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1. 发明申请

US20170036788A1 APPARATUS AND METHOD FOR FILLING AND RESEALING 审中-公开
标题翻译：装置和方法用于填充和回收
公开(公告)号：US20170036788A1
公开(公告)日：2017-02-09
申请号：US15333506
申请日：2016-10-25
申请人： MEDINSTILL DEVELOPMENT LLC
发明人： Daniel Py , Benoit Adamo , John Guthy
IPC分类号： B65B7/16 , B65B37/06 , B65B43/54 , B65B55/08 , B65B57/00 , B65B65/02 , B65B3/00 , B65B51/22
CPC分类号： B65B7/161 , B65B3/003 , B65B7/00 , B65B37/06 , B65B43/54 , B65B51/22 , B65B55/04 , B65B55/08 , B65B57/00 , B65B65/02
摘要： Apparatus for filling devices that are penetrable for filling the devices with a substance, and resealable for sealing the resulting hole. A device support supports at least one such device in a substantially fixed position relative to the support during filling and/or resealing. A manifold drivingly mounted over the device support can include (1) a cartridge including a filling needle for penetrating a resealable stopper and introducing a substance therethrough into the device, a mount for mounting the cartridge on the manifold, and a removable cover releasably coupled to the mount for covering the filling needle during transportation, installation and/or removal of the cartridge from the manifold. The manifold can include a thermal source for heating a penetrated region of the stopper and, sealing the hole.
摘要翻译：用于填充用于将材料填充到装置中的可渗透装置的装置，并且可重新密封用于密封所产生的孔。装置支撑件在填充和/或再密封期间相对于支撑件支撑至少一个这样的装置，其基本上固定的位置。驱动地安装在装置支撑件上的歧管可以包括（1）包括用于穿透可重新密封的止动件并将物质引入其中的填充针的药筒，用于将药筒安装在歧管上的支架和可释放地联接到用于在从歧管运输，安装和/或移除药筒期间覆盖填充针的安装件。歧管可以包括用于加热塞子的穿透区域并密封孔的热源。

2. 发明申请

US20150108174A1 Dispenser with Variable-Volume Storage Chamber, One-Way Valve, and Manually-Depressible Actuator 审中-公开
标题翻译：具有可变容积存储室，单向阀和手动可压缩致动器的分配器
公开(公告)号：US20150108174A1
公开(公告)日：2015-04-23
申请号：US14584678
申请日：2014-12-29
申请人： MedInstill Development LLC
发明人： Daniel Py
IPC分类号： G01F11/02 , B65D83/00
CPC分类号： G01F11/021 , B05B11/3001 , B05B11/3015 , B05B11/3032 , B05B11/3047 , B05B11/3074 , B65D47/2031 , B65D83/00 , B65D83/0033 , B65D83/0072 , G01F11/02
摘要： A dispenser has a housing, and a variable-volume storage chamber formed within the housing and defining a substantially fluid-tight seal between the chamber and exterior of the housing for storing a substance to be dispensed. A piston is mounted within the housing, and a one-way valve is mounted within the housing and coupled in fluid communication with the variable-volume storage chamber. A compression chamber is coupled in fluid communication between the piston and one-way valve, and at least one of the piston and valve is manually depressible relative to the other between (i) a first position in which the piston is located at least partially outside of the compression chamber for permitting substance to flow from the variable-volume storage chamber into the compression chamber, and (ii) a second position in which the piston is located at least partially within the compression chamber for pressurizing substance within the compression chamber above a valve opening pressure and, in turn, dispensing substance through the one-way valve and out of the dispenser.
摘要翻译：分配器具有壳体和形成在壳体内的可变容积的储存室，并且在壳体的室和外部之间限定基本上流体密封的密封，用于存储待分配的物质。活塞安装在壳体内，并且单向阀安装在壳体内并且与可变容积存储室流体连通地联接。压缩室在活塞和单向阀之间流体连通地联接，并且活塞和阀门中的至少一个在第一位置之间相对于另一个手动地相对地被压下，其中活塞位于至少部分外部的压缩室，用于允许物质从可变容积的储存室流入压缩室，以及（ii）第二位置，其中活塞至少部分地位于压缩室内，用于将压缩室内的物质加压在压缩室的上方打开阀门的压力，并通过单向阀分配物质并从分配器中分出物质。

3. 发明授权

US10464801B2 One-way valve and apparatus and method of using the valve 有权
公开(公告)号：US10464801B2
公开(公告)日：2019-11-05
申请号：US15949501
申请日：2018-04-10
申请人： MedInstill Development LLC
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B67D1/00 , B67D1/10 , B67D1/12 , B67D1/08 , B67D3/00 , B67D3/04 , B65B39/00 , B65D51/00 , B05B11/00 , B65D51/16 , F04B53/10
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

4. 发明授权

US10086963B2 Sterilizing apparatus and related method 有权
公开(公告)号：US10086963B2
公开(公告)日：2018-10-02
申请号：US14704549
申请日：2015-05-05
申请人： MedInstill Development LLC
发明人： Daniel Py , Norbert Assion , Nathaniel Houle , Debashis Sahoo , M. Jeffrey Willey , Eric E. Hartman , John Guthy
IPC分类号： B65B55/10 , B65D51/00 , B65D51/18 , B65B51/22 , B65B55/02 , B65B3/00 , B65B7/28
摘要： A sterilizing apparatus and related method are provided for sterilizing an object, such as a container. The sterilizing apparatus may include a housing, a source of fluid sterilant, a fluid sterilant station for transmitting fluid sterilant onto a surface of the object, a flow system for circulating air or gas within the housing, a system for removing fluid sterilant from the surface of the object, and a system for evacuating fluid sterilant from the housing. The container may include a body defining a storage chamber for receiving a product, and a container closure. A sealing portion may be engageable with the body to form a substantially dry hermetic seal between the container closure and body.

5. 发明授权

US09783326B2 Adjustable filling and sealing method and apparatus therefor 有权
公开(公告)号：US09783326B2
公开(公告)日：2017-10-10
申请号：US14294403
申请日：2014-06-03
申请人： MedInstill Development LLC
发明人： Daniel Py , Benoit Adamo , John Guthy
IPC分类号： B65B3/00 , A61L2/10 , A61M5/178 , B29C65/00 , B65B43/00 , B65B51/00
CPC分类号： B65B3/006 , A61L2/10 , A61M5/1782 , B29C66/80 , B65B3/003 , B65B43/00 , B65B51/00 , Y10T29/49716
摘要： An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one filling or needle assembly and is adjustable to receive a plurality of filling or needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of containers or vials that are to be filled concurrently and adjusting an assembly to include at least one filling or needle assembly and at least one seal assembly. A number of the filling or needle assemblies and the seal assemblies equals the number of containers or vials.

6. 发明授权

US09377338B2 Dispenser with variable-volume storage chamber, one-way valve, and manually-depressible actuator 有权
公开(公告)号：US09377338B2
公开(公告)日：2016-06-28
申请号：US14584678
申请日：2014-12-29
申请人： MedInstill Development LLC
发明人： Daniel Py
IPC分类号： B65D88/54 , G01F11/02 , B05B11/00 , B65D83/00 , B65D47/20
CPC分类号： G01F11/021 , B05B11/3001 , B05B11/3015 , B05B11/3032 , B05B11/3047 , B05B11/3074 , B65D47/2031 , B65D83/00 , B65D83/0033 , B65D83/0072 , G01F11/02
摘要： A dispenser has a housing, and a variable-volume storage chamber formed within the housing and defining a substantially fluid-tight seal between the chamber and exterior of the housing for storing a substance to be dispensed. A piston is mounted within the housing, and a one-way valve is mounted within the housing and coupled in fluid communication with the variable-volume storage chamber. A compression chamber is coupled in fluid communication between the piston and one-way valve, and at least one of the piston and valve is manually depressible relative to the other between (i) a first position in which the piston is located at least partially outside of the compression chamber for permitting substance to flow from the variable-volume storage chamber into the compression chamber, and (ii) a second position in which the piston is located at least partially within the compression chamber for pressurizing substance within the compression chamber above a valve opening pressure and, in turn, dispensing substance through the one-way valve and out of the dispenser.

7. 发明授权

US09241874B2 Apparatus and method for filling containers 有权
标题翻译：容器灌装装置及方法
公开(公告)号：US09241874B2
公开(公告)日：2016-01-26
申请号：US13770510
申请日：2013-02-19
申请人： MedInstill Development LLC
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
IPC分类号： A61J1/14 , A61J11/00 , B65D51/00 , A61J9/00
CPC分类号： A61J11/0005 , A61J1/1406 , A61J9/003 , A61J11/04 , B65D51/002
摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.
摘要翻译：提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

8. 发明申请

US20180354775A1 ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE 审中-公开
公开(公告)号：US20180354775A1
公开(公告)日：2018-12-13
申请号：US15949501
申请日：2018-04-10
申请人： MedInstill Development LLC
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B67D1/10 , F04B53/10 , B67D1/00 , B65B39/00 , B65D51/00 , B67D3/04 , B67D1/12 , B65D51/16 , B05B11/00 , B67D3/00 , B67D1/08
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

9. 发明申请

US20170341848A1 DISPENSER WITH ONE-WAY VALVE FOR STORING AND DISPENSING SUBSTANCES 审中-公开
公开(公告)号：US20170341848A1
公开(公告)日：2017-11-30
申请号：US15621818
申请日：2017-06-13
申请人： MedInstill Development LLC
发明人： Daniel Py , Julian Chan , David Fellows , Eric E Hartman , Bing He
IPC分类号： B65D83/00 , G01F11/02 , A61M35/00 , B05B11/00 , A45D34/04 , G01F11/08 , B65B1/04
CPC分类号： B65D83/0094 , A45D34/04 , A45D2200/055 , A45D2200/056 , A61M35/003 , B05B11/00416 , B05B11/3015 , B05B11/3032 , B05B11/3033 , B05B11/3094 , B65B1/04 , B65D83/0033 , G01F11/025 , G01F11/08
摘要： A dispenser has a body with a storage chamber for storing product. A one-way valve of the dispenser includes a valve seat and flexible valve cover seated on the valve seat and defining a normally-closed seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat to allow the passage of substance through the seam and out of the dispenser.

10. 发明申请

US20170334585A1 SEALED CONTAINERS AND METHODS OF FILLING AND RESEALING SAME 审中-公开
公开(公告)号：US20170334585A1
公开(公告)日：2017-11-23
申请号：US15584954
申请日：2017-05-02
申请人： MedInstill Development LLC
发明人： Daniel Py , Norbert M. Assion
IPC分类号： B65B3/00 , A61J1/18 , A61J1/14 , B65B7/16 , B65B51/10 , B65B55/08 , B65D51/00 , B65B3/02 , B65B39/00 , A61J1/20
CPC分类号： B65B3/003 , A61J1/1406 , A61J1/1412 , A61J1/1425 , A61J1/1431 , A61J1/1468 , A61J1/18 , A61J1/201 , A61J1/2013 , A61J1/2055 , A61J1/2075 , A61J1/2096 , A61M2207/00 , A61M2209/045 , B65B3/027 , B65B7/161 , B65B51/10 , B65B55/08 , B65B2039/009 , B65D51/002
摘要： A container and method for filling same. The container includes a penetrable and resealable portion that is resealable, and a container body having a sealed empty chamber in fluid communication with the penetrable and resealable portion for receiving therein a substance. The resealable member may be dome-shaped or have a convex outer surface. A method of filling the container includes penetrating the penetrable and resealable portion with an injection member and introducing a substance into the chamber, withdrawing the injection member, and resealing the penetration hole in the resealable member made by the injection member during penetration.

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