专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2010011865A Cell having dna insertional mutation for forming polypeptide of modified amount 审中-公开
标题翻译：具有形成改性金属多肽的DNA插入突变的细胞
公开(公告)号：JP2010011865A
公开(公告)日：2010-01-21
申请号：JP2009216933
申请日：2009-09-18
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： BRODY HOWARD , YAVER DEBORAH S , LAMSA MICHAEL H , HANSEN KIM
IPC分类号： C12N15/09 , C12P21/02 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/20 , C12N9/42 , C12N15/67 , C12N15/80
CPC分类号： C12N9/2434 , C12N9/20 , C12N15/67 , C12N15/80 , C12P21/02 , C12Y302/01004
摘要： PROBLEM TO BE SOLVED: To provide a new method for modifying the production of a polypeptide. SOLUTION: This method for modifying the production of the polypeptide comprises (a) the introduction of a nucleic acid construct into a cell containing a DNA sequence for encoding the polypeptide so as to produce a mutant cell by the nucleic acid construct under a condition that the nucleic acid construct is integrated into the genom of the cell at a gene locus not within the DNA sequence encoding the above polypeptide, and in the case that the mutant cells and parent cells are cultured under a same condition, the integration of the nucleic acid modifies the production of the polypeptide by the mutant cells relative to the parent cells, and (b) the identification of the mutant cells having the modified production of the polypeptide. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种修饰多肽生产的新方法。解决方案：用于修饰多肽的产生的该方法包括（a）将核酸构建体引入到含有用于编码多肽的DNA序列的细胞中，以便通过核酸构建体产生突变细胞，条件是将核酸构建体整合到编码上述多肽的DNA序列内的基因座处的细胞基因组中，并且在突变细胞和亲代细胞在相同条件下培养的情况下，核酸通过突变体细胞相对于亲本细胞修饰多肽的产生，和（b）具有修饰的多肽产生的突变细胞的鉴定。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2009131277A Method for producing polypeptide in bacillus cell 有权
标题翻译：用于在玻璃体细胞中生产多肽的方法
公开(公告)号：JP2009131277A
公开(公告)日：2009-06-18
申请号：JP2009059814
申请日：2009-03-12
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： WIDNER WILLIAM , SLOMA ALAN , THOMAS MICHAEL D
IPC分类号： C12N15/09 , C07K14/325 , C12N1/21 , C12N9/54 , C12N15/32 , C12N15/75 , C12P21/02 , C12R1/07
CPC分类号： C12N15/75
摘要： PROBLEM TO BE SOLVED: To provide a new method for producing a polypeptide in bacillus. SOLUTION: Provided are methods for producing a polypeptide, comprising: (a) cultivating a Bacillus host cell in a medium conducive for the production of the polypeptide, wherein the Bacillus cell comprises a tandem promoter in which each promoter sequence of the tandem promoter is operably linked to a nucleic acid sequence encoding the polypeptide and if required (ii) a nucleic acid construct comprising an mRNA processing/stabilizing sequence located downstream of the tandem promoter and upstream of the nucleic acid sequence encoding the polypeptide; and (b) isolating the polypeptide from the cultivation medium. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供一种用于在杆菌中产生多肽的新方法。提供了用于产生多肽的方法，其包括：（a）在有助于产生多肽的培养基中培养芽孢杆菌宿主细胞，其中芽孢杆菌细胞包含串联启动子，其中串联的每个启动子序列启动子可操作地连接到编码多肽的核酸序列，如果需要（ii）包含位于串联启动子下游的mRNA加工/稳定序列和编码该多肽的核酸序列上游的核酸构建体; 和（b）从培养基中分离多肽。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP2013121361A Promoter for expressing gene in fungal cell 审中-公开
标题翻译：用于在真菌细胞中表达基因的促进剂
公开(公告)号：JP2013121361A
公开(公告)日：2013-06-20
申请号：JP2013021169
申请日：2013-02-06
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： BERKA RANDY M , REY MICHAEL W , BROWN KIMBERLY , BROWN STEPHEN H
IPC分类号： C12N15/09 , C07K14/37 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/34 , C12N15/80 , C12P21/02
CPC分类号： C12N9/2428 , C07K14/37 , C12N15/80
摘要： PROBLEM TO BE SOLVED: To provide a new method for producing a polypeptide.SOLUTION: The method for producing a polypeptide includes (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of specific sequence, a subsequence thereof and hybrid and tandem promoters thereof and (b) isolating the polypeptide from the cultivation medium.
摘要翻译：待解决的问题：提供生产多肽的新方法。解决方案：用于产生多肽的方法包括（a）在有助于产生多肽的培养基中培养真菌宿主细胞，其中真菌宿主细胞包含编码多肽的第一核酸序列，其可操作地连接到第二个包含核酸序列外源的启动子的核酸序列，其中所述启动子包含选自特定序列，其子序列及其杂交和串联启动子的序列，和（b）从培养基中分离多肽。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2013121360A Promoter for expressing gene in fungal cell 审中-公开
标题翻译：用于在真菌细胞中表达基因的促进剂
公开(公告)号：JP2013121360A
公开(公告)日：2013-06-20
申请号：JP2013021124
申请日：2013-02-06
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： BERKA RANDY M , REY MICHAEL W , BROWN KIMBERLY , BROWN STEPHEN H
IPC分类号： C12N15/09 , C07K14/37 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/26 , C12N9/34 , C12N15/80 , C12P21/02
CPC分类号： C12N9/2428 , C07K14/37 , C12N15/80
摘要： PROBLEM TO BE SOLVED: To provide a new method for producing a polypeptide.SOLUTION: The method for producing a polypeptide includes (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of specific nucleotides 1 to 3,949, nucleotides 1 to 938, and nucleotides 1 to 3,060 and a subsequence thereof and hybrid and tandem promoters thereof and (b) isolating the polypeptide from the cultivation medium.
摘要翻译：待解决的问题：提供生产多肽的新方法。解决方案：用于产生多肽的方法包括（a）在有助于产生多肽的培养基中培养真菌宿主细胞，其中真菌宿主细胞包含编码多肽的第一核酸序列，其可操作地连接到第二个核酸序列，其包含核酸序列异源的启动子，其中所述启动子包含选自特异性核苷酸1至3949，核苷酸1至938和核苷酸1至3,060及其亚序列的杂交和串联启动子和（b）从培养基中分离多肽。版权所有（C）2013，JPO＆INPIT

5. 发明专利

JP2005341973A Thermophilic fungal expression system 有权
标题翻译：热绝缘真菌表达系统
公开(公告)号：JP2005341973A
公开(公告)日：2005-12-15
申请号：JP2005238334
申请日：2005-08-19
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： JENSEN EJNER B , BOOMINATHAN KARUPPAN C
IPC分类号： C12N15/09 , C12N1/14 , C12N1/15 , C12N9/02 , C12N9/10 , C12N9/14 , C12N9/24 , C12N9/88 , C12N9/90 , C12N15/55 , C12N15/80 , C12R1/645 , C12R1/69 , C12R1/75
CPC分类号： C12N9/248 , C12N15/80 , Y10S435/911
摘要： PROBLEM TO BE SOLVED: To provide a novel expression system regarding a host cell useful for production of a recombinant protein, especially a thermophilic fungal host cell which can be used in the expression of recombinant proteins, especially enzymes.
SOLUTION: Disclosed is a recombinant thermophilic fungal host cell comprising a nucleic acid sequence encoding a heterologous protein and characterized by being a member of Acremonium.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供关于可用于生产重组蛋白质，特别是可用于表达重组蛋白质，特别是酶的嗜热真菌宿主细胞的宿主细胞的新型表达系统。解决方案：公开了一种重组嗜热真菌宿主细胞，其包含编码异源蛋白质的核酸序列，其特征在于是顶孢属成员。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2011206058A Polypeptide having cellulolytic enhancing activity and polynucleotide encoding the same 有权
标题翻译：具有纤维素增强活性的多肽和编码其的多核苷酸
公开(公告)号：JP2011206058A
公开(公告)日：2011-10-20
申请号：JP2011124595
申请日：2011-06-02
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： DOTSON WILLIAM , GREENIER JENNIFER , DING HANSHU
IPC分类号： C12N15/09 , C07K14/195 , C11D3/386 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/42 , C12N15/82 , C12P3/00 , C12P5/00 , C12P7/10 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/50 , C12P7/52 , C12P7/54 , C12P7/56 , C12P7/58 , C12P13/04 , C12P13/08 , C12P13/14 , C12P13/20 , C12P21/02
CPC分类号： C07K14/37 , C11D3/38645 , C12N9/2445 , C12N15/8246 , C12P7/10 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： PROBLEM TO BE SOLVED: To provide isolated polypeptides having cellulolytic enhancing activity.SOLUTION: There are provided: the isolated polypeptides having cellulolytic enhancing activity; isolated nucleic acids encoding the polypeptides; nucleic acid constructs, vectors, and host cells comprising the nucleic acids; methods for producing the polypeptides; and methods for producing an organic substance, comprising saccharifying a cellulosic material with an effective amount of a cellulolytic protein in the presence of an effective amount of the polypeptide, fermenting the saccharified cellulosic material with one or more fermenting microorganisms, and recovering the organic substance.
摘要翻译：要解决的问题：提供具有纤维素分解增强活性的分离的多肽。解决方案：提供：具有纤维素分解增强活性的分离的多肽; 编码多肽的分离的核酸; 核酸构建体，载体和包含核酸的宿主细胞; 生产多肽的方法; 以及生产有机物质的方法，包括在有效量的多肽的存在下用有效量的纤维素分解蛋白质糖化纤维素材料，用一种或多种发酵微生物发酵糖化的纤维素材料，并回收有机物质。

7. 发明专利

JP2009159979A Aspergillus porphobilinogen synthase and nucleic acid encoding the same 审中-公开
标题翻译： ASPERGILLUS PORPHOBILINOGEN SYNTHASE AND NUCLEIC ACID ENCODING THE SAME
公开(公告)号：JP2009159979A
公开(公告)日：2009-07-23
申请号：JP2009059788
申请日：2009-03-12
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： JONES AUBREY , CHERRY JOEL R
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N9/10 , C12N9/88 , C12N15/60
CPC分类号： C12N9/1029 , C12N9/88
摘要： PROBLEM TO BE SOLVED: To provide an Aspergillus porphobilinogen synthase and an isolated nucleic acid fragment comprising nucleic acid sequence encoding the porphobilinogen synthase as well as a nucleic acid construct, a vector, and a recombinant host cell comprising the nucleic acid sequence and to provide a method of producing the porphobilinogen synthase. SOLUTION: The porphobilinogen synthase (a) has a specific amino acid sequence; or (b) has an amino acid sequence in which 1, 2 or 3 amino acids are inserted, removed or substituted in a specific amino acid sequence represented by sequence No. 2; or (c) is encoded by a nucleic acid sequence hybridizable under the same conditions by using a probe hybridized with a specific nucleic acid sequence under high stringent conditions. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供曲霉菌素原合成酶和包含编码胆色素原合成酶的核酸序列的分离的核酸片段以及包含核酸序列的核酸构建体，载体和重组宿主细胞，以提供生成胆色素原合成酶的方法。解决方案：胆色素原合成酶（a）具有特定的氨基酸序列; 或（b）具有氨基酸序列，其中1,2或3个氨基酸以序列号2表示的特定氨基酸序列插入，除去或取代; 或（c）由可在相同条件下杂交的核酸序列编码，通过在高严格条件下使用与特异性核酸序列杂交的探针。版权所有（C）2009，JPO＆INPIT

8. 发明专利

JP2005333996A Thermophilic fungal expression system 有权
标题翻译：热绝缘真菌表达系统
公开(公告)号：JP2005333996A
公开(公告)日：2005-12-08
申请号：JP2005238223
申请日：2005-08-19
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： JENSEN EJNER B , BOOMINATHAN KARUPPAN C
IPC分类号： C12N15/09 , C12N1/14 , C12N1/15 , C12N9/02 , C12N9/10 , C12N9/14 , C12N9/24 , C12N9/88 , C12N9/90 , C12N15/55 , C12N15/80 , C12R1/645 , C12R1/69 , C12R1/75
CPC分类号： C12N9/248 , C12N15/80 , Y10S435/911
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a heterologous protein of interest comprising culturing host cells under the condition inducing expression of the heterologous protein and collecting the heterologous protein from the culture.
SOLUTION: A recombinant thermophilic fugal host cell is characterized by being a member of Sporotrichum comprising a nucleic acid sequence encoding a heterologous protein.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供产生感兴趣的异源蛋白质的方法，包括在诱导异源蛋白质表达的条件下培养宿主细胞并从培养物中收集异源蛋白质。解决方案：重组嗜热矮人宿主细胞的特征在于是包含编码异源蛋白质的核酸序列的孢子菌属的成员。版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2013215208A Polypeptide having lipase activity and polynucleotide encoding the same 审中-公开
标题翻译：具有脂酶活性的多肽和编码其的多核苷酸
公开(公告)号：JP2013215208A
公开(公告)日：2013-10-24
申请号：JP2013141569
申请日：2013-07-05
申请人： Novozyme As , ノボザイムスアクティーゼルスカブ , Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： VIND JESPER , BORCH KIM , MIKKELSEN MIKAEL , KNOTZEL JURGEN CARSTEN FRANZ
IPC分类号： C12N15/09 , C07K14/195 , C07K14/37 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/20 , C12P21/02 , C12R1/01 , C12R1/645
CPC分类号： C12N9/20
摘要： PROBLEM TO BE SOLVED: To provide a lipase variant having improved properties.SOLUTION: The present invention relates to polypeptides having lipase activity and further having an RP (average relative performance) of at least 0.8 and a BR (benefit-risk) of at least 1.1 at the test conditions given in the specification.
摘要翻译：要解决的问题：提供具有改善的性质的脂肪酶变体。解决方案：本发明涉及具有脂肪酶活性并进一步具有至少0.8的RP（平均相对性能）和至少至少的BR（益处 - 风险））的多肽 1.1在规范中给出的测试条件。

10. 发明专利

JP2005333995A Thermophilic fungal expression system 有权
标题翻译：热绝缘真菌表达系统
公开(公告)号：JP2005333995A
公开(公告)日：2005-12-08
申请号：JP2005238219
申请日：2005-08-19
申请人： Novozymes Inc , ノボザイムス,インコーポレイティド
发明人： JENSEN EJNER B , BOOMINATHAN KARUPPAN C
IPC分类号： C12N15/09 , C12N1/14 , C12N1/15 , C12N9/02 , C12N9/10 , C12N9/14 , C12N9/24 , C12N9/88 , C12N9/90 , C12N15/55 , C12N15/80 , C12R1/645 , C12R1/69 , C12R1/75
CPC分类号： C12N9/248 , C12N15/80 , Y10S435/911
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a heterologous protein of interest comprising culturing host cells under the condition inducing expression of the heterologous protein and collecting the heterologous protein from the culture.
SOLUTION: A recombinant thermophilic fugal host cell is characterized by being a member of Myceliophthora comprising a nucleic acid sequence encoding a heterologous protein.
COPYRIGHT: (C)2006,JPO&NCIPI

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式