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1. 发明授权

EP0149631B1 FREE LIGAND ASSAY 失效
标题翻译：免费配乐测试
公开(公告)号：EP0149631B1
公开(公告)日：1988-11-23
申请号：EP84902530.9
申请日：1984-06-22
申请人： EKINS, Roger Philip , JACKSON, Thomas Michael
发明人： EKINS, Roger Philip , JACKSON, Thomas Michael
IPC分类号： G01N33/53 , G01N33/78
CPC分类号： G01N33/78 , G01N33/53 , Y10S436/804 , Y10S436/817
摘要： A method of measuring the concentration of a free ligand in a biological fluid containing the free ligand and ligand bound to endogenous binding agent, comprises; a) mixing a sample of the fluid with an analogue of the ligand, a specific binder with which the free ligand and the ligand analogue bind, and an exogenous binding agent which binds the ligand analogue but not the ligand, either the ligand analogue or the specific binder being labelled; b) incubating the resulting mixture so that the ligand and ligand analogue compete for the specific binder; c) determining either the amount of the labelled analogue bound to the specific binder or the exogenous binding agent or the amount of labelled specific binder bound, or not bound, to the ligand analogue; and d) correlating the determined amount to the amount of free ligand present in the sample. The method is especially usefull where the ligand analogue binds with endogenous binding agent and the extent of binding varies from sample to sample of the biological fluid. It may be used to measure concentration of free thyroid hormones and other hormones in body fluids, employing antibodies specific to the ligand analogue as the exogenous binding agents.

2. 发明公开

EP3698753A1 DENTAL FLOSS INSERTION DEVICE 有权
公开(公告)号：EP3698753A1
公开(公告)日：2020-08-26
申请号：EP20155924.2
申请日：2020-02-06
申请人： Jackson, Thomas F.
发明人： Jackson, Thomas F.
IPC分类号： A61C15/04
摘要： A dental floss insertion device for inserting an end of a length of dental floss into an enclosed oral space. The device may include a body and a tip attached to the body and cooperating with the body to define a floss guide path. A first roller may be positioned on a first side of the guide path and a second roller may be positioned on a second side of the guide path. The second roller may be moveable toward and away from the first roller to open and close a nip that receives the length of floss, thereby allowing a user to apply a compressive force on a piece of floss located between the first and second rollers while simultaneously rolling the second roller to advancing the end of the length of floss along the guide path, through the distal orifice, and into an enclosed oral space.

3. 发明公开

EP0149631A1 FREE LIGAND ASSAY 失效
标题翻译：测定游离测试配位体的。
公开(公告)号：EP0149631A1
公开(公告)日：1985-07-31
申请号：EP84902530.0
申请日：1984-06-22
申请人： EKINS, Roger Philip , JACKSON, Thomas Michael
发明人： EKINS, Roger Philip , JACKSON, Thomas Michael
IPC分类号： G01N33 , A61K39
CPC分类号： G01N33/78 , G01N33/53 , Y10S436/804 , Y10S436/817
摘要： Procédé de mesure de la concentration d'un ligand libre dans un fluide biologique contenant le ligand libre et le ligand lié à un agent de liaison endogène, consistant à a) mélanger un échantillon de fluide avec un analogue du ligand, un liant spécifique avec lequel se lient le ligand libre et l'analogue de ligand, et un agent de liaison exogène qui lie l'analogue de ligand mais non pas le ligand, soit l'analogue de ligand soit le liant spécifique étant marqués, b) incuber le mélange résultant de manière à créer une compétition entre le ligand et l'analogue de ligand pour le liant spécifique, c) déterminer soit la quantité de l'analogue marqué lié au liant spécifique ou à l'agent de liaison exogène, soit la quantité de liant spécifique marqué lié, ou non lié, à l'analogue de ligand, et d) établir une corrélation entre la quantité déterminée et la quantité de ligand libre présente dans l'échantillon. Ce procédé est particulièrement utile lorsque l'analogue de ligand se lie avec un agent de liaison endogène et que l'importance de la liaison varie d'un échantillon de fluide biologique à l'autre. Le procédé peut être utilisé pour mesurer la concentration d'hormones thyroïdiennes libres et d'autres hormones dans les fluides du corps, en utilisant des anticorps spécifiques de l'analogue de ligand comme agents de liaison exogènes.

4. 发明专利

CA3013740A1 EXPEDITION CARTS AND ASSOCIATED METHODS 未知
公开(公告)号：CA3013740A1
公开(公告)日：2018-01-22
申请号：CA3013740
申请日：2016-08-05
申请人： JACKSON THOMAS JOSEPH JR
发明人： JACKSON THOMAS JOSEPH
IPC分类号： B62B1/18
摘要： An expedition cart comprising a chassis, configured and dimensioned to support a load, and a first hub and a second hub engaged with the chassis. Each of the first hub and the second hub includes a body with two separate passages at opposing sides of the body. The two separate passages are configured and dimensioned to receive endpoints of respective first and second halves of the chassis.

5. 发明专利

GB0402622D0 Wheel alignment apparatus 未知
公开(公告)号：GB0402622D0
公开(公告)日：2004-03-10
申请号：GB0402622
申请日：2004-02-06
申请人： JACKSON THOMAS

6. 发明专利

DE3475351D1 FREE LIGAND ASSAY 未知
公开(公告)号：DE3475351D1
公开(公告)日：1988-12-29
申请号：DE3475351
申请日：1984-06-22
申请人： EKINS ROGER PHILIP , JACKSON THOMAS MICHAEL
发明人： EKINS ROGER PHILIP
IPC分类号： G01N33/536 , A61K39/00 , G01N33/53 , G01N33/543 , G01N33/78
摘要： PCT No. PCT/GB84/00220 Sec. 371 Date Feb. 20, 1985 Sec. 102(e) Date Feb. 20, 1985 PCT Filed Jun. 22, 1984 PCT Pub. No. WO85/00226 PCT Pub. Date Jan. 17, 1985.A method of measuring the concentration of a free ligand in a biological fluid containing the free ligand and ligand bound to endogenous binding agent, by the steps of (a) mixing a sample of the fluid with an analogue of the ligand, a specific binder with which the free ligand and the ligand analogue bind, and an exogenous binding agent which binds the ligand analogue but not the ligand, either the ligand analogue or the specific binder being labelled, (b) incubating the resulting mixture, (c) determining either the amount of the labelled analogue bound or the amount of labelled specific binder bound, or not bound, to the ligand analogue, and (d) correlating the determined amount to the amount of free ligand present in the sample. The method is useful to measure concentration of free thyroid hormones and other hormones in body fluids, employing antibodies specific to the ligand analogue as the exogenous binding agents.

7. 发明专利

AT38903T 未知
公开(公告)号：AT38903T
公开(公告)日：1988-12-15
申请号：AT84902530
申请日：1984-06-22
申请人： EKINS ROGER PHILIP , JACKSON THOMAS MICHAEL
发明人： EKINS ROGER PHILIP , HOSPITAL MEDICAL SCHOOL DEPART , JACKSON THOMAS MICHAEL , THE MIDDLESEX HOSPITAL MEDICAL
IPC分类号： G01N33/53 , G01N33/78

8. 发明专利

CA236186A ELECTRIC TOASTER 未知
公开(公告)号：CA236186A
公开(公告)日：1923-12-04
申请号：CA236186D
申请人： MERWIN WILLIAM M , BARR CLARENCE E , ALLEN FLORENCE KING , JACKSON THOMAS E , ALLEN FLORENCE KINK
发明人： MERWIN WILLIAM M , ALLEN FLORENCE KINK , BARR CLARENCE E , JACKSON THOMAS E , ALLEN FLORENCE KING

9. 发明专利

CA205858A ADJUSTABLE BALANCE FOR TONE ARMS 未知
公开(公告)号：CA205858A
公开(公告)日：1920-11-23
申请号：CA205858D
申请人： JACKSON THOMAS J
发明人： JACKSON THOMAS J

10. 发明专利

GB191413020A Improvements in and relating to Marine Engine Governors. 未知
公开(公告)号：GB191413020A
公开(公告)日：1915-05-27
申请号：GB191413020D
申请日：1914-05-27
申请人： RAMSAY ALLAN , JACKSON THOMAS
发明人： RAMSAY ALLAN , JACKSON THOMAS
摘要： 13,020. Ramsay, A., and Jackson, T. May 27. Stop-gear.-The speed of a marine engine is controlled by an inertia governor f, h, which actuates a fluid-pressure control valve k. When this valve is fully open, a pawl k engages a stop j on the valve spindle and prevents the spring from closing the valve.

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