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1. 发明专利

JPS63151306A DEVICE AND METHOD FOR MASS TRANSFER INCLUDING BIOLOGICAL AND/OR PHARMACOLOGICAL MEDIUM 失效
公开(公告)号：JPS63151306A
公开(公告)日：1988-06-23
申请号：JP29221287
申请日：1987-11-20
申请人： KOPF HENRY B
发明人： KOPF HENRY B
IPC分类号： B01D63/02 , B01D61/32 , B01D63/08 , B01D65/08 , C12M1/12 , C12M3/06 , C12N5/02

2. 发明公开

EP0980285A1 FILTRATION CASSETTE ARTICLE AND FILTER COMPRISING SAME 失效
标题翻译：与此处包含的过滤盒过滤器
公开(公告)号：EP0980285A1
公开(公告)日：2000-02-23
申请号：EP98902780.0
申请日：1998-01-12
申请人： Kopf, Henry B.
发明人： Kopf, Henry B.
IPC分类号： B01D25/12 , B01D61/00 , B01D71/06
CPC分类号： B01D63/084 , B01D63/081
摘要： A filtration cassette (12) of a type comprising filter sheets arranged in a multilaminate peripherally bonded array, wherein the filter sheets (104) alternate with permeate (106) and retentate (102) sheets. A stacked assembly (200) of such filtration cassettes may be employed to form stacked cassette filter. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.

3. 发明公开

EP0814896A4 FILTRATION CASSETTE ARTICLE, AND FILTER COMPRISING SAME 失效
标题翻译： FILTER MIT DARIN ENTHALTENER FILTRATIONSKASSETTE
公开(公告)号：EP0814896A4
公开(公告)日：1998-09-09
申请号：EP96910322
申请日：1996-02-22
申请人： KOPF HENRY B
发明人： KOPF HENRY B
IPC分类号： B01D25/12 , B01D63/08 , C12M3/06 , B01D63/00 , B01D25/00
CPC分类号： C12M47/02 , B01D63/084
摘要： A filtration cassette (12), of a type comprising membrane filter sheets (104, 108) arranged in a peripherally bonded array of multilaminate character wherein the filter sheets alternate with foraminous (e.g., screen or mesh) sheet members (106), ribbed retentate sheet members (102), and a cross-flow filter (10) comprising a multiplicity of stacked filtration cassettes of such type. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.
摘要翻译：一种过滤盒（12），其类型包括以多层特性的外围结合阵列布置的膜过滤片（104,108），其中过滤片与多孔（例如筛或网）片构件（106）交替，肋状渗余物薄片构件（102）和包括多个这种类型的堆叠过滤盒的错流过滤器（10）。本发明的过滤盒和过滤器可以有利地用于水性生物质悬浮液的脱水，蛋白质的脱盐，从细胞悬液中去除分泌的代谢物等。

4. 发明公开

EP0310385A2 Filter plate, filter plate element, and filter comprising same 失效
标题翻译：滤波器，滤波器和滤波器。
公开(公告)号：EP0310385A2
公开(公告)日：1989-04-05
申请号：EP88309035.9
申请日：1988-09-29
申请人： Kopf, Henry B.
发明人： Kopf, Henry B.
IPC分类号： B01D29/00 , B01D61/00 , B01D71/00
CPC分类号： B01D63/082 , B01D25/215
摘要： A filter plate (210) which is longutidinally partitioned between its inlet (220) and outlet (224) ends, and features liquid feed and collection troughs at the respective ends which are of progressively decreasing depth from the medial part of the trough to the extremities thereof. Such plates (210) may be associated in opposed, relatively inverted pairs to form enclosed flow channels characterized by fluid flow rates which are substantially uniform across the full transverse extent of the flow path and which facilitate the utilization of the full areal extent of the filter media employed therewith. Also described in a unitary filter element which may be usefully employed in the filter.
The filter of the invention may be highly efficiently employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.
摘要翻译：在其入口（220）和出口（224）之间长切口分隔的过滤板（210）终止，并且在相应端部处具有从槽的内侧部分到末端逐渐减小的深度的液体进料和收集槽它们。这种板（210）可以以相对的相对倒置的对相关联，以形成封闭的流动通道，其特征在于在流动通道的整个横向范围内基本均匀的流体流速，并且有助于利用过滤器的全面积范围使用媒体。也可以用于过滤器中有用的单一过滤器元件中描述。本发明的过滤器可以被高效地用于脱水水生物质悬浮液，脱盐蛋白质，从细胞悬浮液中除去分泌的代谢物等。

5. 发明公开

EP0269444A2 Apparatus and method for mass transfer involving biological/pharmaceutical media 失效
标题翻译： Vorrichtung und Verfahren zum Massentransfer von biologisch-pharmazeutischen Medien。
公开(公告)号：EP0269444A2
公开(公告)日：1988-06-01
申请号：EP87310442.6
申请日：1987-11-26
申请人： Kopf, Henry B.
发明人： Kopf, Henry B.
IPC分类号： C12M1/12 , B01D65/08 , B01D61/32
CPC分类号： B01D65/08 , B01D61/32 , B01D63/084 , B01D2321/168 , B01D2321/2066 , B01D2321/2083 , C12M25/10 , C12M29/12 , C12M29/16
摘要： A mass transfer apparatus and method is based upon use of a mass transfer chamber (12), such as a hollow fiber membrane bioreactor, with means to change the directional flow (16) therethrough for enhancement of the mass transfer operation. The invention has particular utility in cell growth systems, where the periodic reversal of flow direction of a nutrient stream passed through the bioreactor equalizes dispersion of cell growth through the bioreactor and enhances the transport of metabolic waste from the cells being grown.
摘要翻译：传质装置和方法基于使用诸如中空纤维膜生物反应器的传质室（12），其具有改变方向流（16）的装置，用于增强传质操作。本发明在细胞生长系统中具有特别的用途，其中通过生物反应器的营养物流的流动方向的周期性反转平衡了通过生物反应器的细胞生长的分散，并增强了来自正在生长的细胞的代谢废物的转运。

6. 发明授权

EP0980285B1 FILTRATION CASSETTE ARTICLE AND FILTER COMPRISING SAME 失效
标题翻译：与此处包含的过滤盒过滤器
公开(公告)号：EP0980285B1
公开(公告)日：2005-01-12
申请号：EP98902780.0
申请日：1998-01-12
申请人： Kopf, Henry B.
发明人： Kopf, Henry B.
IPC分类号： B01D63/08
CPC分类号： B01D63/084 , B01D63/081
摘要： A filtration cassette (12) of a type comprising filter sheets arranged in a multilaminate peripherally bonded array, wherein the filter sheets (104) alternate with permeate (106) and retentate (102) sheets. A stacked assembly (200) of such filtration cassettes may be employed to form stacked cassette filter. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.

7. 发明公开

EP0980285A4 FILTRATION CASSETTE ARTICLE AND FILTER COMPRISING SAME 失效
标题翻译： FILTER MIT DARIN ENTHALTENER FILTRATIONSKASSETTE
公开(公告)号：EP0980285A4
公开(公告)日：2002-04-24
申请号：EP98902780
申请日：1998-01-12
申请人： KOPF HENRY B
发明人： KOPF HENRY B
IPC分类号： B01D25/12 , B01D63/08 , C12M1/12 , C12M3/06
CPC分类号： B01D63/084 , B01D63/081
摘要： A filtration cassette (12) of a type comprising filter sheets arranged in a multilaminate peripherally bonded array, wherein the filter sheets (104) alternate with permeate (106) and retentate (102) sheets. A stacked assembly (200) of such filtration cassettes may be employed to form stacked cassette filter. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.
摘要翻译：一种过滤盒（12），其包括布置成多层周边粘结阵列的过滤片，其中过滤片（104）与渗透物（106）和滞留物片（102）交替。这种过滤盒的堆叠组件（200）可以用于形成堆叠的盒式过滤器。本发明的过滤盒和过滤器可以有利地用于水性生物质悬浮液的脱水，蛋白质的脱盐，从细胞悬液中去除分泌的代谢物等。

8. 发明公开

EP1424906A1 METHOD AND APPARATUS FOR SEPARATION OF MILK, COLOSTRUM, AND WHEY 审中-公开
标题翻译：方法和设备牛奶分离和乳清BEAST MILK
公开(公告)号：EP1424906A1
公开(公告)日：2004-06-09
申请号：EP02798182.8
申请日：2002-09-10
申请人： Kopf, Henry B. , Kopf, III, Henry
发明人： Kopf, Henry B. , Kopf, III, Henry
IPC分类号： A23C19/00
CPC分类号： B01D61/142 , A23C9/1422 , A23C9/1425 , B01D61/022 , B01D61/025 , B01D61/12 , B01D61/145 , B01D61/147 , B01D61/16 , B01D61/22 , B01D2311/04 , B01D2311/10 , B01D2311/165
摘要： Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, colostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, colostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.

9. 发明授权

EP0814896B1 FILTRATION CASSETTE ARTICLE, AND FILTER COMPRISING THE SAME 失效
标题翻译：与此处包含的过滤盒过滤器
公开(公告)号：EP0814896B1
公开(公告)日：2002-09-04
申请号：EP96910322.5
申请日：1996-02-22
申请人： Kopf, Henry B.
发明人： Kopf, Henry B.
IPC分类号： B01D63/00 , B01D25/00 , B01D63/08 , C12M3/06
CPC分类号： C12M47/02 , B01D63/084
摘要： A filtration cassette (12), of a type comprising membrane filter sheets (104, 108) arranged in a peripherally bonded array of multilaminate character wherein the filter sheets alternate with foraminous (e.g., screen or mesh) sheet members (106), ribbed retentate sheet members (102), and a cross-flow filter (10) comprising a multiplicity of stacked filtration cassettes of such type. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.

10. 发明公开

EP0814896A1 FILTRATION CASSETTE ARTICLE, AND FILTER COMPRISING SAME 失效
标题翻译：与此处包含的过滤盒过滤器
公开(公告)号：EP0814896A1
公开(公告)日：1998-01-07
申请号：EP96910322.0
申请日：1996-02-22
申请人： Kopf, Henry B.
发明人： Kopf, Henry B.
IPC分类号： B01D25 , B01D63 , C12M3
CPC分类号： C12M47/02 , B01D63/084
摘要： A filtration cassette (12), of a type comprising membrane filter sheets (104, 108) arranged in a peripherally bonded array of multilaminate character wherein the filter sheets alternate with foraminous (e.g., screen or mesh) sheet members (106), ribbed retentate sheet members (102), and a cross-flow filter (10) comprising a multiplicity of stacked filtration cassettes of such type. The filtration cassettes and filter of the invention may be advantageously employed for dewatering of aqueous biomass suspensions, desalting of proteins, removal of secreted metabolites from cellular suspensions, and the like.

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