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1. 发明授权

US08030315B2 DPP-IV inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating diabetes or obesity 有权
标题翻译： DPP-IV抑制剂包括β-氨基，其制备方法和含有其的药物组合物用于预防和治疗糖尿病或肥胖症
公开(公告)号：US08030315B2
公开(公告)日：2011-10-04
申请号：US12596281
申请日：2008-04-18
申请人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myun Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
发明人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myun Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
IPC分类号： A61K31/4965 , C07D241/04
CPC分类号： C07D241/08
摘要： The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
摘要翻译：本发明提供了含有β-氨基的新型杂环化合物，其制备方法以及含有相同杂环化合物或其药学上可接受的盐作为有效成分的药物组合物。本发明的杂环化合物显示优异的DPP-IV抑制活性和生物利用度，因此可用于预防或治疗DPP-IV相关疾病如糖尿病或肥胖症。

2. 外观设计

USD413309S Hand-held computer 失效
公开(公告)号：USD413309S
公开(公告)日：1999-08-31
申请号：US87032
申请日：1998-04-24
申请人： Kyung Jin Park
设计人： Kyung Jin Park

3. 发明申请

US20120208092A1 AMORPHOUS ANODE ACTIVE MATERIAL, PREPARATION METHOD OF ELECTRODE USING THE SAME, SECONDARY BATTERY CONTAINING THE SAME, AND HYBRID CAPACITOR 审中-公开
标题翻译：非阳极阳极活性材料，使用该阳极的电极的制备方法，包含该阳极的二次电池和混合电容器
公开(公告)号：US20120208092A1
公开(公告)日：2012-08-16
申请号：US13390099
申请日：2010-08-12
申请人： Jun-Hwan Ku , Kyung-Jin Park , Ji-Sun Kim , Ji-Heon Ryu , Seung-Mo Oh
发明人： Jun-Hwan Ku , Kyung-Jin Park , Ji-Sun Kim , Ji-Heon Ryu , Seung-Mo Oh
IPC分类号： H01M4/48 , H01M4/485 , H01M4/525 , H01G9/04 , H01M10/056 , H01M4/04 , B05D5/12 , H01M4/58 , H01M4/505
CPC分类号： H01M4/485 , H01G11/04 , H01G11/38 , H01G11/46 , H01G11/50 , H01M2/16 , H01M4/131 , H01M4/1391 , H01M4/505 , H01M4/525 , H01M4/5825 , H01M4/622 , H01M4/623 , H01M4/625 , H01M4/661 , H01M10/052 , H01M10/0568 , H01M10/0569 , H01M2004/027 , Y02E60/13 , Y10T428/2982
摘要： An amorphous anode active material, a preparation method of an electrode using the same, a secondary battery containing the same, and a hybrid capacitor are provided. The amorphous anode active material includes at least one of a metal oxide or a metal phosphate, and the metal oxide or the metal phosphate is amorphous. The metal oxide has the form of MOx (0
摘要翻译：提供非晶阳极活性物质，使用其的电极的制备方法，含有它的二次电池和混合电容器。无定形阳极活性材料包括金属氧化物或金属磷酸盐中的至少一种，并且金属氧化物或金属磷酸盐是无定形的。金属氧化物具有MOx（0

4. 发明申请

US20070242793A1 Spacer grid spring for increasing the conformal contact area with fuel rod 有权
标题翻译：间隔栅格弹簧用于增加与燃料棒的共形接触面积
公开(公告)号：US20070242793A1
公开(公告)日：2007-10-18
申请号：US11707450
申请日：2007-02-16
申请人： Kee-Nam Song , Kyung-Ho Yoon , Kun-Woo Song , Kang-Hee Lee , Kyung-Jin Park
发明人： Kee-Nam Song , Kyung-Ho Yoon , Kun-Woo Song , Kang-Hee Lee , Kyung-Jin Park
IPC分类号： G21C3/34
CPC分类号： G21C3/356 , G21Y2002/201 , G21Y2002/206 , G21Y2002/303 , G21Y2004/30 , Y02E30/40
摘要： A grid strap includes a spacer grid spring that increases the conformal contact area with a fuel rod of a nuclear fuel rod assembly. The shape of the spacer grid spring of the grid strap which is in contact with the fuel rod is optimized, thereby the elasticity of the spacer grid spring contacting the fuel rod is increased, the conformal contact area with a contact portion of the spacer grid spring contacting the fuel rod when the fuel rod is inserted into each cell of a spacer grid is expanded to obtain uniform stress distribution, and excessive plastic deformation of the spacer grid spring can be reduced. Further, magnitude and distribution of contact pressure between the fuel rod and the spacer grid spring are improved, thereby reducing the possibility of fretting wear caused by contact between the fuel rod and the spacer grid spring. The elastic behavior region of the spacer grid spring is expanded, so that the fuel rod can be reliably supported until the lifetime of the fuel rod expires despite changes in the supporting conditions of the fuel rod.
摘要翻译：格栅带包括间隔栅格弹簧，其增加与核燃料棒组件的燃料棒的共形接触面积。与燃料棒接触的网格带的间隔栅格弹簧的形状被优化，从而与接触燃料棒的间隔栅格弹簧的弹性增加，与间隔栅格弹簧的接触部分的共形接触面积当将燃料棒插入到间隔栅格的每个电池中时，使燃料棒接触而膨胀以获得均匀的应力分布，并且可以减小间隔栅格弹簧的过大的塑性变形。此外，燃料棒和间隔栅格弹簧之间的接触压力的大小和分布得到改善，从而降低了由于燃料棒和间隔栅格弹簧之间的接触引起的微动磨损的可能性。间隔栅格弹簧的弹性行为区域被扩大，使得燃料棒可以被可靠地支撑，直到燃料棒的寿命尽管燃料棒的支撑条件发生变化而过期。

5. 发明申请

US20120209673A1 System and Method for Merchant's Benefit-focused Electronic Coupon Distribution Business 审中-公开
标题翻译：以商业利益为重点的电子优惠券分销业务的制度与方法
公开(公告)号：US20120209673A1
公开(公告)日：2012-08-16
申请号：US13368042
申请日：2012-02-07
申请人： Kyung Jin Park
发明人： Kyung Jin Park
IPC分类号： G06Q30/02
CPC分类号： G06Q30/02
摘要： The present invention relates to a system and method for merchant's benefit-focused electronic coupon distribution business. The invention provides an online platform connecting merchants to targeted consumers without sales people. The online platform provides merchants with profile pages where the merchants can manage and sell coupon offerings. Consumers can search and purchase one-time use coupons based on the coupon offerings. Each one-time use coupon carries unique identification number and code, and the coupon is tracked to provide information back to registered merchants. This invention minimizes the risk and marketing promotion cost by shifting the burden of marketing cost to the consumers' side. Instead of paving for marketing costs upfront, merchants receive micropayments from consumers through coupon offerings and selling one-time use coupons. This invention creates a get-paid-to-participate-marketing for merchants, and ways to access more discounts from more local businesses for consumers.
摘要翻译：本发明涉及一种以商人利益为重点的电子票券分销业务的系统和方法。本发明提供了一种在线平台，可将商家连接到没有销售人员的目标消费者。在线平台为商家提供了商家可以管理和出售优惠券产品的个人资料页面。消费者可以根据优惠券搜索和购买一次性使用优惠券。每一次使用优惠券都带有唯一的识别号码和代码，并且跟踪优惠券以向注册商家提供信息。本发明通过将营销成本的负担转移到消费者方面来最小化风险和营销推广成本。商家预先购买营销费用，而不是通过优惠券和销售一次性使用优惠券，从消费者那里获得小额支付。本发明为商家创造了有偿参与的营销渠道，以及为更多本地企业为消费者提供更多折扣的途径。

6. 发明授权

US08097704B2 Antibody specifically binding to DR5 and composition for preventing or treating cancers comprising the same 有权
标题翻译：与DR5特异性结合的抗体和用于预防或治疗包含其的癌症的组合物
公开(公告)号：US08097704B2
公开(公告)日：2012-01-17
申请号：US12307293
申请日：2007-05-31
申请人： Yong Sung Kim , Myung Hee Kwon , Seung Hyun Lee , Kyung Jin Park , Hae Won Lee
发明人： Yong Sung Kim , Myung Hee Kwon , Seung Hyun Lee , Kyung Jin Park , Hae Won Lee
IPC分类号： C07K16/00
CPC分类号： C07K16/2878 , A61K2039/505 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/92
摘要： The present invention provides an antibody specifically binding to death receptor 5 (DR5), which is selected from the group consisting of: an antibody comprising a heavy chain variable region (VH) having the amino acid sequences of SEQ ID NOs: 1 to 3 at complementary determining regions (CDRs) and a light chain variable region (VL) having the amino acid sequences of SEQ ID NOs: 4 to 6 at CDRs; and an antibody comprising a (VH) having the amino acid sequences of SEQ ID NOs: 7 to 9 at CDRs and a (VL) having the amino acid sequences of SEQ ID NOs: 10 to 12 at CDRs, and a composition for preventing or treating a cancer comprising the same. The antibody of the present invention can be effectively used for the prevention or treatment of various cancers, through inducing autophagic cell death of TRAIL-sensitive cancer cells as well as TRAIL-resistant cancer cells by specific binding to DR5.
摘要翻译：本发明提供了特异性结合死亡受体5（DR5）的抗体，其选自：包含具有SEQ ID NO：1至3的氨基酸序列的重链可变区（VH）的抗体，互补决定区（CDR）和在CDR中具有SEQ ID NO：4至6的氨基酸序列的轻链可变区（VL）; 以及抗体，其包含CDR上具有SEQ ID NO：7至9的氨基酸序列的氨基酸序列的抗体和在CDR中具有SEQ ID NO：10至12的氨基酸序列的（VL），以及用于预防或治疗包含该癌症的癌症。通过特异性结合DR5，本发明的抗体可以通过诱导TRAIL敏感性癌细胞的自噬细胞死亡以及抗TRAIL抗性癌细胞，有效地用于预防或治疗各种癌症。

7. 发明授权

US08085895B2 Spacer grid spring for increasing the conformal contact area with fuel rod 有权
标题翻译：间隔栅格弹簧用于增加与燃料棒的共形接触面积
公开(公告)号：US08085895B2
公开(公告)日：2011-12-27
申请号：US11707450
申请日：2007-02-16
申请人： Kee-Nam Song , Kyung-Ho Yoon , Kun-Woo Song , Kang-Hee Lee , Kyung-Jin Park
发明人： Kee-Nam Song , Kyung-Ho Yoon , Kun-Woo Song , Kang-Hee Lee , Kyung-Jin Park
IPC分类号： G21C3/34
CPC分类号： G21C3/356 , G21Y2002/201 , G21Y2002/206 , G21Y2002/303 , G21Y2004/30 , Y02E30/40
摘要： A grid strap includes a spacer grid spring that increases the conformal contact area with a fuel rod of a nuclear fuel rod assembly. The shape of the spacer grid spring is optimized, thereby increasing the elasticity of the spacer grid spring contacting the fuel rod, expanding the conformal contact area with a contact portion between the spacer grid spring and fuel rod to obtain uniform stress distribution, and reducing excessive plastic deformation of the spacer grid spring. Further, magnitude and distribution of contact pressure between the fuel rod and the spacer grid spring are improved, thereby reducing the possibility of fretting wear caused by contact between the fuel rod and the spacer grid spring. Lastly, the elastic behavior region of the spacer grid spring is expanded, so that the fuel rod can be reliably supported until the fuel rod expires despite changes in the supporting conditions of the fuel rod.
摘要翻译：格栅带包括间隔栅格弹簧，其增加与核燃料棒组件的燃料棒的共形接触面积。间隔栅格弹簧的形状被优化，从而增加与燃料棒接触的间隔栅格弹簧的弹性，将间隔栅格弹簧和燃料棒之间的接触部分扩大共形接触面积，以获得均匀的应力分布，并减少过量间隔网格弹簧的塑性变形。此外，燃料棒和间隔栅格弹簧之间的接触压力的大小和分布得到改善，从而降低了由于燃料棒和间隔栅格弹簧之间的接触引起的微动磨损的可能性。最后，间隔栅格弹簧的弹性行为区域被扩大，使得燃料棒可以被可靠地支撑，直到燃料棒在燃料棒的支撑条件发生变化时才过期。

8. 发明申请

US20090317396A1 ANTIBODY SPECIFICALLY BINDING TO DR5 AND COMPOSITION FOR PREVENTING OR TREATING CANCERS COMPRISING THE SAME 有权
标题翻译：抗体特异性结合DR5及其组合物，用于预防或治疗包括其的癌症
公开(公告)号：US20090317396A1
公开(公告)日：2009-12-24
申请号：US12307293
申请日：2007-05-31
申请人： Yong Sung Kim , Myung Hee Kwon , Seung Hyun Lee , Kyung Jin Park , Hae Won Lee
发明人： Yong Sung Kim , Myung Hee Kwon , Seung Hyun Lee , Kyung Jin Park , Hae Won Lee
IPC分类号： A61K39/395 , C07K16/28 , C12N9/96 , C12N15/11 , C12N1/21
CPC分类号： C07K16/2878 , A61K2039/505 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/92
摘要： The present invention provides an antibody specifically binding to death receptor 5 (DR5), which is selected from the group consisting of: an antibody comprising a heavy chain variable region (VH) having the amino acid sequences of SEQ ID NOs: 1 to 3 at complementary determining regions (CDRs) and a light chain variable region (VL) having the amino acid sequences of SEQ ID NOs: 4 to 6 at CDRs; and an antibody comprising a (VH) having the amino acid sequences of SEQ ID NOs: 7 to 9 at CDRs and a (VL) having the amino acid sequences of SEQ ID NOs: 10 to 12 at CDRs, and a composition for preventing or treating a cancer comprising the same. The antibody of the present invention can be effectively used for the prevention or treatment of various cancers, through inducing autophagic cell death of TRAIL-sensitive cancer cells as well as TRAIL-resistant cancer cells by specific binding to DR5.
摘要翻译：本发明提供了特异性结合死亡受体5（DR5）的抗体，其选自：包含具有SEQ ID NO：1至3的氨基酸序列的重链可变区（VH）的抗体，互补决定区（CDR）和在CDR中具有SEQ ID NO：4至6的氨基酸序列的轻链可变区（VL）; 以及抗体，其包含CDR上具有SEQ ID NO：7至9的氨基酸序列的氨基酸序列的抗体和在CDR中具有SEQ ID NO：10至12的氨基酸序列的（VL），以及用于预防或治疗包含该癌症的癌症。通过特异性结合DR5，本发明的抗体可以通过诱导TRAIL敏感性癌细胞的自噬细胞死亡以及抗TRAIL抗性癌细胞，有效地用于预防或治疗各种癌症。

9. 发明申请

US20100120790A1 DPP-IV INHIBITOR INCLUDING BETA-AMINO GROUP, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTING AND TREATING DIABETES OR OBESITY 有权
标题翻译： DPP-IV抑制剂，其包括氨基甲酰胺组，其制备方法和含有该组合物的预防和治疗糖尿病或肥胖的药物组合物
公开(公告)号：US20100120790A1
公开(公告)日：2010-05-13
申请号：US12596281
申请日：2008-04-18
申请人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myung Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
发明人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myung Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
IPC分类号： A61K31/495 , C07D241/04 , A61P3/10 , A61P3/04
CPC分类号： C07D241/08
摘要： The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
摘要翻译：本发明提供了含有β-氨基的新型杂环化合物，其制备方法以及含有相同杂环化合物或其药学上可接受的盐作为有效成分的药物组合物。本发明的杂环化合物显示优异的DPP-IV抑制活性和生物利用度，因此可用于预防或治疗DPP-IV相关疾病如糖尿病或肥胖症。

10. 发明授权

US06827756B2 Tungsten heavy alloy for penetrating splinter shell and forming method thereof 有权
标题翻译：钨重合金，用于穿透裂片壳及其成型方法
公开(公告)号：US06827756B2
公开(公告)日：2004-12-07
申请号：US10345968
申请日：2003-01-17
申请人： Kyung Jin Park , Joo Ha Ryu
发明人： Kyung Jin Park , Joo Ha Ryu
IPC分类号： C22C104
CPC分类号： F42B12/74 , B22F2998/10 , C22C1/045 , C22C27/04 , B22F3/04 , B22F3/10
摘要： Disclosed are a tungsten material for a penetrating splinter shell and forming method thereof enabling a penetrator to perforate a hard target on high-speed impact as well as having the following splinter cause a severe damage on an inner component by changing a breakage characteristic of the material into brittle fracture from ductile fracture in a manner that a mechanical characteristic of the material is adjusted by controlling a sintering condition and a composition ratio of a tungsten heavy alloy material having Mo added thereto. The present invention includes the steps of mixing 90˜95 wt % W powder, 3.0˜8.0 wt % Mo powder, 0.5˜3.0 wt % Ni powder, and 1.0˜4.0 wt % Fe powder with each other, molding the mixed powders, and sintering the molded powders.
摘要翻译：公开了一种用于穿透碎片壳的钨材料及其形成方法，其能够使穿透器在高速冲击下穿透硬质靶材，并且具有以下碎片，通过改变材料的断裂特性对内部部件造成严重损坏通过控制烧结条件和添加有Mo的钨重质合金材料的组成比来调节材料的机械特性，从而延性断裂成脆性断裂。本发明包括以下步骤：将90〜95重量％的W粉末，3.0〜8.0重量％的Mo粉末，0.5〜3.0重量％的Ni粉末和1.0〜4.0重量％的Fe粉末相互混合，成型混合粉末，烧结成型粉末。

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