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1. 发明授权

US4715959A Apparatus and method for controlling ultrafiltration during hemodialysis 失效
标题翻译：血液透析过程中超滤的设备及方法
公开(公告)号：US4715959A
公开(公告)日：1987-12-29
申请号：US606505
申请日：1984-05-03
申请人： Jonathan M. Allan , Richard J. Burton , Volker Jurock
发明人： Jonathan M. Allan , Richard J. Burton , Volker Jurock
IPC分类号： A61M1/16 , B01D13/00
CPC分类号： A61M1/16 , A61M1/1641 , A61M1/1662 , Y10S210/929
摘要： Hemodialysis ultrafiltration apparatus comprises a dialyzer. A closed circuit is provided for supplying fresh dialysate to and for removing spent dialysate from the dialyzer. Blood is supplied to and removed from the dialyzer. The closed circuit for supplying fresh dialysate and removing spent dialysate is apportioned into below mean dialyzer blood pressure and above atmospheric pressure sections, with the dialyzer being positioned in the below mean dialyzer blood pressure section. A mechanism is provided for controlling the pressure of fresh dialysate introduced into the below mean dialyzer blood pressure section to substantially match the pressure on the dialysate side of the dialyzer. A mechanism is provided for controlling the above atmospheric pressure portion of the spent dialysate circuit. A pump removes spent dialysate of equivalent ultrafiltrate volume from the closed circuit to control the rate of ultrafiltrate removal from blood in the dialyzer, thus affecting the pressure on the dialysate side of the dialyzer required to sustain that rate.A method of hemodialytic ultrafiltration is carried out substantially in accordance with the above-described apparatus.
摘要翻译：血液透析超滤装置包括透析器。提供闭合电路用于向透析器中提供新鲜透析液并从透析器中除去用过的透析液。血液被提供给透析器并从透析器中取出。用于提供新鲜透析液和去除用过的透析液的闭路分配到低于平均透析器血压和高于大气压段，透析器位于下面的平均透析器血压部分中。提供了用于控制引入到下面的平均透析器血压部分中的新鲜透析液的压力以基本上匹配透析器透析液侧的压力的机构。提供了用于控制用过的透析液回路的上述大气压部分的机构。泵从封闭回路中去除等效超滤液体积的透析液，以控制从透析器血液中除去超滤液的速率，从而影响透析器的透析液压力以维持该速率。基本上根据上述装置进行血液透析超滤的方法。

2. 发明授权

US4769134A Open patient fluid management method and system 失效
标题翻译：打开患者流体管理方法和系统
公开(公告)号：US4769134A
公开(公告)日：1988-09-06
申请号：US808828
申请日：1985-12-13
申请人： Jonathan M. Allan , Perry W. Guinn
发明人： Jonathan M. Allan , Perry W. Guinn
IPC分类号： A61M1/16 , B01D13/00
CPC分类号： A61M1/16 , A61M1/1639 , A61M1/1649 , Y10S210/929
摘要： An open, volumetrically regulated patient fluid management system and method are disclosed. Fresh fluid is metered into a patient fluid exchange unit by a first metering device and spent fluid is drawn out by a pump. A back pressure regulator is provided across the pump to maintain its output pressure at a constant value. To the output of the pump are connected a second metering device and an open drain circuit. The second metering device meters out of the patient fluid exchange unit a predetermined quantity of spent fluid. The open drain circuit drains any fluid pumped by the pump, but not removed by the second metering device, to a drain open to atmospheric pressure. When the dialysis unit is deenergized, fluid in the dialyzer returns rapidly to atmospheric pressure by virtue of the open path through the open drain circuit, pump and back pressure regulator to the dialyzer.
摘要翻译：公开了一种开放的，体积调节的患者流体管理系统和方法。新鲜流体通过第一计量装置计量到患者流体交换单元中，废液由泵抽出。在泵之间设置背压调节器，以将其输出压力保持在恒定值。泵的输出端连接有第二计量装置和开漏电路。第二计量装置从患者流体交换单元中取出预定量的废流体。开放漏极电路将由泵泵送的任何流体排放到没有被第二计量装置排出的流体，以排到大气压力下。当透析单元断电时，透析器中的流体通过开放漏极回路，泵和背压调节器到透析器的开放路径迅速返回到大气压力。

3. 发明授权

US4477342A Apparatus and method for controlling ultrafiltration during hemodialysis 失效
标题翻译：血液透析过程中超滤的设备及方法
公开(公告)号：US4477342A
公开(公告)日：1984-10-16
申请号：US413287
申请日：1982-08-31
申请人： Jonathan M. Allan , Richard J. Burton , Volker Jurock
发明人： Jonathan M. Allan , Richard J. Burton , Volker Jurock
IPC分类号： A61M1/14 , A61M1/16 , B01D31/00
CPC分类号： A61M1/16 , A61M1/1641 , A61M1/1662 , Y10S210/929
摘要： Hemodialysis ultrafiltration apparatus comprises a dialyzer. A closed circuit is provided for supplying fresh dialysate to and for removing spent dialysate from the dialyzer. Blood is supplied to and removed from the dialyzer. The closed circuit for supplying fresh dialysate and removing spent dialysate is apportioned into below mean dialyzer blood pressure and above atmospheric pressure sections, with the dialyzer being positioned in the below mean dialyzer blood pressure section. A mechanism is provided for controlling the pressure of fresh dialysate introduced into the below mean dialyzer blood pressure section to substantially match the pressure on the dialysate side of the dialyzer. A mechanism is provided for controlling the above atmospheric pressure portion of the spent dialysate circuit. A pump removes spent dialysate of equivalent ultrafiltrate volume from the closed circuit to control the rate of ultrafiltrate removal from blood in the dialyzer, thus affecting the pressure on the dialysate side of the dialyzer required to sustain that rate.A method of hemodialytic ultrafiltration is carried out substantially in accordance with the above-described apparatus.
摘要翻译：血液透析超滤装置包括透析器。提供闭合电路用于向透析器中提供新鲜透析液并从透析器中除去用过的透析液。血液被提供给透析器并从透析器中取出。用于提供新鲜透析液和去除用过的透析液的闭路分配到低于平均透析器血压和高于大气压段，透析器位于下面的平均透析器血压部分中。提供了用于控制引入到下面的平均透析器血压部分中的新鲜透析液的压力以基本上匹配透析器透析液侧的压力的机构。提供了用于控制用过的透析液回路的上述大气压部分的机构。泵从封闭回路中去除等效超滤液体积的透析液，以控制从透析器血液中除去超滤液的速率，从而影响透析器的透析液压力以维持该速率。基本上根据上述装置进行血液透析超滤的方法。

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