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    • 1. 发明申请
    • HIGH QUALITY NON-POLAR/SEMI-POLAR SEMICONDUCTOR ELEMENT ON TILT SUBSTRATE AND FABRICATION METHOD THEREOF
    • 高品质非极性半极半导体元件及其制造方法
    • WO2011025290A3
    • 2011-06-30
    • PCT/KR2010005762
    • 2010-08-27
    • SEOUL OPTO DEVICE CO LTDKOREA POLYTECH UNIV IND ACADNAM OK HYUNJANG JONG JIN
    • NAM OK HYUNJANG JONG JIN
    • H01L33/02
    • H01L33/16H01L33/007H01L33/32
    • The present invention relates to a high quality non-polar/semi-polar semiconductor element and a fabrication method thereof, wherein a nitride semiconductor crystal is formed on a sapphire crystal plane that enables the growth of a non-polar/semi-polar nitride semiconductor layer to eliminate an piezoelectric effect; and a template layer is formed on a corresponding off-axis of the sapphire crystal plane tilted in a predetermined direction to reduce the defect density of the semiconductor element and improves the internal quantum efficiency and extraction efficiency. In the fabrication method of a semiconductor element by forming a template layer and a semiconductor element structure on the sapphire substrate having a crystal plane for the growth of a non-polar or semi-polar nitride semiconductor layer, the sapphire substrate is a substrate having the crystal plane tilted in a predetermined direction, and a nitride semiconductor layer and the template layer comprising a GaN layer are formed on the tilt substrate.
    • 本发明涉及一种高品质非极性/半极性半导体元件及其制造方法,其中氮化物半导体晶体形成在蓝宝石晶体平面上,其能够生长非极性/半极性氮化物半导体 层消除压电效应; 并且在规定方向倾斜的蓝宝石晶面的对应偏轴上形成模板层,以降低半导体元件的缺陷密度,提高内部量子效率和提取效率。 在通过在具有用于生长非极性或半极性氮化物半导体层的晶面的蓝宝石衬底上形成模板层和半导体元件结构的半导体元件的制造方法中,蓝宝石衬底是具有 晶面在预定方向上倾斜,并且氮化物半导体层和包括GaN层的模板层形成在倾斜衬底上。
    • 3. 发明申请
    • SUBSTITUTED BENZODIAZEPINONES, BENZOXAZEPINONES AND BENZOTHIAZEPINONES AS SODIUM CHANNEL BLOCKERS
    • 作为钠通道阻断剂的取代苯并恶嗪酮,苯并恶唑酮和苯并噻唑酮
    • WO2008106077A1
    • 2008-09-04
    • PCT/US2008/002441
    • 2008-02-25
    • MERCK & CO., INC.HOYT, Scott, B.OK, DongOK, Hyun, O.LONDON, ClareDUFFY, Joseph, L.
    • HOYT, Scott, B.OK, DongOK, Hyun, O.LONDON, ClareDUFFY, Joseph, L.
    • A01N43/62A61K31/55
    • C07D281/10C07D245/06C07D267/14
    • The present invention is directed to substituted benzodiazepinones, benzoxazepinones and benzothiazepinones compounds that are sodium channel blockers useful for the treatment of chronic and neuropathic pain. The compounds of the present invention are also useful for the treatment of other conditions, including disorders of the CNS such as anxiety, depression, epilepsy, manic depression and bipolar disorder. This invention also provides pharmaceutical compositions comprising a compound of the present invention, either alone, or in combination with one or more therapeutically active compounds, and a pharmaceutically acceptable carrier. This invention further comprises methods for the treatment of acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain and disorders of the CNS including, but not limited to, epilepsy, manic depression, depression, anxiety and bipolar disorder comprising administering the compounds and pharmaceutical compositions of the present invention.
    • 本发明涉及用作治疗慢性和神经性疼痛的钠通道阻滞剂的取代苯并二氮杂酮,苯并氧氮杂酮和苯并噻唑酮化合物。 本发明的化合物还可用于治疗其他病症,包括CNS的疾病如焦虑症,抑郁症,癫痫症,躁狂抑郁症和双相性精神障碍。 本发明还提供包含单独的或与一种或多种治疗活性化合物组合的本发明化合物和药学上可接受的载体的药物组合物。 本发明还包括用于治疗急性疼痛,慢性疼痛,内脏痛,炎性疼痛,神经性疼痛和中枢神经系统疾病的方法,包括但不限于癫痫症,躁狂抑郁症,抑郁症,焦虑和双相情感障碍,包括给予化合物 和本发明的药物组合物。