专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

2. 发明专利

JP2010513344A Plant extracts for use in the activity changes in the brain 审中-公开
公开(公告)号：JP2010513344A
公开(公告)日：2010-04-30
申请号：JP2009541831
申请日：2007-12-11
申请人：インターメッドディスカヴァリーゲゼルシャフトミットベシュレンクテルハフツングInterMed Discovery GmbH
发明人：レーマーエルンスト , グローテトルステン
IPC分类号： A61K31/11 , A23L1/30 , A61K36/00 , A61K36/18 , A61P3/00 , A61P25/00 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28
CPC分类号： C07C47/57 , C07C47/575 , C07C49/757 , C07C49/83 , C07C49/84
摘要： Compounds obtainable from plants, e.g. of the genus Eucalyptus, or from microorganisms are shown to be useful as CNS activity modulators useful e.g. in the treatment of depression, for lifting mood and/or for increasing behavioural initiative and the like. This use and related aspects form embodiments of the invention. Also compounds as such are presented. The compounds useful are acylphloroglucine derivatives of the formula I, wherein the substituents are as defined in the description.

3. 发明专利

JP2012510964A Hif-1 protein accumulation of inhibitor 审中-公开
公开(公告)号：JP2012510964A
公开(公告)日：2012-05-17
申请号：JP2011538897
申请日：2009-12-03
申请人：インターメッド・ディスカバリー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングInterMed Discovery GmbH
发明人：トーマス・ヘンケル , フィリップ・ヴァプニッツ , マティアス・ゲーリング , リーンハルト・エンメ・シュミッツ
IPC分类号： C07D307/77 , A61K31/343 , A61P9/00 , A61P11/00 , A61P11/16 , A61P13/00 , A61P13/12 , A61P15/00 , A61P15/08 , A61P19/02 , A61P27/02 , A61P27/06 , A61P29/00
CPC分类号： A61K31/343 , C07D307/93
摘要：本発明は、血管形成関連の障害の治療および／または予防のためのシクロペンタベンゾフラン誘導体に関する。

4. 发明专利

JP2010536720A Extract in combination with liver x receptor modulators, their use in the compounds and, in particular weight control 审中-公开
公开(公告)号：JP2010536720A
公开(公告)日：2010-12-02
申请号：JP2010520449
申请日：2008-07-29
申请人：インターメッド・ディスカバリー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングInterMed Discovery GmbH
发明人：エルンスト・レーマー , トーマス・ヘンケル , トルステン・グローテ
IPC分类号： A61K31/09 , A23L1/30 , A61K31/36 , A61K36/18 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , A61P43/00
CPC分类号： A61K31/36 , A61K31/085 , A61K31/09 , A61K31/215 , A61K31/222 , A61K31/343 , A61K36/57 , A61K36/79
摘要： The invention relates to the use, or methods (especially with regard to animals, especially human, that are in need of such treatment) comprising the use, of an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from the group consisting of Schisandra, Illicium, Kadsura, Steganotaenia and Magnolia, alone or as supplement, as active ingredient in the regulation of body weight and/or fat loss and/or for the management of obesity, either in humans or in animals, to the use of said extract and/or natural compound(s) or mixtures in the manufacture of a pharmaceutical or nutraceutical formulation for the regulation of body weight and/or fat loss and/or for the management of obesity either in humans or in animals. The above extract and/or compound(s) can further be used to reduce one or more adverse metabolic parameters in a subject, such as the blood cholesterol level, especially the "bad" low density lipid (LDL) cholesterol. The invention relates also to said extract and/or compound(s) for use in the treatment or in the preparation of a medicament for the treatment of obesity and/or elevated blood cholesterol, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s) which are useful in the regulation of body weight and/or fat loss and/or for the management of obesity.

5. 发明专利

TW200827362A 克里鮑林素(cripowellins)及其衍生物於治療腫瘤疾病之用途 USES OF CRIPOWELLINS AND DERIVATIVES THEREOF IN THE TREATMENT OF TUMORAL DISEASES 审中-公开
简体标题：克里鲍林素(cripowellins)及其衍生物于治疗肿瘤疾病之用途 USES OF CRIPOWELLINS AND DERIVATIVES THEREOF IN THE TREATMENT OF TUMORAL DISEASES
公开(公告)号：TW200827362A
公开(公告)日：2008-07-01
申请号：TW096134850
申请日：2007-09-19
申请人：英特梅德發現有限公司 INTERMED DISCOVERY GMBH
发明人：馬提亞斯葛靈 GEHLING, MATTHIAS , 歐拉夫韋伯 WEBER, OLAF
IPC分类号： C07D , A61K , C07H , A61P
CPC分类号： A61K31/55 , A61K31/7052
摘要：本發明係關於克里鮑黴素(cripowellins)及其衍生物在製備用以治療腫瘤疾病之醫藥組合物上的用途。
简体摘要：本发明系关于克里鲍霉素(cripowellins)及其衍生物在制备用以治疗肿瘤疾病之医药组合物上的用途。

6. 发明申请

US20130143959A1 EXTRACTS WITH LIVER-X-RECEPTOR MODULATORS, COMPOUNDS AND THEIR USE ESPECIALLY IN WEIGHT CONTROL 审中-公开
标题翻译：与肝脏受体调节剂，化合物及其在体重控制中特别有用的提取物
公开(公告)号：US20130143959A1
公开(公告)日：2013-06-06
申请号：US13680996
申请日：2012-11-19
申请人： INTERMED DISCOVERY GMBH
发明人： Torsten Grothe , Ernst Roemer , Thomas Henkel
IPC分类号： A61K31/36 , A61K31/222 , A61K31/09
CPC分类号： A61K31/36 , A61K31/085 , A61K31/09 , A61K31/215 , A61K31/222 , A61K31/343 , A61K36/57 , A61K36/79
摘要： The invention relates to an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from Schisandra, Illicium, Kadsura, Steganotaenia or Magnolia, for the regulation of body weight, fat loss, and/or management of obesity, in humans or in animals, methods and uses of the same and to the use of the same or mixtures in the manufacture of a pharmaceutical or nutraceutical formulation. The above can further be used to reduce one or more adverse metabolic parameters in a subject. The invention relates also to said extract and/or compound(s) in the treatment or in the preparation of a medicament for treatment of obesity, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s), which are useful in the regulation of body weight and/or fat loss and/or for the management of obesity.
摘要翻译：本发明涉及分别来自五味子，Illicium，Kadsura，Steganotaenia或Magnolia的来自植物或植物部分的提取物和/或一种或多种天然化合物，用于调节体重，脂肪减少和/ 或管理肥胖症，人或动物，其方法和用途，以及在制造药物或营养制剂中使用相同或混合物。上述可进一步用于减少受试者中的一种或多种不利代谢参数。本发明还涉及所述提取物和/或化合物在治疗或制备用于治疗肥胖症的药物及其制备中的用途。它还涉及包含所述提取物和/或天然化合物的药物或营养制剂，其可用于调节体重和/或脂肪减少和/或用于肥胖的治疗。

7. 发明申请

WO2011151298A1 PRODUCTION OF FATTY ACIDS BY HETEROLOGOUS EXPRESSION OF GENE CLUSTERS FROM MYXOBACTERIA 审中-公开
标题翻译：从MYXOBACTERIA通过异源表达基因簇产生脂肪酸
公开(公告)号：WO2011151298A1
公开(公告)日：2011-12-08
申请号：PCT/EP2011/058863
申请日：2011-05-30
申请人： INTERMED DISCOVERY GMBH , WENZEL, Silke , RACHID, Shwan , GEMPERLEIN, Katja , MÜLLER, Rolf
发明人： WENZEL, Silke , RACHID, Shwan , GEMPERLEIN, Katja , MÜLLER, Rolf
IPC分类号： C12P7/64 , C12N9/02 , C12N9/10 , C12N15/52
CPC分类号： C12P7/6427 , C12N9/001 , C12N9/1029 , C12N15/52 , C12P7/64 , C12Y103/01009 , C12Y203/01051 , Y02P20/52
摘要： The invention relates to a process for producing one or more polyunsaturated fatty acids by means of heterologous gene expression comprising the steps of providing a production organism which comprises a heterologous gene cluster encoding a polyunsaturated fatty acid biosynthetic pathway encompassing a subsequence ER encoding an enoylreductase and a subsequence AT encoding an acyltransferase, growing the production organism in the presence of a fermentable carbon source whereby one or more polyunsaturated fatty acids are produced, and optionally recovering the one or more polyunsaturated fatty acids.
摘要翻译：本发明涉及通过异源基因表达产生一种或多种多不饱和脂肪酸的方法，包括提供生产生物体的步骤，所述生物体包含编码多不饱和脂肪酸生物合成途径的异源基因簇，其包含编码烯酰基还原酶的亚序列ER，和亚序列AT编码酰基转移酶，在可发酵碳源的存在下生长生产生物体，从而产生一种或多种多不饱和脂肪酸，以及任选地回收一种或多种多不饱和脂肪酸。

8. 发明申请

WO2010063451A3 PRODUCTION OF OMEGA-3 FATTY ACIDS BY MYXOBACTERIA 审中-公开
公开(公告)号：WO2010063451A3
公开(公告)日：2010-06-10
申请号：PCT/EP2009/008560
申请日：2009-12-01
申请人： INTERMED DISCOVERY GMBH , STADLER, Marc , ROEMER, Ernst , MÜLLER, Rolf , GARCIA, Ronald O. , PISTORIUS, Dominik , BRACHMANN, Alexander
发明人： STADLER, Marc , ROEMER, Ernst , MÜLLER, Rolf , GARCIA, Ronald O. , PISTORIUS, Dominik , BRACHMANN, Alexander
IPC分类号： C12P7/64 , C12N1/20
摘要： The present invention provides a method for producing ω-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.

9. 发明申请

WO2010063451A2 PRODUCTION OF OMEGA-3 FATTY ACIDS BY MYXOBACTERIA 审中-公开
标题翻译：通过MYXOBACTERIA生产OMEGA-3脂肪酸
公开(公告)号：WO2010063451A2
公开(公告)日：2010-06-10
申请号：PCT/EP2009008560
申请日：2009-12-01
申请人： INTERMED DISCOVERY GMBH , STADLER MARC , ROEMER ERNST , MUELLER ROLF , GARCIA RONALD O , PISTORIUS DOMINIK , BRACHMANN ALEXANDER
发明人： STADLER MARC , ROEMER ERNST , MUELLER ROLF , GARCIA RONALD O , PISTORIUS DOMINIK , BRACHMANN ALEXANDER
IPC分类号： C12P7/64
CPC分类号： C12P7/6427 , C12R1/01
摘要： The present invention provides a method for producing ?-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.
摘要翻译：本发明提供通过培养适用于所述方法的特异性粘液细菌染色剂和粘液菌菌株来生产α-3多不饱和脂肪酸的方法。

10. 发明申请

WO2012079721A8 TERPENOID SPIRO KETAL COMPOUNDS WITH LXR AGONISTS ACTIVITY, THEIR USE AND FORMULATIONS WITH THEM 审中-公开
公开(公告)号：WO2012079721A8
公开(公告)日：2012-06-21
申请号：PCT/EP2011/006157
申请日：2011-12-08
申请人： INTERMED DISCOVERY GMBH , GROTHE, Torsten , STADLER, Marc , KÖPCKE, Bärbel , ROEMER, Ernst , BITZER, Jens , WABNITZ, Philipp , KÜPER, Thomas
发明人： GROTHE, Torsten , STADLER, Marc , KÖPCKE, Bärbel , ROEMER, Ernst , BITZER, Jens , WABNITZ, Philipp , KÜPER, Thomas
IPC分类号： A61K9/00 , A61K9/08 , A61K9/10 , A61K31/56 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P25/28
摘要： The invention relates to the use, or methods (especially with regard to animals, especially human, that are in need of such treatment) comprising the use, respectively, of an extract and/or especially one or more natural spiro triterpenoids and derivatives thereof, especially from the blazeispirol family, obtainable from Agaricus species, alone or as supplement, as active ingredient in the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, either in humans or in other mammals, and/or to the use of said extract and/or natural compound(s) or mixtures for the treatment of said disease, disorder or condition, as well as corresponding methods of treatment, or their use in the manufacture of a pharmaceutical or nutraceutical formulation for said treatment. The invention relates also to said extract and/or compound(s) for use in the treatment or in the preparation of a medicament (including a nutraceutical) for the prophylactic and/or therapeutic treatment of said disorder, disorder or condition, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations comprising said extract and/or natural compound(s) which are useful in said prophylactic and/or therapeutic treatment. They can also be used for non-therapeutic, e.g. cosmetic, purposes only.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式