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1. 发明申请

WO2008086809A1 A MICROFLUIDIC DEVICE AND A KIT FOR PERFORMING A TEST 审中-公开
标题翻译：微型设备和用于执行测试的工具包
公开(公告)号：WO2008086809A1
公开(公告)日：2008-07-24
申请号：PCT/DK2008/050002
申请日：2008-01-04
申请人： SCANDINAVIAN MICRO BIODEVICES ApS , KRING, Ole , JONSMANN, Jacques , BAU-MADSEN, Niels Kristian
发明人： KRING, Ole , JONSMANN, Jacques , BAU-MADSEN, Niels Kristian
IPC分类号： B01L3/00 , G01N33/543
CPC分类号： B01L3/502746 , B01L2300/0636 , B01L2300/0825 , B01L2300/089 , B01L2300/165 , B01L2400/0406 , B01L2400/0688 , B01L2400/088
摘要： The invention relates to a microfluidic device comprising a flow path with a first and a second opposite solid flow path surfaces (1) and a liquid inlet for said flow path. In the microfluid device at least one solid side wall free section (2) of the flow path (1) is provided by the first and the second opposite solid flow path surfaces in at least said one solid side wall free section (2) and a pair of borderlines (3, 31) defines the edges of the side wall free section (2) of said flow path (1). The pair of borderlines is placed on the first surface of a first and a second opposite surfaces to define the flow path surfaces of said first and second opposite surfaces. The pair of borderlines (3, 31) is defined by an abrupt change of the first and/or the second surface, e.g. in the form of an abrupt change of surface tension and/or an abrupt change of distance between the first and second surfaces beyond and adjacent to the borderlines (3, 31). For example the borderlines (3, 31) may be arranged with a sharp edge with an angle between a flow path surface in the side wall free flow path section and the respective surfaces beyond and, adjacent to the borderlines which is less than 135 degrees, such as about 90 degrees. The flow path comprises an immobilized capture reagent (7) downstream from or in said solid side wall free flow path section (2), said immobilized capture reagent (7) preferably being immobilized onto at least one of said first and second opposite solid flow path surfaces.
摘要翻译：本发明涉及一种微流体装置，其包括具有第一和第二相对的固体流动路径表面（1）的流动路径和用于所述流动路径的液体入口。在微流体装置中，流路（1）的至少一个固体侧壁自由部分（2）由至少所述一个实心侧壁自由部分（2）中的第一和第二相对的固体流动通道表面提供，并且一对边界线（3,31）限定了所述流动路径（1）的侧壁自由部分（2）的边缘。一对边界线放置在第一和第二相对表面的第一表面上，以限定所述第一和第二相对表面的流动路径表面。一对边界线（3,31）由第一和/或第二表面的突然变化限定，例如，其形式是表面张力的突然变化和/或第一和第二表面之间的距离和边界线（3,31）之间的距离的突然变化。例如，边界线（3,31）可以布置成具有在侧壁自由流动路径部分中的流动路径表面与超过小于135度的边界线的相邻表面之间的角度的尖锐边缘，如约90度。流动路径包括在所述固体侧壁自由流动路段部分（2）中或所述固体侧壁自由流动路段部分（2）下游的固定的捕获试剂（7），所述固定化捕获试剂（7）优选固定在所述第一和第二相对固体流动路径中的至少一个表面。

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