D239/10 , C07D239/54 , C07D263/22 , C07D275/02 , C07D403/10 , C07D405/10 , C07D409/10
CPC分类号： C07D409/10 , A61K31/18 , A61K31/27 , A61K31/402 , A61K31/4166 , A61K31/421 , A61K31/425 , A61K31/4418 , A61K31/503 , A61K31/513 , A61K45/06 , C07C311/08 , C07D207/27 , C07D213/64 , C07D233/32 , C07D233/72 , C07D239/10 , C07D239/54 , C07D263/22 , C07D263/24 , C07D275/02 , C07D403/10 , C07D405/10 , Y02P20/55
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
摘要翻译：本发明涉及：（a）特别是抑制HCV的化合物及其盐; （b）可用于制备这些化合物和盐的中间体; （c）包含这些化合物和盐的组合物; （d）制备这种中间体，化合物，盐和组合物的方法; （e）使用这些化合物，盐和组合物的方法; 和（f）包含这些化合物，盐和组合物的试剂盒。

7. 发明申请

WO2010111593A3 BLIND BOLT FASTENER 审中-公开
标题翻译：黑色螺栓紧固件
公开(公告)号：WO2010111593A3
公开(公告)日：2011-01-13
申请号：PCT/US2010028832
申请日：2010-03-26
申请人： MONOGRAM AEROSPACE FASTENERS INC , PRATT JOHN D
发明人： PRATT JOHN D
IPC分类号： F16B19/10 , F16B5/02 , F16B5/04 , F16B23/00 , F16B35/06
CPC分类号： F16B19/1045 , F16B5/04 , Y10T29/49948
摘要： Disclosed is a blind bolt fastener that includes a threaded nut and bolt combination that passes through a deformable sleeve that has a shoulder, a deformable portion and a non-deformable portion. Upon tightening of the threaded bolt and nut combination, the deformable portion is compressed so that it bulbs to form a bulbed head. The shoulder on the sleeve blocks further compression of the deformable portion once the bulbed head is substantially completely formed.
摘要翻译：公开了一种盲螺栓紧固件，其包括穿过具有肩部，可变形部分和不可变形部分的可变形套筒的螺纹螺母和螺栓组合。在拧紧螺栓和螺母组合时，可变形部分被压缩，使得其变亮以形成凸起的头部。一旦突出的头部基本上完全形成，套筒上的肩部阻挡可变形部分的进一步压缩。

8. 发明申请

WO2010144646A2 ANTI-VIRAL COMPOUNDS 审中-公开
标题翻译：反虚构化合物
公开(公告)号：WO2010144646A2
公开(公告)日：2010-12-16
申请号：PCT/US2010038077
申请日：2010-06-10
申请人： ABBOTT LAB , DEGOEY DAVID A , KATI WARREN M , HUTCHINS CHARLES W , DONNER PAMELA L , KRUEGER ALLAN C , RANDOLPH JOHN T , MOTTER CHRISTOPHER E , NELSON LISSA T , PATEL SACHIN V , MATULENKO MARK A , KEDDY RYAN G , JINKERSON TAMMIE K , SOLTWEDEL TODD N , HUTCHINSON DOUGLAS K , FLENTGE CHARLES A , WAGNER ROLF , MARING CLARENCE J , TUFANO MICHAEL D , BETEBENNER DAVID A , ROCKWAY TODD W , LIU DACHUN , PRATT JOHN K , LAVIN MICHAEL J , SARRIS KATHY , WOLLER KEVIN R , WAGAW SEBLE H , CALIFANO JEAN C , LI WENKE
发明人： DEGOEY DAVID A , KATI WARREN M , HUTCHINS CHARLES W , DONNER PAMELA L , KRUEGER ALLAN C , RANDOLPH JOHN T , MOTTER CHRISTOPHER E , NELSON LISSA T , PATEL SACHIN V , MATULENKO MARK A , KEDDY RYAN G , JINKERSON TAMMIE K , SOLTWEDEL TODD N , HUTCHINSON DOUGLAS K , FLENTGE CHARLES A , WAGNER ROLF , MARING CLARENCE J , TUFANO MICHAEL D , BETEBENNER DAVID A , ROCKWAY TODD W , LIU DACHUN , PRATT JOHN K , LAVIN MICHAEL J , SARRIS KATHY , WOLLER KEVIN R , WAGAW SEBLE H , CALIFANO JEAN C , LI WENKE
IPC分类号： C07D403/14
CPC分类号： C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
摘要： Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
摘要翻译：描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。

9. 发明申请

WO2009146058A2 FLUSH-MOUNT, BLIND FASTENER 审中-公开
标题翻译： FLUSH-MOUNT，BLIND紧固件
公开(公告)号：WO2009146058A2
公开(公告)日：2009-12-03
申请号：PCT/US2009/039083
申请日：2009-04-01
申请人： MONOGRAM AEROSPACE FASTENERS, INC. , TAMASHIRO, Emory, K. , PRATT, John, D.
发明人： TAMASHIRO, Emory, K. , PRATT, John, D.
IPC分类号： F16B13/04 , F16B13/06
CPC分类号： F16B19/1063 , F16B19/1072 , Y10T29/49947
摘要： A threaded blind fastener intended for installation in aerodynamically smooth or aesthetically critical panels, further adapted to minimize discontinuities on paintable surfaces of the head resulting from clearances between male and female threads that may adversely affect the quality of paint coverage.
摘要翻译：一种用于安装在空气动力学平滑或美观临界面板中的螺纹盲紧固件，其进一步适于最小化可能对涂层覆盖质量产生不利影响的阳螺纹和阴螺纹之间的间隙的头部可涂漆表面上的不连续性。

10. 发明申请

WO2009039134A1 ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF 审中-公开
标题翻译：抗感染性吡啶类及其用途
公开(公告)号：WO2009039134A1
公开(公告)日：2009-03-26
申请号：PCT/US2008/076592
申请日：2008-09-17
申请人： ABBOTT LABORATORIES , FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , BETEBENNER, David, A. , DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , KRUEGER, Allan, C. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton, L. , MARING, Clarence, J. , MOTTER, Christopher, E. , PRATT, John, K. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , STEWART, Kent, D. , WAGNER, Rolf , BARNES, David, M. , CHEN, Shuang , FRANCZYK, Thaddeus, S., II , GAO, Yi , HAIGHT, Anthony, R. , HENGEVELD, John, E. , KOTECKI, Brian, J. , LOU, Xiaochun , ZHANG, Geoff, G., Z.
发明人： FLENTGE, Charles, A. , HUTCHINSON, Douglas, K. , BETEBENNER, David, A. , DEGOEY, David, A. , DONNER, Pamela, L. , KATI, Warren, M. , KRUEGER, Allan, C. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton, L. , MARING, Clarence, J. , MOTTER, Christopher, E. , PRATT, John, K. , RANDOLPH, John, T. , ROCKWAY, Todd, W. , STEWART, Kent, D. , WAGNER, Rolf , BARNES, David, M. , CHEN, Shuang , FRANCZYK, Thaddeus, S., II , GAO, Yi , HAIGHT, Anthony, R. , HENGEVELD, John, E. , KOTECKI, Brian, J. , LOU, Xiaochun , ZHANG, Geoff, G., Z.
IPC分类号： C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K31/513 , A61P31/12
CPC分类号： C07D239/54 , A61K31/513 , A61K45/06 , C07D239/22 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , A61K2300/00
摘要： This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
摘要翻译：本发明涉及：（a）特别是抑制HCV的化合物及其盐; （b）可用于制备这些化合物和盐的中间体; （c）包含这些化合物和盐的组合物; （d）制备这种中间体，化合物，盐和组合物的方法; （e）使用这些化合物，盐和组合物的方法; 和（f）包含这些化合物，盐和组合物的试剂盒。

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