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1. 发明授权

US08044058B2 Merocyanine derivatives 有权
标题翻译：梅花菁衍生物
公开(公告)号：US08044058B2
公开(公告)日：2011-10-25
申请号：US12715839
申请日：2010-03-02
申请人： Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
发明人： Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
IPC分类号： A61K31/517 , A61K31/445 , A61K31/16
CPC分类号： A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要： Disclosed is the use of merocyanine derivatives of formula Q is hydrogen; C1-C22alkyl; —OH; —OR7; —NR7R8; or —N═R9; R1 is hydrogen; C1-C22alkyl; —OR7, —SR7; —NR7R8; C1-C22alkyl; C2-C12 alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; —(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si—R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); —(CH2)u—O—(CH2)v—SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; for protecting of human hair and skin against the damaging effect of UV radiation.
摘要翻译：披露式Q的部花青衍生物的用途是氢; C 1 -C 22烷基; -哦; -OR7; -NR7R8; 或-N = R9; R1是氢; C 1 -C 22烷基; -OR7，-SR7; -NR7R8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12杂烷基，C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7，COOR7; CONR7R8; SO2（C6-C12）芳基; C2-C12烷-1-烯基; C 3 -C 12环烯-1-烯基; C2-C12alk-1-inyl; C 2 -C 12杂烷基; C3-C5杂环烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R5为-COR7; -COOR7; -OR7; -SR 7，-NHR 7，-NR 7 R 8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12烷基苯基; C 1 -C 12烷氧基-C 6 -C 10芳基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C 3 -C 12环杂烷基; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C 1 -C 22烷基; C1-C22烷氧基; 或COR7; R 7和R 8彼此独立地是氢; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; - （CH 2）t COOH; C7-C12芳烷基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C6-C10芳基; C1-C9杂芳基; Si-R10R11R12; Si（OR10）（OR11）（OR12）; SiR10（OR11）（OR12）; SiR10R11（OR12）; - （CH 2）u -O-（CH 2）v -SiR 10 R 11 R 12; 或基团X-Sil; t，u和v彼此独立地为1至5的数; R9是（C1-C6）亚烷基; R 10，R 11，R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。

2. 发明申请

US20100144753A1 CRYSTAL MODIFICATIONS OF TRANSMISSION DYES 有权
标题翻译：传染性染色体的晶体修饰
公开(公告)号：US20100144753A1
公开(公告)日：2010-06-10
申请号：US12597930
申请日：2008-04-28
申请人： Martin Vogt , Stefan Müller , Julie Grumelard , Cyrille Deshayes , Holger Paul , Jürg Haase , Thomas Ehlis
发明人： Martin Vogt , Stefan Müller , Julie Grumelard , Cyrille Deshayes , Holger Paul , Jürg Haase , Thomas Ehlis
IPC分类号： A61K31/4965
CPC分类号： C07D295/192 , A61K8/04 , A61K8/494 , A61K31/495 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic benzophenone derivative of formula (1), selected from the crystal modifications (B) and (C), wherein the crystal modification (B) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.70; and wherein the crystal modification (C) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.06; and (b) a dispersing agent selected from anionic, non-ionic and amphoteric surfactants; for protecting the human skin from browning and skin aging. The new crystal modification (C) represents a thermodynamically stable compound of formula (1) at 25° C. This modification is therefore suitable in dispersions comprising micro-fine particles.
摘要翻译：公开了含有（a）选自晶体改性（B）和（C）的式（1）的微粉化的微溶有机二苯甲酮衍生物的水性分散体的用途，其中所述晶体改性（B）的特征在于峰在X-射线衍射图中，d-间距约为7.70; 并且其中所述晶体改性（C）的特征在于在约7.06的d间距处的X射线衍射图中的峰; 和（b）选自阴离子，非离子和两性表面活性剂的分散剂; 用于保护人体皮肤免受褐变和皮肤老化。新的结晶改性（C）在25℃下代表热力学稳定的式（1）化合物。因此，该修饰适用于包含微细颗粒的分散体。

3. 发明授权

US07772242B2 Merocyanine derivatives 有权
公开(公告)号：US07772242B2
公开(公告)日：2010-08-10
申请号：US11630489
申请日：2005-06-20
申请人： Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
发明人： Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
IPC分类号： A61K31/519 , A61K31/445 , A61K31/16 , A61K31/165
CPC分类号： A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要： Disclosed is the use of the compounds of formula wherein Q is —OH; —OR7; —NH2; —NHR7; —NR7R8; or —N═R9; T is —COR5; —CN; or —SO2—(C6-C12)aryl; R1 is hydrogen; —OR7, —SR7; —NHR7; —NR7R8; C1-C22alkyl; C2-C12Alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R2 and R3 independently from each other are C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl, C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C3-C12cycloheteroalkyl; C2-C11heteroaralkyl, C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONH2; CONHR7; CONR7R8; SO2(C6-C12)aryl, C2-C12alk-1 -enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl, C3-C5heterocycloalkyl, C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl or C1-C9heteroaryl; R6, R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; o-C6-C10aryl; or C1-C9heteroaryl; R9 is a (C1-C6)alkylidene radical; or R1 and R2, R1 and Q, R1 and R4, R1 and R6, R2 and R3, R3 and Q, R6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocycic rings, and each N atom in a N-heterocyclic ring may be substituted by C1-C22alkyl; and n is a number from 1 to 4; for protecting of human hair and skin against the damaging effect of UV radiation.

4. 发明申请

US20090220439A1 Hydroxybenzophenone Derivatives 有权
标题翻译：羟基二苯甲酮衍生物
公开(公告)号：US20090220439A1
公开(公告)日：2009-09-03
申请号：US12223686
申请日：2007-02-06
申请人： Jürg Haase , Stefan Müller , Thomas Ehlis
发明人： Jürg Haase , Stefan Müller , Thomas Ehlis
IPC分类号： A61K8/58 , C07F7/10 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/585 , C07F7/0838
摘要： Disclosed are hydroxyphenylbenzophenone derivatives of formula (1), wherein R1 and R2 independently from each other are hydrogen; C1-C20alkenyl; C3-C10cycloalkyl; or R1 and R2 together with the linking nitrogen atom form a 5- 6-membered heterocyclic ring; R3, R4 and R5 independently from each other are C1-C4alkyl; C1-C4alkoxy; or a radical of formula (1a) R6 is C1-C6alkyl; and A is a straight-chain or branched C3-C6alkylene, which is optionally interrupted by one or more *—O—*, or *—O—(CO)—* groups; and m is 0; or a number from 1 to 5. The compounds are useful as cosmetic UV filters with outstanding solubility properties in cosmetic oils.
摘要翻译：公开了式（1）的羟基苯基二苯甲酮衍生物，其中R 1和R 2彼此独立地是氢; C1-C20烯基; C 3 -C 10环烷基; 或R 1和R 2与连接氮原子一起形成5-6元杂环; R 3，R 4和R 5彼此独立地为C 1 -C 4烷基; C1-C4烷氧基; 或式（1a）的基团，R 6为C 1 -C 6烷基; 并且A是直链或支链C 3 -C 6亚烷基，其任选地被一个或多个* -O- *或* -O-（CO）*基团间隔; m为0; 或1至5的数字。该化合物可用作化妆品油中具有优异溶解性的化妆品UV过滤器。

5. 发明申请

US20100209466A1 MEROCYANINE DERIVATIVES 有权
标题翻译：月桂酰胺衍生物
公开(公告)号：US20100209466A1
公开(公告)日：2010-08-19
申请号：US12715839
申请日：2010-03-02
申请人： Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
发明人： Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
IPC分类号： A61K8/41 , A61Q17/04 , A61K8/49 , A61K8/42 , A61K8/46 , A61K8/58 , A61K8/898 , A61K8/02
CPC分类号： A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要： Disclosed is the use of merocyanine derivatives of formula Q is hydrogen; C1-C22alkyl; —OH; —OR7; —NR7R8; or —N═R9; R1 is hydrogen; C1-C22alkyl; —OR7, —SR7; —NR7R8; C1-C22alkyl; C2-C12 alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; —(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si—R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); —(CH2)u—O—(CH2)v—SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; for protecting of human hair and skin against the damaging effect of UV radiation.
摘要翻译：公开了使用式Q的部花青衍生物是氢; C 1 -C 22烷基; -哦; -OR7; -NR7R8; 或-N = R9; R1是氢; C 1 -C 22烷基; -OR7，-SR7; -NR7R8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12杂烷基，C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7，COOR7; CONR7R8; SO2（C6-C12）芳基; C2-C12烷-1-烯基; C 3 -C 12环烯-1-烯基; C2-C12alk-1-inyl; C 2 -C 12杂烷基; C3-C5杂环烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R5是-COR7; -COOR7; -OR7; -SR 7，-NHR 7，-NR 7 R 8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12烷基苯基; C 1 -C 12烷氧基-C 6 -C 10芳基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C 3 -C 12环杂烷基; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C 1 -C 22烷基; C1-C22烷氧基; 或COR7; R 7和R 8彼此独立地是氢; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; - （CH 2）t COOH; C7-C12芳烷基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C6-C10芳基; C1-C9杂芳基; Si-R10R11R12; Si（OR10）（OR11）（OR12）; SiR10（OR11）（OR12）; SiR10R11（OR12）; - （CH 2）u -O-（CH 2）v -SiR 10 R 11 R 12; 或X-Sil基团; t，u和v彼此独立地为1至5的数; R9是（C1-C6）亚烷基; R 10，R 11，R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。

6. 发明授权

US07374749B2 Amino substituted hydroxyphenyl benzophenone derivatives 有权
标题翻译：氨基取代羟苯基二苯甲酮衍生物
公开(公告)号：US07374749B2
公开(公告)日：2008-05-20
申请号：US10537940
申请日：2003-12-03
申请人： Jürg Haase , Thomas Ehlis , Elek Borsos , Stefan Müller
发明人： Jürg Haase , Thomas Ehlis , Elek Borsos , Stefan Müller
IPC分类号： A61K8/44 , A61K8/49 , C07D277/66 , C07D313/12 , C07C233/73 , C07C233/69 , C07C233/78 , C07C229/52
CPC分类号： C07D295/192 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/4973 , A61Q17/04 , C07C229/52 , C07C237/32 , C07C237/34 , C07C237/40 , C07C237/42 , C07D277/46 , C07D277/66 , C07D313/12
摘要： Described are amino substituted hydroxyphenyl benzophenone derivatives of formula (I), wherein R1, and R2 independently from each other are; C1-C20alkyl; C2-C20-alkenyl; C3-C10cycloalkyl; C3-C10cycloalkenyl; or R1, and R2 together with the linking nitrogen atom form a 5- or 6-membered heterocyclic ring; n1 is a number from 1 to 4; when n1=1, R3 is a saturated or unsaturated heterocyclic radical; hydroxy-C1-C5alkyl; cyclohexyl optionally substituted with one or more C1-C5alkyl; phenyl optionally substituted with a heterocyclic radical, aminocarbonyl or C1-C5alkylcarboxy; when n1 is 2, R3 is an alkylene-, cycloalkylene- or alkenylene radical which is optionally substituted by a carbonyl- or carboxy group; o R3 together with A forms a bivalent radical of the formula (Ia), wherein n2 is a number from 1 to 3; when n1 is 3, R3 is an alkanetriyl radical; when n1 is 4, R3 is an alkanetetrayl radical; A is —O—; or —N(R5)—; and R5 is hydrogen; C1-C5alkyl; or hydroxy-C1-C5alkyl. The compounds are useful as UV filters in sunscreen applications.
摘要翻译：描述了式（I）的氨基取代的羟基苯基二苯甲酮衍生物，其中R 1和R 2彼此独立地是; C 1 -C 20烷基; C 1 -C 20烷基; C 2 -C 20 - 烯基; C 3 -C 10环烷基; C 3 -C 10环烯基; 或R 1和R 2与连接氮原子一起形成5-或6-元杂环; n 1是1至4的数; 当n 1 = 1时，R 3 3是饱和或不饱和杂环基; 羟基-C 1 -C 5烷基; 任选被一个或多个C 1 -C 5烷基取代的环己基; 任选被杂环基取代的苯基，氨基羰基或C 1 -C 5烷基羧基; 当n 1是2时，R 3是任选被羰基或羧基取代的亚烷基 - 亚环烷基 - 或亚烯基; R 3与A一起形成式（Ia）的二价基团，其中n 2是1至3的数; 当n 1为3时，R 3为烷三基; 当n 1为4时，R 3为烷基乙酰基; A为-O- 或-N（R 5） - ; 并且R 5是氢; C 1 -C 5烷基; 或羟基-C 1 -C 5烷基。这些化合物可用作防晒霜中的紫外线过滤器。

7. 发明授权

US08557820B2 Crystal modifications of transmission dyes 有权
标题翻译：透射染料的水晶修饰
公开(公告)号：US08557820B2
公开(公告)日：2013-10-15
申请号：US12597930
申请日：2008-04-28
申请人： Martin Vogt , Stefan Müller , Julie Grumelard , Cyrille Deshayes , Holger Paul , Jürg Haase , Thomas Ehlis
发明人： Martin Vogt , Stefan Müller , Julie Grumelard , Cyrille Deshayes , Holger Paul , Jürg Haase , Thomas Ehlis
IPC分类号： A61K31/497 , A61K8/00 , C07D241/04 , C07D295/00 , A61Q17/04
CPC分类号： C07D295/192 , A61K8/04 , A61K8/494 , A61K31/495 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic benzophenone derivative of formula (1), selected from the crystal modifications (B) and (C), wherein the crystal modification (B) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.70; and wherein the crystal modification (C) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.06; and (b) a dispersing agent selected from anionic, non-ionic and amphoteric surfactants; for protecting the human skin from browning and skin aging. The new crystal modification (C) represents a thermodynamically stable compound of formula (1) at 25° C. This modification is therefore suitable in dispersions comprising micro-fine particles.
摘要翻译：公开了含有（a）选自晶体改性（B）和（C）的式（1）的微粉化的微溶有机二苯甲酮衍生物的水性分散体的用途，其中所述晶体改性（B）的特征在于峰在X-射线衍射图中，d-间距约为7.70; 并且其中所述晶体改性（C）的特征在于在约7.06的d间距处的X射线衍射图中的峰; 和（b）选自阴离子，非离子和两性表面活性剂的分散剂; 用于保护人体皮肤免受褐变和皮肤老化。新的结晶改性（C）在25℃下代表热力学稳定的式（1）化合物。因此，该修饰适用于包含微细颗粒的分散体。

8. 发明授权

US08097240B2 Use of transmission dyes for protecting human skin from browning and ageing 有权
标题翻译：使用透射染料保护人体皮肤免受褐变和老化
公开(公告)号：US08097240B2
公开(公告)日：2012-01-17
申请号：US12086648
申请日：2006-12-11
申请人： Stefan Müller , Jürg Haase , Thomas Ehlis , Gilbert Kreyer , Jochen Giesinger , Martin Vogt
发明人： Stefan Müller , Jürg Haase , Thomas Ehlis , Gilbert Kreyer , Jochen Giesinger , Martin Vogt
IPC分类号： A61Q17/04 , C07D241/04
CPC分类号： C07D295/192 , A61K8/411 , A61K8/42 , A61K8/49 , A61K8/494 , A61K2800/43 , A61Q17/04
摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic compound which has a UV-Vis spectrum with a maximum from 380 to 420 nm; and (b) an anionic dispersing agent for protecting the human skin from browning and skin aging.
摘要翻译：公开了包含（a）微波化的微溶有机化合物的水分散体的使用，其具有最大值为380至420nm的UV-Vis光谱; 和（b）用于保护人体皮肤免于褐变和皮肤老化的阴离子分散剂。

9. 发明授权

US07999128B2 Hydroxybenzophenone derivatives 有权
标题翻译：羟基二苯甲酮衍生物
公开(公告)号：US07999128B2
公开(公告)日：2011-08-16
申请号：US12223686
申请日：2007-02-06
申请人： Jürg Haase , Stefan Müller , Thomas Ehlis
发明人： Jürg Haase , Stefan Müller , Thomas Ehlis
IPC分类号： C07F7/04
CPC分类号： A61Q17/04 , A61K8/585 , C07F7/0838
摘要： Disclosed are hydroxyphenylbenzophenone derivatives of formula (1), wherein R1 and R2 independently from each other are hydrogen; C1-C20alkenyl; C3-C10cycloalkyl; or R1 and R2 together with the linking nitrogen atom form a 5- 6-membered heterocyclic ring; R3, R4 and R5 independently from each other are C1-C4alkyl; C1-C4alkoxy; or a radical of formula (1a) R6 is C1-C6alkyl; and A is a straight-chain or branched C3-C6alkylene, which is optionally interrupted by one or more *—O—*, or *—O—(CO)—* groups; and m is 0; or a number from 1 to 5. The compounds are useful as cosmetic UV filters with outstanding solubility properties in cosmetic oils.
摘要翻译：公开了式（1）的羟基苯基二苯甲酮衍生物，其中R 1和R 2彼此独立地是氢; C1-C20烯基; C 3 -C 10环烷基; 或R 1和R 2与连接氮原子一起形成5-6元杂环; R 3，R 4和R 5彼此独立地为C 1 -C 4烷基; C1-C4烷氧基; 或式（1a）的基团，R 6为C 1 -C 6烷基; 并且A是直链或支链C 3 -C 6亚烷基，其任选地被一个或多个* -O- *或* -O-（CO）*基团间隔; m为0; 或1至5的数字。该化合物可用作化妆品油中具有优异溶解性的化妆品UV滤光片。

10. 发明授权

US07344706B2 UV absorber compositions comprising a hydroxyphenyltriazine compound 有权
标题翻译：包含羟基苯基三嗪化合物的紫外线吸收剂组合物
公开(公告)号：US07344706B2
公开(公告)日：2008-03-18
申请号：US10507295
申请日：2003-03-04
申请人： Jürg Haase , Thomas Ehlis , Elek Borsos , Dietmar Hüglin , Bernd Herzog
发明人： Jürg Haase , Thomas Ehlis , Elek Borsos , Dietmar Hüglin , Bernd Herzog
IPC分类号： A61Q17/00 , A61Q17/04 , A61Q19/00 , A61K8/02 , A61K31/53
CPC分类号： A61K8/4966 , A61Q17/04
摘要： UV absorber compositions are described, comprising (a) from 1 to 99% by weight of a hydroxyphenyltriazine compound of formula (I) wherein R1, R2 and R3 are each independently of the others C1-C18alkyl; C2-C10,alkenyl; or phenyl-C1-C4 alkyl; R4 is hydrogen; or C1-C5alkyl; and (b) from 99 to 1% by weight of a further UV absorber selected from the group of (b) hydroxyphenyltriazines that are different from component (a), (b2) benzotriazoles, (b3) dibenzoylmethane derivatives and (b4) camphor derivatives. The compositions are suitable as UV filters in cosmetic compositions
摘要翻译：描述了UV吸收剂组合物，其包含（a）1至99重量％的式（I）的羟基苯基三嗪化合物，其中R 1，R 2和R 2 > 3 各自独立地为C 1 -C 12烷基; C 2 -C 10，烯基; 或苯基-C 1 -C 4烷基; R 4是氢; 或C 1 -C 5烷基; （b）99〜1重量％的另外的紫外线吸收剂，其选自（b）不同于组分（a），（b-2）苯并三唑的（b）羟基苯基三嗪，（b < （3/4）二苯甲酰甲烷衍生物和（b 4 S）樟脑衍生物。该组合物适用于化妆品组合物中的UV过滤器

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